clonidine has been researched along with Adjuvant Arthritis in 4 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonidine was found to be highly effective in arthritic animals, even at the lower concentration: the elevation in threshold produced by 30 micrograms/kg i." | 5.28 | Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat. ( Besson, JM; Guilbaud, G; Kayser, V, 1992) |
| " α1 (phenylephrine), α2 (clonidine), β1 (dobutamine), or β2 (salbutamol)-adrenoceptor agonists were injected subcutaneously (sc), intrathecally (it), or intra-articularly (ia) to activate peripheral, spinal, or intra-articular adrenoceptors and to study their effects on articular edema formation and neutrophil migration into the synovial cavity." | 3.91 | Regulation of murine arthritis by systemic, spinal, and intra-articular adrenoceptors. ( Alves, HR; Bassi, GS; Cunha, FQ; Dutra, SGV; Kanashiro, A; Leoncio, TOL; Malvar, DDC; Schneider, AH; Ulloa, L, 2019) |
| "Apraclonidine was given intraperitoneally 2--3 days after CFA injection." | 1.31 | Apraclonidine attenuates the increases in spinal excitatory amino acid release in rats with adjuvant-induced inflammation. ( Buerkle, H; Lin, CR; Wang, CH; Wen, ZH; Wu, P; Yang, LC, 2002) |
| "Clonidine was found to be highly effective in arthritic animals, even at the lower concentration: the elevation in threshold produced by 30 micrograms/kg i." | 1.28 | Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat. ( Besson, JM; Guilbaud, G; Kayser, V, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kanashiro, A | 1 |
| Leoncio, TOL | 1 |
| Schneider, AH | 1 |
| Alves, HR | 1 |
| Bassi, GS | 1 |
| Dutra, SGV | 1 |
| Cunha, FQ | 1 |
| Ulloa, L | 1 |
| Malvar, DDC | 1 |
| Miura, T | 1 |
| Okazaki, R | 1 |
| Yoshida, H | 1 |
| Namba, H | 1 |
| Okai, H | 1 |
| Kawamura, M | 1 |
| Lin, CR | 1 |
| Wang, CH | 1 |
| Wu, P | 1 |
| Wen, ZH | 1 |
| Buerkle, H | 1 |
| Yang, LC | 1 |
| Kayser, V | 1 |
| Guilbaud, G | 1 |
| Besson, JM | 1 |
4 other studies available for clonidine and Adjuvant Arthritis
| Article | Year |
|---|---|
Regulation of murine arthritis by systemic, spinal, and intra-articular adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Arthritis, Experimental; Ce | 2019 |
Mechanisms of analgesic action of neurotropin on chronic pain in adjuvant-induced arthritic rat: roles of descending noradrenergic and serotonergic systems.
Topics: Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analges | 2005 |
Apraclonidine attenuates the increases in spinal excitatory amino acid release in rats with adjuvant-induced inflammation.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Arthritis, Experimental; C | 2002 |
Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat.
Topics: Adrenergic beta-Antagonists; Analgesics; Analysis of Variance; Animals; Arthritis, Experimental; Clo | 1992 |