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clonidine and Asthma, Bronchial

clonidine has been researched along with Asthma, Bronchial in 18 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Research Excerpts

ExcerptRelevanceReference
"Fifteen patients with asthma were randomized into a double-blind, placebo controlled, crossover trial evaluating whether clonidine increased airway resistance."9.08Oral clonidine in patients with asthma: no significant effect on airway reactivity. ( Foxworth, JW; Knudson, SM; Pyszczynski, DR; Reisz, GR, 1995)
" The effects of pretreatment with clonidine and rilmenidine, a new alpha 2-adrenoceptor agonist, on the bronchial responses to inhaled histamine were studied on 3 different days in a controlled, double-blind, randomized study in 12 asymptomatic asthmatic subjects."9.06Comparative effects of rilmenidine and clonidine on bronchial responses to histamine in asthmatic subjects. ( Advenier, C; Dinh Xuan, AT; Lockhart, A; Matran, R; Regnard, J; Vitou, P, 1988)
"We investigated the possibility that clonidine, an alpha 2-adrenoceptor agonist, can reduce the wheal-and-flare reactions induced by intradermal injections of allergen in patients with extrinsic asthma."9.06Inhibitory effects of clonidine on the allergen-induced wheal-and-flare reactions in patients with extrinsic asthma. ( Andersson, RG; Brundin, A; Lindgren, BR, 1987)
" Results obtained in the present study showed that EZJF and JB significantly inhibited clonidine-induced catalepsy, milk-induced leucocytosis and eosinophilia, clonidine-induced mast cell degranulation, and passive paw anaphylaxis."7.91Antiasthmatic potential of Zizyphus jujuba Mill and Jujuboside B. - Possible role in the treatment of asthma. ( Ninave, PB; Patil, SD, 2019)
"To study the effect of inhaled clonidine on broncho-obstruction in asthmatics, 10 patients with extrinsic asthma were broncho-provoked twice with an allergen that had been shown to give positive skin prick test results."7.67The effect of inhaled clonidine in patients with asthma. ( Andersson, RG; Ekström, T; Lindgren, BR, 1986)
" The dose-response curves were compared by an analysis of variance."6.66Effects of clonidine on bronchial responses to histamine in normal and asthmatic subjects. ( Advenier, C; Dinh Xuan, AT; Lockhart, A; Mantrand, P; Matran, R; Regnard, J, 1988)
"Alinidine is a new bradycardic agent which has been shown to be beneficial in the treatment of coronary heart disease."6.66Safety and efficacy of alinidine in symptom-free asthmatics. ( Friedrich, T; Hoffmann, M; Huckauf, H; Kammradt, G; Lichey, J, 1986)
"Fifteen patients with asthma were randomized into a double-blind, placebo controlled, crossover trial evaluating whether clonidine increased airway resistance."5.08Oral clonidine in patients with asthma: no significant effect on airway reactivity. ( Foxworth, JW; Knudson, SM; Pyszczynski, DR; Reisz, GR, 1995)
" The effects of pretreatment with clonidine and rilmenidine, a new alpha 2-adrenoceptor agonist, on the bronchial responses to inhaled histamine were studied on 3 different days in a controlled, double-blind, randomized study in 12 asymptomatic asthmatic subjects."5.06Comparative effects of rilmenidine and clonidine on bronchial responses to histamine in asthmatic subjects. ( Advenier, C; Dinh Xuan, AT; Lockhart, A; Matran, R; Regnard, J; Vitou, P, 1988)
