Page last updated: 2024-10-25

clonidine and Acute Disease

clonidine has been researched along with Acute Disease in 101 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"To determine the efficacy and safety of oral clonidine in decreasing the prevalence and intensity of postoperative intraocular pressure (IOP) rise in those undergoing phacoemulsification."9.15Effect of oral clonidine on acute intraocular pressure rise after phacoemulsification: a prospective double-blind, randomized, clinical trial. ( Boroojeny, SB; Fard, MM; Ghaffarpasand, F; Hourang, MH; Zakeri, H; Zeraatian, S, 2011)
"Tizanidine and aceclofenac individually have shown efficacy in the treatment of low back pain."9.14Aceclofenac-tizanidine in the treatment of acute low back pain: a double-blind, double-dummy, randomized, multicentric, comparative study against aceclofenac alone. ( Ambade, R; Bartakke, G; Chandanwale, AS; Chandurkar, N; Gupta, A; Pareek, A, 2009)
"The acute effect of 75 and 150 microg of clonidine administered orally in acute states of strong aversive inner tension and urge to commit self-injurious behavior was examined in 14 female patients meeting DSM-IV criteria for borderline personality disorder."9.11Clonidine in acute aversive inner tension and self-injurious behavior in female patients with borderline personality disorder. ( Bohus, M; Lieb, K; Peters, J; Philipsen, A; Richter, H; Rüsch, N; Schmahl, C, 2004)
"The role of digoxin and verapamil in the control of ventricular response in rapid atrial fibrillation is well established."9.09Clinical assessment of clonidine in the treatment of new-onset rapid atrial fibrillation: a prospective, randomized clinical trial. ( Abdollah, H; Ghali, WA; Moritz, S; Sanfilippo, AJ; Simpson, CS, 2001)
"In a double-blind trial tizanidine (DS 103-282: 5-Chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole), a new muscle relaxant, was compared with diazepam in twenty in-patients suffering from acute paravertebral muscle spasm."9.05Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam. ( Fryda-Kaurimsky, Z; Müller-Fassbender, H, 1981)
"The case of a 59-year-old healthy woman is described, who developed an extreme sinus bradycardia (30/min) with chest pain and acute right heart failure associated with gastrointestinal symptoms and elevation of the liver enzymes while simultaneously taking tizanidine (Sirdalud), diclofenac (Voltaren), and rofecoxib (Vioxx)."7.73[Extreme sinus bradycardia (30/min) with acute right heart failure under tizanidine (Sirdalud). Possible pharmacological interaction with rofecoxib (Vioxx)]. ( Bertoli, R; Caduff Janosa, P; Cerny, A; Kick, A; Moschovitis, G, 2005)
" Eighteen months later the mother was discovered while providing clonidine pills to the child; the mother appears to feature a Munchausen syndrome by proxy."7.71Permanent brain damage following acute clonidine poisoning in Munchausen by proxy. ( Domenici, R; Gavazzi, C; Mascalchi, M; Matteucci, L; Tessa, C, 2001)
"We describe two cases of severe colonic pseudo-obstruction (Ogilvie's Syndrome) after high dose clonidine i."7.69Acute colonic pseudoobstruction (Ogilvie's syndrome) in two patients receiving high dose clonidine for delirium tremens. ( Cantieni, R; Frutiger, A; Stieger, DS, 1997)
"We report five consecutive cases of patients with acute pancreatitis resistant to conventional treatment who improved dramatically with clonidine."7.68Clonidine treatment of acute pancreatitis: report of five cases. ( Cabrera, A; Jara, H; Jiménez, V; Lechín, A; Lechín, F; Lechín, M; Orozco, B; Rada, I; Valderrama, T; Van der Dijs, B, 1992)
"We report five cases of patients with acute pancreatitis (AP) resistant to conventional treatment who improved dramatically with clonidine."7.68Dramatic improvement with clonidine in acute pancreatitis with elevated catecholamine and cortisol plasma levels: report of five cases. ( Cabrera, A; Jara, H; Jiménez, V; Lechin, A; Lechin, F; Lechin, M; Orozco, B; Rada, I; Valderrama, T; van der Dijs, B, 1992)
"Muscle spasm is an involuntary, painful contraction of muscles that interferes with the function and cause of muscular disorder."6.73Efficacy of thiocolchicoside in Indian patients suffering from low back pain associated with muscle spasm. ( Joshi, N; Soonawalla, DF, 2008)
"The parameters of postoperative pain level using VAS score (visual analog scale), sedation and analgesics consumption were determined as outcome measures at 1, 2, 6, and 24 h of the operation."6.73Effects of clonidine preemptive analgesia on acute postoperative pain in abdominal surgery. ( Buković, D; Buković, N; Husedzinović, I; Pavelić, L; Persec, J; Persec, Z, 2007)
"Headache was the presenting and most prominent complaint, with daily episodes of short-lasting, intermittent, and paroxysmal attacks."5.31Recurrent short-lasting headache associated with paroxysmal hypertension: a clonidine-responsive syndrome. ( Dodick, DW, 2000)
"To determine the efficacy and safety of oral clonidine in decreasing the prevalence and intensity of postoperative intraocular pressure (IOP) rise in those undergoing phacoemulsification."5.15Effect of oral clonidine on acute intraocular pressure rise after phacoemulsification: a prospective double-blind, randomized, clinical trial. ( Boroojeny, SB; Fard, MM; Ghaffarpasand, F; Hourang, MH; Zakeri, H; Zeraatian, S, 2011)
"Tizanidine and aceclofenac individually have shown efficacy in the treatment of low back pain."5.14Aceclofenac-tizanidine in the treatment of acute low back pain: a double-blind, double-dummy, randomized, multicentric, comparative study against aceclofenac alone. ( Ambade, R; Bartakke, G; Chandanwale, AS; Chandurkar, N; Gupta, A; Pareek, A, 2009)
" Forty eight patients with acute organophosphate poisoning were randomized to receive either clonidine or placebo: Four to receive placebo and twelve to receive clonidine at each dose level."5.14A phase II clinical trial to assess the safety of clonidine in acute organophosphorus pesticide poisoning. ( Abeysinghe, C; Buckley, NA; Dawson, AH; Hettiarachchi, R; Jayamanna, SF; Karunatilake, H; Perera, PM, 2009)
"The acute effect of 75 and 150 microg of clonidine administered orally in acute states of strong aversive inner tension and urge to commit self-injurious behavior was examined in 14 female patients meeting DSM-IV criteria for borderline personality disorder."5.11Clonidine in acute aversive inner tension and self-injurious behavior in female patients with borderline personality disorder. ( Bohus, M; Lieb, K; Peters, J; Philipsen, A; Richter, H; Rüsch, N; Schmahl, C, 2004)
"The role of digoxin and verapamil in the control of ventricular response in rapid atrial fibrillation is well established."5.09Clinical assessment of clonidine in the treatment of new-onset rapid atrial fibrillation: a prospective, randomized clinical trial. ( Abdollah, H; Ghali, WA; Moritz, S; Sanfilippo, AJ; Simpson, CS, 2001)
"To determine the effect of apraclonidine hydrochloride on the acute intraocular pressure (IOP) rise after argon laser iridotomy (ALI), a double-masked comparative study was carried out."5.07Effect of apraclonidine hydrochloride on acute introacular pressure rise after argon laser iridotomy. ( Hong, C; Park, WH; Sohn, YH; Song, KY, 1991)
