clonazepam has been researched along with Myelopathy in 8 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propriospinal myoclonus arising from a spinal generator may be facilitated by changes in supraspinal control related to vigilance levels." | 1.30 | Propriospinal myoclonus upon relaxation and drowsiness: a cause of severe insomnia. ( Liguori, R; Lugaresi, E; Montagna, P; Plazzi, G; Provini, F, 1997) |
| "Propriospinal myoclonus is a subtype of spinal myoclonus characterized by axial flexion or extension jerks, arrhythmic and prolonged muscle bursts with a pattern of activation consistent with a slow conduction within the propriospinal pathways." | 1.30 | [Propriospinal myoclonus induced by relaxation and drowsiness]. ( Arné, P; Dousset, V; Henry, P; Paty, J; Tison, F, 1998) |
| "Later in the clinical course, the myoclonus became stimulus sensitive and was induced by tendon tap given anywhere on the body, with the latency ranging from 50 to 150 ms irrespective of the sites of tapping." | 1.29 | Spinal myoclonus resembling belly dance. ( Araki, K; Kono, I; Nakajima, K; Shibasaki, H; Ueda, Y, 1994) |
| " The following were taken as evaluation criteria: age, sex, performance status, duration and dosage of previous systemic and current spinal morphine therapy, concomitant analgesic and co-analgesic medication, pretreatment of the dorsal column and neurological dysfunction due to damage either of the nerval plexus or of the medulla spinalis." | 1.29 | Complications of spinal opioid therapy: myoclonus, spastic muscle tone and spinal jerking. ( Bingel, U; Kloke, M; Seeber, S, 1994) |
| "In two, the myoclonus is associated with severe cervical spondylitis." | 1.26 | Spinal myoclonus. ( Cherington, M; Hoehn, MM, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ray, BK | 1 |
| Guha, G | 1 |
| Misra, AK | 1 |
| Das, SK | 1 |
| Kryshanovskiĭ, GN | 1 |
| Grafova, VN | 1 |
| Danilova, EI | 1 |
| Kono, I | 1 |
| Ueda, Y | 1 |
| Araki, K | 1 |
| Nakajima, K | 1 |
| Shibasaki, H | 1 |
| Kloke, M | 1 |
| Bingel, U | 1 |
| Seeber, S | 1 |
| Montagna, P | 1 |
| Provini, F | 1 |
| Plazzi, G | 1 |
| Liguori, R | 1 |
| Lugaresi, E | 1 |
| Tison, F | 1 |
| Arné, P | 1 |
| Dousset, V | 1 |
| Paty, J | 1 |
| Henry, P | 1 |
| Hoehn, MM | 1 |
| Cherington, M | 1 |
| Kida, Y | 1 |
| Sawada, T | 1 |
| Naritomi, H | 1 |
| Kuriyama, Y | 1 |
| Ogawa, M | 1 |
8 other studies available for clonazepam and Myelopathy
| Article | Year |
|---|---|
Involuntary jerking of lower half of the body (spinal myoclonus).
Topics: Baclofen; Clonazepam; Clonidine; Diagnosis, Differential; Humans; Lower Extremity; Middle Aged; Myoc | 2005 |
[Effect of benzodiazepines on neuropathologic syndromes of spinal origin].
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Myoclonus; P | 1984 |
Spinal myoclonus resembling belly dance.
Topics: Abdominal Muscles; Anterior Horn Cells; Clonazepam; Dancing; Electromyography; Humans; Male; Medulla | 1994 |
Complications of spinal opioid therapy: myoclonus, spastic muscle tone and spinal jerking.
Topics: Administration, Oral; Analgesia; Analgesia, Epidural; Baclofen; Clonazepam; Female; Humans; Infusion | 1994 |
Propriospinal myoclonus upon relaxation and drowsiness: a cause of severe insomnia.
Topics: Adult; Aged; Anticonvulsants; Arachnoid Cysts; Arousal; Clonazepam; Humans; Magnetic Resonance Imagi | 1997 |
[Propriospinal myoclonus induced by relaxation and drowsiness].
Topics: Anticonvulsants; Baclofen; Clonazepam; Electrophysiology; Female; Humans; Middle Aged; Muscle Relaxa | 1998 |
Spinal myoclonus.
Topics: Clonazepam; Female; Humans; Male; Middle Aged; Myoclonus; Spinal Cord Diseases; Tetrabenazine | 1977 |
[Spinal myoclonus synchronized with respiration].
Topics: Aged; Aged, 80 and over; Cervical Vertebrae; Clonazepam; Humans; Male; Myoclonus; Respiration; Spina | 1987 |