clonidine has been researched along with Autoimmune Diabetes in 24 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Clonidine, an alpha 2-adrenergic agonist, was used to treat three patients with "idiopathic" diabetic diarrhea after other treatments had failed: The volume of diarrhea declined significantly (p less than 0." | 7.67 | Treatment of diabetic diarrhea with clonidine. ( Chang, EB; Fedorak, RN; Field, M, 1985) |
| " Reduced alpha-adrenergic tone has been demonstrated in the enterocytes of diabetic rats, and its correction by clonidine might explain the beneficial effect that the drug has on diabetic diarrhea." | 3.68 | Effect of clonidine on gallbladder contraction and small bowel transit time in insulin-treated diabetics. ( Braverman, DZ; Goldstein, R; Jacobsohn, WZ; Lissi, J; Morali, GA, 1991) |
| " Clonidine, an alpha 2-adrenergic agonist, was used to treat three patients with "idiopathic" diabetic diarrhea after other treatments had failed: The volume of diarrhea declined significantly (p less than 0." | 3.67 | Treatment of diabetic diarrhea with clonidine. ( Chang, EB; Fedorak, RN; Field, M, 1985) |
| " There were no significant differences between the dose-response curves of the diabetic group with normal urinary albumin excretion and the non-diabetic group." | 2.68 | Selective enhancement of alpha 2-adrenoceptor-mediated vasoconstriction in insulin-dependent diabetic patients with microalbuminuria. ( Bodmer, CW; De Leeuw, PW; Janssen, M; Schaper, NC; Williams, G, 1995) |
| "A total of 34 patients with type 1 diabetes were studied under euglycemic conditions on two occasions (11 without microangiopathy, 10 with proliferative and preproliferative retinopathy previously treated by laser coagulation, 13 with microalbuminuria, and 12 healthy volunteers also were studied)." | 1.30 | Endothelium-dependent vasodilatation, plasma markers of endothelial function, and adrenergic vasoconstrictor responses in type 1 diabetes under near-normoglycemic conditions. ( De Haan, CH; De Leeuw, PW; Hamulyak, K; Houben, AJ; Huvers, FC; Schaper, NC; Schouten, H; Wolffenbuttel, BH, 1999) |
| "Patients with moderately controlled type I diabetes mellitus have normal baseline and stimulated GH concentrations after the administration of GHRH or clonidine compared with healthy controls, when corrected for age, body mass index and sex." | 1.29 | Growth hormone responses to growth hormone-releasing hormone and clonidine in patients with type I diabetes and in normal controls: effect of age, body mass index and sex. ( Blankestijn, PJ; Jacobs, ML; Nathoe, HM; Stijnen, T; Weber, RF, 1996) |
| "We studied 45 prepubertal children with IDDM (30 males, 15 females) over 1 year period." | 1.29 | Growth parameters, growth hormone (GH) response to clonidine and circulating insulin-like growth factor-I (IGF-I), free thyroxine (FT4) and cortisol concentrations in relation to glycaemic control in children with insulin-dependent diabetes mellitus. ( Ahmed, HI; Asfour, MG; Soliman, AT, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (54.17) | 18.7374 |
| 1990's | 10 (41.67) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghannoum, JE | 1 |
| Odingo, NA | 1 |
| Provost, N | 1 |
| Speroni, G | 2 |
| Ceda, GP | 1 |
| Capretti, L | 2 |
| Valenti, G | 1 |
| Parving, HH | 3 |
| Kastrup, H | 1 |
| Smidt, UM | 2 |
| Andersen, AR | 1 |
| Feldt-Rasmussen, B | 1 |
| Christiansen, JS | 1 |
| Bodmer, CW | 1 |
| Schaper, NC | 2 |
| Janssen, M | 1 |
| De Leeuw, PW | 2 |
| Williams, G | 1 |
| Jacobs, ML | 1 |
