clonidine has been researched along with Bipolar Disorder in 50 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Atomoxetine and OROS methylphenidate were successfully used concomitantly in a 10-year-old boy suffering from attention-deficit/hyperactivity disorder (ADHD) with comorbid bipolar disorder and Tourette syndrome (TS)." | 7.73 | Concomitant use of atomoxetine and OROS-methylphenidate in a 10-year-old child suffering from attention-deficit/hyperactivity disorder with comorbid bipolar disorder and Tourette syndrome. ( Benarroch, F; Gross-Tsur, V; Jaworowski, S, 2006) |
| "In a mixed bipolar disorder patient, DST-positive, treated with neuroleptics and antidepressants, the addition of clonidine (up to 0." | 7.67 | Clonidine in the treatment of mixed bipolar disorder. ( Kontaxakis, V; Markianos, M; Markidis, M; Stefanis, C, 1989) |
| "7% females) with diagnosed bipolar disorder I and during their acute manic phase were randomly assigned either to the adjuvant clonidine (0." | 5.51 | Influence of adjuvant clonidine on mania, sleep disturbances and cognitive performance - Results from a double-blind and placebo-controlled randomized study in individuals with bipolar I disorder during their manic phase. ( Ahmadpanah, M; Brand, S; Dürsteler, KM; Jahangard, L; Keshavarzi, A; Pezeshki, R; Soltanian, AR, 2022) |
| "One patient's akathisia also appeared to respond to clonidine." | 5.27 | Clonidine in the treatment of mania and mixed bipolar disorder. ( Cohen, BM; Jonas, JM; Lipinski, JF; Zubenko, GS, 1984) |
| "Clonidine's actions and efficacy in mental disorders are reviewed and examined." | 5.06 | Psychiatric indications for clonidine: the neuropharmacologic and clinical basis. ( Bond, WS, 1986) |
| " Among the more important recent discoveries are the efficacy of the tricyclic antidepressants for panic disorder and agoraphobia with panic attacks; the use of the monoamine oxidase inhibitors for the above disorders and for atypical depression and hysteroid dysphoria; the use of propranolol for anxiety disorders and for uncontrollable violent outbursts; the antianxiety and antipanic effects of clonidine; and the usefulness of lithium in treating schizophrenia and schizoaffective disorder and for emotionally unstable character disorders." | 4.76 | Newer uses for older psychotropic medications. ( Liebowitz, MR, 1982) |
| "Atomoxetine and OROS methylphenidate were successfully used concomitantly in a 10-year-old boy suffering from attention-deficit/hyperactivity disorder (ADHD) with comorbid bipolar disorder and Tourette syndrome (TS)." | 3.73 | Concomitant use of atomoxetine and OROS-methylphenidate in a 10-year-old child suffering from attention-deficit/hyperactivity disorder with comorbid bipolar disorder and Tourette syndrome. ( Benarroch, F; Gross-Tsur, V; Jaworowski, S, 2006) |
| "In a mixed bipolar disorder patient, DST-positive, treated with neuroleptics and antidepressants, the addition of clonidine (up to 0." | 3.67 | Clonidine in the treatment of mixed bipolar disorder. ( Kontaxakis, V; Markianos, M; Markidis, M; Stefanis, C, 1989) |
| "Carbamazepine treatment of a patient with 48-hour rapid cycling led to a dampening of mood cycling, and prolonged rapid eye movement (REM) sleep latency." | 1.29 | The effect of carbamazepine on endocrine and sleep EEG variables in a patient with 48-hour rapid cycling, and healthy controls. ( Bahro, M; Berger, M; Gann, H; Hohagen, F; Müller, WE; Riemann, D, 1993) |
