Page last updated: 2024-10-25

clonazepam and Sleep Wake Disorders

clonazepam has been researched along with Sleep Wake Disorders in 49 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.

Research Excerpts

ExcerptRelevanceReference
"At the therapeutic endpoint, clonazepam (N = 222) proved clinically and statistically superior to placebo (N = 216) in change in the number of panic attacks and in Clinical Global Impressions-Severity of Illness (CGI-S) and CGI-Change scores, Patient's Global Impression of Change scores, amount of fear and avoidance associated with phobic symptoms, and duration of anticipatory anxiety."9.09Efficacy, safety, and gradual discontinuation of clonazepam in panic disorder: a placebo-controlled, multicenter study using optimized dosages. ( Moroz, G; Rosenbaum, JF, 1999)
"Low-dose cotherapy of fluoxetine with clonazepam was safe and accelerated response over 21 days of treatment, decreasing anxiety and sleep disturbance as symptoms and partially suppressed them as SSRI side-effects; it also modestly reduced core symptoms of low mood and loss of interest."9.09Short-term cotherapy with clonazepam and fluoxetine: anxiety, sleep disturbance and core symptoms of depression. ( Glaudin, V; Londborg, PD; Painter, JR; Smith, WT, 2000)
"Sixty patients (age-range one month to 14 years) with other types of epilepsy than infantile spasms were treated with clonazepam."7.67Clonazepam monotherapy for epilepsy in childhood. ( Ishikawa, A; Kajii, N; Kohsaka, S; Nagashima, T; Sakuma, N, 1985)
"At the therapeutic endpoint, clonazepam (N = 222) proved clinically and statistically superior to placebo (N = 216) in change in the number of panic attacks and in Clinical Global Impressions-Severity of Illness (CGI-S) and CGI-Change scores, Patient's Global Impression of Change scores, amount of fear and avoidance associated with phobic symptoms, and duration of anticipatory anxiety."5.09Efficacy, safety, and gradual discontinuation of clonazepam in panic disorder: a placebo-controlled, multicenter study using optimized dosages. ( Moroz, G; Rosenbaum, JF, 1999)
"Low-dose cotherapy of fluoxetine with clonazepam was safe and accelerated response over 21 days of treatment, decreasing anxiety and sleep disturbance as symptoms and partially suppressed them as SSRI side-effects; it also modestly reduced core symptoms of low mood and loss of interest."5.09Short-term cotherapy with clonazepam and fluoxetine: anxiety, sleep disturbance and core symptoms of depression. ( Glaudin, V; Londborg, PD; Painter, JR; Smith, WT, 2000)
"Sixty patients (age-range one month to 14 years) with other types of epilepsy than infantile spasms were treated with clonazepam."3.67Clonazepam monotherapy for epilepsy in childhood. ( Ishikawa, A; Kajii, N; Kohsaka, S; Nagashima, T; Sakuma, N, 1985)
"Trazodone intake was associated with a higher decrease in ESS score compared to clonazepam (P = 0."3.11Safety and efficacy of melatonin, clonazepam, and trazodone in patients with Parkinson's disease and sleep disorders: a randomized, double-blind trial. ( Agah, E; Aghamollaii, V; Hadi, F; Mirsepassi, Z; Mousavi, SV; Tafakhori, A; Talachi, N; Tavanbakhsh, S, 2022)
"We studied 38 patients with Parkinson's disease (PD) without dementia (mean age, 67."2.77[Sleep disorders in Parkinson's disease without dementia: a comparative randomized controlled study of melatonin and clonazepam]. ( Krasakov, IV; Litvinenko, IV; Tikhomirova, OV, 2012)
"Clonazepam was more effective than zolpidem in the improvement of sleep quality of hemodialysis patients, while zolpidem was better tolerated in these patients."2.76Comparing effects of clonazepam and zolpidem on sleep quality of patients on maintenance hemodialysis. ( Ahmadi, F; Alimadadi, A; Chamani, N; Dalili, S; Dashti-Khavidaki, S; Ghaeli, P; Hajhossein Talasaz, A; Khalili, H; Lessan-Pezeshki, M, 2011)
"Clonazepam therapy was largely ineffective in improving sleep disturbances, particularly nightmares, associated with combat-related PTSD."2.71Clonazepam for treatment of sleep disturbances associated with combat-related posttraumatic stress disorder. ( Bishop, MH; Cates, ME; Davis, LL; Lowe, JS; Woolley, TW, 2004)
