clonazepam has been researched along with Epilepsy in 220 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
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"We included RCTs or quasi-RCTs comparing oral clonazepam used as monotherapy treatment versus placebo or a different anti-seizure medication (active comparator) in people of any age with newly diagnosed epilepsy, defined according to the clinical practical definition proposed by the International League Against Epilepsy (ILAE)." | 9.22 | Clonazepam monotherapy for treating people with newly diagnosed epilepsy. ( Bragazzi, NL; Brigo, F; Igwe, SC; Lattanzi, S, 2022) |
"To evaluate the effect of low-dose clonazepam (CZP) on the amount of epileptiform activity in children with focal and generalized epilepsy." | 9.09 | Reduction of epileptiform activity in response to low-dose clonazepam in children with epilepsy: a randomized double-blind study. ( Amark, P; Dahlin, M; Knutsson, E; Nergårdh, A, 2000) |
"Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial." | 9.04 | Treatment of epilepsy with clonazepam and its effect on other anticonvulsants. ( Johnson, RH; Keogh, HJ; Lambie, DG; Melville, ID; Nanda, RN, 1977) |
"To assess the efficacy and tolerability of oral clonazepam used as monotherapy for newly diagnosed epilepsy, when compared with placebo or a different anti-seizure medication." | 9.01 | Clonazepam monotherapy for treating people with newly diagnosed epilepsy. ( Bragazzi, NL; Brigo, F; Igwe, SC; Lattanzi, S, 2019) |
"To compare patient characteristics and treatment patterns among clobazam (CLB) and clonazepam (CZP)-treated patients with epilepsy in a longitudinal primary care database." | 7.83 | Clobazam and clonazepam use in epilepsy: Results from a UK database incident user cohort study. ( Brodie, MJ; Chung, S; François, C; Guiraud-Diawara, A; Isojarvi, J; Quelen, C; Shen, V; Verpillat, P; Wade, A, 2016) |
"Although it has been reported that some antiepileptic drugs have inducing or inhibiting effects on lamotrigine (LTG) clearance, whether they have the same effects in Asian epilepsy patients as in those in other countries has not been clarified, especially in children." | 7.83 | The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy. ( Abe, S; Azuma, Y; Ishihara, N; Ito, Y; Itomi, K; Kidokoro, H; Kojima, S; Kurahashi, H; Kurahashi, N; Maruyama, K; Natsume, J; Negoro, T; Okumura, A; Suzuki, M; Takeuchi, T; Tsuji, T; Watanabe, K; Yamada, K; Yamamoto, H, 2016) |
"In treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens, and to enhance quality of life for patients and their families." | 7.80 | Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. ( Chung, S; Kuzniecky, R; Perry, MS; Sankar, R; Sinha, S, 2014) |
" The combination of AGLD (5 mg/kg) with phenobarbital (PB, applied at its subeffective dose of 15 mg/kg) significantly shortened motor seizure and afterdischarge duration in amygdala-kindled seizures." | 7.73 | Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats. ( Borowicz, KK; Czuczwar, SJ, 2005) |
"To report 3 cases with focal lesional epilepsy that had non-convulsive status epilepticus (NCSE) induced by treatment with tiagabine (TGB) and review the previously published cases." | 7.73 | Tiagabine-induced generalised non convulsive status epilepticus in patients with lesional focal epilepsy. ( Cowley, M; Kilpatrick, C; Kornberg, AJ; Matkovic, Z; O'Brien, TJ; Vinton, A, 2005) |
"We report the effects of withdrawal of clonazepam (CZP) at a rate of 1 mg/week in 23 patients with chronic active epilepsy." | 7.68 | Discontinuation of clonazepam in patients with active epilepsy. ( Chataway, J; Duncan, JS; Fowler, A; Thompson, PJ, 1993) |
"Sixty patients (age-range one month to 14 years) with other types of epilepsy than infantile spasms were treated with clonazepam." | 7.67 | Clonazepam monotherapy for epilepsy in childhood. ( Ishikawa, A; Kajii, N; Kohsaka, S; Nagashima, T; Sakuma, N, 1985) |
"Of 88 patients with intractable epilepsy, 60 have been treated with clonazepam for up to three years and 60 have been treated with sodium valproate for up to 18 months." | 7.65 | Sodium valproate and clonazepam in the treatment of intractable epilepsy. ( Anthony, M; Lance, JW, 1977) |
"Clonazepam was administered to 4 patients with an unusual form of photosensitive epilepsy." | 7.65 | Clinical and EEG response to clonazepam in four patients with self-induced photosensitive epilepsy. ( Ames, FR; Enderstein, O, 1976) |
" The peak concentration (Cmax) of CZP and the time intervals from dosing to Cmax (Tmax) were 20." | 6.70 | Pharmacokinetic and pharmacodynamic effects of clonazepam in children with epilepsy treated with valproate: a preliminary study. ( Wang, L; Wang, XD, 2002) |
" The median elimination half-life (t1/2) in patients receiving concomitant valproate (VPA) was 43." | 6.68 | Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy. ( Boreus, L; Eriksson, AS; Hoppu, K; Nergårdh, A, 1996) |
""Old" cases of epilepsy are significantly more resistant to clonazepam medication." | 6.65 | Clonazepam in the treatment of drug-resistant epilepsy: a clinical short and long term follow-up study. ( Bacia, T; Okuszko, S; Purska-Rowińska, E, 1980) |
", in proposing a safe CZP withdrawal rate of 0." | 5.29 | Clonazepam withdrawal in 13 patients with active epilepsy and drug side effects. ( Buchanan, N; Sharpe, C, 1994) |
"Clonazepam was administered both intramuscularly (i." | 5.28 | [The effect of clonazepam on experimental epilepsy induced by electrostimulation]. ( Bozić, K; Filipović, D; Grujić, N; Ivetić, V; Nikolić, V, 1992) |
"Primary reading epilepsy is a rare form of reflex epilepsy, in which reading is the specific stimulus evoking attacks." | 5.28 | [Primary reading epilepsy: therapeutic efficacy of clonazepam in one case]. ( Castro, LH; Grossmann, RM; Marques-Assis, L; Yacubian, EM, 1990) |
"Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment." | 5.27 | Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983) |
"Clonazepam (Antelepsin) was tested on 179 patients in 8 institutions during a period of 180 days." | 5.26 | [Treatment of epilepsy with clonazepam (Antelepsin)]. ( Arndt, R; Böhl, I; Brückner, HJ; Cammann, G; Du Chesne, HJ; Fischer, W; Hobusch, D; Knaape, HH; Müller, D; Oettinger, B; Rabending, G; Rohmann, E; Rössger, B; Schmidtsdorf, R; Vesper, J; Zettler, H, 1979) |
"We included RCTs or quasi-RCTs comparing oral clonazepam used as monotherapy treatment versus placebo or a different anti-seizure medication (active comparator) in people of any age with newly diagnosed epilepsy, defined according to the clinical practical definition proposed by the International League Against Epilepsy (ILAE)." | 5.22 | Clonazepam monotherapy for treating people with newly diagnosed epilepsy. ( Bragazzi, NL; Brigo, F; Igwe, SC; Lattanzi, S, 2022) |
"To evaluate the effect of low-dose clonazepam (CZP) on the amount of epileptiform activity in children with focal and generalized epilepsy." | 5.09 | Reduction of epileptiform activity in response to low-dose clonazepam in children with epilepsy: a randomized double-blind study. ( Amark, P; Dahlin, M; Knutsson, E; Nergårdh, A, 2000) |
"Plasma clonazepam (CZP) and its metabolite [7-aminoclonazepam (7ACZP) and 7-acetamidoclonazepam (7AACZP)] concentrations were measured during a single dosing interval in 10 pediatric epilepsy patients (2-18 years, 11-102 kg) who had been receiving CZP therapeutically from 2 weeks to 4 years." | 5.08 | Clonazepam disposition in pediatric patients. ( Edge, JH; Walson, PD, 1996) |
