Page last updated: 2024-10-25

clonidine and Abdominal Migraine

clonidine has been researched along with Abdominal Migraine in 91 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Research Excerpts

ExcerptRelevanceReference
"The efficacies of an 2-agonist clonidine and an 2-antagonist mianserin were compared in two treatment groups, common migraine and tension headache sufferers."5.05Headache and noradrenergic involvement: the effects of alpha 2-stimulants and alpha 2-antagonists. ( Agnoli, A; Denaro, A; Manna, V; Martucci, N; Ruggieri, S, 1985)
" For hemicrania we used cinnarizine, cyproheptadine, clonidine, histamine, pizotifene and reserpine; for cluster headache, cinnarizine, cyproheptadine, clonidine, histamine and reserpine; for tension headache, cyproheptadine; for psychogenic headache, allylpropylmalonylurea."5.04[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)]. ( Agostoni, A; Brandi, G; Cottino, A; Gai, V; Gastaldi, L; Lisino, F; Nattero, G, 1975)
"Baclofen, tizanidine and botulinum toxin A, agents used to treat disorders of muscle tone, have been studied as potential preventative treatments for migraine, tension-type headache and other related disorders."4.82Preventative treatment for migraine and tension-type headaches : do drugs having effects on muscle spasm and tone have a role? ( Freitag, FG, 2003)
" In order to elucidate the relationship between noradrenergic and opioidergic functions, the plasma beta-endorphin (beta-EP) response to clonidine and the cortisol response to dexamethasone were evaluated together in 25 patients suffering from migraine without aura, and with chronic tension headache (MTH)."3.67Neuroendocrine evidence of deranged noradrenergic activity in chronic migraine. ( Facchinetti, F; Genazzani, AR; Martignoni, E; Nappi, G; Rossi, F; Sances, G, 1989)
" The dosage of metoprolol was 50 mg b."2.66Metoprolol v. clonidine in the prophylactic treatment of migraine. ( Hedman, C; Louis, P; Schoenen, J, 1985)
" The daily dosage of propranolol and clonidine was 160 mg and 100 microgram, respectively."2.65Propranolol (Inderal) and clonidine (Catapressan) in the prophylactic treatment of migraine. A comparative trial. ( Kåss, B; Nestvold, K, 1980)
"Various drugs have been used in migraine to bring down the frequency of attacks."2.65Clonidine in prophylaxis of migraine. ( Ahuja, GK; Das, SM; Narainaswamy, AS, 1979)
"The prophylactic effect of clonidine in a dosage of 0."2.64Clonidine in the prophylaxis of migraine. ( Boisen, E; Deth, S; Hübbe, P; Jansen, J; Klee, A; Leunbach, G, 1978)
"Clonidine and placebo were given for 7 weeks each, but only the last 5 weeks in each period were used for the statistical evaluation."2.64Clonidine (Catapresan)-double-blind study after long-term treatment with the drug in migraine. ( Sjaastad, O; Stensrud, P, 1976)
"Clonidine was the most frequently prescribed (49."1.42Prescribing patterns of anti-migraine medicines in South Africa using a claims database. ( Truter, I, 2015)
"Chronic migraine is an important public health problem."1.36Pharmacological prophylaxis of chronic migraine: a review of double-blind placebo-controlled trials. ( D'Amico, D, 2010)
"Usage patterns of specific migraine prophylactic drugs were evaluated for each patient by accessing data from a large prescription database and were characterized as continued, switch or stop use during the patient observation period."1.32Migraine prophylactic medication usage patterns in The Netherlands. ( Buurma, H; Egberts, AC; Leufkens, HG; Rahimtoola, H; Tijssen, CC, 2003)
" A marked suppressive effect on cortisol secretion was observed in the migrainous patients after acute and chronic administration of clonidine."1.27Basal plasma HGH and cortisol levels and the effect of clonidine administration in female migrainous patients. ( Bechar, M; Gil-Ad, I; Hering, R; Laron, Z; Tyano, S; Weizman, A; Weizman, R, 1984)
"Patients having one or more attacks of migraine a week may need prophylactic treatment."1.26[The use of drugs in migraine]. ( Wilkinson, M, 1976)
" The therapeutic cycles were standardized, for each drug, in the way of administration, dosage and total duration of the treatment."1.26[Therapeutic possibilities in idiopathic headaches. Analysis of about 1000 cases]. ( Agostoni, A; Brandi, G; Cottino, A; Gai, V; Gastaldi, L; Lisino, F; Nattero, G, 1976)
"Three of the migraine subjects had raised basal plasma noradrenaline levels but all had been taking clonidine up to 12-24 hr before the test and the increased plasma noradrenaline levels were probably due to the effect of withdrawal of the drug."1.26The metabolic and hormonal response to glucagon. Part 2. In patients with migraine. ( Capildeo, R; Goodwin, PM; Harrop, JS; Marks, V; Rose, FC, 1976)
"The demonstration that long-term administration of relatively low doses of clonidine decreased the responsiveness of blood vessels to vasodilator and vasoconstrictor drugs in animals led to its investigation in the prevention of migraine in man."1.25Low-dose clonidine: a review of its therapeutic efficacy in migraine prophylaxis. ( Avery, GS; Brogden, RN; Pinder, RM; Sawyer, PR; Speight, TM, 1975)

