clonidine has been researched along with Anankastic Personality in 30 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate noradrenergic (NE) function in obsessive-compulsive disorder (OCD), behavioral, physiological, and neuroendocrine responses to the alpha 2-adrenergic agonist clonidine were examined in 18 patients with OCD and 10 healthy subjects." | 9.07 | Noradrenergic function in obsessive-compulsive disorder: behavioral and neuroendocrine responses to clonidine and comparison to healthy controls. ( Cooper, T; DeCaria, C; Gully, R; Hollander, E; Klein, DF; Liebowitz, MR; Nitescu, A; Stover, B, 1991) |
| "In 15 patients with obsessive-compulsive disorder (OCD) and in 15 healthy controls postsynaptic alpha-2-adrenoceptor sensitivity was examined by measuring the growth hormone (GH) response to growth hormone-releasing hormone (GHRH) and to clonidine stimulation." | 7.69 | Noradrenergic receptor sensitivity in obsessive-compulsive disorders: I. Growth hormone response to clonidine stimulation. ( Arancio, C; Bellodi, L; Bertani, A; Brambilla, F; Carraro, C; Gava, F; Perini, G; Perna, G, 1997) |
| "Clonazepam improvement was unrelated to changes in anxiety and occurred early in treatment." | 6.67 | Clomipramine, clonazepam, and clonidine treatment of obsessive-compulsive disorder. ( Agras, WS; Hewlett, WA; Vinogradov, S, 1992) |
| "To evaluate noradrenergic (NE) function in obsessive-compulsive disorder (OCD), behavioral, physiological, and neuroendocrine responses to the alpha 2-adrenergic agonist clonidine were examined in 18 patients with OCD and 10 healthy subjects." | 5.07 | Noradrenergic function in obsessive-compulsive disorder: behavioral and neuroendocrine responses to clonidine and comparison to healthy controls. ( Cooper, T; DeCaria, C; Gully, R; Hollander, E; Klein, DF; Liebowitz, MR; Nitescu, A; Stover, B, 1991) |
| " The study aimed to determine the risk of TBI in TS patients, the effects associated with concurrent psychiatric disorders (attention-deficit/hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), or depressive disorder), and the effects of medication treatment (antipsychotics, antidepressants, or clonidine) on the risk of TBI." | 3.91 | Tourette's syndrome is associated with an increased risk of traumatic brain injury: A nationwide population-based cohort study. ( Chen, SF; Hsu, CY; Shen, YC; Su, YC; Wang, LY, 2019) |
| " We now report that these OCD-like mice, like humans, also exhibit comorbid TS-like behaviors, including juvenile-onset tics; increased tic number, complexity and flurries; increased tic severity in males; voluntary tic suppression; and tic responsiveness to a non-cataleptic TS+OCD drug therapy (clonidine, 0." | 3.71 | A transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder circuitry. ( Burton, FH; Nordstrom, EJ, 2002) |
| "In 15 patients with obsessive-compulsive disorder (OCD) and in 15 healthy controls postsynaptic alpha-2-adrenoceptor sensitivity was examined by measuring the growth hormone (GH) response to growth hormone-releasing hormone (GHRH) and to clonidine stimulation." | 3.69 | Noradrenergic receptor sensitivity in obsessive-compulsive disorders: I. Growth hormone response to clonidine stimulation. ( Arancio, C; Bellodi, L; Bertani, A; Brambilla, F; Carraro, C; Gava, F; Perini, G; Perna, G, 1997) |
| "Sensitivity of pre-synaptic alpha-2- and post-synaptic alpha-1- and beta-adrenoceptors was investigated in 15 patients with obsessive-compulsive disorder (OCD) and in 15 age- and sex-matched healthy controls, by measuring cortisol responses to saline administration and to inhibition by clonidine (clon), a noradrenergic receptor agonist." | 3.69 | Noradrenergic receptor sensitivity in obsessive compulsive disorder: II. Cortisol response to acute clonidine administration. ( Arancio, C; Bellodi, L; Bertani, A; Brambilla, F; Carraro, C; Gava, F; Perini, G; Perna, G, 1997) |
| "Ten patients with obsessive-compulsive disorder (OCD) and 13 normal control subjects received intravenous infusions of 2 X 10(-6) g/kg of clonidine and normal saline on separate days." | 3.68 | Alpha 2-adrenoreceptor status in obsessive-compulsive disorder. ( Abelson, JL; Cameron, OG; Curtis, GC; Glitz, D; Gurguis, GN; Hariharan, M; Lee, MA; Smith, CB, 1990) |