| Nathoe, HM | 1 |
| Blankestijn, PJ | 1 |
| Stijnen, T | 1 |
| Weber, RF | 1 |
| Soliman, AT | 1 |
| Ahmed, HI | 1 |
| Asfour, MG | 1 |
| Soergel, KH | 1 |
| Greenberger, NJ | 1 |
| Huvers, FC | 1 |
| Houben, AJ | 1 |
| De Haan, CH | 1 |
| Hamulyak, K | 1 |
| Schouten, H | 1 |
| Wolffenbuttel, BH | 1 |
| Almqvist, EG | 1 |
| Groop, LC | 1 |
| Manhem, PJ | 1 |
| Coiro, V | 1 |
| Volpi, R | 1 |
| Caffarri, G | 1 |
| Marchesi, C | 1 |
| Chiodera, P | 1 |
| Mourad, FH | 1 |
| Gorard, D | 1 |
| Thillainayagam, AV | 1 |
| Colin-Jones, D | 1 |
| Farthing, MJ | 1 |
| Di Mario, U | 1 |
| Bacci, S | 1 |
| Morano, S | 1 |
| Pugliese, G | 1 |
| Pietravalle, P | 1 |
| Andreani, D | 1 |
| Morabito, S | 1 |
| Simonetti, B | 1 |
| Pierucci, A | 1 |
| Morali, GA | 1 |
| Braverman, DZ | 1 |
| Lissi, J | 1 |
| Goldstein, R | 1 |
| Jacobsohn, WZ | 1 |
| Topper, E | 1 |
| Gertner, J | 1 |
| Amiel, S | 1 |
| Press, M | 1 |
| Genel, M | 1 |
| Tamborlane, WV | 1 |
| Giampietro, O | 1 |
| Ferdeghini, M | 1 |
| Miccoli, R | 1 |
| Locatelli, V | 1 |
| Cerri, M | 1 |
| Yanaihara, N | 1 |
| Navalesi, R | 1 |
| Müller, EE | 1 |
| Migliore, A | 1 |
| Barone, C | 1 |
| Manna, R | 1 |
| Greco, AV | 1 |
| Wittert, GA | 1 |
| Joffe, BI | 1 |
| Panz, VR | 1 |
| Shires, R | 1 |
| Baker, SG | 1 |
| Seftel, HC | 1 |
| Bretzke, G | 1 |
| Roof, LW | 1 |
| Hommel, E | 1 |
| Mathiesen, E | 1 |
| Edsberg, B | 1 |
| Bahnsen, M | 1 |
| Stroev, IuI | 1 |
| Leviashvili, BI | 1 |
| Fedorak, RN | 1 |
| Field, M | 1 |
| Chang, EB | 1 |
| Lanes, R | 1 |
| Recker, B | 1 |
| Fort, P | 1 |
| Lifshitz, F | 1 |
| Kastrup, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double Blind, Placebo Controlled, Cross Over Study to Investigate the Effectiveness and Safety of Eluxadoline in the Treatment of Diabetic Diarrhea[NCT04313088] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2022-07-01 | Withdrawn (stopped due to This study did not enroll any subjects) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for clonidine and Autoimmune Diabetes
| Article | Year |
|---|---|
Selective enhancement of alpha 2-adrenoceptor-mediated vasoconstriction in insulin-dependent diabetic patients with microalbuminuria.
Topics: Adult; Albuminuria; Clonidine; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Humans; | 1995 |
Enhancement of the GH responsiveness to GH releasing stimuli by lysine vasopressin in type 1 diabetic subjects.
Topics: Adult; Analysis of Variance; Arginine; Case-Control Studies; Clonidine; Diabetes Mellitus, Type 1; G | 1999 |
Selective decrement of anionic immunoglobulin clearance after induced renal hemodynamic changes in diabetic patients.
Topics: Adult; Albuminuria; Blood Glucose; Blood Pressure; Captopril; Clonidine; Diabetes Mellitus, Type 1; | 1992 |
Effect of growth hormone-releasing hormone and clonidine on growth hormone release in type 1 diabetic patients.
Topics: Adult; Clonidine; Diabetes Mellitus, Type 1; Female; Growth Hormone; Growth Hormone-Releasing Hormon | 1987 |
Acute reduction of arterial blood pressure reduces urinary albumin excretion in type 1 (insulin-dependent) diabetic patients with incipient nephropathy.
Topics: Adult; Albuminuria; Blood Pressure; Clonidine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Fe | 1986 |
19 other studies available for clonidine and Autoimmune Diabetes
| Article | Year |
|---|---|
Clinico-pathologic conference: case 6.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell; | 2009 |
Clonidine and GH secretion in insulin dependent diabetes (IDD).