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-199078 (85.71)18.7374
1990's6 (6.59)18.2507
2000's5 (5.49)29.6817
2010's2 (2.20)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Truter, I1
D'Amico, D1
Freitag, FG1
Rahimtoola, H1
Buurma, H1
Tijssen, CC1
Leufkens, HG1
Egberts, AC1
Ignatov, IuD1
Skoromets, AA1
Amelin, AV1
Rapoport, AM1
Bigal, ME1
Richter, F1
Mikulik, O1
Ebersberger, A1
Schaible, HG1
Agnoli, A3
Denaro, A2
Ceci, E1
Falaschi, P1
Johnson, JM1
Sills, M1
Congdon, P1
Forsythe, I1
Sicuteri, F1
Centonze, V1
Brucoli, C1
Attolini, E1
Macinagrossa, G1
Sabbà, C1
Campanozzi, F1
Albano, O1
Wood, J1
Lance, J1
Weizman, A1
Gil-Ad, I1
Weizman, R1
Hering, R1
Bechar, M1
Tyano, S1
Laron, Z1
Lian, QS1
Ambielli, M1
Kåss, B1
Nestvold, K1
Hakkarainen, H2
Kokkanen, E1
Kallanranta, T2
Mylecharane, EJ2
Duckworth, JW2
Lord, GD2
Lance, JW4
Diamond, S2
Medina, JL1
Hermann, C1
Kim, M1
Blanchard, EB1
Wiedemann, M1
de Lima, VM1
Hanke, W1
Meyer, C1
Shtok, VN1
Pigarev, VA1
Fanchamps, A2
Pozniak-Patewicz, E1
Glover, V1
Sandler, M1
Grant, E1
Rose, FC2
Orton, D1
Wilkinson, M4
Stevens, D1
Wahlberg, P1
Spira, PJ1
Fozard, JR1
Sillanpää, M1
Mondrup, K1
Moller, CE1
Boisen, E2
Deth, S1
Hübbe, P1
Jansen, J1
Klee, A2
Leunbach, G1
Adam, EI1
Gore, SM1
Price, WH1
Wood, RA1
Das, SM1
Ahuja, GK1
Narainaswamy, AS1
Barolin, GS1
Congdon, PJ1
Forsythe, WI1
Hackaday, J1
Isler, H1
Critchley, EM1
Stensrud, P2
Sjaastad, O2
Nattero, G2
Agostoni, A2
Brandi, G2
Cottino, A2
Gai, V2
Gastaldi, L2
Lisino, F2
Damato, H1
Hokkanen, E1
Tuovinen, T1
Ryan, RE6
Lynggaard, F1
Ostergaard, F1
White, G1
Munro, J1
Coote, NP1
Brogden, RN1
Pinder, RM1
Sawyer, PR1
Speight, TM1
Avery, GS1
Corbat, F1
Goodwin, PM1
Capildeo, R1
Harrop, JS1
Marks, V1
Callaghan, N1
Green, C1
Horowitz, I1
Martignoni, E2
Facchinetti, F2
Rossi, F1
Sances, G2
Genazzani, AR2
Nappi, G2
Bredfeldt, RC1
Sutherland, JE1
Kruse, JE1
Massiou, H1
Bousser, MG1
Prusiński, A1
Petraglia, F1
Manzoni, GC1
Sandrini, G1
Martucci, N2
Manna, V2
Porto, C1
Louis, P1
Schoenen, J1
Hedman, C1
Ruggieri, S1
Frewin, DB1
Rozniecki, J1
Durward, WF1
Shafar, J2
Tallett, ER2
Knowlson, PA2
Nurick, S1
Pollard, PA1
Wall, MC2
Saxena, PR1
de Vlaam-Schluter, GM1
Anthony, M2
Somerville, B1
Sharpe, CJ1
Heathfield, KW1
Raiman, JD1
Patten, JP1
Levens, LK1
Hanington, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness of Onabotulinumtoxin A (Botox) in Pediatric Patients Experiencing Migraines: A Randomized Double Blinded Placebo Cross-over Study in the Pediatric Pain Population[NCT03055767]Phase 217 participants (Actual)Interventional2017-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

"Duration of Migraine

Open-Label Period" (NCT03055767)
Timeframe: Duration of migraine in hours during the open-label period (2 additional rounds of onabotulinumtoxinA) as compared to the cross-over period.

