clonazepam has been researched along with Tourette Syndrome in 12 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In orthostatic test, patients with Tourette syndrome demonstrated an unfavorable hypersympathicotonic type of cardiovascular system reaction." | 1.33 | [Autonomic cardiovascular regulation in patients with tics and Tourette syndrome]. ( Begasheva, OI; Kabanova, SA; Komarova, IB; Nazarova, EK; Zykov, VP, 2005) |
| "Patients with Tourette's syndrome often develop multiple psychopathological symptoms beyond the basic symptoms (motor and vocal tics)." | 1.31 | [Disguised Tourette's syndrome. A contribution to the differential diagnosis on phobia and fear]. ( Barnett, W; Bednarz, K; Haisch, S, 2002) |
| "A case of a 13 year-old boy with Gilles de la Tourette's syndrome is described." | 1.27 | A case of Gilles de la Tourette's syndrome treated with clonazepam. ( Kaim, B, 1983) |
| "Because patients with Tourette's syndrome have been reported to have increased red blood cell choline levels, choline levels were examined in relation to treatment response." | 1.27 | Blood choline and response to clonazepam and haloperidol in Tourette's syndrome. ( Hanin, I; Kopp, U; Merikangas, JR; Merikangas, KR, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kovacs, N | 1 |
| Herold, R | 1 |
| Janszky, J | 1 |
| Komoly, S | 1 |
| Nagy, F | 1 |
| Bednarz, K | 1 |
| Haisch, S | 1 |
| Barnett, W | 1 |
| Cersosimo, MG | 1 |
| Koller, WC | 1 |
| Zykov, VP | 1 |
| Komarova, IB | 1 |
| Nazarova, EK | 1 |
| Begasheva, OI | 1 |
| Kabanova, SA | 1 |
| Kaim, B | 1 |
| Gonce, M | 1 |
| Barbeau, A | 1 |
| Goetz, CG | 1 |
| Wong, T | 1 |
| Tiessen, E | 1 |
| Erenberg, G | 1 |
| Gillman, MA | 1 |
| Sandyk, R | 1 |
| Andermann, F | 1 |
| Andermann, E | 1 |
| Merikangas, JR | 1 |
| Merikangas, KR | 1 |
| Kopp, U | 1 |
| Hanin, I | 1 |
2 reviews available for clonazepam and Tourette Syndrome
| Article | Year |
|---|---|
Clonidine and clonazepam in Tourette syndrome.
Topics: Clonazepam; Clonidine; Humans; Tourette Syndrome | 1992 |
Excessive startle syndromes: startle disease, jumping, and startle epilepsy.
Topics: Clonazepam; Diagnosis, Differential; Echolalia; Electroencephalography; Electromyography; Epilepsy; | 1986 |
10 other studies available for clonazepam and Tourette Syndrome
| Article | Year |
|---|---|
Tics status: a movement disorder emergency: observations.
Topics: Adolescent; Antipsychotic Agents; Clonazepam; Creatine Kinase; Diagnostic and Statistical Manual of | 2011 |
[Disguised Tourette's syndrome. A contribution to the differential diagnosis on phobia and fear].
Topics: Adult; Anxiety Disorders; Clomipramine; Clonazepam; Cognitive Behavioral Therapy; Combined Modality | 2002 |
Movement disorders.
Topics: Adult; Aged; Anticonvulsants; Atrophy; Brain; Child; Clonazepam; Diagnosis, Differential; Female; Hu | 2003 |
[Autonomic cardiovascular regulation in patients with tics and Tourette syndrome].
Topics: Anti-Dyskinesia Agents; Anticonvulsants; Autonomic Nervous System Diseases; Child; Clonazepam; Femal | 2005 |
A case of Gilles de la Tourette's syndrome treated with clonazepam.
Topics: Adolescent; Benzodiazepinones; Clonazepam; Humans; Male; Tourette Syndrome | 1983 |
Seven cases of Gilles de la tourette's syndrome: partial relief with clonazepam: a pilot study.
Topics: Adolescent; Adult; Benzodiazepinones; Clonazepam; Drug Evaluation; Female; Humans; Male; Middle Aged | 1977 |
Seizure in gradual clonazepam withdrawal.
Topics: Adult; Clonazepam; Epilepsy, Tonic-Clonic; Humans; Male; Substance Withdrawal Syndrome; Tourette Syn | 1989 |
Pharmacologic therapy of tics in childhood.
Topics: Adolescent; Adult; Child; Clonazepam; Clonidine; Haloperidol; Humans; Pimozide; Tic Disorders; Toure | 1988 |
Clonazepam-induced Tourette syndrome in a subject with hyperexplexia.
Topics: Adult; Clonazepam; Female; Humans; Psychophysiologic Disorders; Reflex, Startle; Tourette Syndrome | 1987 |
Blood choline and response to clonazepam and haloperidol in Tourette's syndrome.
Topics: Adolescent; Adult; Benzodiazepinones; Child; Choline; Clonazepam; Erythrocytes; Female; Haloperidol; | 1985 |