Topics: Adolescent; Adult; Aged; Circadian Rhythm; Clonidine; Diabetes Mellitus, Type 1; Female; Growth Horm | 1983 |
Impaired autoregulation of glomerular filtration rate in type 1 (insulin-dependent) diabetic patients with nephropathy.
Topics: Adult; Albuminuria; Blood Pressure; Chromium; Chromium Radioisotopes; Clonidine; Diabetes Mellitus, | 1984 |
Growth hormone responses to growth hormone-releasing hormone and clonidine in patients with type I diabetes and in normal controls: effect of age, body mass index and sex.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Age Factors; Body Mass Index; Clonidine; Diabetes M | 1996 |
Growth parameters, growth hormone (GH) response to clonidine and circulating insulin-like growth factor-I (IGF-I), free thyroxine (FT4) and cortisol concentrations in relation to glycaemic control in children with insulin-dependent diabetes mellitus.
Topics: Body Mass Index; Case-Control Studies; Child; Child, Preschool; Clonidine; Diabetes Mellitus, Type 1 | 1996 |
Nausea and vomiting in the diabetic patient.
Topics: Adrenergic alpha-Agonists; Algorithms; Clonidine; Diabetes Mellitus, Type 1; Diagnosis, Differential | 1998 |
Endothelium-dependent vasodilatation, plasma markers of endothelial function, and adrenergic vasoconstrictor responses in type 1 diabetes under near-normoglycemic conditions.
Topics: Adrenergic alpha-Agonists; Adult; Biomarkers; Blood Glucose; Clonidine; Diabetes Mellitus, Type 1; E | 1999 |
Growth hormone response to the insulin tolerance and clonidine tests in type 1 diabetes.
Topics: Adult; Case-Control Studies; Clonidine; Diabetes Mellitus, Type 1; Female; Growth Hormone; Humans; I | 1999 |
Effective treatment of diabetic diarrhoea with somatostatin analogue, octreotide.
Topics: Adult; Clonidine; Diabetes Mellitus, Type 1; Diarrhea; Female; Gastrointestinal Transit; Humans; Oct | 1992 |
Effect of clonidine on gallbladder contraction and small bowel transit time in insulin-treated diabetics.
Topics: Adult; Breath Tests; Clonidine; Diabetes Mellitus, Type 1; Diarrhea; Female; Gallbladder; Gastrointe | 1991 |
Deranged alpha-adrenergic regulation of growth hormone secretion in poorly controlled diabetes: reversal of the exaggerated response to clonidine after continuous subcutaneous insulin infusion.
Topics: Adolescent; Adult; Blood Glucose; Clonidine; Diabetes Mellitus, Type 1; Female; Growth Hormone; Huma | 1985 |
Diabetic diarrhea and clonidine.
Topics: Adult; Clonidine; Diabetes Mellitus, Type 1; Diarrhea; Humans; Male | 1988 |
Hypoglycemic glucose counterregulation in healthy subjects pretreated with oral clonidine.
Topics: Clonidine; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Male | 1987 |
[Therapy of diarrhea in diabetic enteropathy with clonidine].
Topics: Aged; Clonidine; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Diarrhea; Female; Gastrointestina | 1987 |
Treatment of diabetic diarrhea with clonidine.
Topics: Administration, Cutaneous; Clonidine; Diabetes Mellitus, Type 1; Diarrhea; Female; Humans; Middle Ag | 1987 |
[Use of clofeline in arterial hypertension in diabetes mellitus].
Topics: Adult; Aged; Antihypertensive Agents; Clonidine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 1986 |
Treatment of diabetic diarrhea with clonidine.
Topics: Chronic Disease; Clonidine; Diabetes Mellitus, Type 1; Diarrhea; Feces; Humans; Substance Withdrawal | 1985 |
Impaired somatomedin generation test in children with insulin-dependent diabetes mellitus.
Topics: Administration, Oral; Adolescent; Blood Glucose; Child; Child, Preschool; Cholesterol; Clonidine; Di | 1985 |
Reduced transcapillary escape of albumin during acute blood pressure-lowering in type 1 (insulin-dependent) diabetic patients with nephropathy.
Topics: Adult; Blood Glucose; Capillary Permeability; Clonidine; Diabetes Mellitus, Type 1; Diabetic Angiopa | 1985 |