clonazepam has been researched along with Nerve Degeneration in 3 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The tremor was refractory to pharmacotherapy (clonazepam, propranolol, and levodopa), but was reduced after implantation of a thalamic stimulator device." | 1.30 | Midbrain tremor and hypertrophic olivary degeneration after pontine hemorrhage. ( Bakke, SJ; Nyberg-Hansen, R; Shepherd, GM; Tauböll, E, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marks, JD | 1 |
| Boriboun, C | 1 |
| Wang, J | 1 |
| Shepherd, GM | 1 |
| Tauböll, E | 1 |
| Bakke, SJ | 1 |
| Nyberg-Hansen, R | 1 |
| Lokensgard, JR | 1 |
| Chao, CC | 1 |
| Gekker, G | 1 |
| Hu, S | 1 |
| Peterson, PK | 1 |
1 review available for clonazepam and Nerve Degeneration
| Article | Year |
|---|---|
Benzodiazepines, glia, and HIV-1 neuropathogenesis.
Topics: AIDS Dementia Complex; Anti-HIV Agents; Benzodiazepines; Clonazepam; Diazepam; Drug Design; Gene Exp | 1998 |
2 other studies available for clonazepam and Nerve Degeneration
| Article | Year |
|---|---|
Mitochondrial nitric oxide mediates decreased vulnerability of hippocampal neurons from immature animals to NMDA.
Topics: Animals; Animals, Newborn; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultu | 2005 |
Midbrain tremor and hypertrophic olivary degeneration after pontine hemorrhage.
Topics: Adrenergic beta-Antagonists; Anticonvulsants; Antiparkinson Agents; Cerebral Hemorrhage; Clonazepam; | 1997 |