clonazepam has been researched along with Syndrome in 43 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study direction and intensity of autonomic changes in patients with paroxysmal atrial fibrillation (PAF) treated with clonazepam and their dynamics during antiarrhythmic therapy." | 7.73 | [Effect of clonazepam and antiarrhythmic drugs on heart rate variability in patients with paroxysmal atrial fibrillation]. ( Khaspekova, NB; Nedostup, AV; San'kova, TA; Solov'ëva, AD, 2005) |
| " I report a patient who developed the syndrome during treatment for schizophrenia with the antipsychotic agent molindone hydrochloride." | 7.68 | Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen. ( Sandyk, R, 1990) |
| "A study of 21 patients has shown that clonazepam is an effective drug in preventing attacks of pain in trigeminal neuralgia and Sluder's syndrome." | 7.65 | Clonazepam in cranial neuralgias. ( Scarlato, G; Smirne, S, 1977) |
| "The drug encorat, an analogue of valproic acid (Sun, India) was given to 16 children aged from 4 month to 5 years suffering from resistant forms of early infantile epilepsy." | 5.07 | [The enkorat treatment of infantile spasms and the Lennox-Gastaut syndrome]. ( Badalian, LO; Iskander, MB; Kharlamov, DA; Medvedev, MI; Mukhin, KIu; Temin, PA; Veselov, NK, 1994) |
| "To study direction and intensity of autonomic changes in patients with paroxysmal atrial fibrillation (PAF) treated with clonazepam and their dynamics during antiarrhythmic therapy." | 3.73 | [Effect of clonazepam and antiarrhythmic drugs on heart rate variability in patients with paroxysmal atrial fibrillation]. ( Khaspekova, NB; Nedostup, AV; San'kova, TA; Solov'ëva, AD, 2005) |
| " I report a patient who developed the syndrome during treatment for schizophrenia with the antipsychotic agent molindone hydrochloride." | 3.68 | Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen. ( Sandyk, R, 1990) |
| "The therapeutics results with the use of different drugs (diazepam, nitrazepam, clonazepam, diphenylhydantoin, barbiturates--phenobarbital and primidone--, sodium dipropylacetate and ACTH) in twenty-nine patients with Lennox--Gastaut syndrome are carefully analysed." | 3.65 | [Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome]. ( Lison, MP; Speciali, GG, 1977) |
| "A study of 21 patients has shown that clonazepam is an effective drug in preventing attacks of pain in trigeminal neuralgia and Sluder's syndrome." | 3.65 | Clonazepam in cranial neuralgias. ( Scarlato, G; Smirne, S, 1977) |
| "Post-hypoxic myoclonus (PHM) is a rare neurological complication having two different variants depending on acute or chronic onset after cardiopulmonary resuscitation following cardiac arrest: myoclonic status epilepticus (MSE) and Lance-Adams syndrome (LAS) respectively." | 3.01 | Post-hypoxic myoclonus; what we know and gaps in knowledge. ( Ahmed, HS, 2023) |
| " We investigated the effect of piracetam and clonazepam, an anti-epileptic drug, on high dosage urea-induced myoclonus using an electromyogram in rats." | 2.41 | [A pharmacological profile of piracetam (Myocalm), a drug for myoclonus]. ( Nanri, M; Tajima, K, 2000) |
