clonazepam has been researched along with Orphan Diseases in 3 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Orphan Diseases: Rare diseases that have not been well studied.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In symptomatic paroxysmal dyskinesias, the treatment of the underlying disease will provide best results." | 2.47 | Treatment of paroxysmal dyskinesias. ( Bürk, K; Oertel, WH; Strzelczyk, A, 2011) |
| "The four classic categories of paroxysmal dyskinesias are kinesigenic, nonkinesigenic, exercise-induced and hypnogenic." | 1.40 | A rare paroxysmal movement disorder: mixed type of paroxysmal dyskinesia. ( Arpaci, B; Atakli, D; Guresci, B; Sen, A, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rønne, MS | 1 |
| Nielsen, PB | 1 |
| Mogensen, CB | 1 |
| Sen, A | 1 |
| Atakli, D | 1 |
| Guresci, B | 1 |
| Arpaci, B | 1 |
| Strzelczyk, A | 1 |
| Bürk, K | 1 |
| Oertel, WH | 1 |
1 review available for clonazepam and Orphan Diseases
| Article | Year |
|---|---|
Treatment of paroxysmal dyskinesias.
Topics: Anticonvulsants; Carbamazepine; Chorea; Clonazepam; Humans; Rare Diseases | 2011 |
2 other studies available for clonazepam and Orphan Diseases
| Article | Year |
|---|---|
[Stiff baby syndrome is a rare cause of neonatal hypertonicity].
Topics: Anticonvulsants; Clonazepam; Female; Humans; Infant, Newborn; Rare Diseases; Stiff-Person Syndrome | 2014 |
A rare paroxysmal movement disorder: mixed type of paroxysmal dyskinesia.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Chorea; Clonazepam; Diagnosis, Differential; Drug Therap | 2014 |