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clonidine and Alcohol Amnestic Disorder

clonidine has been researched along with Alcohol Amnestic Disorder in 12 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Alcohol Amnestic Disorder: A mental disorder associated with chronic ethanol abuse (ALCOHOLISM) and nutritional deficiencies characterized by short term memory loss, confabulations, and disturbances of attention. (Adams et al., Principles of Neurology, 6th ed, p1139)

Research Excerpts

ExcerptRelevanceReference
"Seven normotensive patients with alcohol amnestic disorder were treated with 2 micrograms/kg clonidine (C) three times daily for 1 wk."7.66Urinary catecholamine metabolites and effects of clonidine in patients with alcohol amnestic disorder. ( Ebert, MH; Gordon, EK; Kopin, IJ; Martin, PR, 1983)
"Clonidine treatment resulted in no significant improvement over placebo on any of the cognitive measures employed."2.67Korsakoff's syndrome, cognition and clonidine. ( Ebmeier, KP; Goodwin, GM; Moffoot, A; Murray, C; O'Carroll, RE, 1993)
"Patients with Korsakoff's disease, attention deficit disorder or schizophrenia may benefit from treatment with alpha 2-agents."2.39Pharmacological manipulations of the alpha 2-noradrenergic system. Effects on cognition. ( Coull, JT, 1994)
"Treatment with clonidine resulted in a significant improvement in spatial delayed alteration for experimental as compared to control animals."1.27Learning impairments after 6-OHDA treatment: a comparison with the effects of thiamine deficiency. ( Anderson, CD; Langlais, PJ; Mair, RG; McEntee, WJ, 1986)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's4 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johnson, JM1
McEntee, WJ4
Mair, RG5
Langlais, PJ2
Martin, PR1
Ebert, MH1
Gordon, EK1
Kopin, IJ1
Coull, JT1
Moffoot, A2
O'Carroll, RE2
Murray, C2
Dougall, N1
Ebmeier, K1
Goodwin, GM2
Ebmeier, KP1
McEntee, MJ1
Larner, AJ1
Anderson, CD1
Rozniecki, J1

Reviews

2 reviews available for clonidine and Alcohol Amnestic Disorder

ArticleYear
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic;

1984
Pharmacological manipulations of the alpha 2-noradrenergic system. Effects on cognition.
    Drugs & aging, 1994, Volume: 5, Issue:2

    Topics: Aging; Alcohol Amnestic Disorder; Animals; Attention Deficit Disorder with Hyperactivity; Brain; Clo

1994

Trials

5 trials available for clonidine and Alcohol Amnestic Disorder

ArticleYear
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic;

1984
Memory enhancement in Korsakoff's psychosis by clonidine: further evidence for a noradrenergic deficit.
    Annals of neurology, 1980, Volume: 7, Issue:5

    Topics: Adult; Alcohol Amnestic Disorder; Clinical Trials as Topic; Clonidine; Dextroamphetamine; Double-Bli

1980
Clonidine infusion increases uptake of 99mTc-Exametazime in anterior cingulate cortex in Korsakoff's psychosis.
    Psychological medicine, 1994, Volume: 24, Issue:1

    Topics: Adult; Aged; Alcohol Amnestic Disorder; Cerebrovascular Circulation; Clonidine; Cognition Disorders;

1994
Korsakoff's syndrome, cognition and clonidine.
    Psychological medicine, 1993, Volume: 23, Issue:2

    Topics: Aged; Alcohol Amnestic Disorder; Attention; Clonidine; Double-Blind Method; Female; Frontal Lobe; Hu

1993
Cognitive enhancement in Korsakoff's psychosis by clonidine: a comparison with L-dopa and ephedrine.
    Psychopharmacology, 1986, Volume: 88, Issue:3

    Topics: Alcohol Amnestic Disorder; Attention; Biogenic Amines; Brain Chemistry; Clonidine; Cognition Disorde

1986

Other Studies

6 other studies available for clonidine and Alcohol Amnestic Disorder

ArticleYear
Clonidine in Korsakoff disease: pathophysiologic and therapeutic implications.
    Progress in clinical and biological research, 1981, Volume: 71

    Topics: Alcohol Amnestic Disorder; Animals; Brain; Clonidine; Dextroamphetamine; Humans; Hydroxyindoleacetic

1981
Urinary catecholamine metabolites and effects of clonidine in patients with alcohol amnestic disorder.
    Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:1

    Topics: Aged; Alcohol Amnestic Disorder; Blood Pressure; Catecholamines; Clonidine; Dose-Response Relationsh

1983
Central monoamine activity in Korsakoff's psychosis.
    Transactions of the American Neurological Association, 1978, Volume: 103

    Topics: Alcohol Amnestic Disorder; Clonidine; Dextroamphetamine; Humans; Methysergide

1978
Further evidence of the versatility of clonidine.
    British journal of hospital medicine, 1991, Volume: 45, Issue:4

    Topics: Alcohol Amnestic Disorder; Clonidine; Heroin Dependence; Humans

1991
Learning impairments after 6-OHDA treatment: a comparison with the effects of thiamine deficiency.
    Behavioural brain research, 1986, Volume: 21, Issue:1

    Topics: Alcohol Amnestic Disorder; Animals; Avoidance Learning; Brain Chemistry; Catecholamines; Clonidine;

1986
[Less known indications for the use of clonidine].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1985, Feb-15, Volume: 38, Issue:4

    Topics: Alcohol Amnestic Disorder; Brain Diseases; Clonidine; Glaucoma; Humans; Migraine Disorders; Opioid-R

1985