| "FOXG1 syndrome is a severe encephalopathy that exhibit intellectual disability, emotional disorder, and limited social communication." | 1.51 | Loss of Foxg1 Impairs the Development of Cortical SST-Interneurons Leading to Abnormal Emotional and Social Behaviors. ( Chen, D; Chen, H; Li, M; She, X; Wang, C; Yuan, Y; Zhang, W; Zhao, C, 2019) |
| "Early myoclonus after cardiac arrest (CA) is traditionally viewed as a poor prognostic sign (status myoclonus)." | 1.46 | Early Lance-Adams syndrome after cardiac arrest: Prevalence, time to return to awareness, and outcome in a large cohort. ( Aicua Rapun, I; Novy, J; Oddo, M; Rossetti, AO; Solari, D, 2017) |
| "Psychotic features in patients with Parkinson's Disease usually present as visual hallucinations against a background of cognitive deterioration and dopaminomimetic therapy." | 1.36 | Isolated delusional syndrome in Parkinson's Disease. ( Bozi, M; Christodoulou, C; Douzenis, A; Gasparinatos, G; Stamboulis, E; Stefanis, C; Stefanis, L; Stefanis, N, 2010) |
| "Epilepsy was most common among those with maternal deletions and unknown subtypes, with catastrophic epilepsies present in only these two subtypes." | 1.35 | Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options. ( Braun, EK; Bruno, P; Conant, KD; Nespeca, MP; Said, RR; Thibert, RL; Thiele, EA, 2009) |
| "Clonazepam was the most effective antiepileptic drug, and it also normalized the EEG when started in childhood or at the onset of puberty." | 1.30 | Neurophysiological findings in the northern epilepsy syndrome. ( Hirvasniemi, A; Lang, AH; Siivola, J, 1997) |
| "Orthostatic tremor is an unusual kind of potentially disabiling tremor appearing immediately when standing." | 1.30 | ["Primary" orthostatic tremor. 10 clinical electrophysiologic observations]. ( Cassim, F; Destée, A; Guieu, JD; Mastain, B, 1998) |
| "One also had features of infantile autism." | 1.29 | Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs. ( Chesler, N; Christianson, AL; Kromberg, JG, 1994) |
| "Orthostatic tremor is a disabling condition that responds to benzodiazepine treatment and may be more frequent than previously recognised." | 1.29 | Orthostatic tremor (shaky legs syndrome). ( Gates, PC, 1993) |
| "Posthypoxic myoclonus (Lance-Adams' syndrome) is a rare complication of cardiorespiratory arrest." | 1.29 | Posthypoxic myoclonus in intensive care. ( Chamorro, A; del Mar Lluch, M; Millá, J; Miró, O; Nadal, P; Urbano-Márquez, A, 1994) |
| "Posthypoxic myoclonus is a rare complication of successful cardiopulmonary resusitation." | 1.28 | Posthypoxic myoclonus (the Lance-Adams syndrome) in the intensive care unit. ( Harper, SJ; Wilkes, RG, 1991) |
| "Chronic hypoxemia, hypercarbia, bronchospasm, and inadequate nutrition were present in all." | 1.28 | Movement disorder of premature infants with severe bronchopulmonary dysplasia: a new syndrome. ( Perlman, JM; Volpe, JJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (30.23) | 18.7374 |
| 1990's | 14 (32.56) | 18.2507 |
| 2000's | 8 (18.60) | 29.6817 |
| 2010's | 7 (16.28) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmed, HS | 1 |
| Aicua Rapun, I | 1 |
| Novy, J | 1 |
| Solari, D | 1 |
| Oddo, M | 1 |
| Rossetti, AO | 1 |
| Chen, D | 1 |
| Wang, C | 1 |
| Li, M | 1 |
| She, X | 1 |
| Yuan, Y | 1 |
| Chen, H | 1 |
| Zhang, W | 1 |
| Zhao, C | 1 |
| Lagrand, T | 1 |
| Winogrodzka, A | 1 |
| Horváth, K | 1 |
| Aschermann, Z | 1 |
| Komoly, S | 1 |
| Kovács, A | 1 |