"In a double-blind trial tizanidine (DS 103-282: 5-Chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole), a new muscle relaxant, was compared with diazepam in twenty in-patients suffering from acute paravertebral muscle spasm."5.05Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam. ( Fryda-Kaurimsky, Z; Müller-Fassbender, H, 1981)
"The case of a 59-year-old healthy woman is described, who developed an extreme sinus bradycardia (30/min) with chest pain and acute right heart failure associated with gastrointestinal symptoms and elevation of the liver enzymes while simultaneously taking tizanidine (Sirdalud), diclofenac (Voltaren), and rofecoxib (Vioxx)."3.73[Extreme sinus bradycardia (30/min) with acute right heart failure under tizanidine (Sirdalud). Possible pharmacological interaction with rofecoxib (Vioxx)]. ( Bertoli, R; Caduff Janosa, P; Cerny, A; Kick, A; Moschovitis, G, 2005)
"The chronic pain relieving effects following spinal administration of clonidine are probably connected to alpha2-adrenoreceptor-induced augmented synthesis of nitric oxide (NO) in the spinal cord."3.73Involvement of nitric oxide in clonidine-induced spinal analgesia. ( Aronov, S; Ben-Abraham, R; Givati-Divshi, D; Katz, Y, 2005)
" Eighteen months later the mother was discovered while providing clonidine pills to the child; the mother appears to feature a Munchausen syndrome by proxy."3.71Permanent brain damage following acute clonidine poisoning in Munchausen by proxy. ( Domenici, R; Gavazzi, C; Mascalchi, M; Matteucci, L; Tessa, C, 2001)
" Bradycardia was induced in rats by administering the bradycardic drug alinidine (3 mg/kg body weight) twice daily."3.70Bradycardia-induced coronary angiogenesis is dependent on vascular endothelial growth factor. ( Bjercke, RJ; Brock, TA; Brown, MD; Tomanek, RJ; Zheng, W, 1999)
"We describe two cases of severe colonic pseudo-obstruction (Ogilvie's Syndrome) after high dose clonidine i."3.69Acute colonic pseudoobstruction (Ogilvie's syndrome) in two patients receiving high dose clonidine for delirium tremens. ( Cantieni, R; Frutiger, A; Stieger, DS, 1997)
"We report five consecutive cases of patients with acute pancreatitis resistant to conventional treatment who improved dramatically with clonidine."3.68Clonidine treatment of acute pancreatitis: report of five cases. ( Cabrera, A; Jara, H; Jiménez, V; Lechín, A; Lechín, F; Lechín, M; Orozco, B; Rada, I; Valderrama, T; Van der Dijs, B, 1992)
"We report five cases of patients with acute pancreatitis (AP) resistant to conventional treatment who improved dramatically with clonidine."3.68Dramatic improvement with clonidine in acute pancreatitis with elevated catecholamine and cortisol plasma levels: report of five cases. ( Cabrera, A; Jara, H; Jiménez, V; Lechin, A; Lechin, F; Lechin, M; Orozco, B; Rada, I; Valderrama, T; van der Dijs, B, 1992)
"A patient with essential hypertension treated with clonidine developed accelerated acute clonidine withdrawal syndrome during coronary artery bypass surgery."3.66Accelerated acute clonidine withdrawal syndrome during coronary artery bypass surgery. A case report. ( O'Connor, DE, 1981)
"Muscle spasm is an involuntary, painful contraction of muscles that interferes with the function and cause of muscular disorder."2.73Efficacy of thiocolchicoside in Indian patients suffering from low back pain associated with muscle spasm. ( Joshi, N; Soonawalla, DF, 2008)
"The parameters of postoperative pain level using VAS score (visual analog scale), sedation and analgesics consumption were determined as outcome measures at 1, 2, 6, and 24 h of the operation."2.73Effects of clonidine preemptive analgesia on acute postoperative pain in abdominal surgery. ( Buković, D; Buković, N; Husedzinović, I; Pavelić, L; Persec, J; Persec, Z, 2007)
"2) treatment on the withdrawal symptoms associated with smoking cessation."2.66Effects of transdermal clonidine treatment on withdrawal symptoms associated with smoking cessation. A randomized, controlled trial. ( McAdams, LA; Ornish, SA; Zisook, S, 1988)
"Clonidine was more effective than chlordiazepoxide at reducing alcohol withdrawal scale scores, systolic blood pressures, and heart rates over the entire study period."2.66Clonidine vs chlordiazepoxide in the management of acute alcohol withdrawal syndrome. ( Baumgartner, GR; Rowen, RC, 1987)
"Evidence on the treatment of tardive akathisia is unsatisfactory."2.41Managing antipsychotic-induced acute and chronic akathisia. ( Fleischhacker, WW; Miller, CH, 2000)
"Patients with acute hypertension have substantial concomitant morbidity and mortality, and intravenous antihypertensive treatment is associated with hypotension in almost 10% of cases."1.37Characteristics, practice patterns, and outcomes in patients with acute hypertension: European registry for Studying the Treatment of Acute hyperTension (Euro-STAT). ( Anderson, FA; de La Garanderie, DP; Emery, L; Gore, JM; Rushton-Smith, S; Vincent, JL; Vuylsteke, A; Wyman, A, 2011)
"Buprenorphine has been approved for heroin detoxification, but little is known about its impact on everyday practice."1.34Buprenorphine for acute heroin detoxification: diffusion of research into practice. ( Boverman, JF; Kovas, AE; McCarty, DJ; McFarland, BH; Thayer, JA, 2007)
"Treating this pain is often difficult, particularly in elderly patients, owing to iatrogenic effects and to interactions with the pre-existing diseases and treatments frequently present in this age group."1.32[Facial anesthetic blocks in the treatment of acute pain during ophthalmic zoster]. ( Chiquet, C; Gain, P; Maugery, J; Michaud, P; Navez, ML; Pascal, J; Thuret, G, 2003)
"One of the treatment alternative of withdrawal symptoms of patients suffering from opiate dependence is to apply the clonidine in combination or itself."1.31[Tizanidine in the treatment of acute withdrawal symptoms in heroin dependent patients]. ( Csorba, J; Gerevich, J; Kiss, N; Sós, I, 2000)
"Headache was the presenting and most prominent complaint, with daily episodes of short-lasting, intermittent, and paroxysmal attacks."1.31Recurrent short-lasting headache associated with paroxysmal hypertension: a clonidine-responsive syndrome. ( Dodick, DW, 2000)
"Cisapride was ineffective at 1 mg/kg but caused a partial reversal at the 5- and 10-mg/kg doses (46."1.30Acute intracranial hypertension-induced inhibition of gastric emptying: evaluation in conscious rats. ( Gupta, YK; Kacker, V; Mehta, VS, 1999)
"The atipamezole-induced increase in LC activity and blood pressure was significantly attenuated by pretreatment with DGG (200 micrograms i."1.29The role of excitatory amino acids in the expression of precipitated acute and chronic clonidine withdrawal: an in vivo voltammetric study in the rat locus coeruleus. ( Duggan, S; Hong, M; Jhamandas, K; Milne, B, 1994)
" Neuroleptic medications are still the mainstay of treatment, but recent studies suggest new approaches to dosage and to the treatment of acute psychosis."1.27The pharmacologic treatment of schizophrenia: a progress report. ( Baldessarini, RJ; Donaldson, SR; Gelenberg, AJ, 1983)
"A patient with long-standing Tourette's syndrome had a dramatic exacerbation of symptoms following the rapid withdrawal of haloperidol."1.27Clonidine in the treatment of Tourette's syndrome exacerbation due to haloperidol withdrawal. ( Max, JE; Rasmussen, SA, 1986)