| "We have observed a lesser growth hormone response to intravenous clonidine administration in nine obsessive-compulsive disorder patients meeting research diagnostic criteria than in nine matched controls." | 3.66 | Growth hormone response to clonidine in obsessive-compulsive patients. ( Aloi, J; Insel, TR; Jimerson, DC; Lake, CR; Murphy, DL; Siever, LJ; Uhde, TW, 1983) |
| "Clonazepam improvement was unrelated to changes in anxiety and occurred early in treatment." | 2.67 | Clomipramine, clonazepam, and clonidine treatment of obsessive-compulsive disorder. ( Agras, WS; Hewlett, WA; Vinogradov, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (36.67) | 18.7374 |
| 1990's | 10 (33.33) | 18.2507 |
| 2000's | 6 (20.00) | 29.6817 |
| 2010's | 3 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jain, S | 1 |
| Gupta, T | 1 |
| Nebhinani, N | 1 |
| Singhai, K | 1 |
| Suthar, N | 1 |
| Chen, SF | 1 |
| Su, YC | 1 |
| Wang, LY | 1 |
| Hsu, CY | 1 |
| Shen, YC | 1 |
| Rickards, H | 1 |
| Cavanna, AE | 1 |
| Worrall, R | 1 |
| Nordstrom, EJ | 1 |
| Burton, FH | 1 |
| Suchard, JR | 1 |
| Graeme, KA | 1 |
| Listernick, R | 1 |
| Kano, Y | 1 |
| Kotcher, L | 1 |
| Wieland, N | 2 |
| Coffey, B | 2 |
| Leckman, JF | 1 |
| Cohen, DJ | 2 |
| Insel, TR | 4 |
| Mueller, EA | 1 |
| Gillin, JC | 1 |
| Siever, LJ | 4 |
| Murphy, DL | 5 |
| Jimerson, DC | 2 |
| Lake, CR | 2 |
| Uhde, TW | 2 |
| Aloi, J | 2 |
| Knesevich, JW | 1 |
| Ahsanuddin, K | 1 |
| Campbell, M | 1 |
| Cueva, JE | 1 |
| Como, PG | 1 |
| Singer, HS | 1 |
| Brambilla, F | 2 |
| Perna, G | 2 |
| Bellodi, L | 2 |
| Arancio, C | 2 |
| Bertani, A | 2 |
| Perini, G | 2 |
| Carraro, C | 2 |
| Gava, F | 2 |
| Peterson, BS | 1 |
| Hewlett, WA | 1 |
| Vinogradov, S | 1 |
| Agras, WS | 1 |
| Hollander, E | 3 |
| DeCaria, C | 1 |
| Nitescu, A | 1 |
| Cooper, T | 1 |
| Stover, B | 1 |
| Gully, R | 1 |
| Klein, DF | 1 |
| Liebowitz, MR | 3 |
| Bihari, K | 1 |
| Pato, MT | 1 |
| Hill, JL | 1 |
| Lee, MA | 1 |
| Cameron, OG | 1 |
| Gurguis, GN | 1 |
| Glitz, D | 1 |
| Smith, CB | 1 |
| Hariharan, M | 1 |
| Abelson, JL | 1 |
| Curtis, GC | 1 |
| Fay, M | 2 |
| Cohen, B | 1 |
| Campeas, R | 1 |
| Gorman, JM | 1 |
| Kaye, WH | 1 |
| Kafka, M | 1 |
| Targum, S | 1 |
| Caine, ED | 1 |
| McBride, MC | 1 |
| Chiverton, P | 1 |
| Bamford, KA | 1 |
| Rediess, S | 1 |
| Shiao, J | 1 |
| Lipsedge, MS | 1 |
| Prothero, W | 1 |
| Hamilton, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00004325] | 200 participants | Observational | 1988-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for clonidine and Anankastic Personality
| Article | Year |
|---|---|
[Chronic tic disorders--chronic mortor or vocal tic disorders and de la Tourette's syndrome].
Topics: Adolescent; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sy | 2003 |
Recent advances in Gilles de la Tourette syndrome: implications for clinical practice and future research.
Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Compulsive | 1983 |
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder | 1995 |
Obsessive-compulsive disorder in Tourette's syndrome.
Topics: Behavior Therapy; Clomipramine; Clonidine; Fluvoxamine; Humans; Obsessive-Compulsive Disorder; Toure | 1995 |
Tic disorders.
Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Child; Child | 1993 |
The treatment of Tourette's syndrome: multimodal, developmental intervention.
Topics: Adaptation, Psychological; Adolescent; Adrenergic Agonists; Adult; Age Factors; Antidepressive Agent | 1998 |
4 trials available for clonidine and Anankastic Personality
| Article | Year |
|---|---|
Clomipramine, clonazepam, and clonidine treatment of obsessive-compulsive disorder.
Topics: Adult; Analysis of Variance; Anxiety; Clomipramine; Clonazepam; Clonidine; Depression; Double-Blind | 1992 |
Noradrenergic function in obsessive-compulsive disorder: behavioral and neuroendocrine responses to clonidine and comparison to healthy controls.