InterventionDuration of migraine in hours during the open-labe (hours)
Cross-Over PeriodMedian
"Open-Label Period Median

"Frequency of Migraines

Open-label Period" (NCT03055767)
Timeframe: The frequency of migraines during the open-label period (2 additional rounds of onabotulinumtoxinA) as compared to the cross-over period.

InterventionThe frequency of migraines during the open-label p (days)
"Open-Label Period Median

"Intensity of Migraines

Open-Label Period" (NCT03055767)
Timeframe: "Intensity of migraines during the the open-label period (2 additional rounds of onabotulinumtoxinA) as compared to the cross-over period.~Intensity based on 0-10 Pain Numeric Rating Score (NRS). The higher the score, the more intense the pain."

Intervention"Intensity of migraines during the the open-label (units on a scale)
Cross-Over PeriodMedian
"Open-Label Period Median

"Pediatric Migraine Disability Score (PedMIDAS)

Open-Label Period" (NCT03055767)
Timeframe: "The PedMIDAS the open-label period (2 additional rounds of onabotulinumtoxinA) as compared to the cross-over period.~The PedMIDAS consists of 6 questions: 3 addressing school attendance and functioning, and 3 evaluating participation in events outside of

Intervention"The PedMIDAS the open-label period (2 additional (score on a scale)
Cross-Over PeriodMedian
"Open-Label Period Median

Concomitant Headache Medications

Number of concomitant headache medications taken (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

Interventionnumber taken (Median)
"Baseline Period 3
Botox Period1
Placebo Period2

Difficulty Sleeping

Subject reported having difficulty sleeping (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

InterventionParticipants (Count of Participants)
"Baseline Period 12
Botox Period5
Placebo Period11

Duration of Benefit

The duration of benefit in weeks (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

Interventionweeks (Median)
Botox Period4
Placebo Period0

Emergency Department (ED) Visits

Subject visited an Emergency Department (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

InterventionParticipants (Count of Participants)
"Baseline Period 8
Botox Period2
Placebo Period3

Frequency of Migraines

The frequency of migraines in days. (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

Interventiondays (Median)
"Baseline Period 28
Botox Period20
Placebo Period28

Functionality Improvement

"Improvement of functionality as determined by their Pediatric Migraine Disability Score (PedMIDAS). The PedMIDAS consists of 6 questions: 3 addressing school attendance and functioning, and 3 evaluating participation in events outside of school. The questionnaire is based on the patient's recall of the previous 3 months.~The questionnaire produces a raw score (0-10, 11-30, 31-50, >50) corresponding to a disability grade with increasing severity (little to non, mild, moderate, and severe) which was coded (1, 2, 3, and 4)." (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

Interventionscore on a scale (Median)
Botox Period1
Placebo Period0

Home School

Subject is home schooled full-time. (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post, respective intervention

InterventionParticipants (Count of Participants)
"Baseline Period 2
Botox Period2
Placebo Period2

Hospital Admissions

Admission to hospital (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

InterventionParticipants (Count of Participants)
"Baseline Period 8
Botox Period0
Placebo Period2

Intensity of Migraines

Median intensity of migraines based on 0-10 Pain Numeric Rating Score (NRS). The higher the score, the more intense the pain. (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

Interventionunits on a scale (Median)
"Baseline Period 8
Botox Period5
Placebo Period7

Migraine Duration, in Hours

Duration of migraines in hours. (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

Interventionhours (Median)
"Baseline Period 24
Botox Period10
Placebo Period24

Pediatric Migraine Disability Score (PedMIDAS)

"Pediatric Migraine Disability Score consists of 6 questions: 3 addressing school attendance and functioning, and 3 evaluating participation in events outside of school. The questionnaire is based on the patient's recall of the previous 3 months.~The questionnaire produces a raw score (0-10, 11-30, 31-50, >50) corresponding to a disability grade with increasing severity (little to non, mild, moderate, and severe) which was coded (1, 2, 3, and 4)." (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

Interventionscore on a scale (Median)
"Baseline Period 4
Botox Period3
Placebo Period4

School Plan Enrollment

Subject is enrolled in a school plan such as IEP, 504 plan, or similar modified school schedule. (NCT03055767)
Timeframe: Baseline (4 weeks) and 12 weeks post each, respective intervention

InterventionParticipants (Count of Participants)
"Baseline Period 11
Botox Period10
Placebo Period10

