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clonidine and Aura

clonidine has been researched along with Aura in 19 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Research Excerpts

ExcerptRelevanceReference
" In cobalt-induced epilepsy in the rat activity is associated with a cortical NA denervation."8.77Chronic cobalt-induced epilepsy: noradrenaline ionophoresis and adrenoceptor binding studies in the rat cerebral cortex. ( Bregman, B; Chauvel, P; Le Saux, F; Maurin, Y; Trottier, S, 1985)
"Focal and convulsive seizure thresholds were evaluated 10-12 min postinfusion and compared to thresholds obtained during two interspersed control conditions (vehicle control = 1 microliter microinfusion of sterile saline; sham control = needle insertion only)."5.29The alpha 2-adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2-adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens: a comparison of amygdala and pontine microinfusion effects. ( Alcalde, O; Bier, M; Farber, PR; Langer, J; Moghimi, R; Richkind, M; Shouse, MN; Szymusiak, R, 1996)
" In cobalt-induced epilepsy in the rat activity is associated with a cortical NA denervation."4.77Chronic cobalt-induced epilepsy: noradrenaline ionophoresis and adrenoceptor binding studies in the rat cerebral cortex. ( Bregman, B; Chauvel, P; Le Saux, F; Maurin, Y; Trottier, S, 1985)
"We have investigated the influence of central noradrenergic and dopaminergic systems on the susceptibility of rats to seizures in the kainic acid (KA)-model of epilepsy."3.67Kainic acid-induced seizures: potentiation by alpha-methyl-p-tyrosine. ( Baran, H; Hornykiewicz, O; Hörtnagl, H, 1989)
"We found that the binding of [3H]prazosin, a selective ligand for alpha 1-adrenergic recognition sites, is significantly lower in the frontal cortex of the genetically epilepsy-prone rats (GEPRs), as compared with normal Sprague-Dawley rats."3.67Abnormality of alpha 1-adrenergic receptors in the frontal cortex of epileptic rats. ( Barbaccia, ML; Iadarola, MJ; Laird, HE; Nicoletti, F; Pozzi, O, 1986)
"Clonidine was the most common medication to be used and was well tolerated."1.48Implications of comorbid ADHD in ASD interventions and outcome: Results from a naturalistic follow up study from south India. ( Chandrasekaran, V; Kandasamy, P; Kuppili, PP; Manohar, H; Rajkumar, RP, 2018)
"Clonidine was most effective in temporal lobe epilepsy, when the focus was located in the right hemisphere, and when clonidine serum concentrations were ranging between 0."1.33Comparison of clonidine to sleep deprivation in the potential to induce spike or sharp-wave activity. ( Feichtinger, M; Hummel, C; Kaltenhäuser, M; Kettenmann, B; Stefan, H; Tilz, C, 2005)
"Pharmacological treatment of epilepsy is needed whenever epilepsy occurs."1.31[Medical treatment of fragile X syndrome]. ( Artigas-Pallarés, J; Brun-Gasca, C, 2001)
"Focal and convulsive seizure thresholds were evaluated 10-12 min postinfusion and compared to thresholds obtained during two interspersed control conditions (vehicle control = 1 microliter microinfusion of sterile saline; sham control = needle insertion only)."1.29The alpha 2-adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2-adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens: a comparison of amygdala and pontine microinfusion effects. ( Alcalde, O; Bier, M; Farber, PR; Langer, J; Moghimi, R; Richkind, M; Shouse, MN; Szymusiak, R, 1996)
"Pretreatment with reserpine had no effect on either the time to onset or duration of maximal dentate activation."1.28Cholinergic and adrenergic agents modify the initiation and termination of epileptic discharges in the dentate gyrus. ( Lothman, EW; Stringer, JL, 1991)
" These findings were confirmed and extended here with dose-response curves."1.28Neonatal clonidine treatment results in long-lasting changes in noradrenaline sensitivity and kindling epileptogenesis. ( Bos, NP; Gorter, JA; Huisman, E; Kamphuis, W; Mirmiran, M, 1990)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's7 (36.84)18.2507
2000's5 (26.32)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manohar, H1
Kuppili, PP1
Kandasamy, P1
Chandrasekaran, V1
Rajkumar, RP1
Vorobyov, V1
Schibaev, N1
Kaptsov, V1
Kovalev, G1
Sengpiel, F1
Artigas-Pallarés, J1
Brun-Gasca, C1
Kettenmann, B1
Feichtinger, M1
Tilz, C1
Kaltenhäuser, M1
Hummel, C1
Stefan, H1
Shouse, MN1
Langer, J1
Bier, M1
Farber, PR1
Alcalde, O1
Moghimi, R1
Richkind, M1
Szymusiak, R1
Yoshioka, S1
Mitani, H1
Maeda, K1
Takeo, S1
Matsuda, K1
Katayama, S1
Mizukawa, R1
Kawahara, R1
Scaramuzza, A1
Torresani, P1
Arisi, D1
Rossoni, R1
Niederhofer, H1
Metz, SA1
Halter, JB1
Porte, D1
Robertson, RP1
Chen, LS1
Weingart, JB1
McNamara, JO1
Lehmenkühler, C1
Walden, J1
Speckmann, EJ1
Stringer, JL1
Lothman, EW1
Gorter, JA1
Kamphuis, W1
Huisman, E1
Bos, NP1
Mirmiran, M1
Baran, H1
Hörtnagl, H1
Hornykiewicz, O1
Löscher, W1
Czuczwar, SJ1
Nicoletti, F1
Barbaccia, ML1
Iadarola, MJ1
Pozzi, O1
Laird, HE1
Bregman, B1
Le Saux, F1
Trottier, S1
Chauvel, P1
Maurin, Y1