Research

Studies (101)

TimeframeStudies, this research(%)All Research%
pre-199034 (33.66)18.7374
1990's23 (22.77)18.2507
2000's35 (34.65)29.6817
2010's9 (8.91)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Galland, C1
Sergent, B1
Pichot, C1
Ghignone, M1
Quintin, L2
Gowing, L5
Farrell, M1
Ali, R5
White, JM3
Mbewe, D1
Soonawalla, DF1
Joshi, N1
Dewan, MA1
Harrison, AR1
Lee, MS1
Pareek, A1
Chandurkar, N1
Chandanwale, AS1
Ambade, R1
Gupta, A1
Bartakke, G1
Martín-Moro, JG1
Botín, DM1
Muñoz-Negrete, FJ1
Perera, PM1
Jayamanna, SF1
Hettiarachchi, R1
Abeysinghe, C1
Karunatilake, H1
Dawson, AH1
Buckley, NA1
Rubino, AS1
Onorati, F1
Caroleo, S1
Galato, E1
Nucera, S1
Amantea, B1
Santini, F1
Renzulli, A1
Beer, GM1
Goldscheider, E1
Weber, A1
Lehmann, K1
Burgher, AH1
Hoelzer, BC1
Schroeder, DR1
Wilson, GA1
Huntoon, MA1
Zeraatian, S1
Zakeri, H1
Boroojeny, SB1
Hourang, MH1
Ghaffarpasand, F1
Fard, MM1
Ruksin, VV1
Grishin, OV1
Vuylsteke, A1
Vincent, JL1
de La Garanderie, DP1
Anderson, FA1
Emery, L1
Wyman, A1
Rushton-Smith, S1
Gore, JM1
Homayoun, H1
Khavandgar, S1
Zarrindast, MR1
Gain, P1
Thuret, G1
Chiquet, C1
Pascal, J1
Michaud, P1
Maugery, J1
Navez, ML1
Simanski, C1
Neugebauer, E1
Harris, AC1
Gewirtz, JC1
Oliveira-Filho, J1
Silva, SC1
Trabuco, CC1
Pedreira, BB1
Sousa, EU1
Bacellar, A1
Karmen, NB1
Sobey, PW1
Parran, TV1
Grey, SF1
Adelman, CL1
Yu, J1
Schrader, J1
Diener, HC1
Lüders, S1
Philipsen, A1
Richter, H1
Schmahl, C1
Peters, J1
Rüsch, N1
Bohus, M1
Lieb, K1
White, J2
Fiscella, K1
Moore, A1
Engerman, J1
Meldrum, S1
Kick, A1
Bertoli, R1
Moschovitis, G1
Caduff Janosa, P1
Cerny, A1
Ketenci, A1
Ozcan, E1
Karamursel, S1
Aronov, S2
Ben-Abraham, R2
Givati-Divshi, D2
Katz, Y2
Kovas, AE1
McFarland, BH1
McCarty, DJ1
Boverman, JF1
Thayer, JA1
Lavelle, W1
Lavelle, ED1
Lavelle, L1
Hajduk, A1
Sein Anand, J1
Chodorowski, Z1
Persec, J1
Persec, Z1
Buković, D1
Husedzinović, I1
Buković, N1
Pavelić, L1
Lechin, F3
van der Dijs, B3
Hernandez-Adrian, G1
Moodley, J1
Houston, MC1
Donaldson, SR1
Gelenberg, AJ1
Baldessarini, RJ1
Borokhova, IA1
Fryda-Kaurimsky, Z1
Müller-Fassbender, H1
Brandt, D2
Marochkov, AV1
Konchik, IS1
Gold, MS2
Pottash, AL1
Extein, I1
Stoll, A1
O'Connor, DE1
Esser, H1
Kikis, D1
Stumpe, KO1
Krück, F1
Elizur, A1
Liberson, Z1
Bender, F1
Iakhno, NN1
Damulin, IV1
Chernenko, OA1
Ianakaeva, TA1
Kondrat'eva, ON1
Kur'ianova, PT1
Prattichizzo, FA1
Galetta, F1
Bonechi, I1
Giusti, C1
Duggan, S1
Hong, M1
Milne, B1
Jhamandas, K1
Sacchetti, A1
McCabe, J1
Torres, M1
Harris, RL1
Foo, IT1
Warren, PM1
Drummond, GB1
Miampamba, M1
Chéry-Croze, S1
Détolle-Sarbach, S1
Guez, D1
Chayvialle, JA1
Perera, I1
Stieger, DS1
Cantieni, R1
Frutiger, A1
Lierz, P1
Ekelund, U1
Björnberg, J1
Mellander, S1
Kacker, V1
Mehta, VS1
Gupta, YK1
Preston, RA1
Baltodano, NM1
Cienki, J1
Materson, BJ1
Zheng, W1
Brown, MD1
Brock, TA1
Bjercke, RJ1
Tomanek, RJ1
Miller, CH1
Fleischhacker, WW1
Sharma, S1
Cheung, J1
Sós, I1
Kiss, N1
Csorba, J1
Gerevich, J1
Dodick, DW1
Yochelson, MR1
David, RG1
Lai, JS1
Tham, CC1
Chua, JK1
Lam, DS1
Tessa, C1
Mascalchi, M1
Matteucci, L1
Gavazzi, C1
Domenici, R1
Simpson, CS1
Ghali, WA1
Sanfilippo, AJ1
Moritz, S1
Abdollah, H1
Pozniak-Patewicz, E1
Redmond, DE1
Kleber, HD1
Congdon, PJ1
Forsythe, WI1
Männistö, PT1
Kokkonen, J1
Ranta, T1
Strauss, FG1
Franklin, SS1
Lewin, AJ1
Maxwell, MH1
Rahn, KH1
Haas, Th1
Denkl, P1
Brodsky, JB1
Bravo, JJ1
Lechín, M2
Jara, H2
Lechín, A2
Cabrera, A2
Rada, I2
Orozco, B2
Jiménez, V2
Valderrama, T2
Trestman, RL2
Lawrence, TL1
Coccaro, EF2
Harvey, P1
Bernstein, D2
Lawrence, EK1
Condello, V1
Mahon, T1
Yang, RK1
Knott, P1
Rubin, J1
Boell, R1
Siever, LJ1
Gabriel, SM1
Owen, K1
Moran, M1
Lawrence, T1
Rosenthal, J1
Horvath, TB1
Hong, C1
Song, KY1
Park, WH1
Sohn, YH1
Ip Yam, PC1
Forbes, A1
Kox, WJ1
Luzhnikov, EA1
Savina, AS1
Sukhodolova, GA1
Payen, D1
Plaisance, P1
Chiron, B1
Lhoste, F1
Krawitz, PL1
Podos, SM1
Lesch, KP1
Laux, G1
Pfüller, H1
Schulte, M1
Fruncillo, RJ1
Gibbons, WJ1
Vlasses, PH1
Ferguson, RK1
Namer, IJ1
Kansu, T1
Zileli, T1
Ornish, SA1
Zisook, S1
McAdams, LA1
Baumgartner, GR2
Rowen, RC1
Max, JE1
Rasmussen, SA1
Lutskiĭ, IaM1
Tabolin, VA1
Melnik, VA1
Fediaev, VA1
Sukhodolova, GN1
Castellano, G1
Santalla, F1
Puras, A1
Alvarez Machín, N1
Vidal, JV1
Morillas, JD1
Muñoz, MT1
Solís Herruzo, JA1
Romeo, DP1
Solomon, GD1
Hover, AR1
Brod, J1
Anavekar, SN1
Johnston, CI1
Persico, L1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study of Transforaminal Epidural Injection of Clonidine for the Treatment of Acute Lumbosacral Radiculopathy[NCT00588354]26 participants (Actual)Interventional2006-10-31Terminated (stopped due to Targeted enrollment was not reached.)
Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol[NCT02403349]Phase 4105 participants (Actual)Interventional2012-05-31Active, not recruiting
A Phase III, Multicenter, Randomized Study to Assess the Efficacy and Safety of 0,5 mg Tizaspray® Administered Intranasally Versus Sirdalud® 2 mg Tablets, in Patients With Acute Low Back Pain[NCT02934061]Phase 3117 participants (Actual)Interventional2016-10-31Completed
Emergency Department Interventions to Improve Blood Pressure Follow-up[NCT00798551]10 participants (Actual)Interventional2008-04-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Pain Disability Score at 2 Weeks as Measured by Oswestry Low Back Pain Disability Questionnaire (ODI)