Reviews

15 reviews available for clonidine and Abdominal Migraine

ArticleYear
Preventative treatment for migraine and tension-type headaches : do drugs having effects on muscle spasm and tone have a role?
    CNS drugs, 2003, Volume: 17, Issue:6

    Topics: Baclofen; Botulinum Toxins, Type A; Clonidine; GABA Agonists; Humans; Migraine Disorders; Muscle Rel

2003
[Current views on migraine and anti-migraine preparations].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2003, Issue:10

    Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics; Analgesics, No

2003
Preventive migraine therapy: what is new.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2004, Volume: 25 Suppl 3

    Topics: Analgesics; Angiotensin-Converting Enzyme Inhibitors; Antidepressive Agents, Second-Generation; Anti

2004
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic;

1984
The role of clonidine in the treatment of migraine: a review of the literature and personal experience.
    Upsala journal of medical sciences. Supplement, 1980, Volume: 31

    Topics: Age Factors; Clinical Trials as Topic; Clonidine; Double-Blind Method; Humans; Migraine Disorders; P

1980
Behavioral and prophylactic pharmacological intervention studies of pediatric migraine: an exploratory meta-analysis.
    Pain, 1995, Volume: 60, Issue:3

    Topics: Behavioral Medicine; Biofeedback, Psychology; Child; Clonidine; Dopamine Agents; Humans; Migraine Di

1995
[Treatment of migraine].
    Klinicheskaia meditsina, 1979, Volume: 57, Issue:12

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Analgesics; Antidepressive Agents, Tricyclic; Cinnar

1979
The animal pharmacology of drugs used in the treatment of migraine.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:5

    Topics: Acetaminophen; Adrenergic alpha-Antagonists; Analgesics; Animals; Aspirin; Caffeine; Clonidine; Cypr

1975
[Classification, pathogenesis and drug therapy of migraine and related forms of headache].
    Die Medizinische Welt, 1975, Aug-29, Volume: 6, Issue:35

    Topics: Adrenergic beta-Antagonists; Animals; Caffeine; Clonidine; Dihydroergotamine; Drug Synergism; Epinep

1975
The therapeutic uses of clonidine.
    Scottish medical journal, 1979, Volume: 24, Issue:3

    Topics: Blood Pressure; Climacteric; Clonidine; Female; Glaucoma; Hemodynamics; Humans; Hypertension; Kidney

1979
Monotherapy or polytherapy in migraine.
    Neuroepidemiology, 1987, Volume: 6, Issue:4

    Topics: Barbiturates; Clonidine; Dihydroergotamine; Drug Combinations; Humans; Migraine Disorders; Pizotylin

1987
Role of some biogenic substances in migraine and relevant mechanism in antimigraine action of ergotamine--studies in an experimental model for migraine.
    Headache, 1974, Volume: 13, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Blood Pressure; Bradykinin; Carotid Arteries

1974
Current concepts in the pathogenesis and interval treatment of migraine.
    Drugs, 1972, Volume: 3, Issue:3

    Topics: Adrenergic beta-Antagonists; Bradykinin; Clonidine; Cycloheptanes; Cyproheptadine; Ergotamine; Hista

1972
[Clonidine (Catapresan) in prevention of migraine].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Nov-30, Volume: 93, Issue:33

    Topics: Clonidine; Depression; Fatigue; Humans; Migraine Disorders; Placebos; Time Factors

1973
Migraine.
    Transactions of the Medical Society of London, 1971, Volume: 87

    Topics: Blood Vessels; Cacao; Cheese; Clonidine; Diet Therapy; Eye Diseases; Food; Headache; Hematologic Dis

1971

Trials

24 trials available for clonidine and Abdominal Migraine

ArticleYear
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic;

1984
Clonidine and childhood migraine: a pilot and double-blind study.
    Developmental medicine and child neurology, 1982, Volume: 24, Issue:6

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Eruptions; F

1982
[Therapy of migraine crises: experience with clonidine].
    La Clinica terapeutica, 1983, Jul-15, Volume: 106, Issue:1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Clonidine; Drug Evaluation; Female; Humans; Male; Middl

1983
Clonidine and migraine.
    The Medical journal of Australia, 1984, Mar-17, Volume: 140, Issue:6

    Topics: Clinical Trials as Topic; Clonidine; Humans; Migraine Disorders

1984
Propranolol (Inderal) and clonidine (Catapressan) in the prophylactic treatment of migraine. A comparative trial.
    Acta neurologica Scandinavica, 1980, Volume: 61, Issue:6

    Topics: Adult; Clinical Trials as Topic; Clonidine; Double-Blind Method; Ergotamine; Female; Humans; Male; M

