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clonidine and Agoraphobia

clonidine has been researched along with Agoraphobia in 11 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Agoraphobia: Obsessive, persistent, intense fear of open places.

Research Excerpts

ExcerptRelevanceReference
") and to clonidine (150 micrograms) were measured in 10 outpatients with panic disorder before and after 30 days of 2-2."9.08Alpha 2-adrenergic receptor sensitivity in panic disorder: I. GH response to GHRH and clonidine stimulation in panic disorder. ( Bellodi, L; Brambilla, F; Garberi, A; Nobile, P; Perna, G, 1995)
"The cortisol responses to acute administration of saline and of clonidine (Clon), 150 micrograms IV, were examined in 12 patients with panic disorder and agoraphobia, before and after 32 days of alprazolam therapy (2."9.08Alpha 2-adrenergic receptor sensitivity in panic disorder: II. Cortisol response to clonidine stimulation in panic disorder. ( Arancio, C; Bellodi, L; Brambilla, F; Nobile, P; Perna, G, 1995)
"Clonidine hydrochloride, an alpha 2-adrenergic receptor agonist that decreases noradrenergic function, was administered to 21 healthy subjects and 26 drug-free patients with agoraphobia and panic attacks."9.06Abnormal regulation of noradrenergic function in panic disorders. Effects of clonidine in healthy subjects and patients with agoraphobia and panic disorder. ( Charney, DS; Heninger, GR, 1986)
") and to clonidine (150 micrograms) were measured in 10 outpatients with panic disorder before and after 30 days of 2-2."5.08Alpha 2-adrenergic receptor sensitivity in panic disorder: I. GH response to GHRH and clonidine stimulation in panic disorder. ( Bellodi, L; Brambilla, F; Garberi, A; Nobile, P; Perna, G, 1995)
"The cortisol responses to acute administration of saline and of clonidine (Clon), 150 micrograms IV, were examined in 12 patients with panic disorder and agoraphobia, before and after 32 days of alprazolam therapy (2."5.08Alpha 2-adrenergic receptor sensitivity in panic disorder: II. Cortisol response to clonidine stimulation in panic disorder. ( Arancio, C; Bellodi, L; Brambilla, F; Nobile, P; Perna, G, 1995)
"Clonidine hydrochloride, an alpha 2-adrenergic receptor agonist that decreases noradrenergic function, was administered to 21 healthy subjects and 26 drug-free patients with agoraphobia and panic attacks."5.06Abnormal regulation of noradrenergic function in panic disorders. Effects of clonidine in healthy subjects and patients with agoraphobia and panic disorder. ( Charney, DS; Heninger, GR, 1986)
" Among the more important recent discoveries are the efficacy of the tricyclic antidepressants for panic disorder and agoraphobia with panic attacks; the use of the monoamine oxidase inhibitors for the above disorders and for atypical depression and hysteroid dysphoria; the use of propranolol for anxiety disorders and for uncontrollable violent outbursts; the antianxiety and antipanic effects of clonidine; and the usefulness of lithium in treating schizophrenia and schizoaffective disorder and for emotionally unstable character disorders."4.76Newer uses for older psychotropic medications. ( Liebowitz, MR, 1982)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's3 (27.27)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liebowitz, MR3
Zelnik, TC1
Garcia-Sevilla, JA1
Cameron, OG2
Smith, CB2
Fyer, AJ2
Gorman, JM2
Dillon, D2
Appleby, IL1
Levy, G1
Anderson, S1
Levitt, M1
Palij, M1
Davies, SO1
Brambilla, F2
Perna, G2
Garberi, A1
Nobile, P2
Bellodi, L2
Arancio, C1
Lee, MA1
Hollingsworth, PJ1
Hill, EM1
Curtis, GC1
Stein, MB1
Uhde, TW3
Siever, LJ2
Insel, TR1
Kaye, WH2
Jimerson, DC1
Lake, CR1
Kafka, M1
Targum, S1
Murphy, DL1
Charney, DS1
Heninger, GR1
Cohen, BS1
Klein, DF1
Vittone, BJ1
Post, RM1

