clonazepam has been researched along with Recrudescence in 34 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the efficacy of clonazepam in chest pain patients with panic disorder and normal coronary arteries." | 9.09 | Clonazepam treatment of panic disorder in patients with recurrent chest pain and normal coronary arteries. ( Beitman, B; Dawaher, R; Maddock, R; Wells, VE; Wulsin, LR, 1999) |
| "The authors describe the first five patients enrolled in an open clinical trial of clonazepam as a maintenance treatment in lithium-refractory bipolar disorder." | 9.06 | Clonazepam treatment of five lithium-refractory patients with bipolar disorder. ( Aronson, TA; Hirschowitz, J; Shukla, S, 1989) |
| "On the ninth day of ziprasidone administration, galactorrhea appeared." | 7.73 | Ziprasidone-induced galactorrhea: a case report. ( Bares, M; Kopecek, M; Mohr, P, 2005) |
| "Seventeen children (age range 2 weeks to 15 years) who developed status epilepticus were treated with intravenous clonazepam (Rivotril)." | 7.66 | Intravenous clonazepam in the treatment of status epilepticus in children. ( Congdon, PJ; Forsythe, WI, 1980) |
| "Immediate EEG changes after intravenous administration of clonazepam and a correlation between the EEG changes and the effect of oral administration of the drug were studied in 21 children with minor seizures whose interictal EEG showed a paroxysmal abnormality." | 7.66 | Immediate changes of the electroencephalograms after intravenous injection of clonazepam and their relation to its effect on clinical fits in children with minor seizures. ( Iinuma, K; Onuma, A; Otomo, H; Takamatsu, N; Tamahashi, S, 1978) |
| "Cyclic coma in a 4-year-old boy followed an ingestion of clonazepam, a new benzodiazepine, utilized in treatment of convulsive disorders." | 7.65 | Clonazepam overdose resulting in cyclic coma. ( Hammond, K; Rumack, BH; Welch, TR, 1977) |
| "Treatment with clonazepam predicts lower relapse when compared with paroxetine." | 6.84 | A 6-Year Posttreatment Follow-up of Panic Disorder Patients: Treatment With Clonazepam Predicts Lower Recurrence Than Treatment With Paroxetine. ( Amrein, R; Arias-Carrión, O; Carta, MG; Dias, GP; Freire, RC; Machado, S; Mochcovitch, MD; Nardi, AE; Versiani, M, 2017) |
| "Determination of neurophysiological features of the disease course in patients with paroxysmal atrial fibrillation (AF); pathogenetic validation of use and assessment of therapeutic efficacy of clonazepam (an atypical agonist of benzodiazepine receptors) in combined antiarrhythmic therapy." | 5.12 | [New facts about pathogenesis of atrial fibrillation: correlation between changes in bioelectric brain activity and recurrence of atrial fibrillation paroxysms]. ( Fedorova, VI; Gordeev, SA; Nedostup, AV; Vasiukov, SS, 2007) |
| "To examine the efficacy of clonazepam in chest pain patients with panic disorder and normal coronary arteries." | 5.09 | Clonazepam treatment of panic disorder in patients with recurrent chest pain and normal coronary arteries. ( Beitman, B; Dawaher, R; Maddock, R; Wells, VE; Wulsin, LR, 1999) |
| "The authors describe the first five patients enrolled in an open clinical trial of clonazepam as a maintenance treatment in lithium-refractory bipolar disorder." | 5.06 | Clonazepam treatment of five lithium-refractory patients with bipolar disorder. ( Aronson, TA; Hirschowitz, J; Shukla, S, 1989) |
