clonidine has been researched along with Back Ache in 9 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind trial tizanidine (DS 103-282: 5-Chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole), a new muscle relaxant, was compared with diazepam in twenty in-patients suffering from acute paravertebral muscle spasm." | 9.05 | Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam. ( Fryda-Kaurimsky, Z; Müller-Fassbender, H, 1981) |
| "We studied 10 patients with chronic back pain who had claimed benefit with a previous extradural dose of clonidine 150 micrograms combined with local anaesthetic." | 5.07 | Single-dose, randomized, double-blind, double-dummy cross-over comparison of extradural and i.v. clonidine in chronic pain. ( Carroll, D; Glynn, C; Jadad, A; King, V; McQuay, H; Wiffen, P, 1993) |
| "In a double-blind trial tizanidine (DS 103-282: 5-Chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole), a new muscle relaxant, was compared with diazepam in twenty in-patients suffering from acute paravertebral muscle spasm." | 5.05 | Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam. ( Fryda-Kaurimsky, Z; Müller-Fassbender, H, 1981) |
| "Clonidine is a central alpha(2)-agonist antihypertensive used widely for opioid/alcohol withdrawal, attention deficit hyperactivity disorder and chronic pain management." | 3.83 | Intrathecal Clonidine Pump Failure Causing Acute Withdrawal Syndrome With 'Stress-Induced' Cardiomyopathy. ( Graudins, A; Lee, HM; Ruggoo, V, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, HM | 1 |
| Ruggoo, V | 1 |
| Graudins, A | 1 |
| Williams, BS | 1 |
| Wong, D | 1 |
| Amin, S | 1 |
| Holmfred, A | 1 |
| Stone, LS | 1 |
| Kitto, KF | 1 |
| Eisenach, JC | 1 |
| Fairbanks, CA | 1 |
| Wilcox, GL | 1 |
| Hennies, OL | 1 |
| Fryda-Kaurimsky, Z | 1 |
| Müller-Fassbender, H | 1 |
| Iakhno, NN | 1 |
| Damulin, IV | 1 |
| Chernenko, OA | 1 |
| Ianakaeva, TA | 1 |
| Kondrat'eva, ON | 1 |
| Kur'ianova, PT | 1 |
| Carroll, D | 1 |
| Jadad, A | 1 |
| King, V | 1 |
| Wiffen, P | 1 |
| Glynn, C | 1 |
| McQuay, H | 1 |
| Zenz, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase III, Multicenter, Randomized Study to Assess the Efficacy and Safety of 0,5 mg Tizaspray® Administered Intranasally Versus Sirdalud® 2 mg Tablets, in Patients With Acute Low Back Pain[NCT02934061] | Phase 3 | 117 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for clonidine and Back Ache
| Article | Year |
|---|---|
A new skeletal muscle relaxant (DS 103-282) compared to diazepam in the treatment of muscle spasm of local origin.
Topics: Adult; Aged; Back Pain; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method; Female; | 1981 |
Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam.
Topics: Acute Disease; Adult; Back Pain; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method; | 1981 |
[The efficacy of sirdalud in the drug therapy of pain in the spine].
Topics: Acute Disease; Adult; Aged; Analgesics; Back Pain; Chronic Disease; Clonidine; Female; Humans; Male; | 1994 |
Single-dose, randomized, double-blind, double-dummy cross-over comparison of extradural and i.v. clonidine in chronic pain.
Topics: Adult; Aged; Analgesia, Epidural; Back Pain; Clonidine; Double-Blind Method; Female; Humans; Injecti | 1993 |
5 other studies available for clonidine and Back Ache
| Article | Year |
|---|---|
Intrathecal Clonidine Pump Failure Causing Acute Withdrawal Syndrome With 'Stress-Induced' Cardiomyopathy.
Topics: Adrenergic alpha-2 Receptor Agonists; Back Pain; Chronic Pain; Clonidine; Electrocardiography; Equip | 2016 |
Case scenario: self-extraction of intrathecal pump medication with a concomitant intrathecal granulomatous mass.
Topics: Acetaminophen; Administration, Cutaneous; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, O | 2011 |
Failed intrathecal analgesia following severe, terminal cancer pain.
Topics: Amines; Analgesics; Anesthetics, Local; Back Pain; Bupivacaine; Catheterization; Clonidine; Cyclohex | 2004 |
ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A- or alpha-2C-adrenergic receptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Back P | 2007 |
[Clonidine for intrathecal pain therapy].
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Back Pain; Catheters, Indwelling; Clonidine; Fem | 1996 |