clonazepam has been researched along with Muscle Contraction in 15 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There are few reports of SSM related to syringomyelia in the literature." | 1.33 | Segmental spinal myoclonus and syringomyelia: A case report. ( de Coene, B; Gregoire, SM; Hanson, P; Laloux, P; Ossemann, M, 2006) |
| "The data suggest that this rat cardiac arrest model may be a valuable tool for investigating the pathophysiologic mechanisms of posthypoxic myoclonus and for developing new therapeutic strategies for treating the disorder." | 1.29 | Novel rat cardiac arrest model of posthypoxic myoclonus. ( Hussong, MJ; Matsumoto, RR; Schwartz, PH; Truong, DD; Wasterlain, CG, 1994) |
| "Orthostatic tremor, sometimes known as "shaky legs syndrome," is a disorder of middle-aged or elderly people characterized by feelings of unsteadiness in the legs and a fear of falling when standing." | 1.29 | Orthostatic tremor: clinical and electrophysiologic characteristics. ( McManis, PG; Sharbrough, FW, 1993) |
| "PK 11195 which has been shown to inhibit the binding of Ro 5-4864 to cardiac muscle did not antagonize this vasodilatory effect of Ro 5-4864 but increased coronary flow by itself." | 1.27 | Benzodiazepine Ro 5-4864 increases coronary flow. ( French, JF; Grupp, IL; Matlib, MA, 1987) |
| "A patient with post-hypoxic myoclonus, sensitive to therapy with 5-hydroxytryptophan and clonazepam, was subjected to detailed electrophysiological investigation." | 1.26 | Reticular reflex myoclonus: a physiological type of human post-hypoxic myoclonus. ( Adam, J; Chadwick, D; Hallett, M; Marsden, CD, 1977) |
| "Thiopental hypnosis was markedly potentiated after clonazepam." | 1.26 | [Central effects of clonazepam]. ( Furukawa, T; Ono, N, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (26.67) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rankin, JA | 1 |
| Bruton, J | 1 |
| Tavi, P | 1 |
| Aydin, J | 1 |
| Westerblad, H | 1 |
| Lännergren, J | 2 |
| Bruton, JD | 1 |
| Gregoire, SM | 1 |
| Laloux, P | 1 |
| Hanson, P | 1 |
| Ossemann, M | 1 |
| de Coene, B | 1 |
| Sunohara, N | 1 |
| Mukoyama, M | 1 |
| Mano, Y | 1 |
| Satoyoshi, E | 1 |
| Monasterolo, LA | 1 |
| Ochoa, JE | 1 |
| Trumper, L | 1 |
| Elías, MM | 1 |
| Truong, DD | 1 |
| Matsumoto, RR | 1 |
| Schwartz, PH | 1 |
| Hussong, MJ | 1 |
| Wasterlain, CG | 1 |
| McManis, PG | 1 |
| Sharbrough, FW | 1 |
| David, G | 1 |
| Hallett, M | 1 |
| Chadwick, D | 1 |
| Adam, J | 1 |
| Marsden, CD | 2 |
| Ono, N | 1 |
| Furukawa, T | 1 |
| Candenas, ML | 1 |
| Devillier, P | 2 |
| Naline, E | 1 |
| Advenier, C | 2 |
| Blanc, M | 1 |
| Gnassounou, JP | 1 |
| Hughes, AJ | 1 |
| Lees, AJ | 1 |
| Grupp, IL | 1 |
| French, JF | 1 |
| Matlib, MA | 1 |
15 other studies available for clonazepam and Muscle Contraction
| Article | Year |
|---|---|
van Leeuwenhoek's disease.
Topics: Aged; Anticonvulsants; Clonazepam; Diagnosis, Differential; Diaphragm; Dyspnea; Female; Humans; Hype | 2011 |
Mitochondrial and myoplasmic [Ca2+] in single fibres from mouse limb muscles during repeated tetanic contractions.
Topics: Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Clonazepam; Electric Stimulati | 2003 |
Mitochondrial Ca2+ in mouse soleus single muscle fibres in response to repeated tetanic contractions.
Topics: Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Clonazepam; Ionophores; Isomet | 2003 |
Segmental spinal myoclonus and syringomyelia: A case report.
Topics: Abdominal Muscles; Aged; Anticonvulsants; Clonazepam; Electromyography; Female; Humans; Magnetic Res | 2006 |
Action-induced rhythmic dystonia: an autopsy case.
Topics: 5-Hydroxytryptophan; Cerebral Infarction; Clonazepam; Dystonia; Electroencephalography; Electromyogr | 1984 |
Vascular and tubular actions of diazepam in isolated and perfused rat kidney.
Topics: Animals; Benzodiazepinones; Biological Transport, Active; Blood Vessels; Clonazepam; Convulsants; Di | 1995 |
Novel rat cardiac arrest model of posthypoxic myoclonus.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Anticonvulsants; Clonazepam; Disease Models, Ani | 1994 |
Orthostatic tremor: clinical and electrophysiologic characteristics.
Topics: Acceleration; Arm; Clonazepam; Electroencephalography; Electromyography; Electrophysiology; Evoked P | 1993 |
Mitochondrial clearance of cytosolic Ca(2+) in stimulated lizard motor nerve terminals proceeds without progressive elevation of mitochondrial matrix [Ca(2+)].
Topics: Action Potentials; Animals; Antimycin A; Axons; Caffeine; Calcium; Carbachol; Carbonyl Cyanide m-Chl | 1999 |
Reticular reflex myoclonus: a physiological type of human post-hypoxic myoclonus.
Topics: 5-Hydroxytryptophan; Clonazepam; Electroencephalography; Evoked Potentials; Humans; Hypoxia; Male; M | 1977 |
[Central effects of clonazepam].
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzodiazepinones; Central Nervous System; Clonazepam; | 1976 |
Contractile effect of alpha,beta-methylene ATP on the guinea-pig isolated trachea.
Topics: 2-Chloroadenosine; Adenosine Triphosphate; Animals; Benzodiazepinones; Clonazepam; Diazepam; Drug Sy | 1992 |
Peripheral type benzodiazepine receptors and response to adenosine on the guinea-pig isolated trachea.
Topics: Adenosine; Animals; Benzodiazepines; Clonazepam; Diazepam; Dipyridamole; Drug Synergism; GABA-A Rece | 1990 |
Paroxysmal dystonic head tremor.
Topics: Adult; Clonazepam; Dystonia; Humans; Male; Muscle Contraction; Neck Muscles; Torticollis; Tremor | 1991 |
Benzodiazepine Ro 5-4864 increases coronary flow.
Topics: Animals; Benzodiazepinones; Clonazepam; Convulsants; Coronary Circulation; Heart Rate; In Vitro Tech | 1987 |