| ", carbamazepine, valproate, clonazepam, oxcarbazepine, and electroconvulsive therapy (ECT), for patients with bipolar disorder." | 4.78 | Anticonvulsants in the treatment of bipolar disorder. ( Keck, PE; McElroy, SL; Nemeroff, CB, 1992) |
| "On the ninth day of ziprasidone administration, galactorrhea appeared." | 3.73 | Ziprasidone-induced galactorrhea: a case report. ( Bares, M; Kopecek, M; Mohr, P, 2005) |
| "Topiramate is a novel anticonvulsant agent with a broad spectrum mechanism of action, and recent clinical reports indicate that it may have mood stabilizing properties in bipolar disorder." | 3.71 | Topiramate as a mood stabilizer. ( Kasper, S; Letmaier, M; Schreinzer, D; Wolf, R, 2001) |
| "Seventeen children (age range 2 weeks to 15 years) who developed status epilepticus were treated with intravenous clonazepam (Rivotril)." | 3.66 | Intravenous clonazepam in the treatment of status epilepticus in children. ( Congdon, PJ; Forsythe, WI, 1980) |
| "Immediate EEG changes after intravenous administration of clonazepam and a correlation between the EEG changes and the effect of oral administration of the drug were studied in 21 children with minor seizures whose interictal EEG showed a paroxysmal abnormality." | 3.66 | Immediate changes of the electroencephalograms after intravenous injection of clonazepam and their relation to its effect on clinical fits in children with minor seizures. ( Iinuma, K; Onuma, A; Otomo, H; Takamatsu, N; Tamahashi, S, 1978) |
| "Cyclic coma in a 4-year-old boy followed an ingestion of clonazepam, a new benzodiazepine, utilized in treatment of convulsive disorders." | 3.65 | Clonazepam overdose resulting in cyclic coma. ( Hammond, K; Rumack, BH; Welch, TR, 1977) |
| "Treatment with clonazepam predicts lower relapse when compared with paroxetine." | 2.84 | A 6-Year Posttreatment Follow-up of Panic Disorder Patients: Treatment With Clonazepam Predicts Lower Recurrence Than Treatment With Paroxetine. ( Amrein, R; Arias-Carrión, O; Carta, MG; Dias, GP; Freire, RC; Machado, S; Mochcovitch, MD; Nardi, AE; Versiani, M, 2017) |
| "Benzodiazepine withdrawal symptoms were also measured." | 2.69 | Discontinuation of clonazepam in the treatment of social phobia. ( Book, SW; Colket, JT; Connor, KM; Davidson, JR; Ferrell, F; Malik, ML; Miner, CM; Potts, NL; Tupler, LA, 1998) |
| " Finally, the authors discuss general issues concerning the relapse of patients upon drug discontinuation, the long-term use of benzodiazepines, and other important issues concerning the use of these agents for the treatment of social phobia." | 2.39 | Treatment of social phobia with benzodiazepines. ( Davidson, JR; Potts, NL; Tupler, LA, 1994) |
| "Risperidone treatment was begun (1mg/d and 1." | 1.39 | [Follow-up of a 16-year-old adolescent with early-onset schizophrenia and catatonic symptoms]. ( Askenazy, F; Drici, M; Lavrut, T; Menard, ML; Yagoubi, F, 2013) |
| "Treatment with clonazepam was very effective; it completely ameliorated the symptom of tongue biting but had no effect on chin trembling." | 1.33 | Recurrent nocturnal tongue biting in a child with hereditary chin trembling. ( Goraya, JS; Parmar, V; Virdi, V, 2006) |