This questionnaire measures a patient's permanent functional disability. The questionnaire consists of 10 sections with 6 statements each of increasing point value (from 0 to 5). The score is a percentage of the total, with higher score showing greater disability. Minimum detectable change is 10%, with a 90% CI. Change of less than this may be attributable to error in measurement. (NCT00588354)
Timeframe: 2 weeks

InterventionUnits on a scale (Mean)
2% Lidocaine and Clonidine (200 or 400 ug)27.0
2% Lidocaine and Triamcinolone (40 mg)21.3

Pain Disability Score at 2 Weeks as Measured by the Roland-Morris Disability Questionnaire

This scale measures functional disability due to back pain. The score of the scale is the total number of items checked, from a minimum of 0 (no disability) to a maximum of 24 (great disability). Roland MO, Morris RW. A study of the natural history of back Pain. Part 1: development of a reliable and sensitive measure of disability in low back pain. Spine 1983; 8:141-144. (NCT00588354)
Timeframe: 2 weeks

InterventionUnits on a scale (Mean)
2% Lidociane and Clonidine (200 or 400 ug)9.6
2% Lidocaine and Triamcinolone (40 mg)5.7

Pain Disability Score at 4 Weeks as Measured by Oswestry Low Back Pain Disability Questionnaire

This questionnaire measures a patient's permanent functional disability. The questionnaire consists of 10 sections with 6 statements each of increasing point value (from 0 to 5). The score is a percentage of the total, with higher score showing greater disability. Minimum detectable change is 10%, with a 90% CI. Change of less than this may be attributable to error in measurement. (NCT00588354)
Timeframe: 4 weeks

InterventionUnits on a scale (Mean)
2% Lidociane and Clonidine (200 or 400 ug)23.9
2% Lidocaine and Triamcinolone (40 mg)17.0

Pain Disability Score at 4 Weeks as Measured by the Roland-Morris Disability Questionnaire

This scale measures functional disability due to back pain. The score of the scale is the total number of items checked, from a minimum of 0 (no disability) to a maximum of 24 (great disability). Roland MO, Morris RW. A study of the natural history of back Pain. Part 1: development of a reliable and sensitive measure of disability in low back pain. Spine 1983; 8:141-144. (NCT00588354)
Timeframe: 4 weeks

InterventionUnits on a scale (Mean)
2% Lidociane and Clonidine (200 or 400 ug)9.4
2% Lidocaine and Triamcinolone (40 mg)3.5

Pain Intensity Score at 2 Weeks as Measured by Pain Intensity Numerical Rating Scale (PI-NRS)

11-point ordinal scale measuring patient pain, ranging from 0 (no pain) to 10 (most severe/disabling pain). (NCT00588354)
Timeframe: 2 weeks

InterventionUnits on a scale (Mean)
2% Lidociane and Clonidine (200 or 400 ug)4.1
2% Lidocaine and Triamcinolone (40 mg)4.0

Pain Intensity Score at 4 Weeks as Measured by Pain Intensity Numerical Rating Scale (PI-NRS)

11-point ordinal scale measuring patient pain, ranging from 0 (no pain) to 10 (most severe/disabling pain). (NCT00588354)
Timeframe: 4 weeks

InterventionUnits on a scale (Mean)
2% Lidociane and Clonidine (200 or 400 ug)4.1
2% Lidocaine and Triamcinolone (40 mg)2.7

Pain Score at 2 Weeks as Measured by the Multidimensional Pain Inventory (MPI)

The MPI is a comprehensive instrument comprised of 12 scales divided into three parts for assessing a number of dimensions of the chronic pain experience including pain intensity, emotional distress, cognitive and functional adaptation, and social support. Reference: Kearns RO, Turk DC, Rudy TC. The West Haven-Yale Multidimensional Pain Inventory (WHYMPI). Pain 1985; 23:345-356. Subscales were not used; the DOS WHYMPI computer program version 2.1 was used to score the instrument. Scores range from 0 (no pain) to 100 (highest pain). A score of 50 is the mean for patients with chronic pain. (NCT00588354)
Timeframe: 2 weeks

