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clonidine and Acute Liver Injury, Drug-Induced

clonidine has been researched along with Acute Liver Injury, Drug-Induced in 10 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Research Excerpts

ExcerptRelevanceReference
"Hepatic necrosis produced by carbon tetrachloride (0."3.68Potentiation of carbon tetrachloride hepatotoxicity by phenylpropanolamine. ( Harbison, RD; James, RC; Roberts, SM; Seng, JE, 1991)
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts."1.37FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's4 (40.00)18.2507
2000's0 (0.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Chen, M2
Vijay, V1
Shi, Q2
Liu, Z2
Fang, H2
Tong, W3
Ding, D1
Kelly, R1
Xie, SS1
Lan, JS1
Wang, XB1
Jiang, N1
Dong, G1
Li, ZR1
Wang, KD1
Guo, PP1
Kong, LY1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Heilmann, G1
Hien, P1
de Graaf, EM1
Oosterveld, M1
Tjabbes, T1
Stricker, BH1
Afonso Pérez, E1
Pego Reigosa, R1
Lancho Seco, A1
Brañas Fernández, F1
Roberts, SM1
Harbison, RD1
Seng, JE1
James, RC1
Obata, T1
Egashira, T1
Yamanaka, Y1

Reviews

2 reviews available for clonidine and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016
[Tizanidine-induced toxic hepatitis].
    Medicina clinica, 1999, Apr-10, Volume: 112, Issue:12

    Topics: Aged; Cerebral Infarction; Chemical and Drug Induced Liver Injury; Clonidine; Drug Therapy, Combinat

1999

Other Studies

8 other studies available for clonidine and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Multifunctional tacrine-trolox hybrids for the treatment of Alzheimer's disease with cholinergic, antioxidant, neuroprotective and hepatoprotective properties.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Alzheimer Disease; Animals; Antioxidants; Biphenyl Compounds; Blood-Brain Barrier; Cell Survival; Ch

2015
[Clonidine therapy as cause of lupus erythematosus].
    Deutsche medizinische Wochenschrift (1946), 1994, Jun-10, Volume: 119, Issue:23

    Topics: Angiotensin-Converting Enzyme Inhibitors; Chemical and Drug Induced Liver Injury; Clonidine; Humans;

1994
A case of tizanidine-induced hepatic injury.
    Journal of hepatology, 1996, Volume: 25, Issue:5

    Topics: Chemical and Drug Induced Liver Injury; Clonidine; Female; Humans; Liver; Liver Diseases; Middle Age

1996
Potentiation of carbon tetrachloride hepatotoxicity by phenylpropanolamine.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2

    Topics: Animals; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Clonidine;

1991
Amine oxidase released into plasma of rats treated with hepatotoxin allyl formate.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 66, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Clonidine; Formates; Formic Acid Esters; Kinetics;

1989