"We investigated the possibility that clonidine, an alpha 2-adrenoceptor agonist, can reduce the wheal-and-flare reactions induced by intradermal injections of allergen in patients with extrinsic asthma."5.06Inhibitory effects of clonidine on the allergen-induced wheal-and-flare reactions in patients with extrinsic asthma. ( Andersson, RG; Brundin, A; Lindgren, BR, 1987)
" It has also been used intravenously in phaeochromocytoma, tetanus, clonidine withdrawal, and as an adjunct to halothane to produce hypotensive anaesthesia."4.76Combined alpha- and beta-receptor inhibition in the treatment of hypertension. ( Prichard, BN, 1984)
" Results obtained in the present study showed that EZJF and JB significantly inhibited clonidine-induced catalepsy, milk-induced leucocytosis and eosinophilia, clonidine-induced mast cell degranulation, and passive paw anaphylaxis."3.91Antiasthmatic potential of Zizyphus jujuba Mill and Jujuboside B. - Possible role in the treatment of asthma. ( Ninave, PB; Patil, SD, 2019)
" effect on clonidine and haloperidol induced catalepsy, milk-induced leucocytosis and eosinophilia, mast cell stabilizing activity in mice and studies on smooth muscle preparation of guinea pig ileum (in vitro)."3.78Antihistaminic and antiallergic actions of extracts of Solanum nigrum berries: possible role in the treatment of asthma. ( Bhawar, SB; Nirmal, SA; Patel, AP; Pattan, SR, 2012)
"To study the effect of inhaled clonidine on broncho-obstruction in asthmatics, 10 patients with extrinsic asthma were broncho-provoked twice with an allergen that had been shown to give positive skin prick test results."3.67The effect of inhaled clonidine in patients with asthma. ( Andersson, RG; Ekström, T; Lindgren, BR, 1986)
" The dose-response curves were compared by an analysis of variance."2.66Effects of clonidine on bronchial responses to histamine in normal and asthmatic subjects. ( Advenier, C; Dinh Xuan, AT; Lockhart, A; Mantrand, P; Matran, R; Regnard, J, 1988)
"Alinidine is a new bradycardic agent which has been shown to be beneficial in the treatment of coronary heart disease."2.66Safety and efficacy of alinidine in symptom-free asthmatics. ( Friedrich, T; Hoffmann, M; Huckauf, H; Kammradt, G; Lichey, J, 1986)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's4 (22.22)18.2507
2000's2 (11.11)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ninave, PB1
Patil, SD1
Nirmal, SA1
Patel, AP1
Bhawar, SB1
Pattan, SR1
Hauache, AG1
Spinola-Castro, A1
Lourenzi, V1
Tufik, S1
Naspitz, CK1
Solé, D1
Stella, MJ1
Bailey, AG1
Prichard, BN1
Kallenbach, JM1
Joffe, BI1
Seftel, HC1
Zwi, S1
Ashkenazi, S1
Mimouni, M1
Laron, Z1
Varsano, I1
Foxworth, JW1
Reisz, GR1
Pyszczynski, DR1
Knudson, SM1
Reynisdottir, S1
Wahrenberg, H1
Bylin, G1
Arner, P1
Dinh Xuan, AT4
Lockhart, A4
Matran, R3
Regnard, J3
Advenier, C3
Scott, GC1
Chu, CS1
Braun, SR1
Lindgren, BR3
Vitou, P1
Mantrand, P1
Brundin, A1
Andersson, RG2
Ekström, T1
Lichey, J1
Hoffmann, M1
Huckauf, H1
Kammradt, G1
Friedrich, T1