InterventionUnits on a scale (Mean)
2% Lidociane and Clonidine (200 or 400 ug)51.6
2% Lidocaine and Triamcinolone (40 mg)56.0

Pain Score at 4 Weeks as Measured by the Multidimensional Pain Inventory (MPI)

The MPI is a comprehensive instrument comprised of 12 scales divided into three parts for assessing a number of dimensions of the chronic pain experience including pain intensity, emotional distress, cognitive and functional adaptation, and social support. Reference: Kearns RO, Turk DC, Rudy TC. The West Haven-Yale Multidimensional Pain Inventory (WHYMPI). Pain 1985; 23:345-356. Subscales were not used; the DOS WHYMPI computer program version 2.1 was used to score the instrument. Scores range from 0 (no pain) to 100 (highest pain). A score of 50 is the mean for patients with chronic pain. (NCT00588354)
Timeframe: 4 weeks

InterventionUnits on a scale (Mean)
2% Lidociane and Clonidine (200 or 400 ug)56.7
2% Lidocaine and Triamcinolone (40 mg)56.9

Reviews

13 reviews available for clonidine and Acute Disease

ArticleYear
Alpha₂-adrenergic agonists for the management of opioid withdrawal.
    The Cochrane database of systematic reviews, 2016, May-03, Issue:5

    Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Clonidine; Controlled Clinical Trials as Topic;

2016
Buprenorphine for managing opioid withdrawal.
    The Cochrane database of systematic reviews, 2017, 02-21, Volume: 2

    Topics: Acute Disease; Buprenorphine; Clonidine; Female; Humans; Male; Methadone; Narcotic Antagonists; Opia

2017
Buprenorphine for the management of opioid withdrawal.
    The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3

    Topics: Acute Disease; Buprenorphine; Clonidine; Humans; Narcotic Antagonists; Opioid-Related Disorders; Ran

2009
[Postoperative pain therapy].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2003, Volume: 74, Issue:3

    Topics: Acute Disease; Adrenergic alpha-Agonists; Analgesia; Analgesia, Patient-Controlled; Analgesics; Anal

2003
Buprenorphine for the management of opioid withdrawal.
    The Cochrane database of systematic reviews, 2004, Oct-18, Issue:4

    Topics: Acute Disease; Buprenorphine; Clonidine; Humans; Narcotic Antagonists; Opioid-Related Disorders; Ran

2004
Buprenorphine for the management of opioid withdrawal.
    The Cochrane database of systematic reviews, 2006, Apr-19, Issue:2

    Topics: Acute Disease; Buprenorphine; Clonidine; Humans; Narcotic Antagonists; Opioid-Related Disorders; Ran

2006
Intra-articular injections.
    The Medical clinics of North America, 2007, Volume: 91, Issue:2

    Topics: Acute Disease; Adrenal Cortex Hormones; Anesthetics, Local; Arthralgia; Chronic Disease; Clonidine;

2007
The management of hypertension in pregnancy: A review.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jul-19, Volume: 58, Issue:3

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anesthesia, Epidural; Anesthesia, Obstetrical; Anticoagu

1980
Abrupt cessation of treatment in hypertension: consideration of clinical features, mechanisms, prevention and management of the discontinuation syndrome.
    American heart journal, 1981, Volume: 102, Issue:3 Pt 1

    Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bethanidine; Blood Pressure; Cloni

1981
[Significance of free fatty acid levels in evaluating the severity of myocardial infarction and the efficacy of drug therapy].
    Kardiologiia, 1984, Volume: 24, Issue:12

    Topics: Acute Disease; Arrhythmias, Cardiac; Catecholamines; Clonidine; Fatty Acids, Nonesterified; Follow-U

1984
[Therapy of hypertensive crisis].
    Wiener medizinische Wochenschrift (1946), 1980, May-31, Volume: 130, Issue:10

    Topics: Acute Disease; Bed Rest; Cardiac Glycosides; Clonidine; Diazoxide; Dihydralazine; Diuretics; Heart F

1980
Managing antipsychotic-induced acute and chronic akathisia.
    Drug safety, 2000, Volume: 22, Issue:1

    Topics: Acute Disease; Akathisia, Drug-Induced; Amantadine; Antipsychotic Agents; Benzodiazepines; Cholinerg

2000
Recent advances in therapy. Antihypertensive and antibacterial agents.
    Progress in biochemical pharmacology, 1972, Volume: 7

    Topics: Acute Disease; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Antihyp

1972

Trials

21 trials available for clonidine and Acute Disease

ArticleYear
Efficacy of thiocolchicoside in Indian patients suffering from low back pain associated with muscle spasm.
    Journal of the Indian Medical Association, 2008, Volume: 106, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Analgesics; Clonidine; Colchicine; Female; Humans; India

2008
Aceclofenac-tizanidine in the treatment of acute low back pain: a double-blind, double-dummy, randomized, multicentric, comparative study against aceclofenac alone.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2009, Volume: 18, Issue:12

    Topics: Activities of Daily Living; Acute Disease; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Ag

2009
A phase II clinical trial to assess the safety of clonidine in acute organophosphorus pesticide poisoning.
    Trials, 2009, Aug-20, Volume: 10

    Topics: Acute Disease; Adult; Antidotes; Clonidine; Female; Humans; Male; Middle Aged; Organophosphate Poiso

2009
Impact of clonidine administration on delirium and related respiratory weaning after surgical correction of acute type-A aortic dissection: results of a pilot study.
    Interactive cardiovascular and thoracic surgery, 2010, Volume: 10, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Agonists; Aged; Aortic Aneurysm; Aortic Dissection; Central Nervous

2010
Transforaminal epidural clonidine versus corticosteroid for acute lumbosacral radiculopathy due to intervertebral disc herniation.
    Spine, 2011, Mar-01, Volume: 36, Issue:5

    Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Aged; Clonidine; Female; Humans; Injections, Epidural

2011
Effect of oral clonidine on acute intraocular pressure rise after phacoemulsification: a prospective double-blind, randomized, clinical trial.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2011, Volume: 27, Issue:3

    Topics: Acute Disease; Administration, Oral; Adrenergic alpha-2 Receptor Agonists; Aged; Clonidine; Double-B

2011
Detrimental effect of blood pressure reduction in the first 24 hours of acute stroke onset.
    Neurology, 2003, Oct-28, Volume: 61, Issue:8

    Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Female; Humans; Hypert

2003
Clonidine in acute aversive inner tension and self-injurious behavior in female patients with borderline personality disorder.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:10

    Topics: Acute Disease; Administration, Oral; Adrenergic alpha-Agonists; Adult; Ambulatory Care; Borderline P

