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clonazepam and Paraparesis, Tropical Spastic

clonazepam has been researched along with Paraparesis, Tropical Spastic in 1 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Paraparesis, Tropical Spastic: A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)

Research Excerpts

ExcerptRelevanceReference
"Periodic movements in sleep (nocturnal myoclonus) are characterized by a triple flexion of the ankle, knee and hip, which are particularly evident during 1-2 and 2-3 sleep stages."2.38[Movement disorders in HTLV-I associated myelopathy (HAM)]. ( Maruyama, S; Osawa, M, 1993)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Osawa, M1
Maruyama, S1

Reviews

1 review available for clonazepam and Paraparesis, Tropical Spastic

ArticleYear
[Movement disorders in HTLV-I associated myelopathy (HAM)].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:11

    Topics: Clonazepam; Diagnosis, Differential; Electromyography; Humans; Levodopa; Myoclonus; Paraparesis, Tro

1993