1980
The role of clonidine in the treatment of migraine: a review of the literature and personal experience.
    Upsala journal of medical sciences. Supplement, 1980, Volume: 31

    Topics: Age Factors; Clinical Trials as Topic; Clonidine; Double-Blind Method; Humans; Migraine Disorders; P

1980
Clonidine prophylaxis of childhood migraine and other vascular headache. A double blind study of 57 children;.
    Headache, 1977, Volume: 17, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Clonidine; Female; Headache; Humans;

1977
Prophylactic treatment of migraine with clonidine. A controlled clinical trial.
    Acta neurologica Scandinavica, 1977, Volume: 56, Issue:5

    Topics: Adolescent; Adult; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Evaluation; Female

1977
Clonidine in the prophylaxis of migraine.
    Acta neurologica Scandinavica, 1978, Volume: 58, Issue:5

    Topics: Adult; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Evaluation; Female; Humans; Ma

1978
Double blind trial of clonidine in the treatment of migraine in a general practice.
    The Journal of the Royal College of General Practitioners, 1978, Volume: 28, Issue:195

    Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Clonidine; Double-Blind Method; Family Pra

1978
Clonidine in prophylaxis of migraine.
    Acta neurologica Scandinavica, 1979, Volume: 60, Issue:4

    Topics: Adult; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged;

1979
Clonidine (Catapresan)-double-blind study after long-term treatment with the drug in migraine.
    Acta neurologica Scandinavica, 1976, Volume: 53, Issue:3

    Topics: Adult; Clinical Trials as Topic; Clonidine; Drug Evaluation; Female; Humans; Male; Middle Aged; Migr

1976
[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1975, Sep-19, Volume: 117, Issue:38

    Topics: Aspirin; Caffeine; Cinnarizine; Clinical Trials as Topic; Clonidine; Cyproheptadine; Drug Therapy, C

1975
Clonidine--its use in migraine therapy.
    Headache, 1975, Volume: 14, Issue:4

    Topics: Adult; Clinical Trials as Topic; Clonidine; Female; Humans; Male; Middle Aged; Migraine Disorders

1975
[Clonidine in prevention of migraine. Report of a double-blind study of 38 patients referred for neurological assessment].
    Ugeskrift for laeger, 1975, Jan-13, Volume: 137, Issue:3

    Topics: Adolescent; Adult; Clinical Trials as Topic; Clonidine; Drug Evaluation; Female; Humans; Male; Middl

1975
Double blind study of clonidine and placebo for the prophylactic treatment of migraine.
    Headache, 1975, Volume: 15, Issue:3

    Topics: Clinical Trials as Topic; Clonidine; Female; Humans; Male; Migraine Disorders; Placebos

1975
[Clonidin in the treatment of migraine (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1976, Jan-20, Volume: 65, Issue:3

    Topics: Blood Vessels; Clonidine; Drug Antagonism; Humans; Migraine Disorders; Vasoconstrictor Agents; Vasod

1976
Efficacy of transdermal clonidine for headache prophylaxis and reduction of narcotic use in migraine patients. A randomized crossover trial.
    The Journal of family practice, 1989, Volume: 29, Issue:2

    Topics: Administration, Cutaneous; Adult; Clinical Trials as Topic; Clonidine; Data Collection; Double-Blind

1989
Migraine and the noradrenergic control of vasomotricity: a study with alpha-2 stimulant and alpha-2 blocker drugs.
    Headache, 1985, Volume: 25, Issue:2

    Topics: Adult; Clinical Trials as Topic; Clonidine; Dibenzazepines; Double-Blind Method; Female; Headache; H

1985
Metoprolol v. clonidine in the prophylactic treatment of migraine.
    Cephalalgia : an international journal of headache, 1985, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Clonidine; Double-Blind Method

1985
Headache and noradrenergic involvement: the effects of alpha 2-stimulants and alpha 2-antagonists.
    Acta psychiatrica Scandinavica. Supplementum, 1985, Volume: 320

    Topics: Adult; Clinical Trials as Topic; Clonidine; Dibenzazepines; Double-Blind Method; Female; Headache; H

1985
Evaluation of clonidine in prophylaxis of migraine. Double-blind trial and follow-up.
    Lancet (London, England), 1972, Feb-19, Volume: 1, Issue:7747

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Female; Follo

1972
Clonidine for migraine.
    Drug and therapeutics bulletin, 1972, Jul-21, Volume: 10, Issue:15

    Topics: Clinical Trials as Topic; Clonidine; Humans; Migraine Disorders

1972
Preliminary report on the use of clonidine (Boehringer Ingelheim) in the treatment of migraine.
    Research and clinical studies in headache, 1970, Volume: 3