| Kovács, N | 1 |
| Thibert, RL | 1 |
| Conant, KD | 1 |
| Braun, EK | 1 |
| Bruno, P | 1 |
| Said, RR | 1 |
| Nespeca, MP | 1 |
| Thiele, EA | 1 |
| Stefanis, N | 1 |
| Bozi, M | 1 |
| Christodoulou, C | 1 |
| Douzenis, A | 1 |
| Gasparinatos, G | 1 |
| Stamboulis, E | 1 |
| Stefanis, C | 1 |
| Stefanis, L | 1 |
| Han, S | 1 |
| Tai, C | 1 |
| Westenbroek, RE | 1 |
| Yu, FH | 1 |
| Cheah, CS | 1 |
| Potter, GB | 1 |
| Rubenstein, JL | 1 |
| Scheuer, T | 1 |
| de la Iglesia, HO | 1 |
| Catterall, WA | 1 |
| Azad, C | 1 |
| Guglani, V | 1 |
| Kaga, M | 1 |
| Horimoto, R | 1 |
| Hatori, T | 1 |
| Wheless, JW | 1 |
| Kreisel, SH | 1 |
| Binder, J | 1 |
| Wöhrle, JC | 1 |
| Krauss, JK | 1 |
| Hofmann, S | 1 |
| Bauer, MF | 1 |
| Hennerici, MG | 1 |
| Bäzner, H | 1 |
| Khaspekova, NB | 1 |
| Solov'ëva, AD | 1 |
| Nedostup, AV | 1 |
| San'kova, TA | 1 |
| Raudino, F | 1 |
| Bahi-Buisson, N | 1 |
| Savini, R | 1 |
| Eisermann, M | 1 |
| Bulteau, C | 1 |
| Dulac, O | 1 |
| Hertz-Pannier, L | 1 |
| Chiron, C | 1 |
| Boldyrev, AI | 1 |
| Tibbles, JA | 1 |
| Barnes, SE | 1 |
| Christianson, AL | 1 |
| Chesler, N | 1 |
| Kromberg, JG | 1 |
| Hirvasniemi, A | 2 |
| Herrala, P | 1 |
| Leisti, J | 1 |
| Gates, PC | 1 |
| Badalian, LO | 1 |
| Temin, PA | 1 |
| Medvedev, MI | 1 |
| Mukhin, KIu | 1 |
| Iskander, MB | 1 |
| Kharlamov, DA | 1 |
| Veselov, NK | 1 |
| Garg, RK | 1 |
| Kar, AM | 1 |
| Dixit, V | 1 |
| Tan, AK | 1 |
| Tan, CB | 1 |
| Lang, AH | 1 |
| Siivola, J | 1 |
| Miró, O | 1 |
| Chamorro, A | 1 |
| del Mar Lluch, M | 1 |
| Nadal, P | 1 |
| Millá, J | 1 |
| Urbano-Márquez, A | 1 |
| Rella, JG | 1 |
| Hoffman, RS | 1 |
| Nakamura, M | 1 |
| Yamagata, T | 1 |
| Momoi, MY | 1 |
| Yamazaki, T | 1 |
| Mastain, B | 1 |
| Cassim, F | 1 |
| Guieu, JD | 1 |
| Destée, A | 1 |
| Tajima, K | 1 |
| Nanri, M | 1 |
| Nyland, H | 1 |
| Mellgren, SI | 1 |
| Frövig, AG | 1 |
| Speciali, GG | 1 |
| Lison, MP | 1 |
| Westblom, U | 2 |
| Lance, JW | 1 |
| Smirne, S | 1 |
| Scarlato, G | 1 |
| Berman, W | 1 |
| Dubowitz, LM | 1 |
| Bouza, H | 1 |
| Hird, MF | 1 |
| Jaeken, J | 1 |
| Harper, SJ | 1 |
| Wilkes, RG | 1 |
| Sandyk, R | 1 |
| Perlman, JM | 1 |
| Volpe, JJ | 1 |
| Koczerginski, D | 1 |
| Kennedy, SH | 1 |
| Swinson, RP | 1 |
| Garcia de Alba, GO | 1 |
| Malagon Valdez, J | 1 |
| Franco Delgadillo, J | 1 |
| Ramos Peek, J | 1 |
| Guilleminault, C | 1 |
| Crowe, C | 1 |
| Quera-Salva, MA | 1 |
| Miles, L | 1 |
| Partinen, M | 1 |
5 reviews available for clonazepam and Syndrome
| Article | Year |
|---|---|
Post-hypoxic myoclonus; what we know and gaps in knowledge.
Topics: Cardiopulmonary Resuscitation; Clonazepam; Humans; Hypoxia; Myoclonus; Syndrome; Valproic Acid | 2023 |
[Treatment of tardive syndromes].
Topics: Amantadine; Antipsychotic Agents; Botulinum Toxins; Central Nervous System Agents; Cholinergic Antag | 2014 |
[Progressive epilepsy with mental retardation(PEMR)].
Topics: Animals; Child; Child, Preschool; Chromosomes, Human, Pair 8; Clonazepam; Diagnosis, Differential; D | 2002 |
Acute management of seizures in the syndromes of idiopathic generalized epilepsies.
Topics: Acute Disease; Adolescent; Adult; Anticonvulsants; Clonazepam; Comorbidity; Drug Administration Sche | 2003 |
[A pharmacological profile of piracetam (Myocalm), a drug for myoclonus].