"The drug encorat, an analogue of valproic acid (Sun, India) was given to 16 children aged from 4 month to 5 years suffering from resistant forms of early infantile epilepsy." | 5.07 | [The enkorat treatment of infantile spasms and the Lennox-Gastaut syndrome]. ( Badalian, LO; Iskander, MB; Kharlamov, DA; Medvedev, MI; Mukhin, KIu; Temin, PA; Veselov, NK, 1994) |
"Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial." | 5.04 | Treatment of epilepsy with clonazepam and its effect on other anticonvulsants. ( Johnson, RH; Keogh, HJ; Lambie, DG; Melville, ID; Nanda, RN, 1977) |
"To assess the efficacy and tolerability of oral clonazepam used as monotherapy for newly diagnosed epilepsy, when compared with placebo or a different anti-seizure medication." | 5.01 | Clonazepam monotherapy for treating people with newly diagnosed epilepsy. ( Bragazzi, NL; Brigo, F; Igwe, SC; Lattanzi, S, 2019) |
" Clonazepam, chlorazepate, nitrazepam and clobazam are also prescribed as chronic treatment of various forms of epilepsy." | 4.76 | [Benzodiazepines in the treatment of epilepsy]. ( Loiseau, P, 1983) |
"1%) received an anti-epileptic medication during pregnancy of which more than half received lamotrigine or levetiracetam." | 4.12 | Use of antiepileptic drugs by trimester. ( Benson, RJ; D'Alton, ME; Friedman, AM; Huang, Y; Logue, TC; Pack, AM; Wright, JD, 2022) |
" According to our experience, the dual therapy with Carbamazepine and Clonazepam has led to a good control of seizures." | 4.12 | Expanding the genetic and clinical characteristics of Protocadherin 19 gene mutations. ( Dell'Isola, GB; Di Cara, G; Fattorusso, A; Imperatore, V; Mencaroni, E; Prontera, P; Striano, P; Tascini, G; Verrotti, A, 2022) |
"Female sex, refractoriness, and clonazepam use may be risk factors for depression after epilepsy diagnosis." | 3.96 | Factors associated with depression in people with epilepsy: a retrospective case-control analysis. ( Chang, RSK; Ho, PH; Leung, IYH; Leung, WCY, 2020) |
"A 24-year-old woman with a long-standing history of polio and a 2-year history of epilepsy developed a serious ADR after repeated exposure to oral clonazepam combined with sodium valproate that manifested as myotoxicity and elevated levels of creatine phosphokinase." | 3.91 | A serious adverse drug reaction probably induced by clonazepam: a case report of myotoxicity. ( Han, X; Wang, J, 2019) |
"To compare patient characteristics and treatment patterns among clobazam (CLB) and clonazepam (CZP)-treated patients with epilepsy in a longitudinal primary care database." | 3.83 | Clobazam and clonazepam use in epilepsy: Results from a UK database incident user cohort study. ( Brodie, MJ; Chung, S; François, C; Guiraud-Diawara, A; Isojarvi, J; Quelen, C; Shen, V; Verpillat, P; Wade, A, 2016) |
"Although it has been reported that some antiepileptic drugs have inducing or inhibiting effects on lamotrigine (LTG) clearance, whether they have the same effects in Asian epilepsy patients as in those in other countries has not been clarified, especially in children." | 3.83 | The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy. ( Abe, S; Azuma, Y; Ishihara, N; Ito, Y; Itomi, K; Kidokoro, H; Kojima, S; Kurahashi, H; Kurahashi, N; Maruyama, K; Natsume, J; Negoro, T; Okumura, A; Suzuki, M; Takeuchi, T; Tsuji, T; Watanabe, K; Yamada, K; Yamamoto, H, 2016) |
"This case suggests that rufinamide may induce the potentially serious adverse effect of agranulocytosis." | 3.81 | A granulocytosis associated with rufinamide: A case report. ( Awaya, T; Heike, T; Ide, M; Kato, T; Nakata, M; Saito, K; Yoshida, T, 2015) |
"In treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens, and to enhance quality of life for patients and their families." | 3.80 | Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. ( Chung, S; Kuzniecky, R; Perry, MS; Sankar, R; Sinha, S, 2014) |
"A 54-year-old woman with known epilepsy developed convulsions after using rifampicin and flucloxacillin, despite the use of maintenance treatment in the form of carbamazepine, valproic acid and clonazepam." | 3.80 | [Convulsions due to an interaction between anti-epileptic drugs and rifampicin]. ( Hanrath, MA; Swart, EL, 2014) |
" In this study the anticonvulsant actions of norfluoxetine and fluoxetine were studied and compared to those of phenytoin and clonazepam in pentylenetetrazol-induced mouse epilepsy models." | 3.73 | Norfluoxetine and fluoxetine have similar anticonvulsant and Ca2+ channel blocking potencies. ( Harasztosi, C; Kecskeméti, V; Nánási, PP; Pál, B; Riba, P; Rusznák, Z; Szûcs, G; Wagner, R, 2005) |
" The combination of AGLD (5 mg/kg) with phenobarbital (PB, applied at its subeffective dose of 15 mg/kg) significantly shortened motor seizure and afterdischarge duration in amygdala-kindled seizures." | 3.73 | Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats. ( Borowicz, KK; Czuczwar, SJ, 2005) |
"During her first pregnancy, a 37-year-old woman with idiopathic generalised epilepsy that was adequately controlled with lamotrigine experienced a series of epileptic seizures following an elective caesarean section." | 3.73 | [Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy]. ( Bloem, BR; Renier, WO; Voermans, NC; Zwarts, MJ, 2005) |
"To report 3 cases with focal lesional epilepsy that had non-convulsive status epilepticus (NCSE) induced by treatment with tiagabine (TGB) and review the previously published cases." | 3.73 | Tiagabine-induced generalised non convulsive status epilepticus in patients with lesional focal epilepsy. ( Cowley, M; Kilpatrick, C; Kornberg, AJ; Matkovic, Z; O'Brien, TJ; Vinton, A, 2005) |
" The mother had taken clonazepam, a benzodiazepine, and carbamazepine during the entire pregnancy for epilepsy." | 3.69 | Paralytic ileus in a fetus-neonate after maternal intake of benzodiazepine. ( Haeusler, MC; Hoellwarth, ME; Holzer, P, 1995) |
"The development of tolerance to the anticonvulsant effects of clonazepam, clobazam, and diazepam were studied in genetically epilepsy-prone rats following intraperitoneal (IP) or oral administration." | 3.69 | Tolerance to anticonvulsant effects of some benzodiazepines in genetically epilepsy prone rats. ( Aguglia, U; de Sarro, A; De Sarro, G; Di Paola, ED, 1996) |
"The purpose of our study was to evaluate the hypothesis that much of the reported variability in the range of concentrations of plasma clonazepam (and also in the range of concentrations of its major metabolite, 7-aminoclonazepam) encountered in pediatric epilepsy patients is due to collection of samples at random times after dosing." | 3.68 | Clonazepam and 7-aminoclonazepam in human plasma. ( Edge, JH; Rane, A; Walson, PD, 1991) |
"We report the effects of withdrawal of clonazepam (CZP) at a rate of 1 mg/week in 23 patients with chronic active epilepsy." | 3.68 | Discontinuation of clonazepam in patients with active epilepsy. ( Chataway, J; Duncan, JS; Fowler, A; Thompson, PJ, 1993) |
"Sixty patients (age-range one month to 14 years) with other types of epilepsy than infantile spasms were treated with clonazepam." | 3.67 | Clonazepam monotherapy for epilepsy in childhood. ( Ishikawa, A; Kajii, N; Kohsaka, S; Nagashima, T; Sakuma, N, 1985) |
"The therapeutics results with the use of different drugs (diazepam, nitrazepam, clonazepam, diphenylhydantoin, barbiturates--phenobarbital and primidone--, sodium dipropylacetate and ACTH) in twenty-nine patients with Lennox--Gastaut syndrome are carefully analysed." | 3.65 | [Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome]. ( Lison, MP; Speciali, GG, 1977) |
