clonazepam has been researched along with Epileptiform Neuralgia in 13 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonazepam seems to be an effective drug in idiopathic trigeminal neuralgia." | 9.04 | Clonazepam in facial neuralgia and cluster headache. Clinical and electrophysiological study. ( Caccia, MR, 1975) |
| "A study of 21 patients has shown that clonazepam is an effective drug in preventing attacks of pain in trigeminal neuralgia and Sluder's syndrome." | 7.65 | Clonazepam in cranial neuralgias. ( Scarlato, G; Smirne, S, 1977) |
| " For treating trigeminal neuralgia, carbamazepine had a combined number needed to treat of 2." | 6.17 | Anticonvulsant drugs for management of pain: a systematic review. ( Carroll, D; Jadad, AR; McQuay, H; Moore, A; Wiffen, P, 1995) |
| "Clonazepam seems to be an effective drug in idiopathic trigeminal neuralgia." | 5.04 | Clonazepam in facial neuralgia and cluster headache. Clinical and electrophysiological study. ( Caccia, MR, 1975) |
| "A study of 21 patients has shown that clonazepam is an effective drug in preventing attacks of pain in trigeminal neuralgia and Sluder's syndrome." | 3.65 | Clonazepam in cranial neuralgias. ( Scarlato, G; Smirne, S, 1977) |
| "Results are reported of a preliminary trial with clonazepam in 19 patients with trigeminal neuralgia refractory to carbamazepine treatment." | 3.65 | The use of clonazepam in the treatment of tic douloureux (a preliminary report). ( Chandra, B, 1976) |
| " On the basis of these considerations and clinical reports describing the use of these drugs, we make dosage recommendations to enable the practitioner to individualize therapeutic regimens." | 2.38 | Drugs used in the management of trigeminal neuralgia. ( Patsalos, PN; Zakrzewska, JM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brid, T | 1 |
| Sacristán de Lama, MP | 1 |
| González, N | 1 |
| Baamonde, A | 1 |
| Martin, WJ | 1 |
| Forouzanfar, T | 1 |
| Jacob, M | 1 |
| Vighetto, A | 1 |
| Bernard, M | 1 |
| Tilikete, C | 1 |
| Karlov, VA | 1 |
| Savitskaia, ON | 1 |
| Sweeney, PJ | 1 |
| McQuay, H | 1 |
| Carroll, D | 1 |
| Jadad, AR | 1 |
| Wiffen, P | 1 |
| Moore, A | 1 |
| Smirne, S | 1 |
| Scarlato, G | 1 |
| Court, JE | 1 |
| Kase, CS | 1 |
| Chandra, B | 1 |
| Caccia, MR | 1 |
| Zakrzewska, JM | 1 |
| Patsalos, PN | 1 |
| Green, MW | 1 |
| de Negrotto, OV | 1 |
| Dalmás, JF | 1 |
| Negrotto, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Erenumab as a Therapeutic Approach for the Management of Trigeminal Neuropathic Pain (TNP)[NCT05142228] | Phase 2 | 5 participants (Actual) | Interventional | 2022-04-01 | Terminated (stopped due to Low enrollment rate) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for clonazepam and Epileptiform Neuralgia
| Article | Year |
|---|---|
The efficacy of anticonvulsants on orofacial pain: a systematic review.
Topics: Amines; Anticonvulsants; Burning Mouth Syndrome; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Ac | 2011 |
Anticonvulsant drugs for management of pain: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diabetic Neuropathies; Humans; Pain; Phenytoin; Treatmen | 1995 |
Drugs used in the management of trigeminal neuralgia.
Topics: Anticonvulsants; Baclofen; Carbamazepine; Clonazepam; Humans; Oxcarbazepine; Phenytoin; Trigeminal N | 1992 |
2 trials available for clonazepam and Epileptiform Neuralgia
| Article | Year |
|---|---|
Anticonvulsant drugs for management of pain: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diabetic Neuropathies; Humans; Pain; Phenytoin; Treatmen | 1995 |
Clonazepam in facial neuralgia and cluster headache. Clinical and electrophysiological study.
Topics: Adult; Aged; Benzodiazepinones; Clinical Trials as Topic; Clonazepam; Female; Headache; Humans; Male | 1975 |
9 other studies available for clonazepam and Epileptiform Neuralgia
| Article | Year |
|---|---|
Topical Gabapentin as Add-on Therapy for Trigeminal Neuralgia. A Case Report.
Topics: Acetaminophen; Administration, Topical; Aged, 80 and over; Analgesics; Carbamazepine; Clonazepam; Dr | 2017 |
Ocular neuromyotonia secondary to a cavernous sinus meningioma.
Topics: Acetazolamide; Adult; Carbamazepine; Cavernous Sinus; Clonazepam; Diplopia; Esotropia; Female; Human | 2006 |
[Comparative effectiveness of antiepileptic preparations in the treatment of patients with trigeminal neuralgia].
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Follow-Up Studies; Humans; Morpholines; Py | 1980 |
Tic douloureux.
Topics: Carbamazepine; Chlorphenesin; Clonazepam; Female; Humans; Male; Phenytoin; Trigeminal Nerve; Trigemi | 1981 |
Clonazepam in cranial neuralgias.
Topics: Adult; Aged; Benzodiazepinones; Clonazepam; Cranial Nerves; Facial Neuralgia; Female; Humans; Male; | 1977 |
Treatment of tic douloureux with a new anticonvulsant (clonazepam).
Topics: Adult; Aged; Benzodiazepinones; Clonazepam; Disorders of Excessive Somnolence; Female; Humans; Male; | 1976 |
The use of clonazepam in the treatment of tic douloureux (a preliminary report).
Topics: Aged; Benzodiazepinones; Clonazepam; Electroencephalography; Female; Humans; Male; Middle Aged; Trig | 1976 |
Medical treatment of trigeminal neuralgia and cluster headache.
Topics: Benzodiazepinones; Clonazepam; Cluster Headache; Humans; Trigeminal Neuralgia; Vascular Headaches | 1985 |
[Trigeminal neuralgia. Treatment with clonazepam].
Topics: Adult; Aged; Benzodiazepinones; Clonazepam; Drug Evaluation; Female; Humans; Male; Middle Aged; Trig | 1974 |