clonazepam has been researched along with Orthostatic Intolerance in 2 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Orthostatic Intolerance: Symptoms of cerebral hypoperfusion or autonomic overaction which develop while the subject is standing, but are relieved on recumbency. Types of this include NEUROCARDIOGENIC SYNCOPE; POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME; and neurogenic ORTHOSTATIC HYPOTENSION. (From Noseworthy, JH., Neurological Therapeutics Principles and Practice, 2007, p2575-2576)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Orthostatic tremor is characterised by a feeling of unsteadiness that is accompanied by a high frequency (13-18 Hz) tremor of the legs when standing, and which is relieved by sitting or walking." | 1.37 | Orthostatic tremor. ( Bain, PG; Jones, L, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tijero, B | 1 |
| Gómez-Esteban, JC | 1 |
| Berganzo, K | 1 |
| Zarranz, JJ | 1 |
| Jones, L | 1 |
| Bain, PG | 1 |
2 other studies available for clonazepam and Orthostatic Intolerance
| Article | Year |
|---|---|
[REM sleep behaviour disorder and "pure" autonomic failure. Presentation of two cases].
Topics: Aged; Clonazepam; Female; GABA Modulators; Heart; Heart Rate; Humans; Magnetic Resonance Imaging; Ma | 2012 |
Orthostatic tremor.
Topics: Aged; Clonazepam; GABA Modulators; Humans; Male; Myocardial Infarction; Neurologic Examination; Orth | 2011 |