clonazepam has been researched along with Muscle Spasticity in 3 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonazepam was given at low dosage (0." | 2.67 | Treatment of spasticity in children with low dose benzodiazepine. ( Dahlin, M; Knutsson, E; Nergårdh, A, 1993) |
| " The following were taken as evaluation criteria: age, sex, performance status, duration and dosage of previous systemic and current spinal morphine therapy, concomitant analgesic and co-analgesic medication, pretreatment of the dorsal column and neurological dysfunction due to damage either of the nerval plexus or of the medulla spinalis." | 1.29 | Complications of spinal opioid therapy: myoclonus, spastic muscle tone and spinal jerking. ( Bingel, U; Kloke, M; Seeber, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saigal, R | 1 |
| Goyal, L | 1 |
| Yadav, R | 1 |
| Agrawal, A | 1 |
| Mital, P | 1 |
| Patel, B | 1 |
| Kloke, M | 1 |
| Bingel, U | 1 |
| Seeber, S | 1 |
| Dahlin, M | 1 |
| Knutsson, E | 1 |
| Nergårdh, A | 1 |
1 trial available for clonazepam and Muscle Spasticity
| Article | Year |
|---|---|
Treatment of spasticity in children with low dose benzodiazepine.
Topics: Adolescent; Cerebral Palsy; Child; Circadian Rhythm; Clonazepam; Double-Blind Method; Electromyograp | 1993 |
2 other studies available for clonazepam and Muscle Spasticity
| Article | Year |
|---|---|
Stiff Person Syndrome.
Topics: Adult; Antibodies; Anticonvulsants; Autoimmunity; Baclofen; Clonazepam; Electromyography; Glutamate | 2015 |
Complications of spinal opioid therapy: myoclonus, spastic muscle tone and spinal jerking.
Topics: Administration, Oral; Analgesia; Analgesia, Epidural; Baclofen; Clonazepam; Female; Humans; Infusion | 1994 |