"Of 88 patients with intractable epilepsy, 60 have been treated with clonazepam for up to three years and 60 have been treated with sodium valproate for up to 18 months." | 3.65 | Sodium valproate and clonazepam in the treatment of intractable epilepsy. ( Anthony, M; Lance, JW, 1977) |
"The influence of clonazepam on steady-state serum levels of diphenylhydantoin, phenobarbital and carbamazepine was studied in 22 patients with epilepsy receiving one or two of these drugs." | 3.65 | Lack of effect of clonazepam on serum levels of diphenylhydantoin, phenobarbital and carbamazepine. ( Johannessen, SI; Munthe-Kaas, AW; Strandjord, RE, 1977) |
"Clonazepam, an antiepileptic benzodiazepine derivative was administered into 30 patients mainly with incurable type epilepsy." | 3.65 | [Antiepileptic activity of clonazepam--an antiepileptic benzodiazepine derivative]. ( Iwata, T; Kato, H; Mori, T; Moriuchi, I; Yoshimura, T, 1976) |
"Clonazepam was administered to 4 patients with an unusual form of photosensitive epilepsy." | 3.65 | Clinical and EEG response to clonazepam in four patients with self-induced photosensitive epilepsy. ( Ames, FR; Enderstein, O, 1976) |
" The peak concentration (Cmax) of CZP and the time intervals from dosing to Cmax (Tmax) were 20." | 2.70 | Pharmacokinetic and pharmacodynamic effects of clonazepam in children with epilepsy treated with valproate: a preliminary study. ( Wang, L; Wang, XD, 2002) |
" The median elimination half-life (t1/2) in patients receiving concomitant valproate (VPA) was 43." | 2.68 | Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy. ( Boreus, L; Eriksson, AS; Hoppu, K; Nergårdh, A, 1996) |
""Old" cases of epilepsy are significantly more resistant to clonazepam medication." | 2.65 | Clonazepam in the treatment of drug-resistant epilepsy: a clinical short and long term follow-up study. ( Bacia, T; Okuszko, S; Purska-Rowińska, E, 1980) |
" However, their chronic use may be associated with serious sedative-hypnotic effects that interfere with cognitive function and behavior." | 2.37 | Use of barbiturates and benzodiazepines in treatment of epilepsy. ( Vining, EP, 1986) |
" New antiepileptic drugs have improved medical management, and technical and theoretical advances in pharmacokinetics have permitted physicians to design balanced dosing for individual patients." | 2.36 | Recent developments in the diagnosis and therapy of epilepsy. ( Crandall, PH; Engel, J; Sterman, MB; Troupin, AS; Wasterlain, CG, 1982) |
"A diagnosed of congenital microcephaly was made." | 1.56 | Congenital microcephaly with early onset epileptic encephalopathy caused by ASNS gene mutation: A case report. ( Chen, C; Hao, Y; Liang, J; Liu, X, 2020) |
"Epilepsy is very difficult to treat and often involves the combination of two or more AEDs." | 1.56 | Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database. ( Hayashi, T; Noguchi, Y; Tachi, T; Takaoka, M; Teramachi, H, 2020) |
"To study the risk of intellectual disability and delayed development in childhood milestones among children of women who used valproate or other AEDs during pregnancy." | 1.56 | Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones. ( Christensen, J; Daugaard, CA; Dreier, JW; Pedersen, L; Sun, Y, 2020) |
" Subsequently, the dosage was doubled (1mg twice daily), and complete cessation of seizures was achieved 20 days later." | 1.46 | Early onset epileptic encephalopathy with a novel GABRB3 mutation treated effectively with clonazepam: A case report. ( Lian, Y; Xie, N; Zhang, Y, 2017) |
"In patients with high-grade glioma seizures occur relatively frequently during the end-of-life phase." | 1.40 | [Gliomas: fighting until the end against epilepsy; administration of antiepileptic drugs in the end-of-life phase]. ( Boddaert, MS; Koekkoek, JA; Taphoorn, M, 2014) |
"The four classic categories of paroxysmal dyskinesias are kinesigenic, nonkinesigenic, exercise-induced and hypnogenic." | 1.40 | A rare paroxysmal movement disorder: mixed type of paroxysmal dyskinesia. ( Arpaci, B; Atakli, D; Guresci, B; Sen, A, 2014) |
"Clonazepam wafers are an effective acute therapy for prolonged seizures." | 1.36 | Dissolving oral clonazepam wafers in the acute treatment of prolonged seizures. ( Hastriter, EV; Ng, YT; Troester, MM, 2010) |
"Two central sleep apneas with deep desaturation followed by generalized tonic-clonic seizures were documented." | 1.36 | Late-onset nocturnal intractable seizure during sleep: what is the origin? ( Liesiene, V; Miliauskas, S; Sakalauskas, R; Zemaitis, M, 2010) |
"Epilepsy is associated with the presence of cataract." | 1.36 | Prevalence of Epilepsy among Cataract Patients. ( Hanhart, J; Kaiserman, I; Levartovsky, S; Nemet, A; Vinker, S, 2010) |
"Epilepsy was most common among those with maternal deletions and unknown subtypes, with catastrophic epilepsies present in only these two subtypes." | 1.35 | Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options. ( Braun, EK; Bruno, P; Conant, KD; Nespeca, MP; Said, RR; Thibert, RL; Thiele, EA, 2009) |
" Limbic (psychomotor) seizure activity was evoked in albino Swiss mice by a current (32 mA, 6 Hz, 3s stimulus duration) delivered via ocular electrodes and isobolographic analysis for parallel and non-parallel dose-response effects was used to characterize the consequent anticonvulsant interactions between the various drug combinations." | 1.35 | Isobolographic characterization of interactions of levetiracetam with the various antiepileptic drugs in the mouse 6 Hz psychomotor seizure model. ( Luszczki, JJ; Patsalos, PN; Wlaz, A; Wojda, E, 2009) |
"Reported is the association of REM behavior disorder (RBD) with late-onset, sleep-related, tonic-clonic seizures in two elderly men." | 1.33 | REM behavior disorder associated with epileptic seizures. ( Manni, R; Terzaghi, M, 2005) |
"Carbamazepine (CBZ) was used in seven patients at the onset of AS." | 1.32 | Absence seizures in patients with localization-related epilepsy. ( Hayakawa, F; Nakai, Y; Negoro, T; Okumura, A; Sofue, A; Toyota, N; Watanabe, K, 2003) |
"Clonazepam has recently been found by us to selectively diminish RD in BCECT." | 1.30 | Rhythmic slow activity in benign childhood epilepsy with centrotemporal spikes. ( Mitsudome, A; Ogawa, A; Ohu, M; Yasumoto, S, 1997) |
"Clonazepam was the most effective antiepileptic drug, and it also normalized the EEG when started in childhood or at the onset of puberty." | 1.30 | Neurophysiological findings in the northern epilepsy syndrome. ( Hirvasniemi, A; Lang, AH; Siivola, J, 1997) |
"One also had features of infantile autism." | 1.29 | Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs. ( Chesler, N; Christianson, AL; Kromberg, JG, 1994) |
", in proposing a safe CZP withdrawal rate of 0." | 1.29 | Clonazepam withdrawal in 13 patients with active epilepsy and drug side effects. ( Buchanan, N; Sharpe, C, 1994) |
"Primary reading epilepsy is a rare form of reflex epilepsy, in which reading is the specific stimulus evoking attacks." | 1.28 | [Primary reading epilepsy: therapeutic efficacy of clonazepam in one case]. ( Castro, LH; Grossmann, RM; Marques-Assis, L; Yacubian, EM, 1990) |
"Clonazepam was administered both intramuscularly (i." | 1.28 | [The effect of clonazepam on experimental epilepsy induced by electrostimulation]. ( Bozić, K; Filipović, D; Grujić, N; Ivetić, V; Nikolić, V, 1992) |
"Side effects of carbamazepine (CBZ), valproate (VPA) and clonazepam (CZP) are rare during long-term use but rather common and usually transient during the early phases of treatment." | 1.27 | Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy. ( Keränen, T; Sivenius, J, 1983) |