Reviews

1 review available for clonidine and Aura

ArticleYear
Chronic cobalt-induced epilepsy: noradrenaline ionophoresis and adrenoceptor binding studies in the rat cerebral cortex.
    Journal of neural transmission, 1985, Volume: 63, Issue:2

    Topics: Animals; Cerebral Cortex; Chronic Disease; Clonidine; Cobalt; Dihydroalprenolol; Epilepsy; Iontophor

1985

Other Studies

18 other studies available for clonidine and Aura

ArticleYear
Implications of comorbid ADHD in ASD interventions and outcome: Results from a naturalistic follow up study from south India.
    Asian journal of psychiatry, 2018, Volume: 33

    Topics: Adrenergic alpha-2 Receptor Agonists; Attention Deficit Disorder with Hyperactivity; Autism Spectrum

2018
Cortical and hippocampal EEG effects of neurotransmitter agonists in spontaneously hypertensive vs. kainate-treated rats.
    Brain research, 2011, Apr-06, Volume: 1383

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Baclofen; Clonidine; Disease Models, Animal;

2011
[Medical treatment of fragile X syndrome].
    Revista de neurologia, 2001, Volume: 33 Suppl 1

    Topics: Adrenergic alpha-Agonists; Anticonvulsants; Antipsychotic Agents; Attention Deficit and Disruptive B

2001
Comparison of clonidine to sleep deprivation in the potential to induce spike or sharp-wave activity.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2005, Volume: 116, Issue:4

    Topics: Action Potentials; Adolescent; Adult; Clonidine; Epilepsy; Female; Humans; Magnetoencephalography; M

2005
The alpha 2-adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2-adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens: a comparison of amygdala and pontine microinfusion effects.
    Epilepsia, 1996, Volume: 37, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Cats; Clonidine; Dioxane

1996
[Current data on bipolar disorders, epilepsy and spasticity. 4. Neuro-Forum, Dresden].
    Fortschritte der Neurologie-Psychiatrie, 1999, Volume: 67, Issue:5 Suppl Ak