Topics: Animals; Anticonvulsants; Clinical Trials, Phase II as Topic; Clonazepam; Disease Models, Animal; Dr | 2000 |
1 trial available for clonazepam and Syndrome
| Article | Year |
|---|---|
[The enkorat treatment of infantile spasms and the Lennox-Gastaut syndrome].
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsy; E | 1994 |
37 other studies available for clonazepam and Syndrome
| Article | Year |
|---|---|
Early Lance-Adams syndrome after cardiac arrest: Prevalence, time to return to awareness, and outcome in a large cohort.
Topics: Adult; Aged, 80 and over; Anticonvulsants; Cardiopulmonary Resuscitation; Clonazepam; Drug Combinati | 2017 |
Loss of Foxg1 Impairs the Development of Cortical SST-Interneurons Leading to Abnormal Emotional and Social Behaviors.
Topics: Animals; Behavior, Animal; Brain Diseases; Cerebral Cortex; Clonazepam; Cognition; Depression; Emoti | 2019 |
Late relapse myoclonus in a case of Lance-Adams syndrome.
Topics: Aged; Clonazepam; Humans; Hypoxia, Brain; Male; Myoclonus; Recurrence; Syndrome | 2013 |
Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options.
Topics: Adolescent; Adult; Angelman Syndrome; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbid | 2009 |
Isolated delusional syndrome in Parkinson's Disease.
Topics: Aged; Amantadine; Antiparkinson Agents; Benserazide; Benzothiazoles; Catechols; Clonazepam; Female; | 2010 |
Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission.
Topics: Animals; Anxiety; Autistic Disorder; Clonazepam; Epilepsies, Myoclonic; GABA Modulators; GABAergic N | 2012 |
Eyelid myoclonia with absence seizure precipitated by carbamazepine therapy.
Topics: Carbamazepine; Child; Clonazepam; Epilepsy, Absence; Female; Humans; Myoclonus; Syndrome; Valproic A | 2012 |
Dystonia in the Mohr-Tranebjaerg syndrome responds to GABAergic substances.
Topics: Adult; Clonazepam; Cognition Disorders; Dystonic Disorders; GABA Modulators; Genetic Diseases, X-Lin | 2004 |
[Effect of clonazepam and antiarrhythmic drugs on heart rate variability in patients with paroxysmal atrial fibrillation].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Anticonvulsants; Atrial Fibrillation; Autonomic Nervous System; | 2005 |
SUNCT: a new case with some unusual features.
Topics: Adult; Clonazepam; Conjunctival Diseases; GABA Modulators; Headache; Humans; Magnetic Resonance Imag | 2005 |
Misleading effects of clonazepam in symptomatic electrical status epilepticus during sleep syndrome.
Topics: Anticonvulsants; Child; Clonazepam; Cognition Disorders; Electroencephalography; Humans; Male; Motor | 2006 |
[Clinical evaluation of certain modern antiepileptic preparations].
Topics: Anticonvulsants; Automatism; Carbamazepine; Child; Clonazepam; Diencephalon; Epilepsy; Epilepsy, Abs | 1982 |
Paroxysmal dystonic choreoathetosis of Mount and Reback.
Topics: Adult; Aged; Athetosis; Child, Preschool; Chorea; Clonazepam; Female; Genes, Dominant; Humans; Male; | 1980 |
Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs.
Topics: Adult; Autistic Disorder; Child, Preschool; Clonazepam; Developmental Disabilities; Epilepsy; Family | 1994 |
Northern epilepsy syndrome: clinical course and the effect of medication on seizures.
Topics: Adolescent; Adult; Age Factors; Age of Onset; Anticonvulsants; Central Nervous System Diseases; Chil | 1995 |
Orthostatic tremor (shaky legs syndrome).
Topics: Aged; Aged, 80 and over; Arm; Chlordiazepoxide; Clonazepam; Female; Humans; Leg; Male; Middle Aged; | 1993 |
Opsoclonus--myoclonus syndrome in an adult: a case report and response to clonazepam.
Topics: Adult; Anticonvulsants; Clonazepam; Follow-Up Studies; Humans; Male; Myoclonus; Ocular Motility Diso | 1996 |
The syndrome of painful legs and moving toes--a case report.
