clonazepam has been researched along with Tinnitus in 10 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Tinnitus: A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the effect of Ginkgo biloba and clonazepam, a γ-aminobutyric acid (GABA)-receptor agonist, upon tinnitus." | 9.16 | Clonazepam quiets tinnitus: a randomised crossover study with Ginkgo biloba. ( Choi, HK; Chun, W; Han, SS; Lee, KU; Levine, RA; Nam, EC; Won, JY, 2012) |
| "Present study investigates the combination of Deanxit and clonazepam (Rivotril) intake for relief of tinnitus complaints, respecting a double-blind placebo-controlled approach for Deanxit in a crossover setup." | 9.15 | Administration of the combination clonazepam-Deanxit as treatment for tinnitus. ( De Ridder, D; Meeus, O; Van de Heyning, P, 2011) |
| "We carried out a retrospective survey of 25 years of clinical experience with the use of clonazepam as a vestibular and tinnitus suppressant in the pharmacological treatment of vestibular or cochleovestibular disorders due to different causes." | 7.71 | Clonazepam in the pharmacological treatment of vertigo and tinnitus. ( Caovilla, HH; da Silva, ML; Ganança, CF; Ganança, FF; Ganança, MM; Munhoz, MS; Serafini, F, 2002) |
| "(-)-Baclofen was the only one of the three compounds tested that reversed in a dose-dependent manner the effects of tone exposure on both the amplitude of the click-evoked potentials recorded from the IC and on measures of the changes in temporal integration based on these potentials." | 5.29 | Effects of (-)-baclofen, clonazepam, and diazepam on tone exposure-induced hyperexcitability of the inferior colliculus in the rat: possible therapeutic implications for pharmacological management of tinnitus and hyperacusis. ( Møller, AR; Szczepaniak, WS, 1996) |
| "To assess the effect of Ginkgo biloba and clonazepam, a γ-aminobutyric acid (GABA)-receptor agonist, upon tinnitus." | 5.16 | Clonazepam quiets tinnitus: a randomised crossover study with Ginkgo biloba. ( Choi, HK; Chun, W; Han, SS; Lee, KU; Levine, RA; Nam, EC; Won, JY, 2012) |
| "Present study investigates the combination of Deanxit and clonazepam (Rivotril) intake for relief of tinnitus complaints, respecting a double-blind placebo-controlled approach for Deanxit in a crossover setup." | 5.15 | Administration of the combination clonazepam-Deanxit as treatment for tinnitus. ( De Ridder, D; Meeus, O; Van de Heyning, P, 2011) |
| "We carried out a retrospective survey of 25 years of clinical experience with the use of clonazepam as a vestibular and tinnitus suppressant in the pharmacological treatment of vestibular or cochleovestibular disorders due to different causes." | 3.71 | Clonazepam in the pharmacological treatment of vertigo and tinnitus. ( Caovilla, HH; da Silva, ML; Ganança, CF; Ganança, FF; Ganança, MM; Munhoz, MS; Serafini, F, 2002) |
| "(-)-Baclofen was the only one of the three compounds tested that reversed in a dose-dependent manner the effects of tone exposure on both the amplitude of the click-evoked potentials recorded from the IC and on measures of the changes in temporal integration based on these potentials." | 1.29 | Effects of (-)-baclofen, clonazepam, and diazepam on tone exposure-induced hyperexcitability of the inferior colliculus in the rat: possible therapeutic implications for pharmacological management of tinnitus and hyperacusis. ( Møller, AR; Szczepaniak, WS, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shikino, K | 1 |
| Sato, R | 1 |
| Hanazawa, N | 1 |
| Yasuda, M | 1 |
| Ikusaka, M | 1 |
| Meeus, O | 1 |
| De Ridder, D | 1 |
| Van de Heyning, P | 1 |
| Staab, JP | 1 |
| Han, SS | 1 |
| Nam, EC | 1 |
| Won, JY | 1 |
| Lee, KU | 1 |
| Chun, W | 1 |
| Choi, HK | 1 |
| Levine, RA | 1 |
| Shaikh, AG | 1 |
| Shulman, A | 1 |
| Strashun, AM | 1 |
| Goldstein, BA | 1 |
| Ganança, MM | 1 |
| Caovilla, HH | 1 |
| Ganança, FF | 1 |
| Ganança, CF | 1 |
| Munhoz, MS | 1 |
| da Silva, ML | 1 |
| Serafini, F | 1 |
| Bouccara, D | 1 |
| Dauman, R | 1 |
| Geoffray, B | 1 |
| Londero, A | 1 |
| Bonfils, P | 1 |
| Bahmad, FM | 1 |
| Venosa, AR | 1 |
| Oliveira, CA | 1 |
| Szczepaniak, WS | 1 |
| Møller, AR | 1 |
3 trials available for clonazepam and Tinnitus
| Article | Year |
|---|---|
Administration of the combination clonazepam-Deanxit as treatment for tinnitus.
Topics: Adult; Anthracenes; Clonazepam; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; | 2011 |
Clonazepam quiets tinnitus: a randomised crossover study with Ginkgo biloba.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Clonazepam; Cross-Over Studies; Female; GABA Agonists; G | 2012 |
Benzodiazepines and GABAergics in treating severe disabling tinnitus of predominantly cochlear origin.
Topics: Adult; Amines; Benzodiazepines; Clonazepam; Cochlear Diseases; Cyclohexanecarboxylic Acids; Disabili | 2006 |
7 other studies available for clonazepam and Tinnitus
| Article | Year |
|---|---|
Chronic clicking tinnitus due to palatal tremor: essential or secondary?
Topics: Anticonvulsants; Clonazepam; Female; Humans; Middle Aged; Myoclonus; Tinnitus; Tremor | 2021 |
Comment on Administration of the combination clonazepam-Deanxit as treatment for tinnitus.
Topics: Anthracenes; Clonazepam; Female; Flupenthixol; GABA Modulators; Humans; Male; Tinnitus | 2012 |
A journey of tinnitus: myths, models, membranes and medicines.
Topics: Clonazepam; Female; GABA Agonists; Ginkgo biloba; Humans; Male; Phytotherapy; Plant Extracts; Tinnit | 2012 |
GABAA-benzodiazepine-chloride receptor-targeted therapy for tinnitus control: preliminary report.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Benzodiazepines; Chloride Channels; Clonazepam; Cy | 2002 |
Clonazepam in the pharmacological treatment of vertigo and tinnitus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Clonazepam; Evaluation Studies as Topic; Female; GABA Mo | 2002 |
[Tinnitus in young adults].
Topics: Adult; Age Factors; Anti-Anxiety Agents; Audiometry; Clonazepam; Counseling; Female; Follow-Up Studi | 2006 |
Effects of (-)-baclofen, clonazepam, and diazepam on tone exposure-induced hyperexcitability of the inferior colliculus in the rat: possible therapeutic implications for pharmacological management of tinnitus and hyperacusis.
Topics: Acoustic Stimulation; Animals; Auditory Threshold; Baclofen; Clonazepam; Diazepam; Disease Models, A | 1996 |