"Long-term, nightly benzodiazepine treatment of injurious parasomnias and other disorders of disrupted nocturnal sleep resulted in sustained efficacy in most cases, with low risk of dosage tolerance, adverse effects, or abuse."2.68Long-term, nightly benzodiazepine treatment of injurious parasomnias and other disorders of disrupted nocturnal sleep in 170 adults. ( Mahowald, MW; Schenck, CH, 1996)
"Treatment with clonazepam was studied in a group of 20 patients suffering from periodic movements in sleep, in a double-blind parallel group design."2.66Double-blind evaluation of clonazepam on periodic leg movements in sleep. ( Lavie, P; Peled, R, 1987)
"Ekbom's syndrome, or 'restless legs syndrome' (RLS), not only causes symptoms in the extremities during waking hours, but also sleep disturbance and daytime fatigue."2.40[Restless legs. A much neglected syndrome]. ( Jönsson, R; Lindberg, E; Mallon, L; Nyström, B; Ulfberg, J, 1999)
"Patients with restless legs syndrome often have difficulty describing their symptoms."2.37Restless legs syndrome. ( Fox, GN, 1986)
"Clonazepam therapy was substantially effective in 1 case but not effective in 2 cases."1.38Atypical headbanging presentation of idiopathic sleep related rhythmic movement disorder: three cases with video-polysomnographic documentation. ( Schenck, CH; Yeh, SB, 2012)
"Clonazepam was stopped."1.36Late-onset nocturnal intractable seizure during sleep: what is the origin? ( Liesiene, V; Miliauskas, S; Sakalauskas, R; Zemaitis, M, 2010)
"The treatment with valproic acid (VPA) and clonazepam (CZP), has been very effective."1.30[Atypical benign partial epilepsy of childhood. Clinical follow-up EEG study of 3 patients]. ( Bauzano-Poley, E; Delgado-Marqués, MP; Mora-Ramírez, MD; Rodríguez-Barrionuevo, AC; Tosina-García, E, 1998)
"Clonazepam was used in both, with good clinical response."1.30[Behavior disorder of the REM sleep in 2 documented cases with polysomnography]. ( Aranda, L; Godoy, J; Lawson, B; Mesa, T; Santin, J, 1999)
"A patient with a 30-year history of somnambulism and night terrors is described."1.29Successful treatment of night terrors and somnambulism with paroxetine. ( Lillywhite, AR; Nutt, DJ; Wilson, SJ, 1994)
"Treatment with clonazepam has abolished the nocturnal behavioural disturbance."1.29Conversion disorder revisited: severe parasomnia discovered. ( Bokey, K, 1993)
"However, a number of presumed Parkinson's disease patients may eventually be diagnosed with multiple system atrophy (striatonigral degeneration subtype)."1.29Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behaviour disorder. ( Bundlie, SR; Mahowald, MW; Schenck, CH, 1996)
"In both groups, the frequency of nocturnal wandering increased with an increase in daytime stressors."1.29Forensic sleep medicine: nocturnal wandering and violence. ( Guilleminault, C; Leger, D; Moscovitch, A, 1995)
"A case of childhood-onset somnambulism is reported in which a 43-year-old man presented with repeated sleep-related injuries incurred during violent nocturnal activity, which included frenzied running, throwing punches and wielding knives."1.29A polysomnographically documented case of adult somnambulism with long-distance automobile driving and frequent nocturnal violence: parasomnia with continuing danger as a noninsane automatism? ( Mahowald, MW; Schenck, CH, 1995)
"This syndrome has been called fibrositis or fibromyalgia."1.28Polysomnography in idiopathic muscle pain syndrome (fibrositis). ( Bertorini, TE; Lemmi, H; Silva, AB, 1991)
"In 100 consecutive adults who came to a sleep disorders center complaining of repeated nocturnal injury, polysomnographic study identified five disorders: night terrors/sleepwalking (N = 54), REM sleep behavior disorder (N = 36), dissociative disorders (N = 7), nocturnal seizures (N = 2), and sleep apnea (N = 1)."1.28A polysomnographic and clinical report on sleep-related injury in 100 adult patients. ( Bundlie, SR; Hurwitz, TD; Mahowald, MW; Milner, DM; Schenck, CH, 1989)
"Those with insomnia, however, had a shorter intermovement interval than those with hypersomnia, with more leg movements in each activity epoch."1.27Periodic leg movements in sleep: effect of clonazepam treatment. ( Lavie, P; Ohanna, N; Peled, R; Rubin, AH; Zomer, J, 1985)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199013 (26.53)18.7374
1990's21 (42.86)18.2507
2000's5 (10.20)29.6817
2010's8 (16.33)24.3611
2020's2 (4.08)2.80

