clonazepam has been researched along with Hyperekplexia in 3 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Hyperekplexia: A neurological disorder characterized by an excessive startle reaction with ABNORMAL REFLEX; MYOCLONIC JERKS; and MUSCLE HYPERTONIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral clonazepam is an effective therapy besides behavioral and safety interventions for hereditary cases." | 2.66 | Hyperekplexia and other startle syndromes. ( Pandey, S; Saini, AG, 2020) |
| "Hyperekplexia is an exaggerated startle to external stimuli associated with a generalised increase in tone seen in neonates with both sporadic and genetic predisposition." | 1.56 | Abnormal neurodevelopment outcome in case of neonatal hyperekplexia secondary to missense mutation in ( Chopra, S; Choudhury, V; Gupta, NP; Verma, V, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hakeem, H | 1 |
| Khurshid, R | 1 |
| Siddiqui, F | 1 |
| Bhatti, DE | 1 |
| Saini, AG | 1 |
| Pandey, S | 1 |
| Gupta, NP | 1 |
| Verma, V | 1 |
| Chopra, S | 1 |
| Choudhury, V | 1 |
1 review available for clonazepam and Hyperekplexia
| Article | Year |
|---|---|
Hyperekplexia and other startle syndromes.
Topics: Adult; Child; Clonazepam; Humans; Hyperekplexia; Infant; Infant, Newborn; Muscle Rigidity; Receptors | 2020 |
2 other studies available for clonazepam and Hyperekplexia
| Article | Year |
|---|---|
Approach to exaggerated startle reflex: a case of hyperekplexia minor.
Topics: Adult; Anticonvulsants; Central Nervous System Diseases; Clonazepam; Humans; Hyperekplexia; Male; Re | 2020 |
Abnormal neurodevelopment outcome in case of neonatal hyperekplexia secondary to missense mutation in
Topics: Anticonvulsants; Child, Preschool; Clonazepam; Diagnosis, Differential; Diagnostic Errors; Humans; H | 2020 |