"Clonazepam was administered in three patients; one of them was completely unresponsive and two became seizure-free for a mean of 16." | 1.27 | Startle-induced epileptic seizures. ( Aguglia, U; Gastaut, H; Tinuper, P, 1984) |
"Clonazepam proved to be an efficient contributive factor in the course of a curing process since, in 70% of the cases, it produced quite a visible amelioration." | 1.26 | [Effects of clonazepam taken per os by children with rebellious epileptic encephalopathies]. ( Brun, JP; Gathier, MC; Gibert, J; Maupetit, F; Maupetit, J; Pechadre, JC, 1977) |
"Clonazepam (Antelepsin) was tested on 179 patients in 8 institutions during a period of 180 days." | 1.26 | [Treatment of epilepsy with clonazepam (Antelepsin)]. ( Arndt, R; Böhl, I; Brückner, HJ; Cammann, G; Du Chesne, HJ; Fischer, W; Hobusch, D; Knaape, HH; Müller, D; Oettinger, B; Rabending, G; Rohmann, E; Rössger, B; Schmidtsdorf, R; Vesper, J; Zettler, H, 1979) |
"Valproic acid is a promising antiepileptic drug with broad-spectrum activity, and is particularly useful in the treatment of absence and myoclonic seizures, although further clinical experience is required before it can supplant ethosuximide as the preferred drug for the treatment of absence seizures." | 1.26 | Recent advances in drug therapy for epilepsy. ( Bruni, J, 1979) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 131 (59.55) | 18.7374 |
1990's | 36 (16.36) | 18.2507 |
2000's | 26 (11.82) | 29.6817 |
2010's | 17 (7.73) | 24.3611 |
2020's | 10 (4.55) | 2.80 |
Authors | Studies |
---|---|
Brigo, F | 2 |
Igwe, SC | 2 |
Bragazzi, NL | 2 |
Lattanzi, S | 2 |
Dell'Isola, GB | 1 |
Mencaroni, E | 1 |
Fattorusso, A | 1 |
Tascini, G | 1 |
Prontera, P | 1 |
Imperatore, V | 1 |
Di Cara, G | 1 |
Striano, P | 1 |
Verrotti, A | 1 |
Logue, TC | 1 |
Huang, Y | 1 |
Benson, RJ | 1 |
Pack, AM | 1 |
Wright, JD | 1 |
D'Alton, ME | 1 |
Friedman, AM | 1 |
Tomson, T | 1 |
Battino, D | 2 |
Bromley, R | 1 |
Kochen, S | 1 |
Meador, KJ | 2 |
Pennell, PB | 1 |
Thomas, SV | 1 |
Lawal, OD | 1 |
Hume, AL | 1 |
Wen, X | 1 |
Han, X | 1 |
Wang, J | 1 |
Le Coz, J | 1 |
Chéron, G | 1 |
Nabbout, R | 1 |
Patteau, G | 1 |
Heilbronner, C | 1 |
Hubert, P | 1 |
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Oualha, M | 1 |
Chen, C | 1 |
Hao, Y | 1 |
Liang, J | 1 |
Liu, X | 1 |
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Leung, WCY | 1 |
Leung, IYH | 1 |
Chang, RSK | 1 |
Noguchi, Y | 1 |
Takaoka, M | 1 |
Hayashi, T | 1 |
Tachi, T | 1 |
Teramachi, H | 1 |
Daugaard, CA | 1 |
Pedersen, L | 1 |
Sun, Y | 1 |
Dreier, JW | 1 |
Christensen, J | 1 |
Zhang, Y | 1 |
Lian, Y | 1 |
Xie, N | 1 |
Baudou, E | 1 |
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Dimeglio, C | 1 |
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Eisermann, M | 1 |
Lardeux, C | 1 |
Nicloux, M | 1 |
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Thibert, RL | 1 |
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Suenobu, S | 1 |
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Kurokawa, T | 1 |
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Cowley, M | 1 |
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O'Brien, TJ | 1 |
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Kovács, R | 1 |
Kardos, J | 1 |
Heinemann, U | 1 |
Kann, O | 1 |
Voermans, NC | 1 |
Zwarts, MJ | 1 |
Renier, WO | 1 |
Bloem, BR | 1 |
Kecskeméti, V | 1 |
Rusznák, Z | 1 |
Riba, P | 1 |
Pál, B | 1 |
Wagner, R | 1 |
Harasztosi, C | 1 |
Nánási, PP | 1 |
Szûcs, G | 1 |
Zhao, Y | 1 |
Rui, JZ | 1 |
Li, JH | 1 |
Xiang, BR | 1 |
von Wrede, R | 1 |
Schmidt, D | 1 |
Loiseau, P | 2 |
Hertrich, O | 2 |
Callaghan, N | 1 |
O'Dwyer, R | 1 |
Keating, J | 1 |
Keränen, T | 1 |
Sivenius, J | 1 |
Mondadori, C | 2 |
Schmutz, M | 2 |
Baltzer, V | 1 |
De Paiva, VJ | 1 |
Subirana, A | 1 |
Subirana, M | 1 |
Jibiki, I | 1 |
Dincheva, S | 1 |
Baykoushev, S | 1 |
Chalukova-Atanassova, N | 1 |
Aguglia, U | 2 |
Tinuper, P | 1 |
Gastaut, H | 2 |
Murasaki, M | 1 |
Okamoto, K | 1 |
Takahashi, A | 1 |
Nagai, T | 1 |
Benoit, P | 1 |
Peutillot, A | 1 |
Dumermuth, G | 3 |
Lange, B | 2 |
Herdan, M | 2 |
Molinari, L | 1 |
Klosterskov Jensen, P | 1 |
Abild, K | 1 |
Nøhr Poulsen, M | 1 |
Sáenz-Lope, E | 1 |
Herranz-Tanarro, FJ | 1 |
Masdeu, JC | 1 |
Bufil, J | 1 |
Aminoff, MJ | 1 |
Scollo-Lavizzari, G | 1 |
Boldyrev, AI | 1 |
Engel, J | 1 |
Troupin, AS | 1 |
Crandall, PH | 1 |
Sterman, MB | 1 |
Wasterlain, CG | 1 |
Terzano, MG | 1 |
Parrino, L | 1 |
Manzoni, GC | 1 |
Mancia, D | 1 |
Lambie, DG | 3 |
Johnson, RH | 3 |
Mares, P | 7 |
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Stach, R | 1 |
Bacia, T | 1 |
Purska-Rowińska, E | 1 |
Okuszko, S | 1 |
Saenz Lope, E | 1 |
Herranz Tanarro, FJ | 1 |
Khobush, D | 1 |
Roman, E | 1 |
Kiul'ts, I | 1 |
Kammann, G | 1 |
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Avanzini, G | 1 |
Caccamo, ML | 1 |
Canger, R | 1 |
Como, ML | 1 |
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de Giambattista, M | 1 |
Franceschetti, S | 1 |
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Pardi, G | 1 |
Porro, MG | 1 |
Rovei, V | 2 |
Sanjuan, M | 2 |
Soffientini, ME | 1 |
Spina, S | 1 |
Spreafico, R | 1 |
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Hartford, E | 1 |
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Puig Abulí, M | 1 |
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Villa-Elízaga, I | 1 |
Baraczka, K | 1 |
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Perlwitz, R | 1 |
Grimmberger, E | 1 |
Schmidtsdorf, R | 2 |
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Chesler, N | 1 |
Kromberg, JG | 1 |
Hirvasniemi, A | 2 |
Herrala, P | 1 |
Leisti, J | 1 |
Badalian, LO | 1 |
Temin, PA | 1 |
Medvedev, MI | 1 |
Mukhin, KIu | 1 |
Iskander, MB | 1 |
Kharlamov, DA | 1 |
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Buchanan, N | 2 |
Sharpe, C | 1 |
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Vorlícek, J | 2 |
Huang, ZC | 2 |
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Thompson, PJ | 1 |
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Korinthenberg, R | 1 |
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Eriksson, AS | 1 |
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Nergårdh, A | 2 |
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Edge, JH | 2 |
De Sarro, G | 1 |
Di Paola, ED | 1 |
de Sarro, A | 2 |
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Ohu, M | 1 |
Yasumoto, S | 2 |
Ogawa, A | 2 |
Lang, AH | 1 |
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Sombati, S | 1 |
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Coulter, DA | 2 |
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Baglietto, MG | 1 |
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Munthe-Kaas, AW | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Prospective Study on the Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine(TCM) and Western Medicine Based on TCM Syndrome Differentiation[NCT04189367] | Phase 3 | 80 participants (Anticipated) | Interventional | 2020-06-20 | Not yet recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
20 reviews available for clonazepam and Epilepsy
Article | Year |
---|---|
Clonazepam monotherapy for treating people with newly diagnosed epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Humans; Seizures | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Eve | 2022 |
Clonazepam monotherapy for treating people with newly diagnosed epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Humans; Quality of Life; Randomi | 2019 |
A patient with epilepsy and new onset of nocturnal symptoms.