2004
Assessment of efficacy and psychomotor performances of thiocolchicoside and tizanidine in patients with acute low back pain.
    International journal of clinical practice, 2005, Volume: 59, Issue:7

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adult; Clonidine; Colchicine; Double-Blind Method; Female;

2005
Effects of clonidine preemptive analgesia on acute postoperative pain in abdominal surgery.
    Collegium antropologicum, 2007, Volume: 31, Issue:4

    Topics: Abdomen; Acute Disease; Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Humans; Middle Aged; Pain

2007
Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam.
    The Journal of international medical research, 1981, Volume: 9, Issue:6

    Topics: Acute Disease; Adult; Back Pain; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method;

1981
[The efficacy of sirdalud in the drug therapy of pain in the spine].
    Terapevticheskii arkhiv, 1994, Volume: 66, Issue:10

    Topics: Acute Disease; Adult; Aged; Analgesics; Back Pain; Chronic Disease; Clonidine; Female; Humans; Male;

1994
Influence of oral clonidine on the ventilatory response to acute and sustained isocapnic hypoxia in human males.
    British journal of anaesthesia, 1996, Volume: 76, Issue:2

    Topics: Acute Disease; Administration, Oral; Adrenergic alpha-Agonists; Adult; Carbon Dioxide; Clonidine; Hu

1996
Clinical assessment of clonidine in the treatment of new-onset rapid atrial fibrillation: a prospective, randomized clinical trial.
    American heart journal, 2001, Volume: 142, Issue:2

    Topics: Acute Disease; Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressu

2001
Clonidine blocks acute opiate-withdrawal symptoms.
    Lancet (London, England), 1978, Sep-16, Volume: 2, Issue:8090

    Topics: Acute Disease; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Evaluation; Follow-Up

1978
Noradrenergic responses to clonidine in acute and remitted depressed male patients.
    Psychiatry research, 1992, Volume: 43, Issue:3

    Topics: Acute Disease; Aged; Arousal; Bipolar Disorder; Blood Pressure; Clonidine; Cohort Studies; Depressiv

1992
Clonidine in acute and chronic pain.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1992, Apr-18, Volume: 81, Issue:8

    Topics: Acute Disease; Chronic Disease; Clonidine; Female; Humans; Pain

1992
Effect of apraclonidine hydrochloride on acute introacular pressure rise after argon laser iridotomy.
    Korean journal of ophthalmology : KJO, 1991, Volume: 5, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Double-Blind Method; Female; Glauc

1991
Effects of transdermal clonidine treatment on withdrawal symptoms associated with smoking cessation. A randomized, controlled trial.
    Archives of internal medicine, 1988, Volume: 148, Issue:9

    Topics: Acute Disease; Administration, Cutaneous; Adult; Akathisia, Drug-Induced; Analysis of Variance; Anxi

1988
Clonidine versus chlordiazepoxide in acute alcohol withdrawal: a preliminary report.
    Southern medical journal, 1988, Volume: 81, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Chlordiazepoxide; Clinical Trials as Topic; Clonidine; Doubl

1988
Clonidine vs chlordiazepoxide in the management of acute alcohol withdrawal syndrome.
    Archives of internal medicine, 1987, Volume: 147, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Blood Pressure; Chlordiazepoxide; Clinical Trials as Topic;

1987

Other Studies

67 other studies available for clonidine and Acute Disease

ArticleYear
Acute iterative bronchospasm and "do not re-intubate" orders: sedation by an alpha-2 agonist combined with noninvasive ventilation.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:6

    Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Bronchial Spasm; Clonidine; Fatal Outcome; Huma

2015
False-negative apraclonidine testing in acute Horner syndrome.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2009, Volume: 44, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Agonists; Anisocoria; Carotid Artery, Internal, Dissection; Clonidin

2009
Possible effect of systemic sympathicolytic drugs on apraclonidine test.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2009, Volume: 44, Issue:4

    Topics: Acute Disease; Adrenergic alpha-Agonists; Anisocoria; Carotid Artery, Internal, Dissection; Clonidin

2009
Prevention of acute hematoma after face-lifts.
    Aesthetic plastic surgery, 2010, Volume: 34, Issue:4

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Antiemetics;

2010
[Acute management at the rising of arterial pressure which is not menacing to a life].
    Kardiologiia, 2011, Volume: 51, Issue:2

    Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged; Angiotensin-Converting Enzyme Inhibitors;

2011
Characteristics, practice patterns, and outcomes in patients with acute hypertension: European registry for Studying the Treatment of Acute hyperTension (Euro-STAT).
    Critical care (London, England), 2011, Volume: 15, Issue:6

    Topics: Acute Disease; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Emergency Service, Hospital

2011
Morphine state-dependent learning: interactions with alpha2-adrenoceptors and acute stress.
    Behavioural pharmacology, 2003, Volume: 14, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Avoidance Learning;

2003
[Facial anesthetic blocks in the treatment of acute pain during ophthalmic zoster].
    Journal francais d'ophtalmologie, 2003, Volume: 26, Issue:1

    Topics: Acute Disease; Adrenergic Agonists; Age Factors; Aged; Aged, 80 and over; Analgesics; Anesthetics, L

2003
Elevated startle during withdrawal from acute morphine: a model of opiate withdrawal and anxiety.
    Psychopharmacology, 2004, Volume: 171, Issue:2

    Topics: Acoustic Stimulation; Acute Disease; Animals; Chlordiazepoxide; Clonidine; Disease Models, Animal; I

2004
Oxidative modification of erythrocyte membranes in the acute stage of severe craniocerebral trauma and its correction with clonidine.
    Bulletin of experimental biology and medicine, 2003, Volume: 136, Issue:4

    Topics: Acute Disease; Adult; Antioxidants; Catalase; Clonidine; Cohort Studies; Craniocerebral Trauma; Drug

2003
The use of tramadol for acute heroin withdrawal: a comparison to clonidine.
    Journal of addictive diseases, 2003, Volume: 22, Issue:4

    Topics: Acute Disease; Adult; Analgesics, Opioid; Clinical Trials as Topic; Clonidine; Female; Heroin Depend

2003
[Treating high blood pressure in acute stroke].
    MMW Fortschritte der Medizin, 2004, Mar-11, Volume: 146, Issue:11

    Topics: Acute Disease; Adrenergic alpha-Agonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Conve

2004
Management of opiate detoxification in jails.
    Journal of addictive diseases, 2005, Volume: 24, Issue:1

    Topics: Acute Disease; Adrenergic alpha-Agonists; Clonidine; Health Care Surveys; Humans; Methadone; Narcoti

2005
[Extreme sinus bradycardia (30/min) with acute right heart failure under tizanidine (Sirdalud). Possible pharmacological interaction with rofecoxib (Vioxx)].
    Medizinische Klinik (Munich, Germany : 1983), 2005, Apr-15, Volume: 100, Issue:4

    Topics: Acute Disease; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Bradycardia; Clonidine; Cyclooxy

