clonidine has been researched along with Anterior Choroidal Artery Infarction in 5 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When clonidine therapy was initiated, the patient responded rapidly with both subjective and objective improvements in her spasticity." | 1.28 | Clonidine in the treatment of brainstem spasticity. Case report. ( Sandford, PR; Sawasky, KB; Spengler, SE, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 1 |
| Schrader, J | 1 |
| Diener, HC | 1 |
| Lüders, S | 1 |
| Momo, K | 1 |
| Doki, K | 1 |
| Hosono, H | 1 |
| Homma, M | 1 |
| Kohda, Y | 1 |
| Afonso Pérez, E | 1 |
| Pego Reigosa, R | 1 |
| Lancho Seco, A | 1 |
| Brañas Fernández, F | 1 |
| Sandford, PR | 1 |
| Spengler, SE | 1 |
| Sawasky, KB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I-II Clinical Trial to Determine the Safety of Clonidine in Infants With Hypoxic Ischemic Encephalopathy During Therapeutic Hypothermia[NCT01862250] | Phase 1/Phase 2 | 13 participants (Actual) | Interventional | 2013-10-03 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Intravenous morphine (mg/kg) was given. The standard dose is 0.05 mg/kg per dose (NCT01862250)
Timeframe: Up to 2 days
| Intervention | mg/kg (Median) |
|---|---|
| Clonidine Infants With HIE | 0.02 |
Babies were assessed after administration of clonidine for the presence or absence of shivering. (NCT01862250)
Timeframe: 48hrs
| Intervention | Participants (Count of Participants) |
|---|---|
| Clonidine Infants With HIE | 0 |
"Trough clonidine blood levels were measured after 4-7 doses of clonidine were given intravenously with a dosing interval of every 8 hrs. Mean and standard deviation (SD) of the number of doses given prior to levels being drawn was 5.3 (mean) and 0.37 (SD).~Time after last dose before measurement was 9hrs (mean) and 2.7hrs (SD)." (NCT01862250)
Timeframe: 3 days
| Intervention | ng/ml (Median) |
|---|---|
| Clonidine Infants With HIE | 0.6 |
Following 2 hours of therapeutic hypothermia, the temperature of the thermo-blanket is adjusted up half degree per hour allowing passive rewarming until 36.5 degrees is reached (NCT01862250)
Timeframe: Beginning at 72 hours up to 12 hours
| Intervention | Hours (Median) |
|---|---|
| Clonidine Infants With HIE | 8.7 |
1 review available for clonidine and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
[Tizanidine-induced toxic hepatitis].
Topics: Aged; Cerebral Infarction; Chemical and Drug Induced Liver Injury; Clonidine; Drug Therapy, Combinat | 1999 |
4 other studies available for clonidine and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
Clonidine preconditioning decreases infarct size and improves neurological outcome from transient forebrain ischemia in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agon | 2004 |
[Treating high blood pressure in acute stroke].
Topics: Acute Disease; Adrenergic alpha-Agonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Conve | 2004 |
Drug interaction of tizanidine and fluvoxamine.
Topics: Adrenergic alpha-Agonists; Aged; Antidepressive Agents, Second-Generation; Body Temperature; Cerebra | 2004 |
Clonidine in the treatment of brainstem spasticity. Case report.
Topics: Adult; Baclofen; Cerebral Infarction; Clonidine; Female; Humans; Medulla Oblongata; Muscle Spasticit | 1992 |