Topics: Aged; Anticonvulsants; Clonazepam; Electroencephalography; Epilepsy; Humans; Nocturnal Paroxysmal Dy | 2009 |
[Epilepsy with continuous spikes and waves during slow sleep].
Topics: Adolescent; Child; Clonazepam; Diagnosis, Differential; Drug Therapy, Combination; Electroencephalog | 2002 |
[Progressive epilepsy with mental retardation(PEMR)].
Topics: Animals; Child; Child, Preschool; Chromosomes, Human, Pair 8; Clonazepam; Diagnosis, Differential; D | 2002 |
[Benzodiazepines in the treatment of epilepsy].
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Child, Preschool; Clobazam | 1983 |
[Current progress in research and treatment of epilepsy].
Topics: Animals; Brain; Clonazepam; Disease Models, Animal; Electroencephalography; Epilepsy; Humans; Kindli | 1984 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long | 1981 |
Recent developments in the diagnosis and therapy of epilepsy.
Topics: Anticonvulsants; Biofeedback, Psychology; Carbamazepine; Clonazepam; Clorazepate Dipotassium; Condit | 1982 |
Fortnightly review: drug treatment of epilepsy.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Clobazam; Clo | 1999 |
[Long-term anticonvulsant therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Te | 1978 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, | 1979 |
[Epilepsies of infancy and early childhood (author's transl)].
Topics: Clonazepam; Electroencephalography; Epilepsy; Humans; Infant; Infant, Newborn; Infant, Newborn, Dise | 1978 |
Antiepileptic drugs and their psychotropic effects.
Topics: Affect; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Epilepsy; Humans; Mental Disorders; Psych | 1992 |
[Epileptic psychoses and their drug treatment].
Topics: Anticonvulsants; Antipsychotic Agents; Clonazepam; Diazepam; Epilepsy; Humans; Neurocognitive Disord | 1989 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Dru | 1987 |
Excessive startle syndromes: startle disease, jumping, and startle epilepsy.
Topics: Clonazepam; Diagnosis, Differential; Echolalia; Electroencephalography; Electromyography; Epilepsy; | 1986 |
Use of barbiturates and benzodiazepines in treatment of epilepsy.
Topics: Adult; Barbiturates; Benzodiazepines; Child; Clonazepam; Clorazepate Dipotassium; Diazepam; Epilepsy | 1986 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; E | 1985 |
17 trials available for clonazepam and Epilepsy
Article | Year |
---|---|
Pharmacokinetic and pharmacodynamic effects of clonazepam in children with epilepsy treated with valproate: a preliminary study.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Chromatography, Gas; Chromatography, High Pres | 2002 |
Second-line anticonvulsant treatment of neonatal seizures: a video-EEG monitoring study.
Topics: Anticonvulsants; Clonazepam; Drug Resistance; Electroencephalography; Epilepsy; Female; Humans; Infa | 2004 |
The effect and side-effects of treatment with antelepsin.
Topics: Adult; Anticonvulsants; Benzodiazepinones; Child; Clinical Trials as Topic; Clonazepam; Electroencep | 1984 |
Some comments on the treatment of epilepsy by clonazepam with special reference to serum concentrations and EEG beta activity.
Topics: Benzodiazepinones; Beta Rhythm; Child; Clinical Trials as Topic; Clonazepam; Electroencephalography; | 1982 |
Clonazepam in the treatment of drug-resistant epilepsy: a clinical short and long term follow-up study.
Topics: Adult; Benzodiazepinones; Clinical Trials as Topic; Clonazepam; Drug Resistance; Electroencephalogra | 1980 |
[The enkorat treatment of infantile spasms and the Lennox-Gastaut syndrome].
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsy; E | 1994 |
Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cl | 1996 |
Clonazepam disposition in pediatric patients.
Topics: Acetylation; Adolescent; Anticonvulsants; Biotransformation; Child; Child, Preschool; Clonazepam; Ep | 1996 |
The effectiveness of clonazepam on the Rolandic discharges.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Electroencephalography; Epileps | 1997 |
Reduction of epileptiform activity in response to low-dose clonazepam in children with epilepsy: a randomized double-blind study.
Topics: Anticonvulsants; Child; Child, Preschool; Clonazepam; Cross-Over Studies; Double-Blind Method; Drug | 2000 |
Epilepsy and antiepileptic drug therapy in juvenile neuronal ceroid lipofuscinosis.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbidity; | 2000 |
Valproate sodium: evaluation of so-called psychotropic effect. A controlled study.
Topics: Adolescent; Adult; Clinical Trials as Topic; Clonazepam; Epilepsy; Female; Humans; Male; Mental Proc | 1977 |
Clonazepam: its efficacy in association with phenytoin and phenobarbital in mental patients with generalized major motor seizures.
Topics: Benzodiazepinones; Clinical Trials as Topic; Clonazepam; Double-Blind Method; Drug Therapy, Combinat | 1978 |
Studies on EEG activities in the beta band.
Topics: Adolescent; Anticonvulsants; Beta Rhythm; Child; Clinical Trials as Topic; Clonazepam; Computers; El | 1977 |
A double-blind study of clonazepam in the treatment of therapy-resistant epilepsy in children.
Topics: Adolescent; Benzodiazepinones; Child; Child, Preschool; Clinical Trials as Topic; Clonazepam; Drug E | 1977 |
Treatment of epilepsy with clonazepam and its effect on other anticonvulsants.
Topics: Adolescent; Adult; Ambulatory Care; Benzodiazepinones; Brain; Child; Clinical Trials as Topic; Clona | 1977 |
[Our experiences with a new antiepileptic drug clonazepam].
