clonazepam has been researched along with Neuralgia in 11 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the analgesic efficacy and adverse effects of the antiepileptic drug clonazepam in neuropathic pain and fibromyalgia." | 8.88 | Clonazepam for neuropathic pain and fibromyalgia in adults. ( Corrigan, R; Derry, S; Moore, RA; Wiffen, PJ, 2012) |
| "A study of 21 patients has shown that clonazepam is an effective drug in preventing attacks of pain in trigeminal neuralgia and Sluder's syndrome." | 7.65 | Clonazepam in cranial neuralgias. ( Scarlato, G; Smirne, S, 1977) |
| "To assess the analgesic efficacy and adverse effects of the antiepileptic drug clonazepam in neuropathic pain and fibromyalgia." | 4.88 | Clonazepam for neuropathic pain and fibromyalgia in adults. ( Corrigan, R; Derry, S; Moore, RA; Wiffen, PJ, 2012) |
| "We investigated the effects of OT-7100, a novel analgesic compound (5-n-butyl-7-(3,4,5-trimethoxybenzoylamino)pyrazolo[1,5-a]pyrimidi ne), on prostaglandin E2 biosynthesis in vitro, acute hyperalgesia induced by yeast and substance P in rats and hyperalgesia in rats with a chronic constriction injury to the sciatic nerve (Bennett model), which is a model for peripheral neuropathic pain." | 3.70 | The novel analgesic compound OT-7100 (5-n-butyl-7-(3,4,5-trimethoxybenzoylamino)pyrazolo[1,5-a]pyrimid ine) attenuates mechanical nociceptive responses in animal models of acute and peripheral neuropathic hyperalgesia. ( Iwamoto, T; Kohri, H; Noguchi, K; Ohara, M; Sato, S; Senba, E; Yasuda, T, 1999) |
| "A study of 21 patients has shown that clonazepam is an effective drug in preventing attacks of pain in trigeminal neuralgia and Sluder's syndrome." | 3.65 | Clonazepam in cranial neuralgias. ( Scarlato, G; Smirne, S, 1977) |
| "As in neuropathic pain, decreased brain activation to heat stimuli has been demonstrated with fMRI in BMS patients." | 2.48 | Pathophysiology of primary burning mouth syndrome. ( Jääskeläinen, SK, 2012) |
| "Like other chronic neuropathic pain conditions, PPTTN can significantly alter the patient's quality of life, especially when pharmacological treatment is ineffective or not tolerated." | 1.72 | Botulinum toxin A for management of refractory concurrent buccal and inferior alveolar nerve post-traumatic neuropathies: a case report. ( Capon, C; Crevant, A; Moreau, N; Pointin, A; Sulukdjian, A, 2022) |
| "We report 170 cases of perineal neuralgia due to pudendal nerve compression within Alcock canal or by ischiatic spine." | 1.30 | [Treatments of perineal neuralgia caused by involvement of the pudendal nerve]. ( Amarenco, G; Bosc, S; Bouju, P; Cocquen, AL; Goldet, R; Kerdraon, J; Le Budet, C, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Capon, C | 1 |
| Crevant, A | 1 |
| Pointin, A | 1 |
| Sulukdjian, A | 1 |
| Moreau, N | 1 |
| Kalladka, M | 1 |
| Nasri-Heir, C | 1 |
| Eliav, E | 1 |
| Ananthan, S | 1 |
| Viswanath, A | 1 |
| Heir, G | 1 |
| Jääskeläinen, SK | 1 |
| Corrigan, R | 1 |
| Derry, S | 1 |
| Wiffen, PJ | 1 |
| Moore, RA | 1 |
| Hugel, H | 1 |
| Ellershaw, JE | 1 |
| Dickman, A | 1 |
| Amarenco, G | 1 |
| Kerdraon, J | 1 |
| Bouju, P | 1 |
| Le Budet, C | 1 |
| Cocquen, AL | 1 |
| Bosc, S | 1 |
| Goldet, R | 1 |
| Yasuda, T | 1 |
| Iwamoto, T | 1 |
| Ohara, M | 1 |
| Sato, S | 1 |
| Kohri, H | 1 |
| Noguchi, K | 1 |
| Senba, E | 1 |
| Covington, EC | 1 |
| Smirne, S | 1 |
| Scarlato, G | 1 |
| Klein, DS | 1 |
| Schmidt, RE | 1 |
| Bouckoms, AJ | 1 |
| Litman, RE | 1 |
4 reviews available for clonazepam and Neuralgia
| Article | Year |
|---|---|
Continuous neuropathic pain secondary to endoscopic procedures: report of two cases and review of the literature.
Topics: Adult; Amines; Analgesics; Clonazepam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; GABA | 2016 |
Pathophysiology of primary burning mouth syndrome.
Topics: Anesthetics, Local; Burning Mouth Syndrome; Clonazepam; Female; Functional Neuroimaging; Humans; Lid | 2012 |
Clonazepam for neuropathic pain and fibromyalgia in adults.
Topics: Adult; Analgesics; Anticonvulsants; Clonazepam; Fibromyalgia; Humans; Neuralgia; Pain Management | 2012 |
Anticonvulsants for neuropathic pain and detoxification.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Gabapenti | 1998 |
1 trial available for clonazepam and Neuralgia
| Article | Year |
|---|---|
Clonazepam as an adjuvant analgesic in patients with cancer-related neuropathic pain.
Topics: Adult; Aged; Analgesics; Clonazepam; Female; GABA Modulators; Humans; Middle Aged; Neoplasms; Neural | 2003 |
6 other studies available for clonazepam and Neuralgia
| Article | Year |
|---|---|
Botulinum toxin A for management of refractory concurrent buccal and inferior alveolar nerve post-traumatic neuropathies: a case report.
Topics: Amitriptyline; Animals; Botulinum Toxins, Type A; Carbamazepine; Clonazepam; Duloxetine Hydrochlorid | 2022 |
[Treatments of perineal neuralgia caused by involvement of the pudendal nerve].
Topics: Administration, Topical; Anti-Inflammatory Agents; Clonazepam; Dexamethasone; Electric Stimulation T | 1997 |
The novel analgesic compound OT-7100 (5-n-butyl-7-(3,4,5-trimethoxybenzoylamino)pyrazolo[1,5-a]pyrimid ine) attenuates mechanical nociceptive responses in animal models of acute and peripheral neuropathic hyperalgesia.
Topics: Amitriptyline; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antide | 1999 |
Clonazepam in cranial neuralgias.
Topics: Adult; Aged; Benzodiazepinones; Clonazepam; Cranial Nerves; Facial Neuralgia; Female; Humans; Male; | 1977 |
Chronic headache resulting from postoperative supraorbital neuralgia.
Topics: Bupivacaine; Chronic Disease; Clonazepam; Female; Headache; Humans; Middle Aged; Nerve Block; Neural | 1991 |
Clonazepam in the treatment of neuralgic pain syndrome.
Topics: Aged; Benzodiazepinones; Clonazepam; Dose-Response Relationship, Drug; Female; Humans; Male; Middle | 1985 |