Authors

AuthorsStudies
Hadi, F1
Agah, E1
Tavanbakhsh, S1
Mirsepassi, Z1
Mousavi, SV1
Talachi, N1
Tafakhori, A1
Aghamollaii, V1
Gilat, M1
Marshall, NS1
Testelmans, D1
Buyse, B1
Lewis, SJG1
Reddy, MSS1
Achary, U1
Harbishettar, V1
Sivakumar, PT1
Varghese, M1
Mowla, A1
Ahmadzadeh, L1
Razeghian Jahromi, L1
Dastgheib, SA1
Attarian, H1
Applebee, G1
Yun, CH1
Ji, KH1
Miliauskas, S1
Liesiene, V1
Zemaitis, M1
Sakalauskas, R1
Bonakis, A1
Kritikou, I1
Vagiakis, E1
Nanas, S1
Papageorgiou, SG1
Dashti-Khavidaki, S1
Chamani, N1
Khalili, H1
Hajhossein Talasaz, A1
Ahmadi, F1
Lessan-Pezeshki, M1
Ghaeli, P1
Dalili, S1
Alimadadi, A1
Yeh, SB1
Schenck, CH9
Litvinenko, IV1
Krasakov, IV1
Tikhomirova, OV1
Cates, ME1
Bishop, MH1
Davis, LL1
Lowe, JS1
Woolley, TW1
Bahi-Buisson, N1
Savini, R1
Eisermann, M1
Bulteau, C1
Dulac, O1
Hertz-Pannier, L1
Chiron, C1
Peled, R5
Ohana, N1
Sharf, B1
Lavie, P5
Mahowald, MW8
Lillywhite, AR1
Wilson, SJ1
Nutt, DJ1
Chung, KF1
Wong, MT1
Bokey, K1
Bundlie, SR3
Guilleminault, C2
Moscovitch, A1
Leger, D1
Nofzinger, EA1
Reynolds, CF1
Morfis, L1
Schwartz, RS1
Cistulli, PA1
Nozawa, T1
Rodríguez-Barrionuevo, AC1
Bauzano-Poley, E1
Delgado-Marqués, MP1
Mora-Ramírez, MD1
Tosina-García, E1
Ulfberg, J1
Jönsson, R1
Lindberg, E1
Nyström, B1
Mallon, L1
Lawson, B1
Santin, J1
Aranda, L1
Godoy, J1
Mesa, T1
Moroz, G1
Rosenbaum, JF1
Londborg, PD1
Smith, WT1
Glaudin, V1
Painter, JR1
Herman, CR1
Schiffman, EL1
Look, JO1
Rindal, DB1
Shakir, RA1
Nanda, RN1
Lambie, DG1
Johnson, RH1
Montplaisir, J1
Lapierre, O1
Warnes, H1
Pelletier, G1
Silva, AB1
Bertorini, TE1
Lemmi, H1
Uchiyama, M1
Tanaka, K1
Isse, K1
Komazaki, H1
Kurata, T1
Kamaki, M1
Hirasawa, H1
Kuroda, Y1
Uchida, S1
Atsumi, Y1
Milner, DM1
Hurwitz, TD1
Culebras, A1
Moore, JT1
Crowe, C1
Quera-Salva, MA1
Miles, L1
Partinen, M1
Fox, GN1
Patterson, AL1
Ishikawa, A1
Sakuma, N1
Nagashima, T1
Kohsaka, S1
Kajii, N1
Wollman, M1
Jacobsen, JH1
Rosenberg, RS1
Huttenlocher, PR1
Spire, JP1
Ohanna, N1
Rubin, AH1
Zomer, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of alpha1- Adrenergic Receptor Antagonist Therapy on Cardiac and Striatal Transporter Uptake in Pre-Motor and Symptomatic Parkinson's Disease: A Follow up Study[NCT05109364]Phase 215 participants (Anticipated)Interventional2022-09-23Recruiting
Efficacy and Tolerability of Ramelteon in Patients With REM Behavior Disorder and Parkinsonism: A Placebo Controlled, Double Blind, Randomized, Prospective Pilot Study[NCT00745030]3 participants (Actual)Interventional2008-06-30Terminated (stopped due to Low subject recruitment and enrollment.)
Preliminary Findings of the Efficacy of Botulinum Toxin in Temporomandibular Disorders: A Randomized Clinical Trial[NCT05651256]Phase 2/Phase 320 participants (Actual)Interventional2021-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for clonazepam and Sleep Wake Disorders