Reviews

1 review available for clonidine and Agoraphobia

ArticleYear
Newer uses for older psychotropic medications.
    Hospital & community psychiatry, 1982, Volume: 33, Issue:4

    Topics: Adrenergic beta-Antagonists; Agoraphobia; Anxiety Disorders; Bipolar Disorder; Clonidine; Depressive

1982

Trials

3 trials available for clonidine and Agoraphobia

ArticleYear
Alpha 2-adrenergic receptor sensitivity in panic disorder: I. GH response to GHRH and clonidine stimulation in panic disorder.
    Psychoneuroendocrinology, 1995, Volume: 20, Issue:1

    Topics: Adult; Agoraphobia; Alprazolam; Clonidine; Female; Growth Hormone; Growth Hormone-Releasing Hormone;

1995
Alpha 2-adrenergic receptor sensitivity in panic disorder: II. Cortisol response to clonidine stimulation in panic disorder.
    Psychoneuroendocrinology, 1995, Volume: 20, Issue:1

    Topics: Adult; Agoraphobia; Alprazolam; Clonidine; Female; Humans; Hydrocortisone; Male; Middle Aged; Panic

1995
Abnormal regulation of noradrenergic function in panic disorders. Effects of clonidine in healthy subjects and patients with agoraphobia and panic disorder.
    Archives of general psychiatry, 1986, Volume: 43, Issue:11

    Topics: Adult; Agoraphobia; Anxiety Disorders; Blood Pressure; Clonidine; Fear; Female; Growth Hormone; Huma

1986

Other Studies

7 other studies available for clonidine and Agoraphobia

ArticleYear
Clinical response to clonidine and imipramine, and platelet alpha 2-adrenoreceptors in a case of agoraphobia with panic attacks.
    Biological psychiatry, 1982, Volume: 17, Issue:6

    Topics: Adult; Agoraphobia; Blood Platelets; Clonidine; Drug Therapy, Combination; Fear; Humans; Imipramine;

1982
Lactate provocation of panic attacks. I. Clinical and behavioral findings.
    Archives of general psychiatry, 1984, Volume: 41, Issue:8

    Topics: Adult; Agoraphobia; Anxiety Disorders; Clonidine; Desipramine; Fear; Female; Humans; Imipramine; Lac

1984
Adrenergic status in anxiety disorders: platelet alpha 2-adrenergic receptor binding, blood pressure, pulse, and plasma catecholamines in panic and generalized anxiety disorder patients and in normal subjects.
    Biological psychiatry, 1990, Jul-01, Volume: 28, Issue:1

    Topics: Adult; Agoraphobia; Anxiety Disorders; Arousal; Blood Platelets; Blood Pressure; Clonidine; Epinephr

1990
Cortisol response to clonidine in panic disorder: comparison with depressed patients and normal controls.
    Biological psychiatry, 1988, Volume: 24, Issue:3

    Topics: Adult; Agoraphobia; Bipolar Disorder; Clonidine; Depressive Disorder; Fear; Female; Humans; Hydrocor

1988
Biological alterations in the primary affective disorders and other tricyclic-responsive disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:1

    Topics: Adult; Agoraphobia; Anorexia Nervosa; Clonidine; Cyclic AMP; Depressive Disorder; Dihydroergotoxine;

1985
Antipanic drug effects during lactate infusion in lactate-refractory panic patients.
    Psychiatry research, 1987, Volume: 21, Issue:3

    Topics: Adult; Agoraphobia; Alprazolam; Clonidine; Desipramine; Fear; Female; Fluoxetine; Humans; Imipramine

1987
Blunted growth hormone response to clonidine in panic disorder patients.
    Biological psychiatry, 1986, Volume: 21, Issue:11

    Topics: Adrenergic Fibers; Adult; Agoraphobia; Antidepressive Agents, Tricyclic; Anxiety Disorders; Brain; C

1986