| "Carbamazepine treatment normalized REM sleep variables, damped the amplitude of mood cycling of the patient, increased TSH and decreased FT4." | 1.29 | 48-hour rapid cycling: results of psychopathometric, polysomnographic, PET imaging and neuro-endocrine longitudinal investigations in a single case. ( Berger, M; Dressing, H; Gann, H; Hohagen, F; Müller, WE; Riemann, D; Strauss, LG, 1993) |
| "Six patients with akathisia were treated with clonidine in an open, on-drug/off-drug trial." | 1.27 | Use of clonidine in treating neuroleptic-induced akathisia. ( Cohen, BM; Jonas, JM; Lipinski, JF; Zubenko, GS, 1984) |
| "One patient's akathisia also appeared to respond to clonidine." | 1.27 | Clonidine in the treatment of mania and mixed bipolar disorder. ( Cohen, BM; Jonas, JM; Lipinski, JF; Zubenko, GS, 1984) |
| "Our findings suggest that patients with endogenous depression are characterized by a subsensitivity of postsynaptic alpha-receptors or of structures related to them." | 1.26 | Effect of clonidine on growth hormone release in psychiatric patients and controls. ( Ackenheil, M; Hippius, H; Matussek, N; Müller, F; Schröder, HT; Schultes, H; Wasilewski, B, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (70.00) | 18.7374 |
| 1990's | 10 (20.00) | 18.2507 |
| 2000's | 2 (4.00) | 29.6817 |
| 2010's | 1 (2.00) | 24.3611 |
| 2020's | 2 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmadpanah, M | 1 |
| Pezeshki, R | 1 |
| Soltanian, AR | 1 |
| Jahangard, L | 1 |
| Dürsteler, KM | 1 |
| Keshavarzi, A | 1 |
| Brand, S | 1 |
| Abraham, J | 1 |
| Varadharajan, N | 1 |
| Spalzang, ST | 1 |
| Nachiyar, S | 1 |
| Menon, V | 1 |
| Mattingly, GW | 1 |
| Anderson, RH | 1 |
| Malatynska, E | 1 |
| Knapp, RJ | 1 |
| Jaworowski, S | 1 |
| Benarroch, F | 1 |
| Gross-Tsur, V | 1 |
| Adler, LE | 1 |
| Bell, J | 1 |
| Kirch, D | 1 |
| Friedrich, E | 1 |
| Freedman, R | 1 |
| Liebowitz, MR | 1 |
| Johnson, JM | 1 |
| Zubenko, GS | 2 |
| Cohen, BM | 2 |
| Lipinski, JF | 2 |
| Jonas, JM | 2 |
| Matussek, N | 1 |
| Ackenheil, M | 1 |
| Hippius, H | 1 |
| Müller, F | 1 |
| Schröder, HT | 1 |
| Schultes, H | 1 |
| Wasilewski, B | 1 |
| Goodnick, PJ | 1 |
| Meltzer, HY | 1 |
| Terkelsen, KG | 1 |
| Ansseau, M | 4 |
| Scheyvaerts, M | 1 |
| Doumont, A | 1 |
| Poirrier, R | 1 |
| Legros, JJ | 3 |
| Franck, G | 2 |
| Judd, LL | 1 |
| Parker, DC | 1 |
| Janowsky, DS | 1 |
| Segal, DS | 1 |
| Risch, SC | 1 |
| Huey, LY | 1 |
| Abensour, P | 1 |
| Jouvent, R | 3 |
| Lecrubier, Y | 4 |
| Ahsanuddin, K | 1 |
| Tollefson, GD | 1 |
| Jimerson, DC | 1 |
| Post, RM | 1 |
| Stoddard, FJ | 1 |
| Gillin, JC | 1 |
| Bunney, WE | 1 |
| Puech, AJ | 1 |
| Simon, P | 1 |
| Widlöcher, D | 3 |
| Sovner, R | 1 |
| Campbell, M | 1 |
| Cueva, JE | 1 |
| Schittecatte, M | 1 |
| Garcia-Valentin, J | 1 |
| Charles, G | 1 |
| Machowski, R | 1 |
| Pena-Othaitz, MJ | 1 |
| Mendlewicz, J | 1 |
| Wilmotte, J | 1 |
| Riemann, D | 2 |
| Gann, H | 2 |
| Hohagen, F | 2 |
| Bahro, M | 1 |
| Müller, WE | 2 |
| Berger, M | 2 |
| Strauss, LG | 1 |
| Dressing, H | 1 |
| Coupland, N | 1 |
| Glue, P | 1 |
| Trestman, RL | 1 |
| Lawrence, TL | 1 |
| Coccaro, EF | 1 |
| Harvey, P | 1 |
