Page last updated: 2024-10-25

clonazepam and Spasm

clonazepam has been researched along with Spasm in 16 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"25 patients with multiple sclerosis (MS) and other spastic disorders, 33 MS patients and 10 control patients with MS were given clonazepam, baclofen or placebo over a period of 5 days to 20 weeks."5.04Clonazepam, baclofen and placebo in the treatment of spasticity. ( Cendrowski, W; Sobczyk, W, 1977)
"To review the result of the infantile spasms' treatment with sodium valproate followed by nitrazepam or clonazepam."3.74Treatment of infantile spasms with sodium valproate followed by benzodiazepines. ( Auvichayapat, N; Auvichayapat, P; Tassniyom, S; Treerotphon, S, 2007)
" Treatment with clonazepam and propylthiouracil resulted in resolution of the myoclonic jerks within the next 3 weeks."3.73Graves' disease associated with spasmodic truncal flexion. ( Hum, AY; Lim, EC; Loh, LM; Teoh, HL, 2005)
"Masticatory spasm is a rare clinical feature and mostly associated with disorders of general movement."2.38[A case of unilateral masticatory spasm without hemifacial atrophy]. ( Aiba, T; Seki, Y; Yoshii, K, 1989)
"Herein, we present a 13-year-old generalized epilepsy patient with eating-induced generalized seizures since the age of 5."1.62Eight years follow-up of a generalized epilepsy patient with eating-induced late-onset epileptic spasms and atypical absence with myoclonic jerks. ( Chen, B; Jin, L; Liu, Y; Wang, X; Zhang, W, 2021)
"Clonic torticollis were less frequently associated to pain."1.28[Craniocervical dystonia and facial hemispasm: clinical and pharmacological characteristics of 52 patients]. ( Astarloa, R; de Yébenes, JG; Morales, B; Peñafiel, N; Rábano, J, 1991)
"Orthostatic tremor is characterized by tremor of the trunk and legs while standing."1.28Orthostatic tremor: an association with essential tremor. ( FitzGerald, PM; Jankovic, J, 1991)
"Spasms are increased by Chlorimipramine which may by used as a provocative test in uncertain cases."1.26[The stiff-man syndrome. A case report with regard to clinical, electromyographical and pharmacological signs (author's transl)]. ( Heckl, R; Stöhr, M, 1977)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's2 (12.50)18.2507
2000's3 (18.75)29.6817
2010's0 (0.00)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Shen, D1
Zhou, H1
Chen, S1
Wang, X1
Chen, B1
Jin, L1
Zhang, W1
Liu, Y1
Loh, LM1
Hum, AY1
Teoh, HL1
Lim, EC1
Auvichayapat, N1
Tassniyom, S1
Treerotphon, S1
Auvichayapat, P1
Visudhiphan, P1
Ortiz, A1
Cendrowski, W1
Sobczyk, W1
Westblom, U1
Hussey, HH1
Stöhr, M1
Heckl, R1
Berman, W1
Astarloa, R1
Morales, B1
Peñafiel, N1
Rábano, J1
de Yébenes, JG1
FitzGerald, PM1
Jankovic, J1
Yoshii, K1
Seki, Y1
Aiba, T1
Wieland, C1
Herzberg, L1

Reviews

1 review available for clonazepam and Spasm

ArticleYear
[A case of unilateral masticatory spasm without hemifacial atrophy].
    No to shinkei = Brain and nerve, 1989, Volume: 41, Issue:4

    Topics: Adult; Clonazepam; Electromyography; Facial Hemiatrophy; Humans; Hypertrophy; Male; Masseter Muscle;

1989

Trials

1 trial available for clonazepam and Spasm

ArticleYear
Clonazepam, baclofen and placebo in the treatment of spasticity.
    European neurology, 1977, Volume: 16, Issue:1-6

    Topics: Adolescent; Adult; Aged; Aminobutyrates; Baclofen; Benzodiazepinones; Clinical Trials as Topic; Clon