Topics: Baclofen; Clonazepam; Female; GABA Agonists; GABA Modulators; Humans; Middle Aged; Neuromuscular Dis | 1996 |
Neurophysiological findings in the northern epilepsy syndrome.
Topics: Adolescent; Adult; Age Factors; Age of Onset; Anticonvulsants; Brain; Child; Child, Preschool; Clona | 1997 |
Posthypoxic myoclonus in intensive care.
Topics: Aged; Anticonvulsants; Cardiopulmonary Resuscitation; Clonazepam; Critical Care; Female; Follow-Up S | 1994 |
Possible serotonin syndrome from paroxetine and clonazepam.
Topics: Adult; Clonazepam; Contraindications; Drug Interactions; Female; GABA Modulators; Humans; Nervous Sy | 1998 |
Drop episodes in Coffin-Lowry syndrome: exaggerated startle responses treated with clonazepam.
Topics: Abnormalities, Multiple; Adult; Anticonvulsants; Clonazepam; Electroencephalography; Electromyograph | 1998 |
["Primary" orthostatic tremor. 10 clinical electrophysiologic observations].
Topics: Adult; Aged; Anti-Anxiety Agents; Arm; Clonazepam; Diazepam; Electromyography; Female; Humans; Leg; | 1998 |
Stiff-man syndrome with central and peripheral nervous manifestations.
Topics: Clonazepam; Diazepam; Electromyography; Humans; Male; Middle Aged; Muscle Rigidity; Muscles; NADH, N | 1978 |
[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Clonazepam; Dia | 1977 |
Stiff-man syndrome and clonazepam.
Topics: Benzodiazepinones; Clonazepam; Diazepam; Female; Humans; Middle Aged; Muscle Rigidity; Spasm; Syndro | 1977 |
Familial paroxysmal dystonic choreoathetosis of Mount and Reback and its differentiation from related syndromes.
Topics: Adolescent; Adult; Athetosis; Barbiturates; Child; Child, Preschool; Chorea; Clonazepam; Female; Hum | 1977 |
[Stiff--man syndrome].
Topics: Clonazepam; Diagnosis, Differential; Diazepam; Female; Humans; Middle Aged; Muscle Rigidity; Syndrom | 1978 |
Clonazepam in cranial neuralgias.
Topics: Adult; Aged; Benzodiazepinones; Clonazepam; Cranial Nerves; Facial Neuralgia; Female; Humans; Male; | 1977 |
Letter: The ketogenic diet, West and Lennox syndromes.
Topics: Child; Child, Preschool; Clonazepam; Diazepam; Humans; Infant; Intellectual Disability; Myoclonus; N | 1975 |
Low cerebrospinal fluid concentration of free gamma-aminobutyric acid in startle disease.
Topics: Clonazepam; Electroencephalography; Female; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Phenob | 1992 |
Posthypoxic myoclonus (the Lance-Adams syndrome) in the intensive care unit.
Topics: Clonazepam; Critical Care; Diagnosis, Differential; Humans; Hypoxia; Male; Middle Aged; Myoclonus; R | 1991 |
Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen.
Topics: Baclofen; Causalgia; Clonazepam; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Humans; | 1990 |
Movement disorder of premature infants with severe bronchopulmonary dysplasia: a new syndrome.
Topics: Bronchopulmonary Dysplasia; Clonazepam; Follow-Up Studies; Humans; Hypoxia; Infant, Newborn; Movemen | 1989 |
Clonazepam and lithium--a toxic combination in the treatment of mania?
Topics: Adult; Bipolar Disorder; Clonazepam; Female; Humans; Lithium; Male; Middle Aged; Nervous System; Syn | 1989 |
Status epilepticus within the Lennox-Gastaut syndrome: clinical characteristics and management.
Topics: Child; Clonazepam; Electroencephalography; Epilepsy; Humans; Male; Status Epilepticus; Syndrome; Val | 1987 |
Periodic leg movement, sleep fragmentation and central sleep apnoea in two cases: reduction with Clonazepam.
Topics: Adult; Clonazepam; Female; Humans; Leg; Male; Middle Aged; Myoclonus; Sleep Apnea Syndromes; Sleep W | 1988 |