ArticleYear
A critical review of the pharmacological treatment of REM sleep behavior disorder in adults: time for more and larger randomized placebo-controlled trials.
    Journal of neurology, 2022, Volume: 269, Issue:1

    Topics: Aged; Clonazepam; Double-Blind Method; Humans; Melatonin; Randomized Controlled Trials as Topic; REM

2022
REM sleep parasomnias.
    Neurologic clinics, 1996, Volume: 14, Issue:4

    Topics: Animals; Clonazepam; Dreams; Humans; Male; Penile Erection; Polysomnography; Sleep Wake Disorders; S

1996
[Periodic limb movement disorder].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:2

    Topics: Anticonvulsants; Clonazepam; Diagnosis, Differential; Dopamine Agents; Humans; Levodopa; Movement Di

1998
[Restless legs. A much neglected syndrome].
    Lakartidningen, 1999, Mar-10, Volume: 96, Issue:10

    Topics: Adolescent; Adult; Anticonvulsants; Clonazepam; Dopamine Agents; Humans; Levodopa; Polysomnography;

1999
The treatment of the restless leg syndrome with or without periodic leg movements in sleep.
    Sleep, 1992, Volume: 15, Issue:5

    Topics: Anti-Anxiety Agents; Clonazepam; Dextropropoxyphene; Dopamine Agents; Humans; Levodopa; Narcotics; P

1992
Restless legs syndrome.
    American family physician, 1986, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clonazepam; Cryotherapy; Diagnosis, Differential; Fem

1986

Trials

10 trials available for clonazepam and Sleep Wake Disorders

ArticleYear
Safety and efficacy of melatonin, clonazepam, and trazodone in patients with Parkinson's disease and sleep disorders: a randomized, double-blind trial.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022, Volume: 43, Issue:10

    Topics: Clonazepam; Double-Blind Method; Humans; Iran; Melatonin; Parkinson Disease; Sleep Wake Disorders; T

2022
Comparing Gabapentin with Clonazepam for Residual Sleeping Problems following Antidepressant Therapy in Patients with Major Depressive Disorder: A Randomized Clinical Trial.
    Clinical drug investigation, 2015, Volume: 35, Issue:8

    Topics: Adult; Amines; Antidepressive Agents; Clonazepam; Cyclohexanecarboxylic Acids; Depressive Disorder,

2015
Comparing effects of clonazepam and zolpidem on sleep quality of patients on maintenance hemodialysis.
    Iranian journal of kidney diseases, 2011, Volume: 5, Issue:6