    Topics: Adult; Clinical Trials as Topic; Clonidine; Evaluation Studies as Topic; Female; Humans; Male; Middl

1970

Other Studies

54 other studies available for clonidine and Abdominal Migraine

ArticleYear
Prescribing patterns of anti-migraine medicines in South Africa using a claims database.
    International journal of clinical pharmacy, 2015, Volume: 37, Issue:3

    Topics: Adult; Clonidine; Databases, Factual; Drugs, Generic; Female; Humans; Insurance, Health, Reimburseme

2015
Pharmacological prophylaxis of chronic migraine: a review of double-blind placebo-controlled trials.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2010, Volume: 31 Suppl 1

    Topics: Amines; Analgesics; Chronic Disease; Clonidine; Cyclohexanecarboxylic Acids; Diagnosis, Differential

2010
Migraine prophylactic medication usage patterns in The Netherlands.
    Cephalalgia : an international journal of headache, 2003, Volume: 23, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Analgesics; Calcium Channel Blockers; Clonidine; Drug Combinatio

2003
Noradrenergic agonists and antagonists influence migration of cortical spreading depression in rat-a possible mechanism of migraine prophylaxis and prevention of postischemic neuronal damage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2005, Volume: 25, Issue:9

    Topics: Adrenergic alpha-Agonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Animals; Blood Press

2005
On the etiopathogenesis of migraine: a possible link between the amines and endorphin hypotheses.
    Advances in neurology, 1982, Volume: 33

    Topics: Adult; Clonidine; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Histamine; Huma

1982
Inhibition of peptidase degrading endogenous opioids: a new trend in the management of migraine and correlated "pain diseases".
    Advances in experimental medicine and biology, 1983, Volume: 156 (Pt B)

    Topics: Brain; Captopril; Clonidine; Cluster Headache; Endorphins; Humans; Migraine Disorders; Nociceptors;

1983
Basal plasma HGH and cortisol levels and the effect of clonidine administration in female migrainous patients.
    Neuropsychobiology, 1984, Volume: 12, Issue:2-3

    Topics: Adolescent; Adult; Clonidine; Female; Follow-Up Studies; Growth Hormone; Humans; Hydrocortisone; Mig

1984
[Pharmacology of clonidine and its clinical application].
    Sheng li ke xue jin zhan [Progress in physiology], 1983, Volume: 14, Issue:2

    Topics: Animals; Blood Pressure; Brain; Clonidine; Humans; Hypertension; Migraine Disorders; Opioid-Related

1983
Drug stop: migraine headache. Current therapy.
    Journal of neurosurgical nursing, 1982, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Child; Clonidine; Diet; Ergot Alkaloids; Female; Humans; Male; Middle Aged; Migra

1982
Effects of low doses of clonidine in the monkey cranial circulation.
    European journal of pharmacology, 1980, Nov-21, Volume: 68, Issue:2

    Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Clonidine; Dose-Response Relationship, Drug; H

1980
Newer drug therapies for headache.
    Postgraduate medicine, 1980, Volume: 68, Issue:1

    Topics: Antidepressive Agents; Aspirin; Bromocriptine; Clonidine; Cluster Headache; Dipyridamole; Headache;

1980
Effects of antimigraine drugs on retinal spreading depression.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:5

    Topics: Acetaminophen; Adrenergic beta-Antagonists; Adrenochrome; Analgesics, Non-Narcotic; Animals; Aspirin

1996
[Treatment of migraine (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1975, Feb-25, Volume: 64, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents; Caffeine; Child; Clonidine; Drug Therapy,

1975
[Mechanism of action of drugs currently used in the prevention of migraine].
    Minerva medica, 1976, Jun-02, Volume: 67, Issue:28

    Topics: Adrenergic beta-Antagonists; Catecholamines; Cerebrovascular Circulation; Chemical Phenomena; Chemis

1976
Clonidine in acute migraine.
    Lancet (London, England), 1976, Oct-30, Volume: 2, Issue:7992

    Topics: Acute Disease; Adult; Clonidine; Female; Humans; Male; Middle Aged; Migraine Disorders

1976
Transitory decrease in platelet monoamine-oxidase activity during migraine attacks.
    Lancet (London, England), 1977, Feb-19, Volume: 1, Issue:8008

    Topics: Adolescent; Adult; Aspirin; Blood Platelets; Blood Proteins; Child; Child, Preschool; Clonidine; Dia

1977
Two types of migraine.
    Lancet (London, England), 1979, Jan-20, Volume: 1, Issue:8108

    Topics: Adrenergic beta-Antagonists; Clonidine; Humans; Migraine Disorders; Temperature

