clonazepam has been researched along with Hematologic Malignancies in 1 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacokinetic (PK) data were compared with those previously collected in patients (n=127) treated with phenytoin for seizure prophylaxis." | 2.75 | Influence on Busilvex pharmacokinetics of clonazepam compared to previous phenytoin historical data. ( Bacigalupo, A; Buzyn, A; Cahn, JY; Carreras, E; Kröger, N; Puozzo, C; Sanz, G; Vernant, JP, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carreras, E | 1 |
| Cahn, JY | 1 |
| Puozzo, C | 1 |
| Kröger, N | 1 |
| Sanz, G | 1 |
| Buzyn, A | 1 |
| Bacigalupo, A | 1 |
| Vernant, JP | 1 |
1 trial available for clonazepam and Hematologic Malignancies
| Article | Year |
|---|---|
Influence on Busilvex pharmacokinetics of clonazepam compared to previous phenytoin historical data.
Topics: Adolescent; Adult; Alkylating Agents; Anticonvulsants; Busulfan; Clonazepam; Cyclophosphamide; Drug | 2010 |