| "We report 170 cases of perineal neuralgia due to pudendal nerve compression within Alcock canal or by ischiatic spine." | 1.30 | [Treatments of perineal neuralgia caused by involvement of the pudendal nerve]. ( Amarenco, G; Bosc, S; Bouju, P; Cocquen, AL; Goldet, R; Kerdraon, J; Le Budet, C, 1997) |
| "Clonazepam is a high-potency 1,4-benzodiazepine derivative with an intermediate to long elimination half-life that is used mainly in neurology as an antiepileptic." | 1.27 | Clonazepam in the treatment of patients with recurrent panic attacks. ( Annable, L; Beaudry, P; Chouinard, G; Fontaine, R, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (26.47) | 18.7374 |
| 1990's | 9 (26.47) | 18.2507 |
| 2000's | 8 (23.53) | 29.6817 |
| 2010's | 8 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freire, RC | 1 |
| Amrein, R | 1 |
| Mochcovitch, MD | 1 |
| Dias, GP | 1 |
| Machado, S | 1 |
| Versiani, M | 1 |
| Arias-Carrión, O | 1 |
| Carta, MG | 1 |
| Nardi, AE | 1 |
| Danish, N | 1 |
| Khawaja, IS | 1 |
| Schenck, CH | 1 |
| Lagrand, T | 1 |
| Winogrodzka, A | 1 |
| Murphy, RA | 1 |
| Hallahan, B | 1 |
| Barańska-Rybak, W | 1 |
| Błażewicz, I | 1 |
| Kąkol, M | 1 |
| Roter, M | 1 |
| Nowicki, R | 1 |
| Chèze, M | 1 |
| Muckensturm, A | 1 |
| Hoizey, G | 1 |
| Pépin, G | 1 |
| Deveaux, M | 1 |
| Lin, HY | 1 |
| Lin, CC | 1 |
| Liu, CC | 1 |
| Menard, ML | 1 |
| Yagoubi, F | 1 |
| Drici, M | 1 |
| Lavrut, T | 1 |
| Askenazy, F | 1 |
| Lerner, AG | 1 |
| Gelkopf, M | 1 |
| Skladman, I | 1 |
| Rudinski, D | 1 |
| Nachshon, H | 1 |
| Bleich, A | 1 |
| Riedl, B | 1 |
| Mashiko, H | 1 |
| Kurita, M | 1 |
| Shirakawa, H | 1 |
| Ohtomo, K | 1 |
| Hashimoto, M | 1 |
| Miyashita, N | 1 |
| Niwa, S | 1 |
| Kopecek, M | 1 |
| Bares, M | 1 |
| Mohr, P | 1 |
| Goraya, JS | 1 |
| Virdi, V | 1 |
| Parmar, V | 1 |
| Trajanovic, NN | 1 |
| Shapiro, CM | 1 |
| Ong, A | 1 |
| Nedostup, AV | 1 |
| Vasiukov, SS | 1 |
| Fedorova, VI | 1 |
| Gordeev, SA | 1 |
| Chouinard, G | 3 |
| Labonte, A | 1 |
| Fontaine, R | 3 |
| Annable, L | 3 |
| Congdon, PJ | 1 |
| Forsythe, WI | 1 |
| Davidson, JR | 2 |
| Tupler, LA | 2 |
| Potts, NL | 2 |
| Amarenco, G | 1 |
| Kerdraon, J | 1 |
| Bouju, P | 1 |
| Le Budet, C | 1 |
| Cocquen, AL | 1 |
| Bosc, S | 1 |
| Goldet, R | 1 |
| Stein, MB | 1 |
| Connor, KM | 1 |
| Miner, CM | 1 |
| Malik, ML | 1 |
| Book, SW | 1 |
| Colket, JT | 1 |
| Ferrell, F | 1 |
| Wulsin, LR | 1 |
| Maddock, R | 1 |
| Beitman, B | 1 |
| Dawaher, R | 1 |
| Wells, VE | 1 |
| Boshes, RA | 1 |
| Afonso, JA | 1 |
| Tanev, K | 1 |
| Letmaier, M | 1 |
| Schreinzer, D | 1 |
| Wolf, R | 1 |
| Kasper, S | 1 |
| Livingston, S | 1 |
| Iinuma, K | 1 |
| Tamahashi, S | 1 |
| Otomo, H | 1 |
| Onuma, A | 1 |
| Takamatsu, N | 1 |
| Stern, M | 1 |
| Lagenstein, I | 1 |
| Welch, TR | 1 |
| Rumack, BH | 1 |
| Hammond, K | 1 |
| Keck, PE | 1 |
| McElroy, SL | 1 |
| Nemeroff, CB | 1 |
| Sachs, GS | 1 |
| Hakeem, VF | 1 |
| Wallace, SJ | 1 |
| Aronson, TA | 1 |
| Shukla, S | 1 |
| Hirschowitz, J | 1 |
| Beaudry, P | 2 |
3 reviews available for clonazepam and Recrudescence
| Article | Year |
|---|---|
Treatment of social phobia with benzodiazepines.
