clonazepam has been researched along with Serotonin Syndrome in 2 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serotonin syndrome and neuroleptic malignant syndrome are two drug toxidromes that have often overlapping and confusing clinical pictures." | 2.50 | Serotonin syndrome versus neuroleptic malignant syndrome: a challenging clinical quandary. ( Ambaliya, A; Dosi, R; Joshi, H; Patell, R, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dosi, R | 1 |
| Ambaliya, A | 1 |
| Joshi, H | 1 |
| Patell, R | 1 |
| Murray, KL | 1 |
| Miller, KM | 1 |
| Pearson, DL | 1 |
1 review available for clonazepam and Serotonin Syndrome
| Article | Year |
|---|---|
Serotonin syndrome versus neuroleptic malignant syndrome: a challenging clinical quandary.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Clonazepam; Diagnosis, Differential; GABA M | 2014 |
1 other study available for clonazepam and Serotonin Syndrome
| Article | Year |
|---|---|
Neonatal withdrawal syndrome following in utero exposure to paroxetine, clonazepam and olanzapine.
Topics: Antidepressive Agents, Second-Generation; Benzodiazepines; Clonazepam; Humans; Infant, Newborn; Male | 2007 |