| Bernstein, D | 1 |
| Lawrence, EK | 1 |
| Condello, V | 1 |
| Mahon, T | 1 |
| Yang, RK | 1 |
| Knott, P | 1 |
| Kontaxakis, V | 1 |
| Markianos, M | 1 |
| Markidis, M | 1 |
| Stefanis, C | 1 |
| Pandey, GN | 1 |
| Janicak, PG | 2 |
| Javaid, JI | 1 |
| Davis, JM | 2 |
| Sharma, RP | 1 |
| Easton, M | 1 |
| Comaty, JE | 1 |
| Bakchine, S | 1 |
| Lacomblez, L | 1 |
| Benoit, N | 1 |
| Parisot, D | 1 |
| Chain, F | 1 |
| Lhermitte, F | 1 |
| Hauger, RL | 1 |
| Scheinin, M | 1 |
| Siever, LJ | 1 |
| Linnoila, M | 1 |
| Potter, WZ | 1 |
| von Frenckell, R | 2 |
| Cerfontaine, JL | 1 |
| Papart, P | 1 |
| Timsit-Berthier, M | 1 |
| Geenen, V | 1 |
| Stein, MB | 1 |
| Uhde, TW | 1 |
| Sandyk, R | 1 |
| Cookson, JC | 1 |
| Giannini, AJ | 2 |
| Pascarzi, GA | 1 |
| Loiselle, RH | 1 |
| Price, WA | 1 |
| Giannini, MC | 1 |
| Lesch, KP | 1 |
| Laux, G | 1 |
| Erb, A | 1 |
| Pfüller, H | 1 |
| Beckmann, H | 1 |
| Hardy, MC | 2 |
| Wålinder, J | 1 |
| Bond, WS | 1 |
| Maguire, J | 1 |
| Singh, AN | 1 |
| Houser, WL | 1 |
| Kerr, L | 1 |
| Lerer, B | 1 |
| Shen, WW | 1 |
7 reviews available for clonidine and Bipolar Disorder
| Article | Year |
|---|---|
Optimizing outcomes in ADHD treatment: from clinical targets to novel delivery systems.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Anxiety Disorders; Atomoxetine H | 2016 |
Dominant-submissive behavior as models of mania and depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bipolar Disorder; Clonidine; Depression; Disease M | 2005 |
Newer uses for older psychotropic medications.
Topics: Adrenergic beta-Antagonists; Agoraphobia; Anxiety Disorders; Bipolar Disorder; Clonidine; Depressive | 1982 |
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; | 1984 |
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder | 1995 |
Drug treatment of bipolar depression and mania.
Topics: Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Bromocriptine; Carbamazepine; Choline | 1985 |
Alternative therapies for bipolar disorder.
Topics: Ascorbic Acid; Bipolar Disorder; Bupropion; Carbamazepine; Choline; Clonazepam; Clonidine; Clorgylin | 1985 |
10 trials available for clonidine and Bipolar Disorder
| Article | Year |
|---|---|
Influence of adjuvant clonidine on mania, sleep disturbances and cognitive performance - Results from a double-blind and placebo-controlled randomized study in individuals with bipolar I disorder during their manic phase.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Clonidine; Cognition; Double-Blind Method; Female; Hu | 2022 |
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; | 1984 |
The effect of methadone on the behavioral and neuroendocrine responses of manic patients.
Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Clonidine; Growth Hormone; Humans; Hydrocor | 1982 |
Noradrenergic responses to clonidine in acute and remitted depressed male patients.
Topics: Acute Disease; Aged; Arousal; Bipolar Disorder; Blood Pressure; Clonidine; Cohort Studies; Depressiv | 1992 |
A double-blind, placebo-controlled trial of clonidine in the treatment of acute mania.
Topics: Adult; Bipolar Disorder; Clonidine; Double-Blind Method; Female; Humans; Male; Psychiatric Status Ra | 1989 |
Manic-like state after bilateral orbitofrontal and right temporoparietal injury: efficacy of clonidine.
