clonidine has been researched along with Age-Related Memory Disorders in 18 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current pharmacotherapies for PTSD manage only a subset of these symptoms and typically have adverse side effects which limit their overall effectiveness." | 5.39 | Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD. ( Diamond, DM; Fleshner, M; Zoladz, PR, 2013) |
| "Sub-acute brain ischemia is a risk factor for the development of vascular dementia (VaD)." | 1.40 | Pharmacological modulation of I(1)-imidazoline and α2-adrenoceptors in sub acute brain ischemia induced vascular dementia. ( Gupta, S; Sharma, B, 2014) |
| "Current pharmacotherapies for PTSD manage only a subset of these symptoms and typically have adverse side effects which limit their overall effectiveness." | 1.39 | Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD. ( Diamond, DM; Fleshner, M; Zoladz, PR, 2013) |
| "Additionally, only reboxetine reduced memory deficits in the MWM." | 1.38 | Morris water maze performance deficit produced by intermittent swim stress is partially mediated by norepinephrine. ( Drugan, RC; Warner, TA, 2012) |
| "Clonidine pretreatment significantly alleviated these drug-induced deficits." | 1.35 | The effects of clonidine on discrete-trial delayed spatial alternation in two rat models of memory loss. ( Bardgett, ME; Griffith, MS; Lamontagne, T; McDaniel, T; Points, M; Ramsey-Faulkner, C; Roflow, J; Topmiller, J, 2008) |
| "Clonidine pretreatment (0." | 1.31 | Noradrenergic alpha-2 receptor agonists reverse working memory deficits induced by the anxiogenic drug, FG7142, in rats. ( Arnsten, AF; Birnbaum, SG; Podell, DM, 2000) |
| "Memory deficits were induced by the muscarinic cholinoceptor antagonist scopolamine (in young and old rats and mice), by the alpha 2-adrenoceptor agonist clonidine, by electroconvulsive shock, and by hypoxy." | 1.29 | Effects of cytidine diphosphate choline on rats with memory deficits. ( Getova, D; Kehayov, RA; Lazarova, MB; Mosharrof, AH; Petkov, VD; Petkov, VV; Vaglenova, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Sang, Z | 2 |
| Pan, W | 1 |
| Wang, K | 2 |
| Ma, Q | 1 |
| Yu, L | 1 |
| Yang, Y | 1 |
| Bai, P | 2 |
| Leng, C | 1 |
| Xu, Q | 1 |
| Li, X | 1 |
| Tan, Z | 1 |
| Liu, W | 1 |
| Zhang, P | 1 |
| Shi, J | 1 |
| Cheng, X | 1 |
| Zhang, Q | 1 |
| Zheng, C | 1 |
| Cheng, Y | 1 |
| Yang, J | 1 |
| Lu, X | 1 |
| Marin, FN | 1 |
| Franzen, JM | 1 |
| Troyner, F | 1 |
| Molina, VA | 1 |
| Giachero, M | 1 |
| Bertoglio, LJ | 1 |
| Jafari-Sabet, M | 1 |
| Banafshe, HR | 1 |
| Khodadadnejad, MA | 1 |
| Gupta, S | 1 |
| Sharma, B | 1 |
| Norozpour, Y | 1 |
| Nasehi, M | 2 |
| Sabouri-Khanghah, V | 1 |
| Torabi-Nami, M | 1 |
| Zarrindast, MR | 2 |
| Beiranvand, A | 1 |
| Moghaddasi, M | 1 |
| Warner, TA | 1 |
| Drugan, RC | 1 |
| Zoladz, PR | 1 |
| Fleshner, M | 1 |
| Diamond, DM | 1 |
| Collier, TJ | 1 |
| Greene, JG | 1 |
| Felten, DL | 1 |
| Stevens, SY | 1 |
| Collier, KS | 1 |
| Jentsch, JD | 2 |
| Anzivino, LA | 1 |
| Marrs, W | 1 |
| Kuperman, J | 1 |
| Avedian, T | 1 |
| Roth, RH | 1 |
| Bardgett, ME | 1 |
| Points, M | 1 |
| Ramsey-Faulkner, C | 1 |
| Topmiller, J | 1 |
| Roflow, J | 1 |
| McDaniel, T | 1 |
| Lamontagne, T | 1 |
| Griffith, MS | 1 |
| Petkov, VD | 3 |
| Kehayov, RA | 1 |
| Mosharrof, AH | 1 |
| Petkov, VV | 1 |
| Getova, D | 1 |
| Lazarova, MB | 2 |
| Vaglenova, J | 1 |
| Birnbaum, SG | 1 |
| Podell, DM | 1 |
| Arnsten, AF | 1 |
| Lazarova-Bakarova, MB | 1 |
| Petkova, BP | 1 |
| Todorov, IK | 1 |
| Voronina, TA | 1 |
| Garibova, TL | 1 |
| Trofimov, SS | 1 |
| Sopyev, ZhA | 1 |
| Fein, G | 1 |
| Merrin, EL | 1 |
| Davenport, L | 1 |
| Buffum, JC | 1 |
18 other studies available for clonidine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholine | 2017 |
Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Biological Tr | 2019 |
Taking advantage of fear generalization-associated destabilization to attenuate the underlying memory via reconsolidation intervention.