2005
Involvement of nitric oxide in clonidine-induced spinal analgesia.
    Drug metabolism and drug interactions, 2005, Volume: 21, Issue:1

    Topics: Acute Disease; Analgesia; Analgesics; Animals; Arginine; Clonidine; Injections, Spinal; Male; Methyl

2005
Cerebroventricular injection of clonidine causes analgesia mediated by a nitrogen pathway.
    Drug metabolism and drug interactions, 2005, Volume: 21, Issue:1

    Topics: Acute Disease; Analgesia; Analgesics; Animals; Arginine; Cerebral Ventricles; Clonidine; Injections;

2005
Buprenorphine for acute heroin detoxification: diffusion of research into practice.
    Journal of substance abuse treatment, 2007, Volume: 32, Issue:2

    Topics: Acute Disease; Adult; Buprenorphine; Clonidine; Diffusion of Innovation; Female; Heroin; Heroin Depe

2007
[Acute intoxication with clonidine--a case report].
    Przeglad lekarski, 2007, Volume: 64, Issue:4-5

    Topics: Acute Disease; Adult; Antidotes; Bradycardia; Clonidine; Female; Gastric Lavage; Humans; Hypertensio

2007
Clonidine therapy for pancreatitis.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:5

    Topics: Acute Disease; Adrenergic alpha-Agonists; Animals; Clonidine; Dogs; Humans; Pancreatitis

2008
The pharmacologic treatment of schizophrenia: a progress report.
    Schizophrenia bulletin, 1983, Volume: 9, Issue:4

    Topics: Acute Disease; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Ca

1983
[The hypertensive crisis].
    Wiener medizinische Wochenschrift (1946), 1984, Jul-31, Volume: 134, Issue:13-14

    Topics: Acute Disease; Calcium Channel Blockers; Clonidine; Coronary Disease; Diazoxide; Dihydralazine; Dilt

1984
[Cases of acute hemiton poisoning in children].
    Pediatriia, 1983, Issue:9

    Topics: Acute Disease; Child, Preschool; Clonidine; Humans; Infant

1983
Clinical utility of clonidine in opiate withdrawal.
    NIDA research monograph, 1981, Volume: 34

    Topics: Acute Disease; Adult; Blood Pressure; Clonidine; Humans; Inactivation, Metabolic; Naloxone; Opium; S

1981
Accelerated acute clonidine withdrawal syndrome during coronary artery bypass surgery. A case report.
    British journal of anaesthesia, 1981, Volume: 53, Issue:4

    Topics: Acute Disease; Clonidine; Coronary Artery Bypass; Humans; Hypertension; Hypotension; Intraoperative

1981
[Clonidine in the management of hypertensive crisis (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Jan-04, Volume: 105, Issue:1

    Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Clonidine; Female; Heart Rate; Humans; Hyperten

1980
An acute psychotic episode at the beginning of clonidine therapy.
    Progress in neuro-psychopharmacology, 1980, Volume: 4, Issue:2

    Topics: Acute Disease; Adult; Clonidine; Female; Humans; Hypertension; Psychoses, Substance-Induced

1980
Acute hypertensive crises.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1980, Volume: 3, Issue:1-2

    Topics: Acute Disease; Adult; Aged; Clonidine; Diazoxide; Heart Block; Humans; Hypertension; Injections, Int

1980
[Therapy of arterial hypertension associated with acute stroke. Current trends and problems].
    La Clinica terapeutica, 1994, Volume: 145, Issue:11

    Topics: Acute Disease; Aged; Antihypertensive Agents; Blood Pressure Monitors; Cerebral Hemorrhage; Cerebrov

1994
The role of excitatory amino acids in the expression of precipitated acute and chronic clonidine withdrawal: an in vivo voltammetric study in the rat locus coeruleus.
    Brain research, 1994, Dec-05, Volume: 665, Issue:2

    Topics: Acute Disease; Animals; Catechols; Chronic Disease; Clonidine; Electrophysiology; Excitatory Amino A

1994
ED management of acute congestive heart failure in renal dialysis patients.
    The American journal of emergency medicine, 1993, Volume: 11, Issue:6

    Topics: Acute Disease; Administration, Cutaneous; Administration, Oral; Administration, Sublingual; Captopri

1993
Antinociceptive effects of oral clonidine and S12813-4 in acute colon inflammation in rats.
    European journal of pharmacology, 1996, Jul-25, Volume: 308, Issue:3

    Topics: Acute Disease; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Colitis; Fem

1996
What you need to know: addiction--cough mixture.
    Singapore medical journal, 1997, Volume: 38, Issue:3

    Topics: Acute Disease; Adrenergic alpha-Agonists; Antitussive Agents; Chronic Disease; Clonidine; Codeine; D

1997
Acute colonic pseudoobstruction (Ogilvie's syndrome) in two patients receiving high dose clonidine for delirium tremens.
    Intensive care medicine, 1997, Volume: 23, Issue:7

    Topics: Acute Disease; Adrenergic alpha-Agonists; Aged; Alcohol Withdrawal Delirium; Clonidine; Colonic Pseu

1997
Pain management with spinal and epidural analgesia.
    Acta anaesthesiologica Scandinavica. Supplementum, 1997, Volume: 111

    Topics: Acute Disease; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; C

1997
Alpha 2-adrenoceptor activation may trigger the increased production of endothelium-derived nitric oxide in skeletal muscle during acute haemorrhage.
    Acta physiologica Scandinavica, 1998, Volume: 164, Issue:3

    Topics: Acute Disease; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cats;

1998
Acute intracranial hypertension-induced inhibition of gastric emptying: evaluation in conscious rats.
    European journal of pharmacology, 1999, Mar-12, Volume: 369, Issue:1

    Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; Antihypertensive Agents; Antipsychotic Agents; Bre

1999
Clinical presentation and management of patients with uncontrolled, severe hypertension: results from a public teaching hospital.
    Journal of human hypertension, 1999, Volume: 13, Issue:4

    Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Cross-S

1999
Bradycardia-induced coronary angiogenesis is dependent on vascular endothelial growth factor.
    Circulation research, 1999, Jul-23, Volume: 85, Issue:2

    Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; Antibodies; Blotting, Northern; Blotting, Western; B

1999
Ophthaproblem. Acute angle-closure glaucoma.
    Canadian family physician Medecin de famille canadien, 2000, Volume: 46

    Topics: Acetazolamide; Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Carbonic Anhyd

2000
[Tizanidine in the treatment of acute withdrawal symptoms in heroin dependent patients].
    Orvosi hetilap, 2000, Apr-09, Volume: 141, Issue:15

    Topics: Acute Disease; Adult; Analgesics; Anticonvulsants; Case-Control Studies; Clonidine; Female; Heroin;

2000
Recurrent short-lasting headache associated with paroxysmal hypertension: a clonidine-responsive syndrome.
    Cephalalgia : an international journal of headache, 2000, Volume: 20, Issue:5