Topics: Alprazolam; Benzodiazepines; Clinical Trials as Topic; Clonazepam; Double-Blind Method; Humans; Phob | 1994 |
Medication treatments for panic disorder and social phobia.
Topics: Antidepressive Agents, Tricyclic; Benzamides; Benzodiazepines; Citalopram; Clinical Trials as Topic; | 1998 |
Anticonvulsants in the treatment of bipolar disorder.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clonazepam; Drug Therapy, Combination; Electroconv | 1992 |
8 trials available for clonazepam and Recrudescence
| Article | Year |
|---|---|
A 6-Year Posttreatment Follow-up of Panic Disorder Patients: Treatment With Clonazepam Predicts Lower Recurrence Than Treatment With Paroxetine.
Topics: Adult; Clonazepam; Female; Follow-Up Studies; GABA Modulators; Humans; Male; Middle Aged; Panic Diso | 2017 |
Clonazepam treatment of lysergic acid diethylamide-induced hallucinogen persisting perception disorder with anxiety features.
Topics: Adolescent; Adult; Anxiety; Clonazepam; Drug Administration Schedule; Female; GABA Modulators; Hallu | 2003 |
[New facts about pathogenesis of atrial fibrillation: correlation between changes in bioelectric brain activity and recurrence of atrial fibrillation paroxysms].
Topics: Amiodarone; Anti-Arrhythmia Agents; Anticonvulsants; Atrial Fibrillation; Beta Rhythm; Brain; Clonaz | 2007 |
New concepts in benzodiazepine therapy: rebound anxiety and new indications for the more potent benzodiazepines.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Bipolar Disorder; Bromazepam; C | 1983 |
Discontinuation of clonazepam in the treatment of social phobia.
Topics: Adult; Anticonvulsants; Clonazepam; Dose-Response Relationship, Drug; Double-Blind Method; Drug Admi | 1998 |
Clonazepam treatment of panic disorder in patients with recurrent chest pain and normal coronary arteries.
Topics: Chest Pain; Clonazepam; Coronary Vessels; Double-Blind Method; Follow-Up Studies; GABA Modulators; H | 1999 |
Clonazepam treatment of five lithium-refractory patients with bipolar disorder.
Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Clonazepam; Drug Therapy, Combination; Female; Hu | 1989 |
An open clinical trial of clonazepam in the treatment of patients with recurrent panic attacks.
Topics: Adult; Anxiety; Benzodiazepinones; Clinical Trials as Topic; Clonazepam; Fear; Female; Humans; Male; | 1985 |
23 other studies available for clonazepam and Recrudescence
| Article | Year |
|---|---|
Violent Parasomnia With Recurrent Biting and Surgical Interventions: Case Report and Differential Diagnosis.
Topics: Bites, Human; Clonazepam; Combined Modality Therapy; Continuous Positive Airway Pressure; Diagnosis, | 2018 |
Late relapse myoclonus in a case of Lance-Adams syndrome.
Topics: Aged; Clonazepam; Humans; Hypoxia, Brain; Male; Myoclonus; Recurrence; Syndrome | 2013 |
Psychosis improved dysphonia.
Topics: Acute Disease; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Clonazepam; Diagnosis, Differential | 2013 |
Cutaneous manifestations of injectable drug use: hidden secrets.
Topics: Abscess; Clonazepam; Diagnosis, Differential; Humans; Male; Opipramol; Recurrence; Risk Factors; Ski | 2014 |
A tendency for re-offending in drug-facilitated crime.
