Page last updated: 2024-10-25

clonazepam and Uremia

clonazepam has been researched along with Uremia in 5 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"In both cases the myoclonus was abolished after the intravenous administration of clonazepam."1.26Uraemic myoclonus: an example of reticular reflex myoclonus? ( Chadwick, D; French, AT, 1979)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Molnar, MZ1
Novak, M1
Mucsi, I1
Enomoto, M1
Inoue, Y1
Namba, K1
Munezawa, T1
Matsuura, M1
Read, DJ1
Feest, TG1
Nassim, MA1
Braude, W1
Barnes, T1
Chadwick, D1
French, AT1

Reviews

1 review available for clonazepam and Uremia

ArticleYear
Management of restless legs syndrome in patients on dialysis.
    Drugs, 2006, Volume: 66, Issue:5

    Topics: Amines; Anticonvulsants; Benzothiazoles; Clonazepam; Cyclohexanecarboxylic Acids; Dopamine Agents; G

2006

Other Studies

4 other studies available for clonazepam and Uremia

ArticleYear
Clinical characteristics of restless legs syndrome in end-stage renal failure and idiopathic RLS patients.
    Movement disorders : official journal of the Movement Disorder Society, 2008, Apr-30, Volume: 23, Issue:6

    Topics: Adult; Age of Onset; Aged; Anticonvulsants; Azepines; Clonazepam; Dopamine Agents; Female; Humans; K

2008
Clonazepam: effective treatment for restless legs syndrome in uraemia.
    British medical journal (Clinical research ed.), 1981, Oct-03, Volume: 283, Issue:6296

    Topics: Adolescent; Adult; Aged; Benzodiazepinones; Clonazepam; Female; Humans; Male; Middle Aged; Restless

1981
Clonazepam: effective treatment for restless legs syndrome in uraemia.
    British medical journal (Clinical research ed.), 1982, Feb-13, Volume: 284, Issue:6314

    Topics: Clonazepam; Humans; Restless Legs Syndrome; Uremia

1982
Uraemic myoclonus: an example of reticular reflex myoclonus?
    Journal of neurology, neurosurgery, and psychiatry, 1979, Volume: 42, Issue:1

    Topics: Acute Kidney Injury; Aged; Carcinoma, Transitional Cell; Clonazepam; Endocarditis, Bacterial; Humans

1979