    Topics: Adult; Aged; Clonazepam; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method;

2011
[Sleep disorders in Parkinson's disease without dementia: a comparative randomized controlled study of melatonin and clonazepam].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2012, Volume: 112, Issue:12

    Topics: Aged; Antioxidants; Clonazepam; Drug Therapy, Combination; Female; Humans; Male; Melatonin; Middle A

2012
Clonazepam for treatment of sleep disturbances associated with combat-related posttraumatic stress disorder.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:9

    Topics: Adult; Aged; Clonazepam; Combat Disorders; Cross-Over Studies; Dreams; Humans; Hypnotics and Sedativ

2004
Long-term, nightly benzodiazepine treatment of injurious parasomnias and other disorders of disrupted nocturnal sleep in 170 adults.
    The American journal of medicine, 1996, Volume: 100, Issue:3

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Chronic Disease; Clonazepam; Drug Administration Schedule; F

1996
Efficacy, safety, and gradual discontinuation of clonazepam in panic disorder: a placebo-controlled, multicenter study using optimized dosages.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:9

    Topics: Adolescent; Adult; Aged; Agoraphobia; Ambulatory Care; Clonazepam; Comorbidity; Double-Blind Method;

1999
Short-term cotherapy with clonazepam and fluoxetine: anxiety, sleep disturbance and core symptoms of depression.
    Journal of affective disorders, 2000, Volume: 61, Issue:1-2

    Topics: Adult; Aged; Anxiety; Clonazepam; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug

2000
The effectiveness of adding pharmacologic treatment with clonazepam or cyclobenzaprine to patient education and self-care for the treatment of jaw pain upon awakening: a randomized clinical trial.
    Journal of orofacial pain, 2002,Winter, Volume: 16, Issue:1

    Topics: Adult; Amitriptyline; Clonazepam; Female; GABA Modulators; Health Education, Dental; Humans; Male; M

2002
Double-blind evaluation of clonazepam on periodic leg movements in sleep.
    Journal of neurology, neurosurgery, and psychiatry, 1987, Volume: 50, Issue:12

    Topics: Clonazepam; Double-Blind Method; Drug Evaluation; Humans; Leg; Movement; Restless Legs Syndrome; Sle

1987

Other Studies

33 other studies available for clonazepam and Sleep Wake Disorders

ArticleYear
Paradoxical reaction to benzodiazepines in elderly - Case series.
    Asian journal of psychiatry, 2018, Volume: 35

    Topics: Aged; Aggression; Benzodiazepines; Clonazepam; GABA Modulators; Humans; Lorazepam; Male; Psychomotor

2018
REM dependent periodic stereotypical movements.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Oct-30, Volume: 24, Issue:14

    Topics: Brain; Clonazepam; GABA Modulators; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Movement;

2009
Zolpidem-induced sleep-related eating disorder.
    Journal of the neurological sciences, 2010, Jan-15, Volume: 288, Issue:1-2

    Topics: Benzothiazoles; Clonazepam; Dopamine Agonists; Feeding and Eating Disorders; Humans; Hypnotics and S

2010
Late-onset nocturnal intractable seizure during sleep: what is the origin?
    Medicina (Kaunas, Lithuania), 2010, Volume: 46, Issue:2

    Topics: Anticonvulsants; Clonazepam; Epilepsy; Follow-Up Studies; Humans; Male; Middle Aged; Polysomnography

2010
A familial case of sleep rhythmic movement disorder persistent into adulthood; approach to pathophysiology.
    Movement disorders : official journal of the Movement Disorder Society, 2011, Aug-01, Volume: 26, Issue:9

    Topics: Anticonvulsants; Clonazepam; Disease Progression; Electroencephalography; Humans; Male; Movement Dis

2011
Atypical headbanging presentation of idiopathic sleep related rhythmic movement disorder: three cases with video-polysomnographic documentation.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2012, Aug-15, Volume: 8, Issue:4