Topics: Adult; Anti-Anxiety Agents; Chromatography, Liquid; Clonazepam; Crime Victims; Doxylamine; Drug Comb | 2010 |
Hypomania associated with adjunctive aripiprazole in an elder female with recurrent major depressive disorder: dose-related phenomenon?
Topics: Aripiprazole; Bipolar Disorder; Clonazepam; Depressive Disorder, Major; Dose-Response Relationship, | 2012 |
[Follow-up of a 16-year-old adolescent with early-onset schizophrenia and catatonic symptoms].
Topics: Adolescent; Benzodiazepines; Carbamazepine; Clonazepam; Clozapine; Creatine Kinase; Diagnosis, Diffe | 2013 |
[A common emergency in childhood. Febrile convulsions -- what to do?].
Topics: Acetaminophen; Administration, Rectal; Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Clona | 2003 |
Case of bipolar disorder successfully stabilized with clonazepam, valproate and lithium after numerous relapses for 47 years.
Topics: Aged; Antimanic Agents; Bipolar Disorder; Clonazepam; Drug Resistance; Drug Therapy, Combination; Fe | 2004 |
Ziprasidone-induced galactorrhea: a case report.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Clonazepam; Depressive Disorder, Major; Female; Galact | 2005 |
Recurrent nocturnal tongue biting in a child with hereditary chin trembling.
Topics: Anticonvulsants; Chin; Clonazepam; Female; Genes, Dominant; Humans; Infant; Male; Parasomnias; Pedig | 2006 |
Atypical presentation of NREM arousal parasomnia with repetitive episodes.
Topics: Adult; Brain; Clonazepam; Diagnosis, Differential; Electroencephalography; Evoked Potentials; Family | 2007 |
Intravenous clonazepam in the treatment of status epilepticus in children.
Topics: Adolescent; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Diazepam; Electroencephalography | 1980 |
[Treatments of perineal neuralgia caused by involvement of the pudendal nerve].
Topics: Administration, Topical; Anti-Inflammatory Agents; Clonazepam; Dexamethasone; Electric Stimulation T | 1997 |
Treatment of Meige's syndrome with ECT.
Topics: Anxiety Disorders; Baclofen; Clonazepam; Combined Modality Therapy; Comorbidity; Depressive Disorder | 1999 |
Topiramate as a mood stabilizer.
Topics: Acute Disease; Adaptation, Psychological; Adult; Antimanic Agents; Bipolar Disorder; Clonazepam; Dos | 2001 |
Medical treatment of epilepsy: part I.
Topics: Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combina | 1978 |
Immediate changes of the electroencephalograms after intravenous injection of clonazepam and their relation to its effect on clinical fits in children with minor seizures.
Topics: Administration, Oral; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Electroencephalography | 1978 |
[Hypsarrhythmia as a cause of recurrent infantile apnoea (author's transl)].
Topics: Apnea; Bronchitis; Clonazepam; Electroencephalography; Female; Humans; Infant; Recurrence; Spasms, I | 1979 |
Clonazepam overdose resulting in cyclic coma.
Topics: Benzodiazepinones; Child, Preschool; Clonazepam; Coma; Humans; Male; Recurrence | 1977 |
Use of clonazepam for bipolar affective disorder.
Topics: Acute Disease; Adult; Antipsychotic Agents; Bipolar Disorder; Clonazepam; Drug Therapy, Combination; | 1990 |
EEG monitoring of therapy for neonatal seizures.
Topics: Anticonvulsants; Chloral Hydrate; Clonazepam; Diazepam; Drug Therapy, Combination; Electroencephalog | 1990 |
Clonazepam in the treatment of patients with recurrent panic attacks.
Topics: Adult; Agoraphobia; Anxiety Disorders; Benzodiazepinones; Clonazepam; Drug Evaluation; Fear; Female; | 1986 |