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clonazepam and Myelopathy

clonazepam has been researched along with Myelopathy in 8 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Research Excerpts

ExcerptRelevanceReference
"Propriospinal myoclonus arising from a spinal generator may be facilitated by changes in supraspinal control related to vigilance levels."1.30Propriospinal myoclonus upon relaxation and drowsiness: a cause of severe insomnia. ( Liguori, R; Lugaresi, E; Montagna, P; Plazzi, G; Provini, F, 1997)
"Propriospinal myoclonus is a subtype of spinal myoclonus characterized by axial flexion or extension jerks, arrhythmic and prolonged muscle bursts with a pattern of activation consistent with a slow conduction within the propriospinal pathways."1.30[Propriospinal myoclonus induced by relaxation and drowsiness]. ( Arné, P; Dousset, V; Henry, P; Paty, J; Tison, F, 1998)
"Later in the clinical course, the myoclonus became stimulus sensitive and was induced by tendon tap given anywhere on the body, with the latency ranging from 50 to 150 ms irrespective of the sites of tapping."1.29Spinal myoclonus resembling belly dance. ( Araki, K; Kono, I; Nakajima, K; Shibasaki, H; Ueda, Y, 1994)
" The following were taken as evaluation criteria: age, sex, performance status, duration and dosage of previous systemic and current spinal morphine therapy, concomitant analgesic and co-analgesic medication, pretreatment of the dorsal column and neurological dysfunction due to damage either of the nerval plexus or of the medulla spinalis."1.29Complications of spinal opioid therapy: myoclonus, spastic muscle tone and spinal jerking. ( Bingel, U; Kloke, M; Seeber, S, 1994)
"In two, the myoclonus is associated with severe cervical spondylitis."1.26Spinal myoclonus. ( Cherington, M; Hoehn, MM, 1977)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's4 (50.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ray, BK1
Guha, G1
Misra, AK1
Das, SK1
Kryshanovskiĭ, GN1
Grafova, VN1
Danilova, EI1
Kono, I1
Ueda, Y1
Araki, K1
Nakajima, K1
Shibasaki, H1
Kloke, M1
Bingel, U1
Seeber, S1
Montagna, P1
Provini, F1
Plazzi, G1
Liguori, R1
Lugaresi, E1
Tison, F1
Arné, P1
Dousset, V1
Paty, J1
Henry, P1
Hoehn, MM1
Cherington, M1
Kida, Y1
Sawada, T1
Naritomi, H1
Kuriyama, Y1
Ogawa, M1

Other Studies

8 other studies available for clonazepam and Myelopathy

ArticleYear
Involuntary jerking of lower half of the body (spinal myoclonus).
    The Journal of the Association of Physicians of India, 2005, Volume: 53

    Topics: Baclofen; Clonazepam; Clonidine; Diagnosis, Differential; Humans; Lower Extremity; Middle Aged; Myoc

2005
[Effect of benzodiazepines on neuropathologic syndromes of spinal origin].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 97, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Myoclonus; P

1984
Spinal myoclonus resembling belly dance.
    Movement disorders : official journal of the Movement Disorder Society, 1994, Volume: 9, Issue:3

    Topics: Abdominal Muscles; Anterior Horn Cells; Clonazepam; Dancing; Electromyography; Humans; Male; Medulla

1994
Complications of spinal opioid therapy: myoclonus, spastic muscle tone and spinal jerking.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1994, Volume: 2, Issue:4

    Topics: Administration, Oral; Analgesia; Analgesia, Epidural; Baclofen; Clonazepam; Female; Humans; Infusion

1994
Propriospinal myoclonus upon relaxation and drowsiness: a cause of severe insomnia.
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Arachnoid Cysts; Arousal; Clonazepam; Humans; Magnetic Resonance Imagi

1997
[Propriospinal myoclonus induced by relaxation and drowsiness].
    Revue neurologique, 1998, Volume: 154, Issue:5

    Topics: Anticonvulsants; Baclofen; Clonazepam; Electrophysiology; Female; Humans; Middle Aged; Muscle Relaxa

1998
Spinal myoclonus.
    Neurology, 1977, Volume: 27, Issue:10

    Topics: Clonazepam; Female; Humans; Male; Middle Aged; Myoclonus; Spinal Cord Diseases; Tetrabenazine

1977
[Spinal myoclonus synchronized with respiration].
    Rinsho shinkeigaku = Clinical neurology, 1987, Volume: 27, Issue:11

    Topics: Aged; Aged, 80 and over; Cervical Vertebrae; Clonazepam; Humans; Male; Myoclonus; Respiration; Spina

1987