Page last updated: 2024-10-25

clonidine and Acathisia, Drug-Induced

clonidine has been researched along with Acathisia, Drug-Induced in 14 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Research Excerpts

ExcerptRelevanceReference
"A comprehensive literature search was conducted to identify clinical trials that observed the effect of midazolam and clonidine on preventing EA in children after their emergence from sevoflurane anesthesia."8.89Prophylactic midazolam and clonidine for emergence from agitation in children after emergence from sevoflurane anesthesia: a meta-analysis. ( Li, J; Wang, Y; Zhang, C; Zhao, D, 2013)
"A comprehensive literature search was conducted to identify clinical trials that observed the effect of midazolam and clonidine on preventing EA in children after their emergence from sevoflurane anesthesia."4.89Prophylactic midazolam and clonidine for emergence from agitation in children after emergence from sevoflurane anesthesia: a meta-analysis. ( Li, J; Wang, Y; Zhang, C; Zhao, D, 2013)
"2) treatment on the withdrawal symptoms associated with smoking cessation."2.66Effects of transdermal clonidine treatment on withdrawal symptoms associated with smoking cessation. A randomized, controlled trial. ( McAdams, LA; Ornish, SA; Zisook, S, 1988)
"Propofol was effective when used throughout anaesthesia (RR 0."2.50Effects of sevoflurane versus other general anaesthesia on emergence agitation in children. ( Ahmed, S; Burgoyne, LL; Chooi, C; Costi, D; Cyna, AM; Ellwood, J; Larsson, JN; Middleton, P; Stephens, K; Strickland, P, 2014)
"Evidence on the treatment of tardive akathisia is unsatisfactory."2.41Managing antipsychotic-induced acute and chronic akathisia. ( Fleischhacker, WW; Miller, CH, 2000)
"Two cases of tardive akathisia, which were misdiagnosed as anxiety originating from a schizophrenic disorder, had been treated with anxiolytics in addition to neuroleptics and anticholinergics."1.28Treatment of tardive akathisia with clonidine. ( Koga, I; Nishikawa, T; Tanaka, M; Uchida, Y, 1990)
"Six patients with akathisia were treated with clonidine in an open, on-drug/off-drug trial."1.27Use of clonidine in treating neuroleptic-induced akathisia. ( Cohen, BM; Jonas, JM; Lipinski, JF; Zubenko, GS, 1984)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's2 (14.29)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tan, D1
Xia, H1
Sun, S1
Wang, F1
Zhang, C1
Li, J1
Zhao, D1
Wang, Y1
Costi, D1
Cyna, AM1
Ahmed, S1
Stephens, K1
Strickland, P1
Ellwood, J1
Larsson, JN1
Chooi, C1
Burgoyne, LL1
Middleton, P1
Bock, M1
Kunz, P1
Schreckenberger, R1
Graf, BM1
Martin, E1
Motsch, J1
Lankinen, U1
Avela, R1
Tarkkila, P1
Zubenko, GS1
Cohen, BM1
Lipinski, JF1
Jonas, JM1
Miller, CH1
Fleischhacker, WW1
Sachdev, P1
Chee, KY1
Nishikawa, T1
Koga, I1
Uchida, Y1
Tanaka, M1
Sandyk, R1
Adler, LA1
Angrist, B2
Peselow, E2
Reitano, J1
Rotrosen, J2
Adler, L1
Corwin, J1
Khot, V1
Goodwin, J1
Wandry, G1
Ornish, SA1
Zisook, S1
McAdams, LA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Emergence Delirium in Children: a Randomized Clinical Trial of Different Doses of Sevoflurane During Induction of Anesthesia[NCT02707016]80 participants (Anticipated)Interventional2015-12-31Recruiting
Investigation of the DNA Methylation Profile in Children Who Presented Emergence Delirium[NCT03787849]175 participants (Actual)Interventional2018-09-24Completed
Effect of Single-dose Dexmedetomidine on Emergence Agitation and Postoperative Behavior Changes After Sevoflurane Anesthesia in Children[NCT03596775]Early Phase 196 participants (Anticipated)Interventional2018-09-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for clonidine and Acathisia, Drug-Induced

ArticleYear
Effect of ancillary drugs on sevoflurane related emergence agitation in children undergoing ophthalmic surgery: a Bayesian network meta-analysis.
    BMC anesthesiology, 2019, 08-01, Volume: 19, Issue:1

    Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Bayes Theo

2019
Prophylactic midazolam and clonidine for emergence from agitation in children after emergence from sevoflurane anesthesia: a meta-analysis.
    Clinical therapeutics, 2013, Volume: 35, Issue:10

    Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous;

2013
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Managing antipsychotic-induced acute and chronic akathisia.
    Drug safety, 2000, Volume: 22, Issue:1

    Topics: Acute Disease; Akathisia, Drug-Induced; Amantadine; Antipsychotic Agents; Benzodiazepines; Cholinerg

2000

Trials

5 trials available for clonidine and Acathisia, Drug-Induced

ArticleYear
Comparison of caudal and intravenous clonidine in the prevention of agitation after sevoflurane in children.
    British journal of anaesthesia, 2002, Volume: 88, Issue:6

    Topics: Adrenergic alpha-Agonists; Akathisia, Drug-Induced; Analgesics; Anesthetics, Inhalation; Child; Chil

2002
The prevention of emergence agitation with tropisetron or clonidine after sevoflurane anesthesia in small children undergoing adenoidectomy.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:5

    Topics: Adenoidectomy; Akathisia, Drug-Induced; Anesthesia, Inhalation; Chi-Square Distribution; Child; Chil

2006
Pharmacological characterization of tardive akathisia.
    Biological psychiatry, 1990, Nov-01, Volume: 28, Issue:9

    Topics: Administration, Oral; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Atenolol; Benztr

1990
Noradrenergic mechanisms in akathisia: treatment with propranolol and clonidine.
    Psychopharmacology bulletin, 1987, Volume: 23, Issue:1

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Clonidine; Female; Humans; Male; Middle Aged;

1987
Effects of transdermal clonidine treatment on withdrawal symptoms associated with smoking cessation. A randomized, controlled trial.
    Archives of internal medicine, 1988, Volume: 148, Issue:9

    Topics: Acute Disease; Administration, Cutaneous; Adult; Akathisia, Drug-Induced; Analysis of Variance; Anxi

1988

Other Studies

5 other studies available for clonidine and Acathisia, Drug-Induced

ArticleYear
Use of clonidine in treating neuroleptic-induced akathisia.
    Psychiatry research, 1984, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Anxiety Disorders; Bipolar D

1984
Treatment of tardive akathisia with clonidine.
    The Kurume medical journal, 1990, Volume: 37, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Anxiety; Clonidine; Diagnosis, Differential; H

1990
Antimanic effects of clonidine and the endogenous opioid system.
    The American journal of psychiatry, 1985, Volume: 142, Issue:8

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Bipolar Disorder; Brain; Clonidine; Endorphins; Human

1985
Clonidine in neuroleptic-induced akathisia.
    The American journal of psychiatry, 1987, Volume: 144, Issue:2

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Anxiety; Clonidine; Hospitalization; Humans; M

1987
Time course of effects of clonidine.
    The American journal of psychiatry, 1987, Volume: 144, Issue:11

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Clonidine; Dyskinesia, Drug-Induced; Humans; Psychomo

1987