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clonazepam and Seizures, Febrile

clonazepam has been researched along with Seizures, Febrile in 9 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Seizures, Febrile: Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)

Research Excerpts

ExcerptRelevanceReference
" The administration of two antiepileptic drugs, Sodium Valproate and Clonazepam, reduces significantly seizures occurrence compared with unmedicated controls."5.05[DPA and clonazepam activity in febrile convulsions: preliminary results]. ( Florio, C; Sorge, F; Steardo, L; Steardo, R, 1980)
"We describe a rare case of Influenza B-associated encephalopathy with hemorrhagic lesions of the corpus callosum."1.36[Hemorrhagic lesion of the corpus callosum in influenza-associated encephalitis]. ( Burillon, M; Chaix, Y; Cheuret, E, 2010)
"Clonazepam was administered rectally to six children aged 1."1.27Plasma concentrations of clonazepam after single rectal administration. ( Cherry, RC; Cullen, RE; Poulton, J; Rylance, GW, 1986)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burillon, M1
Cheuret, E1
Chaix, Y1
Riedl, B1
Steardo, L1
Florio, C1
Sorge, F1
Steardo, R1
Julien, RM1
Fowler, GW1
Pitruzzella, E1
Spina, A1
Re, G1
Scalisi, D1
Balsano, M1
Mattigk, G1
Arcas Martinez, J1
Martinez Bermejo, A1
Gonzales Gonzales, L1
Lopez Martin, V1
Pascual-Castroviejo, I1
Rylance, GW1
Poulton, J1
Cherry, RC1
Cullen, RE1
Herranz Fernández, JL1

Reviews

1 review available for clonazepam and Seizures, Febrile

ArticleYear
[Current therapy of febrile convulsions].
    Kinderarztliche Praxis, 1992, Volume: 60, Issue:4-5

    Topics: Adolescent; Adult; Child; Child, Preschool; Clonazepam; Diazepam; Humans; Infant; Seizures, Febrile

1992

Trials

1 trial available for clonazepam and Seizures, Febrile

ArticleYear
[DPA and clonazepam activity in febrile convulsions: preliminary results].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Jun-15, Volume: 56, Issue:11

    Topics: Benzodiazepinones; Child, Preschool; Clinical Trials as Topic; Clonazepam; Humans; Infant; Receptors

1980

Other Studies

7 other studies available for clonazepam and Seizures, Febrile

ArticleYear
[Hemorrhagic lesion of the corpus callosum in influenza-associated encephalitis].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17, Issue:5

    Topics: Acyclovir; Anticonvulsants; Antiviral Agents; Child; Clonazepam; Corpus Callosum; Encephalitis, Vira

2010
[A common emergency in childhood. Febrile convulsions -- what to do?].
    MMW Fortschritte der Medizin, 2003, Feb-27, Volume: 145, Issue:9

    Topics: Acetaminophen; Administration, Rectal; Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Clona

2003
A comparative study of the efficacy of newer antiepiletpic drugs on experimentally-induced febrile convulsions.
    Neuropharmacology, 1977, Volume: 16, Issue:11

    Topics: Animals; Anticonvulsants; Body Temperature; Carbamazepine; Clonazepam; Male; Mice; Phenobarbital; Se

1977
[Further statistical study of simple febrile convulsions in childhood].
    La Pediatria, 1979, Dec-31, Volume: 87, Issue:4

    Topics: Age Factors; Child; Child, Preschool; Clonazepam; Humans; Infant; Italy; Seizures; Seizures, Febrile

1979
Intermittent treatment with clonazepam in simple febrile seizures.
    Brain & development, 1990, Volume: 12, Issue:2

    Topics: Child, Preschool; Clonazepam; Female; Follow-Up Studies; Humans; Infant; Male; Seizures, Febrile

1990
Plasma concentrations of clonazepam after single rectal administration.
    Archives of disease in childhood, 1986, Volume: 61, Issue:2

    Topics: Benzodiazepinones; Child, Preschool; Clonazepam; Drug Administration Schedule; Female; Humans; Infan

1986
[Convulsive crises in childhood].
    Anales espanoles de pediatria, 1985, Volume: 23, Issue:8

    Topics: Clonazepam; Crying; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Mi

1985