1977

Other Studies

14 other studies available for clonazepam and Spasm

ArticleYear
Spasms and Myoclonus in a Young Woman With Hashimoto Thyroiditis.
    JAMA neurology, 2020, 05-01, Volume: 77, Issue:5

    Topics: Adult; Anticonvulsants; Clonazepam; Diazepam; Encephalomyelitis; Female; Hashimoto Disease; Humans;

2020
Eight years follow-up of a generalized epilepsy patient with eating-induced late-onset epileptic spasms and atypical absence with myoclonic jerks.
    Brain & development, 2021, Volume: 43, Issue:1

    Topics: Adolescent; China; Clonazepam; Eating; Epilepsy, Generalized; Follow-Up Studies; Humans; Male; Myocl

2021
Graves' disease associated with spasmodic truncal flexion.
    Parkinsonism & related disorders, 2005, Volume: 11, Issue:2

    Topics: Adult; Anticonvulsants; Antithyroid Agents; Clonazepam; Graves Disease; Humans; Male; Myoclonus; Pro

2005
Treatment of infantile spasms with sodium valproate followed by benzodiazepines.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2007, Volume: 90, Issue:9

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Clonazepam; Drug Therapy, Combination

2007
Treatment of infantile spasms with sodium valproate followed by benzodiazepines.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2007, Volume: 90, Issue:10

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Clonazepam; Drug Therapy, Combination

2007
Neuropharmacological profile of Meige's disease: overview and a case report.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:4

    Topics: Aged; Baclofen; Benztropine; Clonazepam; Doxepin; Drug Therapy, Combination; Dystonia; Facial Muscle

1983
Stiff-man syndrome and clonazepam.
    JAMA, 1977, May-02, Volume: 237, Issue:18

    Topics: Benzodiazepinones; Clonazepam; Diazepam; Female; Humans; Middle Aged; Muscle Rigidity; Spasm; Syndro

1977
Editorial: Clonazepam: a new anticonvulsant.
    JAMA, 1976, Apr-05, Volume: 235, Issue:14

    Topics: Anticonvulsants; Benzodiazepinones; Clonazepam; Epilepsy, Absence; Humans; Legislation, Drug; Spasm;

1976
[The stiff-man syndrome. A case report with regard to clinical, electromyographical and pharmacological signs (author's transl)].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1977, Feb-23, Volume: 223, Issue:2

    Topics: Aged; Baclofen; Clomipramine; Clonazepam; Female; Humans; Muscle Rigidity; Muscles; Reaction Time; S

1977
Letter: The ketogenic diet, West and Lennox syndromes.
    Developmental medicine and child neurology, 1975, Volume: 17, Issue:2

    Topics: Child; Child, Preschool; Clonazepam; Diazepam; Humans; Infant; Intellectual Disability; Myoclonus; N

1975
[Craniocervical dystonia and facial hemispasm: clinical and pharmacological characteristics of 52 patients].
    Revista clinica espanola, 1991, Volume: 189, Issue:7

    Topics: Adolescent; Adult; Aged; Blepharospasm; Clonazepam; Facial Nerve Diseases; Female; Humans; Male; Mid

1991
Orthostatic tremor: an association with essential tremor.
    Movement disorders : official journal of the Movement Disorder Society, 1991, Volume: 6, Issue:1

    Topics: Aged; Clonazepam; Drug Therapy, Combination; Electromyography; Humans; Male; Middle Aged; Muscles; P

1991
Facial muscle spasms and clonazepam.
    The Medical journal of Australia, 1985, Sep-02, Volume: 143, Issue:5

    Topics: Adult; Benzodiazepinones; Clonazepam; Facial Muscles; Female; Humans; Spasm

1985
Management of hemifacial spasm with clonazepam.
    Neurology, 1985, Volume: 35, Issue:11

    Topics: Aged; Benzodiazepinones; Clonazepam; Facial Muscles; Female; Humans; Male; Middle Aged; Spasm

1985