Topics: Adolescent; Adult; Benzodiazepinones; Child; Child, Preschool; Clinical Trials as Topic; Clonazepam; | 1976 |
183 other studies available for clonazepam and Epilepsy
Article | Year |
---|---|
Expanding the genetic and clinical characteristics of Protocadherin 19 gene mutations.
Topics: Cadherins; Carbamazepine; Child, Preschool; Clonazepam; Epilepsy; Female; Humans; Infant; Mutation; | 2022 |
Use of antiepileptic drugs by trimester.
Topics: Anticonvulsants; Clonazepam; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Pregnancy; Retros | 2022 |
Utilization of Antiseizure Medications in Women of Childbearing Age With Epilepsy and Nonepilepsy Indications: A Retrospective Cohort Study.
Topics: Anticonvulsants; Clonazepam; Diazepam; Epilepsy; Female; Gabapentin; Humans; Lamotrigine; Lorazepam; | 2023 |
A serious adverse drug reaction probably induced by clonazepam: a case report of myotoxicity.
Topics: Adult; Anticonvulsants; Clonazepam; Drug Therapy, Combination; Epilepsy; Female; Humans; Myotoxicity | 2019 |
Diagnostic evaluation and management of seizures and status epilepticus in children with known epilepsy or new-onset seizures: A retrospective and comparative analysis.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Clonazepam; Diazepam; Epilepsy; Female; Hospit | 2020 |
Congenital microcephaly with early onset epileptic encephalopathy caused by ASNS gene mutation: A case report.
Topics: Anticonvulsants; Aspartate-Ammonia Ligase; China; Clonazepam; Electroencephalography; Epilepsy; Huma | 2020 |
Factors associated with depression in people with epilepsy: a retrospective case-control analysis.
Topics: Adult; Anticonvulsants; Case-Control Studies; Clonazepam; Depression; Epilepsy; Female; Humans; Male | 2020 |
Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database.
Topics: Anticonvulsants; Carbamazepine; Clobazam; Clonazepam; Databases, Factual; Drug Therapy, Combination; | 2020 |
Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Denmark; Developmen | 2020 |
Early onset epileptic encephalopathy with a novel GABRB3 mutation treated effectively with clonazepam: A case report.
Topics: Age of Onset; Anticonvulsants; Child; Clonazepam; Codon, Nonsense; Developmental Disabilities; DNA M | 2017 |
Etiology of neonatal seizures and maintenance therapy use: a 10-year retrospective study at Toulouse Children's hospital.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Cohort Studies; Databases, Factual; Dose-Response Relati | 2019 |
Not all myoclonic jerking and tonic posturing in the neonate is epilepsy.
Topics: Anticonvulsants; Clonazepam; Consanguinity; Diagnosis, Differential; Electroencephalography; Epileps | 2014 |
[Gliomas: fighting until the end against epilepsy; administration of antiepileptic drugs in the end-of-life phase].
Topics: Anticonvulsants; Clonazepam; Epilepsy; Glioma; Humans; Midazolam; Seizures; Terminal Care | 2014 |
[Convulsions due to an interaction between anti-epileptic drugs and rifampicin].
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Cytochrome P-450 Enzyme System; Drug Interactions; Epile | 2014 |
Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series.
Topics: Adult; Aged; Anticonvulsants; Benzodiazepines; Child; Clobazam; Clonazepam; Epilepsy; Female; Humans | 2014 |
A granulocytosis associated with rufinamide: A case report.
Topics: Agranulocytosis; Anticonvulsants; Child; Clonazepam; Epilepsy; Humans; Male; Triazoles; Valproic Aci | 2015 |
A rare paroxysmal movement disorder: mixed type of paroxysmal dyskinesia.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Chorea; Clonazepam; Diagnosis, Differential; Drug Therap | 2014 |
The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Clon | 2016 |
Clobazam and clonazepam use in epilepsy: Results from a UK database incident user cohort study.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; | 2016 |
Clonazepam oral droplets for the treatment of acute epileptic seizures.
Topics: Acute Disease; Administration, Oral; Animals; Anticonvulsants; Clonazepam; Epilepsy; Intestinal Abso | 2008 |
Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options.
Topics: Adolescent; Adult; Angelman Syndrome; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbid | 2009 |
Isobolographic characterization of interactions of levetiracetam with the various antiepileptic drugs in the mouse 6 Hz psychomotor seizure model.
Topics: Animals; Anticonvulsants; Clonazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug | 2009 |
PLEDs in an infant with congenital protein C deficiency: a case report.
Topics: Anticonvulsants; Asian People; Clonazepam; Electroencephalography; Epilepsy; Female; Functional Late | 2010 |
Dissolving oral clonazepam wafers in the acute treatment of prolonged seizures.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, | 2010 |
Late-onset nocturnal intractable seizure during sleep: what is the origin?
Topics: Anticonvulsants; Clonazepam; Epilepsy; Follow-Up Studies; Humans; Male; Middle Aged; Polysomnography | 2010 |
Prevalence of Epilepsy among Cataract Patients.
Topics: Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cataract; Cataract Extraction; Clonazepa | 2010 |
Craniosynostosis following hemispherectomy in a 2.5-month-old boy with intractable epilepsy.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Clonazepam; Craniosynostoses; Craniotomy; Electroencep | 2011 |
Panic attacks in the differential diagnosis and treatment of resistant epilepsy.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Tricyclic; Clomipramine; Clonazepam; Diagnosis, Diffe | 2002 |
[Clinical features and treatment of refractory epilepsy in children].
Topics: Adolescent; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam | 2001 |
Absence seizures in patients with localization-related epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Electroencephalogra | 2003 |
Urinary retention due to clonazepam in a child with dyskinetic cerebral palsy.
Topics: Anticonvulsants; Cerebral Palsy; Child, Preschool; Clonazepam; Diagnosis, Differential; Emergency Me | 2004 |
Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats.
Topics: Adrenergic Agents; Aminoglutethimide; Amygdala; Animals; Anticonvulsants; Clonazepam; Disease Models | 2005 |
Tiagabine-induced generalised non convulsive status epilepticus in patients with lesional focal epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Clonazepam; Electroencephalography; Epilepsy; Female; Humans; Ma | 2005 |
REM behavior disorder associated with epileptic seizures.
Topics: Aged; Anticonvulsants; Brain; Clonazepam; Electroencephalography; Epilepsy; Humans; Male; Middle Age | 2005 |
Mitochondrial calcium ion and membrane potential transients follow the pattern of epileptiform discharges in hippocampal slice cultures.
Topics: Animals; Animals, Newborn; Calcium; Calcium Signaling; Clonazepam; Dose-Response Relationship, Radia | 2005 |
[Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy].
Topics: Adult; Anticonvulsants; Cesarean Section; Clonazepam; Diazepam; Epilepsy; Epilepsy, Generalized; Epi | 2005 |
Norfluoxetine and fluoxetine have similar anticonvulsant and Ca2+ channel blocking potencies.
Topics: Animals; Anticonvulsants; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signa | 2005 |
[Rapid analysis of antiepileptic drugs in human plasma by micellar electrokinetic capillary chromatography].
Topics: Anticonvulsants; Buffers; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Clonazep | 2006 |
[Epilepsy: which therapy in acute care?].
Topics: Acute Disease; Anticonvulsants; Benzodiazepines; Clobazam; Clonazepam; Diazepam; Epilepsy; Humans; L | 2006 |
The influence of antiepileptic drugs on the electroencephalogram: a review of controlled clinical studies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Electroencephalography; Epil | 1982 |
[Ataractic treatment in psychiatry and general medicine. 2. Tranquillant = tranquilizers = daytime sedatives].