1979
Evaluation of drugs applicable to treatment of migraine in the cranial circulation of the monkey.
    Research and clinical studies in headache, 1978, Volume: 6

    Topics: Acetylcholine; Animals; Bradykinin; Cerebrovascular Circulation; Cimetidine; Clonidine; Dose-Respons

1978
[Drug therapy for headache: (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1977, Apr-08, Volume: 119, Issue:14

    Topics: Analgesics; Anti-Inflammatory Agents; Antidepressive Agents; Clonidine; Dihydroergotamine; Ergotamin

1977
Migraine in childhood. A review.
    Clinical pediatrics, 1979, Volume: 18, Issue:6

    Topics: Acute Disease; Age Factors; Anticonvulsants; Child; Child, Preschool; Clonidine; Ergotamines; Female

1979
Migraine. Prophylactic drugs.
    Nursing mirror, 1977, Aug-11, Volume: 145, Issue:6

    Topics: Anticonvulsants; Clonidine; Cyproheptadine; Dihydroergotamine; Humans; Methysergide; Migraine Disord

1977
[Therapy of migraine and vasomotor cephalea].
    Deutsche medizinische Wochenschrift (1946), 1978, Apr-21, Volume: 103, Issue:16

    Topics: Adrenal Cortex Hormones; Analgesics; Antidepressive Agents; Barbiturates; Clonidine; Ergotamines; Hu

1978
The diagnosis and management of migraine.
    Scottish medical journal, 1978, Volume: 23, Issue:4

    Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Aspirin; Child; Clonidine; Ergotamine; Ergotamines; F

1978
Prophylaxis of migraine.
    The Medical journal of Australia, 1977, Jun-18, Volume: 1, Issue:25

    Topics: Adult; Aged; Clonidine; Female; Humans; Male; Middle Aged; Migraine Disorders

1977
Clonidine in migraine prophylaxis.
    Headache, 1977, Volume: 17, Issue:4

    Topics: Adult; Clonidine; Female; Humans; Male; Middle Aged; Migraine Disorders; Practolol

1977
Drugs for migraine.
    The Medical letter on drugs and therapeutics, 1976, Jun-18, Volume: 18, Issue:13

    Topics: Caffeine; Clonidine; Drug Synergism; Ergotamine; Heart Valve Diseases; Humans; Methysergide; Migrain

1976
[The use of drugs in migraine].
    Minerva medica, 1976, Jun-02, Volume: 67, Issue:28

    Topics: Acetaminophen; Antiemetics; Aspirin; Clonidine; Dihydroergotamine; Ergotamine; Humans; Hypnotics and

1976
[Therapeutic possibilities in idiopathic headaches. Analysis of about 1000 cases].
    Minerva medica, 1976, Jun-23, Volume: 67, Issue:31

    Topics: Cinnarizine; Clonidine; Cyproheptadine; Headache; Histamine; Humans; Methysergide; Migraine Disorder

1976
The effects of clonidine in the prophylactic treatment of migraine.
    Headache, 1975, Volume: 14, Issue:4

    Topics: Adult; Clonidine; Female; Humans; Male; Middle Aged; Migraine Disorders

1975
Letter: Clinical evaluation of clonidine in the treatment of migraine.
    The Medical journal of Australia, 1975, May-24, Volume: 1, Issue:21

    Topics: Adolescent; Adult; Aged; Clonidine; Female; Humans; Male; Middle Aged; Migraine Disorders

1975
Letter: Clonidine in the treatment of migraine.
    The Medical journal of Australia, 1975, Jul-19, Volume: 2, Issue:3

    Topics: Adult; Clonidine; Female; Humans; Male; Migraine Disorders

1975
Letter: Treatment of migraine with piracetam and clonidine.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975, Oct-04, Volume: 49, Issue:42

    Topics: Clonidine; Drug Therapy, Combination; Humans; Male; Migraine Disorders; Piracetam; Pyrrolidinones

1975
Low-dose clonidine: a review of its therapeutic efficacy in migraine prophylaxis.
    Drugs, 1975, Volume: 10, Issue:5-6

    Topics: Clonidine; Humans; Migraine Disorders; Placebos; Time Factors

1975
The metabolic and hormonal response to glucagon. Part 2. In patients with migraine.
    Journal of the neurological sciences, 1976, Volume: 27, Issue:3

    Topics: Adult; Blood Glucose; Clonidine; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Growth H

1976
Management of migraine.
    Irish medical journal, 1992, Volume: 85, Issue:1

    Topics: Adrenal Cortex Hormones; Aspirin; Clonidine; Humans; Indoles; Migraine Disorders; Propranolol; Sulfo