Reviews

3 reviews available for clonidine and Asthma, Bronchial

ArticleYear
Combined alpha- and beta-receptor inhibition in the treatment of hypertension.
    Drugs, 1984, Volume: 28 Suppl 2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Antihyp

1984
Bronchial effects of alpha 2-adrenoceptor agonists and of other antihypertensive agents in asthma.
    The American journal of medicine, 1989, Sep-18, Volume: 87, Issue:3C

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; An

1989
New aspects on the treatment of inflammatory reactions and broncho-obstruction in bronchial asthma.
    European journal of respiratory diseases. Supplement, 1987, Volume: 148

    Topics: Adrenergic alpha-Agonists; Animals; Asthma; Cattle; Clonidine; Guinea Pigs; Humans; In Vitro Techniq

1987

Trials

6 trials available for clonidine and Asthma, Bronchial

ArticleYear
Oral clonidine in patients with asthma: no significant effect on airway reactivity.
    European journal of clinical pharmacology, 1995, Volume: 48, Issue:1

    Topics: Adult; Airway Resistance; Asthma; Blood Pressure; Bronchial Hyperreactivity; Clonidine; Cross-Over S

1995
Transdermal delivery of the alpha 2-agonist clonidine does not alter airways responses to inhaled histamine or methacholine.
    Chest, 1991, Volume: 100, Issue:4

    Topics: Administration, Cutaneous; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Br

1991
Comparative effects of rilmenidine and clonidine on bronchial responses to histamine in asthmatic subjects.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Asthma; Bronchi; Clonidine; Female; Forced Expiratory Volume; Hist

1988
Effects of clonidine on bronchial responses to histamine in normal and asthmatic subjects.
    The European respiratory journal, 1988, Volume: 1, Issue:4

    Topics: Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Clonidine; Dose-Response Relationship

1988
Inhibitory effects of clonidine on the allergen-induced wheal-and-flare reactions in patients with extrinsic asthma.
    The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:6

    Topics: Allergens; Asthma; Clonidine; Histamine; Humans; Hydrocortisone; Hypersensitivity, Delayed; Hypersen

1987
Safety and efficacy of alinidine in symptom-free asthmatics.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:4

    Topics: Adult; Asthma; Blood Pressure; Cardiovascular Agents; Clonidine; Double-Blind Method; Heart Rate; Hu

1986

Other Studies

9 other studies available for clonidine and Asthma, Bronchial

ArticleYear
Antiasthmatic potential of Zizyphus jujuba Mill and Jujuboside B. - Possible role in the treatment of asthma.
    Respiratory physiology & neurobiology, 2019, Volume: 260

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Catalepsy; Clonidine; Cytokines; Disease Models, Animal; Eos

2019
Antihistaminic and antiallergic actions of extracts of Solanum nigrum berries: possible role in the treatment of asthma.
    Journal of ethnopharmacology, 2012, Jun-26, Volume: 142, Issue:1

    Topics: Animals; Anti-Allergic Agents; Asthma; Catalepsy; Clonidine; Eosinophilia; Fruit; Guinea Pigs; Halop

2012
IGF-I, IGF-BP3, and GH serum levels after stimulation tests in prepubertal allergic boys.
    Journal of investigational allergology & clinical immunology, 2003, Volume: 13, Issue:4

    Topics: Adolescent; Asthma; Body Height; Child; Clonidine; Exercise; Growth Hormone; Humans; Insulin-Like Gr

2003
Intranasal clonidine as a premedicant: three cases with unique indications.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:1

    Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Asthma; Attention Deficit Disorder with Hyper

2008
Comparison of the metabolic responses to alpha-adrenergic stimulation in asthmatics and non-asthmatics after clonidine.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Jan-28, Volume: 65, Issue:4

    Topics: Adult; Asthma; Blood Glucose; Blood Pressure; Clonidine; Female; Growth Hormone; Humans; Insulin; Ma

1984
Asthmatic attack associated with oral clonidine test.
    European journal of pediatrics, 1984, Volume: 142, Issue:3

    Topics: Asthma; Child; Clonidine; Humans; Male

1984
Effect of glucocorticosteroid treatment on beta-adrenoceptor subtype function in adipocytes from patients with asthma.
    Clinical science (London, England : 1979), 1993, Volume: 85, Issue:2

    Topics: Administration, Oral; Adult; Asthma; Cells, Cultured; Clonidine; Dobutamine; Dose-Response Relations

1993
Bronchial effects of alpha 2-adrenoceptor antagonists in asthma.
    The Journal of allergy and clinical immunology, 1991, Volume: 87, Issue:1 Pt 1

    Topics: Adrenergic alpha-Antagonists; Animals; Asthma; Clonidine; Dogs; Humans; Imidazoles; Yohimbine

1991
The effect of inhaled clonidine in patients with asthma.
    The American review of respiratory disease, 1986, Volume: 134, Issue:2

    Topics: Administration, Intranasal; Adolescent; Adult; Asthma; Clonidine; Eosinophils; Female; Forced Expira

1986