clonazepam has been researched along with Heart Failure in 3 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 78-year-old man with a history of congestive heart failure and coronary artery disease began taking amiodarone to suppress sustained ventricular tachycardia." | 3.68 | Amiodarone-clonazepam interaction. ( Ellsworth, AJ; Leversee, JH; Witt, DM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dietl, A | 1 |
| Maack, C | 1 |
| Liu, T | 1 |
| Takimoto, E | 1 |
| Dimaano, VL | 1 |
| DeMazumder, D | 1 |
| Kettlewell, S | 1 |
| Smith, G | 1 |
| Sidor, A | 1 |
| Abraham, TP | 1 |
| O'Rourke, B | 1 |
| Witt, DM | 1 |
| Ellsworth, AJ | 1 |
| Leversee, JH | 1 |
1 review available for clonazepam and Heart Failure
| Article | Year |
|---|---|
Targeting Mitochondrial Calcium Handling and Reactive Oxygen Species in Heart Failure.
Topics: Antioxidants; Benzhydryl Compounds; Calcium; Clonazepam; Glucosides; Heart Failure; Humans; Mitochon | 2017 |
2 other studies available for clonazepam and Heart Failure
| Article | Year |
|---|---|
Inhibiting mitochondrial Na+/Ca2+ exchange prevents sudden death in a Guinea pig model of heart failure.
Topics: Animals; Anti-Arrhythmia Agents; Calcium; Cardiomegaly; Clonazepam; Death, Sudden, Cardiac; Disease | 2014 |
Amiodarone-clonazepam interaction.
Topics: Aged; Amiodarone; Clonazepam; Drug Interactions; Heart Failure; Humans; Male; Tachycardia, Ventricul | 1993 |