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clonazepam and Neurodegenerative Diseases

clonazepam has been researched along with Neurodegenerative Diseases in 10 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research Excerpts

ExcerptRelevanceReference
"Sleep disorders and neurodegenerative diseases are commonly encountered in primary care."2.53Importance of Rapid Eye Movement Sleep Behavior Disorder to the Primary Care Physician. ( Howell, MJ; McCarter, SJ, 2016)
"The cornerstone of treatment for all parasomnias is adequate patient and bed partner education."2.46Parasomnias: an overview. ( Lee-Chiong, T; Matwiyoff, G, 2010)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's7 (70.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rémi, J1
Fernández-Arcos, A1
Iranzo, A2
Serradell, M1
Gaig, C1
Santamaria, J2
McCarter, SJ1
Howell, MJ1
Shimohata, T1
Inoue, Y1
Hirata, K1
Abenza Abildúa, MJ1
Miralles Martinez, A1
Arpa Gutiérrez, FJ1
Lores Gutiérrez, V1
Algarra Lucas, C1
Jimeno Montero, C1
Sánchez García, B1
Mata Álvarez-Santullano, M1
Borrue Fernández, C1
Cordero Martín, G1
Gutiérrez Cueto, G1
Torrecillas Narváez, MD1
Thuissard Vasallo, I1
Gómez Aceña, A1
Tolosa, E1
Bodkin, CL1
Schenck, CH1
Lauterbach, EC1
Victoroff, J1
Coburn, KL1
Shillcutt, SD1
Doonan, SM1
Mendez, MF1
Matwiyoff, G1
Lee-Chiong, T1
Yamashita, S1
Maeda, Y1
Ohmori, H1
Uchida, Y1
Hirano, T1
Yonemura, K1
Uyama, E1
Uchino, M1

Reviews

7 reviews available for clonazepam and Neurodegenerative Diseases

ArticleYear
[Wild dreams and injured bed partners - The REM-sleep-behavior disorder as a precursor of neurodegenerative disorders].
    MMW Fortschritte der Medizin, 2017, Volume: 159, Issue:15

    Topics: Aged; Clonazepam; Diagnosis, Differential; Dreams; Electroencephalography; Humans; Male; Neurodegene

2017
Importance of Rapid Eye Movement Sleep Behavior Disorder to the Primary Care Physician.
    Mayo Clinic proceedings, 2016, Volume: 91, Issue:10

    Topics: Central Nervous System Depressants; Clonazepam; Diagnosis, Differential; GABA Modulators; Humans; Me

2016
Diagnosis, disease notification, and management of rapid eye movement (REM) sleep behavior disorder.
    Rinsho shinkeigaku = Clinical neurology, 2017, 02-25, Volume: 57, Issue:2

    Topics: alpha-Synuclein; Clonazepam; Diagnosis, Differential; Humans; Neurodegenerative Diseases; REM Sleep

2017
The clinical and pathophysiological relevance of REM sleep behavior disorder in neurodegenerative diseases.
    Sleep medicine reviews, 2009, Volume: 13, Issue:6

    Topics: Anticonvulsants; Brain; Clonazepam; Dreams; Humans; Neurodegenerative Diseases; Neurotransmitter Age

2009
Rapid eye movement sleep behavior disorder in women: relevance to general and specialty medical practice.
    Journal of women's health (2002), 2009, Volume: 18, Issue:12

    Topics: Clonazepam; Diagnosis, Differential; Disease Progression; Early Diagnosis; Female; GABA Modulators;

2009
Psychopharmacological neuroprotection in neurodegenerative disease: assessing the preclinical data.
    The Journal of neuropsychiatry and clinical neurosciences, 2010,Winter, Volume: 22, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Antipsychotic Agents; Benzodiazepines; Benzo

2010
Parasomnias: an overview.
    The Indian journal of medical research, 2010, Volume: 131

    Topics: Adolescent; Adult; Age of Onset; Aged; Clonazepam; Female; Humans; Male; Mental Disorders; Middle Ag

2010

Other Studies

3 other studies available for clonazepam and Neurodegenerative Diseases

ArticleYear
The Clinical Phenotype of Idiopathic Rapid Eye Movement Sleep Behavior Disorder at Presentation: A Study in 203 Consecutive Patients.
    Sleep, 2016, Jan-01, Volume: 39, Issue:1

    Topics: Aged; Aged, 80 and over; Clonazepam; Continuous Positive Airway Pressure; Dementia; Electromyography

2016
Conditions associated with REM sleep behaviour disorder: Description of a hospital series.
    Neurologia, 2019, Volume: 34, Issue:3

    Topics: Anticonvulsants; Clonazepam; Female; Humans; Male; Middle Aged; Neurodegenerative Diseases; Polysomn

2019
Pantothenate kinase-associated neurodegeneration initially presenting as postural tremor alone in a Japanese family with homozygous N245S substitutions in the pantothenate kinase gene.
    Journal of the neurological sciences, 2004, Oct-15, Volume: 225, Issue:1-2

    Topics: Acanthocytes; Adult; Anticonvulsants; Asian People; Asparagine; Basal Ganglia; Brain Mapping; Clonaz

2004