    Topics: Adolescent; Child; Clonazepam; Female; GABA Modulators; Humans; Male; Polysomnography; Sleep Wake Di

2012
Misleading effects of clonazepam in symptomatic electrical status epilepticus during sleep syndrome.
    Pediatric neurology, 2006, Volume: 34, Issue:2

    Topics: Anticonvulsants; Child; Clonazepam; Cognition Disorders; Electroencephalography; Humans; Male; Motor

2006
[Treatment of nocturnal myoclonus].
    Harefuah, 1983, Oct-16, Volume: 105, Issue:8

    Topics: Adult; Clonazepam; Female; Humans; Male; Middle Aged; Myoclonus; Sleep Wake Disorders

1983
Two cases of premenstrual sleep terrors and injurious sleep-walking.
    Journal of psychosomatic obstetrics and gynaecology, 1995, Volume: 16, Issue:2

    Topics: Adolescent; Clonazepam; Combined Modality Therapy; Female; Humans; Hypnosis; Middle Aged; Polysomnog

1995
Successful treatment of night terrors and somnambulism with paroxetine.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:4

    Topics: Clonazepam; Drug Therapy, Combination; Female; Humans; Middle Aged; Paroxetine; Polysomnography; Sle

1994
Rapid eye movement sleep behaviour disorder in a Chinese male.
    The Australian and New Zealand journal of psychiatry, 1994, Volume: 28, Issue:1

    Topics: Age Factors; Aged; Brain Diseases; Clonazepam; Dreams; Humans; Male; Sex Factors; Sleep Wake Disorde

1994
Conversion disorder revisited: severe parasomnia discovered.
    The Australian and New Zealand journal of psychiatry, 1993, Volume: 27, Issue:4

    Topics: Arousal; Cerebral Cortex; Clonazepam; Combat Disorders; Conversion Disorder; Dreams; Evoked Potentia

1993
Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behaviour disorder.
    Neurology, 1996, Volume: 46, Issue:2

    Topics: Brain; Clonazepam; Electromyography; Follow-Up Studies; GABA Modulators; Humans; Magnetic Resonance

1996
Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behaviour disorder.
    Neurology, 1996, Volume: 46, Issue:2

    Topics: Brain; Clonazepam; Electromyography; Follow-Up Studies; GABA Modulators; Humans; Magnetic Resonance

1996
Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behaviour disorder.
    Neurology, 1996, Volume: 46, Issue:2

    Topics: Brain; Clonazepam; Electromyography; Follow-Up Studies; GABA Modulators; Humans; Magnetic Resonance

1996
Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behaviour disorder.
    Neurology, 1996, Volume: 46, Issue:2

    Topics: Brain; Clonazepam; Electromyography; Follow-Up Studies; GABA Modulators; Humans; Magnetic Resonance

1996
Forensic sleep medicine: nocturnal wandering and violence.
    Sleep, 1995, Volume: 18, Issue:9

    Topics: Adolescent; Adult; Benzodiazepines; Clonazepam; Electroencephalography; Electromyography; Female; Fo

1995
A polysomnographically documented case of adult somnambulism with long-distance automobile driving and frequent nocturnal violence: parasomnia with continuing danger as a noninsane automatism?
    Sleep, 1995, Volume: 18, Issue:9

    Topics: Adult; Age of Onset; Anticonvulsants; Automobile Driving; Clonazepam; Forensic Medicine; Humans; Mal

1995
Sleep impairment and daytime sleepiness in later life.
    The American journal of psychiatry, 1996, Volume: 153, Issue:7

    Topics: Aged; Clonazepam; Diagnosis, Differential; Humans; Male; Polysomnography; Positive-Pressure Respirat

1996
REM sleep behaviour disorder: a treatable cause of falls in elderly people.
    Age and ageing, 1997, Volume: 26, Issue:1

    Topics: Accidental Falls; Aged; Clonazepam; Diagnosis, Differential; Female; Geriatric Assessment; Humans; P

1997
[Atypical benign partial epilepsy of childhood. Clinical follow-up EEG study of 3 patients].
    Revista de neurologia, 1998, Volume: 26, Issue:150

    Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Electroencephalography; Epilepsies, Pa

1998
[Behavior disorder of the REM sleep in 2 documented cases with polysomnography].
    Revista medica de Chile, 1999, Volume: 127, Issue:1

    Topics: Aged; Anticonvulsants; Clonazepam; Female; Humans; Male; Middle Aged; Polysomnography; Sleep Wake Di

1999
Comparative trial of valproate sodium and clonazepam in chronic epilepsy.
    Archives of neurology, 1979, Volume: 36, Issue:5

    Topics: Adult; Ataxia; Benzodiazepinones; Chronic Disease; Clonazepam; Drug Therapy, Combination; Epilepsy;

1979
Injurious sleep behavior disorders (parasomnias) affecting patients on intensive care units.
    Intensive care medicine, 1991, Volume: 17, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Clonazepam; Female; Humans; Intensive Care Units; Male; Middle Aged;

1991
Polysomnography in idiopathic muscle pain syndrome (fibrositis).
    Arquivos de neuro-psiquiatria, 1991, Volume: 49, Issue:4

    Topics: Alprazolam; Amitriptyline; Clonazepam; Electroencephalography; Fatigue Syndrome, Chronic; Female; Fi

1991
Sleep disorders and aging.
    The New England journal of medicine, 1991, Mar-07, Volume: 324, Issue:10

    Topics: Aged; Aging; Clonazepam; Estrogens; Female; Humans; Sleep Wake Disorders

1991
[Parasomnia associated with abnormal REM sleep in the aged].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1990, Volume: 92, Issue:4

    Topics: Aged; Clonazepam; Electroencephalography; Electromyography; Electrooculography; Female; Humans; Male

1990
A polysomnographic and clinical report on sleep-related injury in 100 adult patients.
    The American journal of psychiatry, 1989, Volume: 146, Issue:9

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clonazepam; Dissociative Disorders; Female; Humans

1989
Magnetic resonance findings in REM sleep behavior disorder.
    Neurology, 1989, Volume: 39, Issue:11

    Topics: Aged; Clonazepam; Electrocardiography; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged

1989
Periodic leg movement, sleep fragmentation and central sleep apnoea in two cases: reduction with Clonazepam.
    The European respiratory journal, 1988, Volume: 1, Issue:8

    Topics: Adult; Clonazepam; Female; Humans; Leg; Male; Middle Aged; Myoclonus; Sleep Apnea Syndromes; Sleep W

1988
Rapid eye movement sleep behavior disorder. A treatable parasomnia affecting older adults.
    JAMA, 1987, Apr-03, Volume: 257, Issue:13

    Topics: Aged; Behavior; Clonazepam; Electroencephalography; Electromyography; Evoked Potentials; Female; Hum

1987
Clonazepam monotherapy for epilepsy in childhood.
    Brain & development, 1985, Volume: 7, Issue:6

    Topics: Adolescent; Ataxia; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Electroencephalography;

1985
A hypernychthemeral sleep-wake syndrome: a treatment attempt.
    Chronobiology international, 1985, Volume: 2, Issue:4

    Topics: Adult; Circadian Rhythm; Clonazepam; Depression; Fatigue; Humans; Male; Sleep Wake Disorders

1985
Paroxysmal awakenings from sleep associated with excessive daytime somnolence: a form of nocturnal epilepsy.
    Neurology, 1986, Volume: 36, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Arousal; Clonazepam; Electroencephalography; Epilepsy; Female; H

1986
Familial nocturnal cramping.
    Sleep, 1986, Volume: 9, Issue:1

    Topics: Adult; Child; Child, Preschool; Clonazepam; Electroencephalography; Electromyography; Evoked Potenti

1986
Periodic leg movements in sleep: effect of clonazepam treatment.
    Neurology, 1985, Volume: 35, Issue:3

    Topics: Adult; Aged; Benzodiazepinones; Clonazepam; Disorders of Excessive Somnolence; Electroencephalograph

1985