Topics: Adrenergic alpha-Agonists; Animals; CA1 Region, Hippocampal; Clonidine; Early Growth Response Protei | 2020 |
Modulation of muscimol state-dependent memory by α2-adrenoceptors of the dorsal hippocampal area.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Avoidance Le | 2013 |
Pharmacological modulation of I(1)-imidazoline and α2-adrenoceptors in sub acute brain ischemia induced vascular dementia.
Topics: Acetylcholinesterase; Adrenergic alpha-2 Receptor Agonists; Animals; Brain; Brain Ischemia; Catalase | 2014 |
The effect of CA1 α2 adrenergic receptors on memory retention deficit induced by total sleep deprivation and the reversal of circadian rhythm in a rat model.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Behavior, An | 2016 |
Involvement of medial prefrontal cortex alpha-2 adrenoceptors on memory acquisition deficit induced by arachidonylcyclopropylamide, a cannabinoid CB1 receptor agonist, in rats; possible involvement of Ca2+ channels.
Topics: Amnesia; Animals; Arachidonic Acids; Calcium Channels; Clonidine; Dose-Response Relationship, Drug; | 2016 |
Morris water maze performance deficit produced by intermittent swim stress is partially mediated by norepinephrine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Analy | 2012 |
Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD.
Topics: Adrenocorticotropic Hormone; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antihypertens | 2013 |
Reduced cortical noradrenergic neurotransmission is associated with increased neophobia and impaired spatial memory in aged rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals | 2004 |
A low dose of the alpha2 agonist clonidine ameliorates the visual attention and spatial working memory deficits produced by phencyclidine administration to rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Attention; Clonidine; Dose-Response Relationship, Dru | 2004 |
Alpha-2 adrenoceptor activation inhibits phencyclidine-induced deficits of spatial working memory in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analy | 2005 |
The effects of clonidine on discrete-trial delayed spatial alternation in two rat models of memory loss.
Topics: Adrenergic alpha-Agonists; Animals; Attention; Clonidine; Dizocilpine Maleate; Excitatory Amino Acid | 2008 |
Effects of cytidine diphosphate choline on rats with memory deficits.
Topics: Aging; Animals; Avoidance Learning; Clonidine; Cytidine Diphosphate Choline; Electroshock; Fetal Alc | 1993 |
Noradrenergic alpha-2 receptor agonists reverse working memory deficits induced by the anxiogenic drug, FG7142, in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Carbolines; Clonidine; GAB | 2000 |
Memory impairment induced by combined disturbance of noradrenergic and dopaminergic neurotransmissions: effects of nootropic drugs.
Topics: Animals; Avoidance Learning; Benzoates; Central Nervous System Agents; Clonidine; Dopamine; Haloperi | 1991 |
Comparative studies on the influence of ONK (N(5-hydroxynicotinoil) glutamic acid), piracetam and meclofenoxate on the learning- and memory-impairing effect of scopolamine, clonidine, and methergoline.
Topics: Animals; Avoidance Learning; Clonidine; Glutamates; Learning Disabilities; Male; Meclofenoxate; Memo | 1991 |
Memory deficits associated with clonidine.
Topics: Aged; Clonidine; Humans; Male; Memory Disorders; Neuropsychological Tests | 1987 |