clonidine has been researched along with Bile Duct Obstruction in 5 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, the status of alpha(2)-adrenoceptors during cholestasis was investigated by the inhibitory effect of clonidine on the electrically stimulated contractions of mice vas deferens (MVD) and guinea pig ileum (GPI)." | 3.72 | Alpha-2-adrenoceptor hyporesponsiveness in isolated tissues of cholestatic animals: involvement of opioid and nitric oxide systems. ( Dehpour, AR; Demehri, S; Gaskari, SA; Mehr, SE; Namiranian, K; Rastegar, H; Roushanzamir, F; Shariftabrizi, A, 2003) |
| "Cholestasis is associated with vascular changes and in previous studies decreased response of visceral vessels of cholestatic animals to phenylephrine and acetylcholine has been shown." | 1.33 | alpha2-Adrenoceptor subsensitivity in mesenteric vascular bed of cholestatic rats: the role of nitric oxide and endogenous opioids. ( Borhani, AA; Dehpour, AR; Ebrahimi, F; Hajrasouliha, AR; Houshmand, G; Namiranian, K; Samini, M; Tavakoli, S, 2005) |
| "Cholestasis is associated with elevated plasma level of endogenous opioid peptides." | 1.31 | Clonidine attenuates naloxone-induced opioid-withdrawal syndrome in cholestatic mice. ( Arad, MA; Dehpour, AR; Namiranian, K; Samini, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andoh, T | 1 |
| Suzuki, K | 1 |
| Konno, M | 1 |
| Tsuneyama, K | 1 |
| Kuraishi, Y | 1 |
| Demehri, S | 1 |
| Namiranian, K | 3 |
| Mehr, SE | 1 |
| Rastegar, H | 1 |
| Shariftabrizi, A | 1 |
| Gaskari, SA | 1 |
| Roushanzamir, F | 1 |
| Dehpour, AR | 4 |
| Borhani, AA | 1 |
| Houshmand, G | 1 |
| Samini, M | 2 |
| Hajrasouliha, AR | 2 |
| Tavakoli, S | 2 |
| Ebrahimi, F | 2 |
| Jabehdar-Maralani, P | 1 |
| Sadeghipour, H | 1 |
| Dehghani, M | 1 |
| Shafaroodi, H | 1 |
| Arad, MA | 1 |
5 other studies available for clonidine and Bile Duct Obstruction
| Article | Year |
|---|---|
Pharmacological Characterization of a Novel Mouse Model of Cholestatic Pruritus.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic | 2020 |
Alpha-2-adrenoceptor hyporesponsiveness in isolated tissues of cholestatic animals: involvement of opioid and nitric oxide systems.
Topics: Animals; Catecholamines; Cholestasis; Clonidine; Dose-Response Relationship, Drug; Guinea Pigs; Male | 2003 |
alpha2-Adrenoceptor subsensitivity in mesenteric vascular bed of cholestatic rats: the role of nitric oxide and endogenous opioids.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agon | 2005 |
Modulated hemodynamic response to clonidine in bile duct-ligated rats: the role of nitric oxide.
Topics: Animals; Antihypertensive Agents; Bile Ducts; Blood Pressure; Bradycardia; Cholestasis; Clonidine; D | 2006 |
Clonidine attenuates naloxone-induced opioid-withdrawal syndrome in cholestatic mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholestasis; Clonidine; Disease Mo | 2001 |