1992
Sumatriptan and other drugs used in migraine treatment.
    The Australian nurses' journal. Royal Australian Nursing Federation, 1992, Volume: 22, Issue:1

    Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricycl

1992
Clonidine in migraine prophylaxis--now obsolete.
    Drug and therapeutics bulletin, 1990, Oct-01, Volume: 28, Issue:20

    Topics: Clonidine; Humans; Migraine Disorders

1990
Clonidine dosage.
    American family physician, 1990, Volume: 42, Issue:5

    Topics: Clonidine; Humans; Migraine Disorders

1990
Neuroendocrine evidence of deranged noradrenergic activity in chronic migraine.
    Psychoneuroendocrinology, 1989, Volume: 14, Issue:5

    Topics: Adult; beta-Endorphin; Clonidine; Dexamethasone; Female; Headache; Humans; Hydrocortisone; Male; Mid

1989
[Antimigrainous agents used in maintenance treatment].
    La Revue du praticien, 1986, Jan-21, Volume: 36, Issue:5

    Topics: Adrenergic beta-Antagonists; Amitriptyline; Aspirin; Benzoxepins; Calcium Channel Blockers; Cinnariz

1986
Endorphin patterns within the headache spectrum disorders.
    Cephalalgia : an international journal of headache, 1985, Volume: 5 Suppl 2

    Topics: Adrenocorticotropic Hormone; Adult; beta-Endorphin; Chronic Disease; Clonidine; Cluster Headache; De

1985
Clonidine. Quo vadis?
    The Medical journal of Australia, 1985, Feb-18, Volume: 142, Issue:4

    Topics: Adrenal Gland Neoplasms; Anxiety Disorders; Climacteric; Clonidine; Female; Humans; Hypertension; Mi

1985
[Less known indications for the use of clonidine].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1985, Feb-15, Volume: 38, Issue:4

    Topics: Alcohol Amnestic Disorder; Brain Diseases; Clonidine; Glaucoma; Humans; Migraine Disorders; Opioid-R

1985
The management of migraine.
    Scottish medical journal, 1985, Volume: 30, Issue:4

    Topics: Clonidine; Diet; Dihydroergotamine; Female; Humans; Male; Methysergide; Migraine Disorders; Pizotyli

1985
Clonidine in migraine.
    Lancet (London, England), 1972, Apr-22, Volume: 1, Issue:7756

    Topics: Antihypertensive Agents; Clonidine; Humans; Imidazoles; Migraine Disorders

1972
Clonidine in migraine.
    Lancet (London, England), 1972, Jun-03, Volume: 1, Issue:7762

    Topics: Antihypertensive Agents; Clonidine; Humans; Imidazoles; Migraine Disorders; Time Factors

1972
Clonidine against migraine.
    Lancet (London, England), 1973, Sep-01, Volume: 2, Issue:7827

    Topics: Adolescent; Adult; Aged; Child; Clonidine; Female; Humans; Male; Middle Aged; Migraine Disorders; Re

1973
A comparative trial of prindolol, clonidine and carbamazepine in the interval therapy of migraine.
    The Medical journal of Australia, 1972, Jun-24, Volume: 1, Issue:26

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Animals; Anticonvulsants; Antihypertensive Age

1972
Letter: Propranolol in the treatment of migraine.
    British medical journal, 1974, Aug-24, Volume: 3, Issue:5929

    Topics: Adult; Cardiomyopathy, Hypertrophic; Clonidine; Female; Humans; Male; Middle Aged; Migraine Disorder

1974
The long-term management of migraine with clonidine.
    The Practitioner, 1972, Volume: 208, Issue:247

    Topics: Adolescent; Adult; Child; Clonidine; Female; Humans; Long-Term Care; Male; Middle Aged; Migraine Dis

1972
Atypical migraine.
    The Practitioner, 1973, Volume: 211, Issue:263

    Topics: Aneurysm; Anxiety; Blood Pressure; Clonidine; Diagnosis, Differential; Ergotamine; Headache; Humans;

1973
Dixarit--a treatment for migraine.
    Nursing times, 1973, Nov-15, Volume: 69, Issue:46

    Topics: Clonidine; Humans; Migraine Disorders

1973
[Drug information. Catapresan 25. A new migraine remedy on the market].
    Ugeskrift for laeger, 1973, Nov-12, Volume: 135, Issue:46

    Topics: Clonidine; Humans; Migraine Disorders

1973
Letter: Clonidine in treatment of dysmenorrhea.
    British medical journal, 1974, Mar-23, Volume: 1, Issue:5907

    Topics: Clonidine; Dysmenorrhea; Female; Humans; Migraine Disorders; Uterus

1974