    Topics: Acute Disease; Aged; Antihypertensive Agents; Clonidine; Headache; Humans; Hypertension; Male; Middl

2000
New-onset tic disorder following acute hemorrhage of an arteriovenous malformation.
    Journal of child neurology, 2000, Volume: 15, Issue:11

    Topics: Acute Disease; Adolescent; Adrenergic alpha-Agonists; Cerebral Hemorrhage; Clonidine; Craniotomy; Di

2000
Immediate diode laser peripheral iridoplasty as treatment of acute attack of primary angle closure glaucoma: a preliminary study.
    Journal of glaucoma, 2001, Volume: 10, Issue:2

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Clon

2001
Permanent brain damage following acute clonidine poisoning in Munchausen by proxy.
    Neuropediatrics, 2001, Volume: 32, Issue:2

    Topics: Acute Disease; Brain Damage, Chronic; Child, Preschool; Clonidine; Diagnosis, Differential; Heart Ar

2001
Clonidine in acute migraine.
    Lancet (London, England), 1976, Oct-30, Volume: 2, Issue:7992

    Topics: Acute Disease; Adult; Clonidine; Female; Humans; Male; Middle Aged; Migraine Disorders

1976
Migraine in childhood. A review.
    Clinical pediatrics, 1979, Volume: 18, Issue:6

    Topics: Acute Disease; Age Factors; Anticonvulsants; Child; Child, Preschool; Clonidine; Ergotamines; Female

1979
Effects of acute hypotension and hypertension on serum TSH concentrations in male rats.
    Acta physiologica Scandinavica, 1979, Volume: 107, Issue:2

    Topics: Acute Disease; Angiotensin II; Animals; Clonidine; Dihydralazine; Hypertension; Hypotension; Male; N

1979
Withdrawal of antihypertensive therapy. Hypertensive crisis in renovascular hypertension.
    JAMA, 1977, Oct-17, Volume: 238, Issue:16

    Topics: Acute Disease; Aged; Blood Pressure; Clonidine; Diuretics; Female; Humans; Hypertension, Malignant;

1977
[Therapy of hypertensive crisis].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine

1977
[Therapy of hypertensive crises].
    Fortschritte der Medizin, 1977, Apr-21, Volume: 95, Issue:15

    Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine

1977
Acute postoperative clonidine withdrawal syndrome.
    Anesthesiology, 1976, Volume: 44, Issue:6

    Topics: Acute Disease; Clonidine; Humans; Male; Middle Aged; Postoperative Complications; Substance Withdraw

1976
Clonidine treatment of acute pancreatitis: report of five cases.
    Acta gastroenterologica Latinoamericana, 1992, Volume: 22, Issue:2

    Topics: Acute Disease; Adult; Blood Pressure; Clonidine; Epinephrine; Female; Follow-Up Studies; Growth Horm

1992
Dramatic improvement with clonidine in acute pancreatitis with elevated catecholamine and cortisol plasma levels: report of five cases.
    Journal of medicine, 1992, Volume: 23, Issue:5

    Topics: Acute Disease; Adult; Catecholamines; Clonidine; Female; Humans; Hydrocortisone; Male; Pancreatitis

1992
The growth hormone response to clonidine in acute and remitted depressed male patients.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1992, Volume: 6, Issue:3

    Topics: Acute Disease; Adult; Aged; Analysis of Variance; Clonidine; Depressive Disorder; Growth Hormone; Hu

1992
Clonidine in the treatment of alcohol withdrawal in the intensive care unit.
    British journal of anaesthesia, 1992, Volume: 68, Issue:1

    Topics: Acute Disease; Aged; Clonidine; Colectomy; Critical Care; Ethanol; Humans; Male; Middle Aged; Multip

1992
[Acute klofelin poisoning].
    Klinicheskaia meditsina, 1990, Volume: 68, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Antidotes; Atropine; Benzilates; Bradycardia; Child, Preschool; Ch

1990
Head injury: clonidine decreases plasma catecholamines.
    Critical care medicine, 1990, Volume: 18, Issue:4

    Topics: Acute Disease; Adult; Blood Flow Velocity; Brain Injuries; Carotid Arteries; Cerebrovascular Circula

1990
Use of apraclonidine in the treatment of acute angle closure glaucoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:9

    Topics: Acute Disease; Clonidine; Female; Glaucoma, Angle-Closure; Humans

1990
Alpha-adrenoceptor function in acute paranoid schizophrenia.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:6

    Topics: Acute Disease; Adrenocorticotropic Hormone; Adult; Clonidine; Female; Growth Hormone; Humans; Hydroc

1988
Severe hypotension associated with concurrent clonidine and antipsychotic medication.
    The American journal of psychiatry, 1985, Volume: 142, Issue:2

    Topics: Acute Disease; Aged; Antipsychotic Agents; Chlorpromazine; Clonidine; Drug Interactions; Drug Therap

1985
[Idiopathic localized paroxysmal hyperhidrosis. Treatment with clonidine].
    Revue neurologique, 1986, Volume: 142, Issue:8-9

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adult; Clonidine; Female; Follow-Up Studies; Humans; Hyper

1986
Clonidine in the treatment of Tourette's syndrome exacerbation due to haloperidol withdrawal.
    The Journal of nervous and mental disease, 1986, Volume: 174, Issue:4

    Topics: Acute Disease; Adult; Clonidine; Haloperidol; Humans; Male; Substance Withdrawal Syndrome; Tourette

1986
[Acute gemiton poisonings in children].
    Pediatriia, 1987, Issue:9

    Topics: Acute Disease; Adolescent; Blood Volume; Child; Child, Preschool; Clonidine; Diagnosis; Hemodynamics

1987
[Hyperglycemia and arterial hypertension on severe acute hepatic insufficiency].
    Revista espanola de las enfermedades del aparato digestivo, 1985, Volume: 68, Issue:1

    Topics: Acute Disease; Clonidine; Female; Hepatitis, Viral, Human; Humans; Hyperglycemia; Hypertension; Insu

1985
Acute colonic pseudo-obstruction: a possible role for the colocolonic reflex.
    Journal of clinical gastroenterology, 1985, Volume: 7, Issue:3

    Topics: Acute Disease; Anesthesia, Epidural; Clonidine; Colonic Diseases; Colonic Diseases, Functional; Fema

1985
Management of acute hypertensive crises with clonidine (Catapres).
    The Medical journal of Australia, 1974, May-25, Volume: 1, Issue:21

    Topics: Acute Disease; Adult; Aged; Blood Pressure; Clonidine; Female; Humans; Hypertension; Injections, Int

1974
[Pathogenesis and therapy of acute pulmonary edema].
    Il Policlinico. Sezione pratica, 1972, Jan-01, Volume: 79, Issue:1

    Topics: Acute Disease; Brain Diseases; Cardiac Glycosides; Clonidine; Diuretics; Gas Poisoning; Heart Defect

1972