    Topics: Baclofen; Bipolar Disorder; Clonidine; Epilepsy; Female; Humans; Male; Muscle Relaxants, Central; Mu

1999
[Current data on bipolar disorders, epilepsy and spasm. 4th Neuro-Forum, Dresden].
    Psychiatrische Praxis, 1999, Volume: 26, Issue:3 Suppl

    Topics: Baclofen; Benzodiazepines; Bipolar Disorder; Clonidine; Epilepsy; Humans; Muscle Relaxants, Central;

1999
Age-specific effects of noradrenergic alpha-2 agonist clonidine on the development of amygdaloid kindling in developing rats.
    Brain research. Developmental brain research, 2000, Feb-07, Volume: 119, Issue:2

    Topics: Adrenergic alpha-Agonists; Aging; Amygdala; Animals; Anticonvulsants; Clonidine; Convulsants; Epilep

2000
Seizures following clonidine test for growth hormone reserve: unusual presentation of benign partial epilepsy.
    Journal of pediatric endocrinology & metabolism : JPEM, 2000, Volume: 13, Issue:4

    Topics: Child; Clonidine; Electroencephalography; Epilepsy; Human Growth Hormone; Humans; Magnetic Resonance

2000
[Therapy of tic disorders apparently of organic origin in a multi-morbid 5-year-old patient with lofexidine (Britlofex) and clonidine (Catapressan)].
    Wiener medizinische Wochenschrift (1946), 2001, Volume: 151, Issue:13-14

    Topics: Affective Symptoms; Aggression; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chronic

2001
Autonomic epilepsy: clonidine blockade of paroxysmal catecholamine release and flushing.
    Annals of internal medicine, 1978, Volume: 88, Issue:2

    Topics: Autonomic Nervous System; Carbamazepine; Catecholamines; Climacteric; Clonidine; Epilepsy; Epilepsy,

1978
Biochemical and radiohistochemical analyses of alpha-2 adrenergic receptors in the kindling model of epilepsy.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoradiography; Brain; Cell Membr

1990
Decrease of N-methyl-D-aspartate responses by noradrenaline in the rat motorcortex in vivo.
    Neuroscience letters, 1991, Jan-02, Volume: 121, Issue:1-2

    Topics: Animals; Clonidine; Electroencephalography; Epilepsy; Evoked Potentials; Isoproterenol; Motor Cortex

1991
Cholinergic and adrenergic agents modify the initiation and termination of epileptic discharges in the dentate gyrus.
    Neuropharmacology, 1991, Volume: 30, Issue:1

    Topics: Animals; Atropine; Clonidine; Electric Stimulation; Epilepsy; Hippocampus; Male; Parasympathomimetic

1991
Neonatal clonidine treatment results in long-lasting changes in noradrenaline sensitivity and kindling epileptogenesis.
    Brain research, 1990, Dec-03, Volume: 535, Issue:1

    Topics: Animals; Animals, Newborn; Clonidine; Electric Stimulation; Epilepsy; Iontophoresis; Kindling, Neuro

1990
Kainic acid-induced seizures: potentiation by alpha-methyl-p-tyrosine.
    Brain research, 1989, Aug-28, Volume: 495, Issue:2

    Topics: alpha-Methyltyrosine; Animals; Clonidine; Diazepam; Dopamine; Epilepsy; Kainic Acid; Male; Methyltyr

1989
Comparison of drugs with different selectivity for central alpha 1-and alpha 2-adrenoceptors in animal models of epilepsy.
    Epilepsy research, 1987, Volume: 1, Issue:3

    Topics: Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation;

1987
Abnormality of alpha 1-adrenergic receptors in the frontal cortex of epileptic rats.
    Journal of neurochemistry, 1986, Volume: 46, Issue:1

    Topics: Animals; Carbachol; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Epilepsy; Hippocam

1986