Topics: Adolescent; Adult; Affect; Anxiety; Behavior; Clonidine; Growth Hormone; Humans; Hydrocortisone; Met | 1991 |
Serotonergic and noradrenergic sensitivity in obsessive-compulsive disorder: behavioral findings.
Topics: Adult; Clonidine; Fenfluramine; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Piperazine | 1988 |
Clonidine and clomipramine in obsessive-compulsive disorder.
Topics: Administration, Oral; Clinical Trials as Topic; Clomipramine; Clonidine; Double-Blind Method; Drug T | 1988 |
20 other studies available for clonidine and Anankastic Personality
| Article | Year |
|---|---|
Therapeutic challenges in comorbid obsessive compulsive disorder with substance use.
Topics: Adrenergic alpha-2 Receptor Agonists; Clonazepam; Clonidine; Combined Modality Therapy; Fluoxetine; | 2018 |
Tourette's syndrome is associated with an increased risk of traumatic brain injury: A nationwide population-based cohort study.
Topics: Adolescent; Adult; Antidepressive Agents; Antipsychotic Agents; Attention Deficit Disorder with Hype | 2019 |
Treatment practices in Tourette syndrome: the European perspective.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety; Aripiprazole; Atomoxetine Hydrochloride | 2012 |
A transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder circuitry.
Topics: Analgesics; Animals; Cholera Toxin; Clonidine; Comorbidity; Female; Incidence; Male; Mice; Mice, Tra | 2002 |
Pediatric clonidine poisoning as a result of pharmacy compounding error.
Topics: Adrenergic alpha-Agonists; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Drug Com | 2002 |
A nine-year-old girl with new-onset tics.
Topics: Antipsychotic Agents; Child; Chorea; Clonidine; Diagnosis, Differential; Female; Humans; Obsessive-C | 2003 |
Trichotillomania and co-morbid psychiatric disorders in a 10-year-old boy.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Comorbidity; Drug Therapy, Combinat | 2007 |
Tics, anxiety, and possible PANDAS in an adolescent.
Topics: Adolescent; Adrenergic alpha-Agonists; Antidepressive Agents, Second-Generation; Anxiety; Autoimmune | 2007 |
Biological markers in obsessive-compulsive and affective disorders.
Topics: Blood Platelets; Clomipramine; Clonidine; Depressive Disorder; Dexamethasone; Electroencephalography | 1984 |
Growth hormone response to clonidine in obsessive-compulsive patients.
Topics: Adolescent; Adult; Clonidine; Female; Growth Hormone; Humans; Male; Methoxyhydroxyphenylglycol; Midd | 1983 |
Successful treatment of obsessive-compulsive disorder with clonidine hydrochloride.
Topics: Adult; Clonidine; Drug Administration Schedule; Female; Humans; Obsessive-Compulsive Disorder | 1982 |
Side effects of clonidine.
Topics: Affective Disorders, Psychotic; Bipolar Disorder; Clonidine; Delusions; Humans; Obsessive-Compulsive | 1982 |
Noradrenergic receptor sensitivity in obsessive-compulsive disorders: I. Growth hormone response to clonidine stimulation.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Clonidine; Female; Growth Hormone-Releasing Hormone; H | 1997 |
Noradrenergic receptor sensitivity in obsessive compulsive disorder: II. Cortisol response to acute clonidine administration.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Clonidine; Female; Humans; Hydrocortisone; Male; Middl | 1997 |
Neurologic soft signs in obsessive-compulsive disorder.
Topics: Adult; Anxiety Disorders; Central Nervous System Diseases; Clomipramine; Clonidine; Depressive Disor | 1991 |
Alpha 2-adrenoreceptor status in obsessive-compulsive disorder.
Topics: Adult; Arousal; Blood Platelets; Brain; Clonidine; Female; Glycols; Growth Hormone; Humans; Male; Me | 1990 |
Biological alterations in the primary affective disorders and other tricyclic-responsive disorders.
Topics: Adult; Agoraphobia; Anorexia Nervosa; Clonidine; Cyclic AMP; Depressive Disorder; Dihydroergotoxine; | 1985 |
Tourette's syndrome in Monroe County school children.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Behavior; Child; Child, Preschool; Clonid | 1988 |
Clonidine and clomipramine in obsessive-compulsive disorder.
Topics: Adolescent; Adult; Clomipramine; Clonidine; Drug Therapy, Combination; Female; Humans; Male; Obsessi | 1987 |
A comparison between the growth hormone responses to amphetamine and clonidine.
Topics: Adult; Amphetamine; Clonidine; Depressive Disorder; Growth Hormone; Humans; Obsessive-Compulsive Dis | 1985 |