Topics: Adult; Behavior; Bipolar Disorder; Brain; Carbamazepine; Clonidine; Cognition; Female; Frontal Lobe; | 1989 |
Comparison of clonidine and lithium in the treatment of mania.
Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Depression; Double-Blind Method; Human | 1986 |
Psychiatric indications for clonidine: the neuropharmacologic and clinical basis.
Topics: Animals; Anxiety; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug T | 1986 |
Efficacy of clonidine in 24 patients with acute mania.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Drug Administration | 1986 |
Clonidine and verapamil in the treatment of mania.
Topics: Bipolar Disorder; Clonidine; Humans; Verapamil | 1986 |
34 other studies available for clonidine and Bipolar Disorder
| Article | Year |
|---|---|
Clonidine in Lieu of Electroconvulsive Therapy (ECT) for Control of Acute Manic Excitement Amidst the COVID-19 Pandemic.
Topics: Bipolar Disorder; Clonidine; COVID-19; Electroconvulsive Therapy; Humans; Pandemics | 2022 |
Concomitant use of atomoxetine and OROS-methylphenidate in a 10-year-old child suffering from attention-deficit/hyperactivity disorder with comorbid bipolar disorder and Tourette syndrome.
Topics: Adrenergic Uptake Inhibitors; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivi | 2006 |
Psychosis associated with clonidine withdrawal.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Clonidine; Female; Humans; Hypertension, Malignant; M | 1982 |
Use of clonidine in treating neuroleptic-induced akathisia.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Anxiety Disorders; Bipolar D | 1984 |
Effect of clonidine on growth hormone release in psychiatric patients and controls.
Topics: Adult; Alcohol Drinking; Bipolar Disorder; Clonidine; Depressive Disorder; Female; Growth Hormone; H | 1980 |
Neurochemical changes during discontinuation of lithium prophylaxis. I. Increases in clonidine-induced hypotension.
Topics: Adult; Bipolar Disorder; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Female; Humans | 1984 |
Clonidine in the treatment of mania and mixed bipolar disorder.
Topics: Adolescent; Adult; Bipolar Disorder; Clonidine; Female; Humans; Male; Psychomotor Agitation | 1984 |
Mania after surreptitious discontinuation of clonidine.
Topics: Bipolar Disorder; Clonidine; Humans; Patient Compliance; Substance Withdrawal Syndrome; Tourette Syn | 1984 |
Concurrent use of REM latency, dexamethasone suppression, clonidine, and apomorphine tests as biological markers of endogenous depression: a pilot study.
Topics: Adult; Apomorphine; Bipolar Disorder; Clonidine; Depressive Disorder; Dexamethasone; Female; Growth | 1984 |
Noradrenergic drugs and affective disorders.
Topics: Adult; Albuterol; Bipolar Disorder; Clonidine; Female; Humans | 1982 |
Side effects of clonidine.
Topics: Affective Disorders, Psychotic; Bipolar Disorder; Clonidine; Delusions; Humans; Obsessive-Compulsive | 1982 |
Hyperadrenergic hypomania consequent to the abrupt cessation of clonidine.
Topics: Affective Disorders, Psychotic; Aged; Autonomic Nervous System Diseases; Bipolar Disorder; Clonidine | 1981 |
Preliminary trial of the noradrenergic agonist clonidine in psychiatric patients.
Topics: Adult; Bipolar Disorder; Blood Pressure; Clonidine; Depression; Dose-Response Relationship, Drug; Do | 1980 |
Antimanic effect of clonidine.
Topics: Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Clonidine; Droperidol; Drug Therapy, | 1980 |
Thioridazine withdrawal-induced behavioral deterioration treated with clonidine: two case reports.
Topics: Administration, Cutaneous; Anxiety Disorders; Bipolar Disorder; Clonidine; Dose-Response Relationshi | 1995 |
Efficacy of the 'clonidine REM suppression test (CREST)' to separate patients with major depression from controls; a comparison with three currently proposed biological markers of depression.
