clonazepam has been researched along with Lewy Body Disease in 8 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Lewy Body Disease: A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with rapid eye movement sleep behavior disorder are frequently prone to sleep-related injuries and should be treated to prevent injury with either melatonin 3-12 mg or clonazepam 0." | 2.55 | REM Sleep Behavior Disorder in Parkinson's Disease and Other Synucleinopathies. ( Boeve, AR; Boeve, BF; St Louis, EK, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Morioka, D | 1 |
| Kobayashi, R | 1 |
| Hayashi, H | 1 |
| Kawakatsu, S | 1 |
| Suzuki, A | 1 |
| St Louis, EK | 1 |
| Boeve, AR | 1 |
| Boeve, BF | 1 |
| Hershey, LA | 1 |
| Coleman-Jackson, R | 1 |
| Fujishiro, H | 1 |
| Kimura, H | 1 |
| Nakamura, T | 1 |
| Torii, Y | 1 |
| Iritani, S | 1 |
| Ozaki, N | 1 |
| Coelho, FM | 1 |
| Kim, LJ | 1 |
| Cremaschi, RC | 1 |
| Pereira, DD | 1 |
| Tufik, S | 1 |
| Fernández-Arcos, A | 1 |
| Iranzo, A | 1 |
| Serradell, M | 1 |
| Gaig, C | 1 |
| Santamaria, J | 1 |
| Cersosimo, MG | 1 |
| Koller, WC | 1 |
| Massironi, G | 1 |
| Galluzzi, S | 1 |
| Frisoni, GB | 1 |
2 reviews available for clonazepam and Lewy Body Disease
| Article | Year |
|---|---|
REM Sleep Behavior Disorder in Parkinson's Disease and Other Synucleinopathies.
Topics: Central Nervous System Depressants; Clonazepam; GABA Modulators; Humans; Lewy Body Disease; Melatoni | 2017 |
Pharmacological Management of Dementia with Lewy Bodies.
Topics: Age Factors; Aged; Anticonvulsants; Antiparkinson Agents; Cholinesterase Inhibitors; Clinical Trials | 2019 |
6 other studies available for clonazepam and Lewy Body Disease
| Article | Year |
|---|---|
Clonazepam-induced misidentification in prodromal dementia with Lewy bodies.
Topics: Clonazepam; Humans; Lewy Bodies; Lewy Body Disease; Prodromal Symptoms | 2022 |
Hypochondriasis in the elderly and Lewy body disease.
Topics: Aged; Clonazepam; Humans; Hyperacusis; Hypochondriasis; Indenes; Lewy Body Disease; Magnetic Resonan | 2019 |
Continuous positive airway pressure treatment associated with face injury during rapid eye movement behavior disorder.
Topics: Aged, 80 and over; Clonazepam; Continuous Positive Airway Pressure; Facial Injuries; Female; Humans; | 2015 |
The Clinical Phenotype of Idiopathic Rapid Eye Movement Sleep Behavior Disorder at Presentation: A Study in 203 Consecutive Patients.
Topics: Aged; Aged, 80 and over; Clonazepam; Continuous Positive Airway Pressure; Dementia; Electromyography | 2016 |
Movement disorders.
Topics: Adult; Aged; Anticonvulsants; Atrophy; Brain; Child; Clonazepam; Diagnosis, Differential; Female; Hu | 2003 |
Drug treatment of REM sleep behavior disorders in dementia with Lewy bodies.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Benzodiazepines; Cholinesterase Inhibitors; Clonazepam; Do | 2003 |