Topics: Anticonvulsants; Antidepressive Agents; Benzodiazepines; Carbamazepine; Chemistry, Pharmaceutical; C | 1983 |
Unnecessary polypharmacy in patients with frequent seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Epi | 1984 |
Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy.
Topics: Abnormalities, Drug-Induced; Arousal; Benzodiazepinones; Carbamazepine; Chemical and Drug Induced Li | 1983 |
Potentiation of the anticonvulsant effects of antiepileptic drugs by "nootropics"; a potential new therapeutic approach.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Synergis | 1984 |
[Plasma levels of antiepileptic agents in the treatment of epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interac | 1984 |
Startle-induced epileptic seizures.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Child; Child, Preschool; | 1984 |
Psychomotor status--a female case in the 34th week of pregnancy.
Topics: Adult; Carbamazepine; Clonazepam; Drugs, Chinese Herbal; Electroencephalography; Epilepsy; Epilepsy, | 1983 |
[Rivotril].
Topics: Benzodiazepinones; Clonazepam; Epilepsy; Humans | 1984 |
[Application of beta-rhythm quantification to the treatment of epilepsy].
Topics: Benzodiazepinones; Beta Rhythm; Child; Child, Preschool; Clonazepam; Electroencephalography; Epileps | 1983 |
Serum concentration of clonazepam after rectal administration.
Topics: Adult; Benzodiazepinones; Clonazepam; Epilepsy; Female; Humans; Injections, Intravenous; Male; Middl | 1983 |
Familial photosensitive epilepsy: effectiveness of clonazepam.
Topics: Adolescent; Adult; Benzodiazepinones; Clonazepam; Electroencephalography; Epilepsy; Female; Humans; | 1984 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; | 1981 |
[Clinical evaluation of certain modern antiepileptic preparations].
Topics: Anticonvulsants; Automatism; Carbamazepine; Child; Clonazepam; Diencephalon; Epilepsy; Epilepsy, Abs | 1982 |
Seizures triggered by blinking when beginning to speak.
Topics: Blinking; Clonazepam; Electroencephalography; Epilepsy; Humans; Male; Middle Aged; Speech | 1983 |
Serum concentration of clonazepam and the therapeutic effect of the drug.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Clonazepam; Epilepsy; Female; Humans; Male; M | 1983 |
Influence of clonazepam on thalamocortical phenomena in rats.
Topics: Animals; Benzodiazepinones; Cerebral Cortex; Clonazepam; Electric Stimulation; Electroencephalograph | 1983 |
[Ataractic treatment in psychiatry and general medicine. Overview of preparations, 3].
Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Chlorprothixene; Clobaza | 1983 |
Clonazepam Therapy in a case of primary reading epilepsy.
Topics: Adult; Benzodiazepinones; Clonazepam; Epilepsy; Humans; Male; Reading | 1982 |
[Treatment of therapeutically resistant epileptic seizures in childhood with clonazepam (antelepsin)].
Topics: Adolescent; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Electroencephalography; Epilepsy | 1982 |
Plasma levels and clinical effects of antiepileptic drugs in pregnant epileptic patients and their newborns.
Topics: Adult; Anticonvulsants; Clonazepam; Epilepsy; Female; Humans; Infant, Newborn; Phenobarbital; Phenyt | 1980 |
Simple and specific high performance liquid chromatographic method for the routine monitoring of clonazepam in plasma.
Topics: Adult; Benzodiazepinones; Chromatography, High Pressure Liquid; Clonazepam; Epilepsy; Flunitrazepam; | 1980 |
Epileptic seizures induced by clonazepam.
Topics: Adolescent; Benzodiazepinones; Clonazepam; Electroencephalography; Epilepsy; Female; Humans | 1981 |
[Use of naloxone in the treatment of clonazepam poisoning].
Topics: Benzodiazepinones; Child; Clonazepam; Epilepsy; Female; Humans; Naloxone | 1981 |
Possible drug interaction in chronic treatment of epileptic patients: serum level studies.
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Chronic Disease; Clonazepam; Drug Interac | 1980 |
[Immediate effect of intravenous clonazepam on the EEG].
Topics: Adolescent; Adult; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Electroencephalography; E | 1980 |
Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs.
Topics: Adult; Autistic Disorder; Child, Preschool; Clonazepam; Developmental Disabilities; Epilepsy; Family | 1994 |
Northern epilepsy syndrome: clinical course and the effect of medication on seizures.
Topics: Adolescent; Adult; Age Factors; Age of Onset; Anticonvulsants; Central Nervous System Diseases; Chil | 1995 |
Clonazepam withdrawal in 13 patients with active epilepsy and drug side effects.
Topics: Adolescent; Adult; Child; Child, Preschool; Clonazepam; Epilepsy; Female; Humans; Male; Middle Aged; | 1994 |
Stable anticonvulsant action of benzodiazepines during development in rats.
Topics: Aging; Animals; Animals, Newborn; Anticonvulsants; Clonazepam; Electric Stimulation; Electroencephal | 1993 |
[Diazepam-induced EEG changes as a predictor of the outcome of epilepsy].
Topics: Clonazepam; Diazepam; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Male; Pro | 1993 |
Discontinuation of clonazepam in patients with active epilepsy.
Topics: Adolescent; Adult; Clonazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Elect | 1993 |
[Drug therapy and its problems in epilepsy].
Topics: Clonazepam; Diazepam; Emergencies; Epilepsy; Humans | 1993 |
The prognostic significance of diazepam-induced EEG changes in epilepsy: a follow-up study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Beta Rhythm; Child; Clonazepam; Diazepam; Drug Therapy, Co | 1993 |
Intermittent clonazepam treatment prevents anticonvulsant tolerance in mice.
Topics: Animals; Clonazepam; Disease Models, Animal; Drug Administration Schedule; Drug Tolerance; Epilepsy; | 1993 |
Paralytic ileus in a fetus-neonate after maternal intake of benzodiazepine.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Epilepsy; Female; Fetal Diseases; Humans; Infant, | 1995 |
Tolerance to anticonvulsant effects of some benzodiazepines in genetically epilepsy prone rats.
Topics: Acoustic Stimulation; Administration, Oral; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiaz | 1996 |
Rhythmic slow activity in benign childhood epilepsy with centrotemporal spikes.
Topics: Child; Child, Preschool; Clonazepam; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; | 1997 |
Neurophysiological findings in the northern epilepsy syndrome.
Topics: Adolescent; Adult; Age Factors; Age of Onset; Anticonvulsants; Brain; Child; Child, Preschool; Clona | 1997 |
Physiological and pharmacological alterations in postsynaptic GABA(A) receptor function in a hippocampal culture model of chronic spontaneous seizures.
Topics: Animals; Anticonvulsants; Cells, Cultured; Chloride Channels; Clonazepam; Disease Models, Animal; Ep | 1997 |
Benzodiazepine (BDZ) treatment of benign childhood epilepsy with centrotemporal spikes (BECCT)
Topics: Anticonvulsants; Child; Clonazepam; Electroencephalography; Epilepsy; GABA Modulators; Humans | 1997 |
Antiepileptic drug augmentation for treatment-resistant depression.
Topics: Alprazolam; Anticonvulsants; Antidepressive Agents; Clonazepam; Comorbidity; Depressive Disorder; Di | 1997 |
Improved selectivity for high-performance liquid chromatographic determination of clonazepam in plasma of epileptic patients.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Clonazepam; Epilepsy; Humans; Reference Stand | 1998 |
Landau Kleffner syndrome.
Topics: Adolescent; Anticonvulsants; Clonazepam; Epilepsy; GABA Modulators; Humans; Hyperkinesis; Landau-Kle | 1998 |
Human neuronal gamma-aminobutyric acid(A) receptors: coordinated subunit mRNA expression and functional correlates in individual dentate granule cells.