Topics: Adult; Anxiety Disorders; Arousal; Biomarkers; Bipolar Disorder; Clonidine; Depressive Disorder; Ele | 1995 |
The effect of carbamazepine on endocrine and sleep EEG variables in a patient with 48-hour rapid cycling, and healthy controls.
Topics: Adult; Affect; Bipolar Disorder; Carbamazepine; Clonidine; Electroencephalography; Hormones; Humans; | 1993 |
48-hour rapid cycling: results of psychopathometric, polysomnographic, PET imaging and neuro-endocrine longitudinal investigations in a single case.
Topics: Bipolar Disorder; Carbamazepine; Cerebral Cortex; Circadian Rhythm; Clonidine; Dose-Response Relatio | 1993 |
[Current data on bipolar disorders, epilepsy and spasticity. 4. Neuro-Forum, Dresden].
Topics: Baclofen; Bipolar Disorder; Clonidine; Epilepsy; Female; Humans; Male; Muscle Relaxants, Central; Mu | 1999 |
[Current data on bipolar disorders, epilepsy and spasm. 4th Neuro-Forum, Dresden].
Topics: Baclofen; Benzodiazepines; Bipolar Disorder; Clonidine; Epilepsy; Humans; Muscle Relaxants, Central; | 1999 |
Blunting of clonidine-stimulated growth hormone release in mania.
Topics: Biomarkers; Bipolar Disorder; Clonidine; Growth Hormone; Humans; Receptors, Adrenergic, alpha | 1992 |
Blunting growth hormone release in mania.
Topics: Bipolar Disorder; Clonidine; Desipramine; Growth Hormone; Humans; Receptors, Adrenergic, alpha | 1992 |
Clonidine in the treatment of mixed bipolar disorder.
Topics: Adult; Bipolar Disorder; Clonidine; Dexamethasone; Dopamine beta-Hydroxylase; Female; Homovanillic A | 1989 |
Increased 3H-clonidine binding in the platelets of patients with depressive and schizophrenic disorders.
Topics: Bipolar Disorder; Blood Platelets; Clonidine; Depressive Disorder; Desipramine; Humans; Imidazoline | 1989 |
Dissociation of norepinephrine turnover from alpha-2 responses after clorgiline.
Topics: Bipolar Disorder; Blood Pressure; Clonidine; Clorgyline; Depressive Disorder; Female; Growth Hormone | 1988 |
Neuroendocrine evaluation of catecholaminergic neurotransmission in mania.
Topics: Adult; Apomorphine; Bipolar Disorder; Brain; Clonidine; Depressive Disorder; Dopamine; Female; Growt | 1987 |
Cortisol response to clonidine in panic disorder: comparison with depressed patients and normal controls.
Topics: Adult; Agoraphobia; Bipolar Disorder; Clonidine; Depressive Disorder; Fear; Female; Humans; Hydrocor | 1988 |
Antimanic effects of clonidine and the endogenous opioid system.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Bipolar Disorder; Brain; Clonidine; Endorphins; Human | 1985 |
Hormonal response to a pharmacological challenge.
Topics: Apomorphine; Bipolar Disorder; Clonidine; Depressive Disorder; Growth Hormone; Humans; Thyrotropin; | 1988 |
Growth hormone (GH) responses to GH-releasing hormone in depression: correlation with GH release following clonidine.
Topics: Adult; Bipolar Disorder; Clonidine; Depressive Disorder; Female; Growth Hormone; Growth Hormone-Rele | 1988 |
Clonidine and neuroleptic-resistant mania.
Topics: Bipolar Disorder; Clonidine; Humans | 1988 |
The use of clonidine in psychiatric disorders. Preliminary clinical observations.
Topics: Anxiety Disorders; Bipolar Disorder; Clonidine; Humans; Mental Disorders; Panic; Psychophysiologic D | 1986 |
Clonidine. An effective anti-manic agent?
Topics: Adult; Bipolar Disorder; Clonidine; Female; Humans; Male; Middle Aged | 1987 |
Mania, clonidine, and dopamine.
Topics: Animals; Bipolar Disorder; Clonidine; Dopamine; Dopamine Antagonists; Humans | 1986 |