Topics: Adolescent; Adult; Animals; Cells, Cultured; Clonazepam; Dentate Gyrus; Epilepsy; Female; Gene Expre | 1999 |
Seizure-inducing paradoxical reaction to antiepileptic drugs.
Topics: Anticonvulsants; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Hu | 2000 |
Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs.
Topics: Animals; Anticonvulsants; Calcium; Carbamazepine; Clonazepam; Electrophysiology; Epilepsy; Evoked Po | 2000 |
Influence of age and comedication on steady-state clonazepam serum level-dose ratios in Japanese epileptic patients.
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Clonazepam; Drug Interactions; Dr | 2001 |
Clobazam shows a different antiepileptic action profile from clonazepam and zonisamide in Ihara epileptic rats.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Circadian Rhythm; Clobazam; Clonazep | 2002 |
[Effects of clonazepam taken per os by children with rebellious epileptic encephalopathies].
Topics: Administration, Oral; Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepinones; Child; Child, Presc | 1977 |
[Therapy of resistant forms of epilepsy using rivotril].
Topics: Adult; Age Factors; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Drug Resistance; Epileps | 1978 |
Some aspects of the clinical use of clonazepam in refractory epilepsy.
Topics: Adolescent; Adult; Ataxia; Benzodiazepinones; Child; Clonazepam; Depression; Drug Therapy, Combinati | 1979 |
[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Clonazepam; Dia | 1977 |
[Drug therapy of epilepsy].
Topics: Anticonvulsants; Carbamazepine; Chlordiazepoxide; Clonazepam; Diazepam; Electroencephalography; Epil | 1975 |
Drug interactions during anticonvulsant therapy in childhood: diphenylhydantoin, primidone, phenobarbitone, clonazepam, nitrazepam, carbamazepin and dipropylacetate.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; | 1977 |
Plasma levels of di-no-propylacetate and clonazepam in epileptic patients.
Topics: Adolescent; Adult; Benzodiazepinones; Child; Clonazepam; Epilepsy; Female; Humans; Male; Valerates; | 1977 |
Choice of drug therapy in epilepsy.
Topics: Acetazolamide; Anticonvulsants; Benzodiazepines; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; | 1977 |
Concomitant use of clonazepam and valproic acid in treatment of epileptic seizures.
Topics: Benzodiazepinones; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Humans; Male; Valproic Ac | 1979 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; | 1979 |
Recent advances in drug therapy for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phen | 1979 |
Comparative trial of valproate sodium and clonazepam in chronic epilepsy.
Topics: Adult; Ataxia; Benzodiazepinones; Chronic Disease; Clonazepam; Drug Therapy, Combination; Epilepsy; | 1979 |
Combination of clonazepam and sodium valproate in the treatment of refractory epileptic seizures in 12 children.
Topics: Benzodiazepinones; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Humans; Seizures; Valproi | 1979 |
Recent advances in drug therapy of some forms of childhood epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Therapy, Combination; Epilepsy; Hu | 1979 |
Sodium valproate and clonazepam in the treatment of intractable epilepsy.
Topics: Adolescent; Adult; Benzodiazepinones; Child; Clonazepam; Drug Evaluation; Epilepsy; Epilepsy, Absenc | 1977 |
Medical treatment of epilepsy: part I.
Topics: Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combina | 1978 |
[A clinical study of the clonazepam in the treatment of epilepsy (author's transl)].
Topics: Adolescent; Adult; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Electroencephalography; E | 1978 |
Psychosis or epilepsy? Differentiation in a complex case.
Topics: Adolescent; Brain; Child Behavior; Clonazepam; Diagnosis, Differential; Electroencephalography; Epil | 1979 |
Effectiveness of clonazepan in startle-induced seizures.
Topics: Adolescent; Benzodiazepinones; Child; Clonazepam; Epilepsy; Female; Humans; Male; Reflex, Startle | 1979 |
[Treatment of epilepsy with clonazepam (Antelepsin)].
Topics: Benzodiazepinones; Clonazepam; Drug Evaluation; Epilepsy; Humans | 1979 |
[Antiepileptic activity of clonazepam, a benzodiazepine antiepileptic (2). Antiepileptic effects of intravenous injection of clonazepam manifested in EEG].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Benzodiazepinones; Child; Clonazepam; Diazepam; Electroenc | 1977 |
The utility of clonazepam in epilepsy of various types. Observations with 22 childhood cases.
Topics: Adolescent; Adult; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Drug Administration Sched | 1978 |
Acute and chronic antiepileptic drug effect on the T complex interhemispheric latency difference.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Auditory Pathways; Brain; Child; Clonazepam; Electroenceph | 1978 |
[Rivotril treatment of epilepsy in children: an evaluation].
Topics: Age Factors; Clonazepam; Drug Evaluation; Epilepsy; Humans | 1978 |
Clonazepam in the treatment of epilepsy.
Topics: Benzodiazepinones; Clonazepam; Epilepsy; Humans | 1978 |
Successful treatment of primary reading epilepsy with clonazepam.
Topics: Adult; Benzodiazepinones; Clonazepam; Epilepsy; Female; Humans; Reading | 1978 |
[Advances in the management of epilepsy].
Topics: Anticonvulsants; Clonazepam; Epilepsy; Humans | 1978 |
[Electroencephalographic changes induced by clonazepam infusion: predictive value for chronic treatment of epilepsy: preliminary data].
Topics: Adolescent; Benzodiazepinones; Brain; Child; Clonazepam; Electroencephalography; Epilepsy; Humans; I | 1978 |
Clonazepam in epilepsy.
Topics: Adolescent; Adult; Benzodiazepinones; Cerebral Palsy; Child; Child, Preschool; Clonazepam; Epilepsy; | 1979 |
[Measurement of the blood concentration of antiepileptic drugs. II Special cases].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbi | 1975 |
Proposals on antiepileptic pharmacotherapy for use in developing countries.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Developing Countries; Diazepam | 1976 |
The anticonvulsant effect of sodium valproate and clonazepam in the management of intractable epilepsy.
Topics: Benzodiazepinones; Clonazepam; Drug Evaluation; Epilepsy; Humans; Valerates; Valproic Acid | 1976 |
Treatment of epileptic seizures with clonazepam. A reappraisal.
Topics: Administration, Oral; Adolescent; Adult; Ataxia; Benzodiazepinones; Child; Clonazepam; Drug Administ | 1975 |
Sensible prescribing. XI.--Juvenile and adult epilepsy.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epile | 1975 |
Sodium valproate in the management of intractable epilepsy: comparison with clonazepam.
Topics: Adolescent; Adult; Benzodiazepinones; Child; Clonazepam; Epilepsy; Epilepsy, Tonic-Clonic; Female; H | 1975 |
Diagnosis and treatment of minor motor seizures.
Topics: Child; Child, Preschool; Clonazepam; Electroencephalography; Epilepsy; Epilepsy, Absence; Humans; In | 1976 |
Clonazepam in the treatment of epilepsy. A clinical long-term follow-up study.
Topics: Adolescent; Adult; Aged; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Drug Evaluation; Ep | 1976 |
[Rivotril (Clonazepam), a new antiepileptic drug].
Topics: Adolescent; Adult; Animals; Anticonvulsants; Benzodiazepinones; Child; Child, Preschool; Clonazepam; | 1977 |
Clonazepam: a new anticonvulsant.
Topics: Anticonvulsants; Benzodiazepinones; Clonazepam; Electroencephalography; Epilepsy; Humans | 1977 |
Lack of effect of clonazepam on serum levels of diphenylhydantoin, phenobarbital and carbamazepine.
Topics: Adolescent; Adult; Benzodiazepinones; Carbamazepine; Child; Clonazepam; Drug Interactions; Drug Ther | 1977 |
A clinical and electroencephalographic study on anti-epileptic activity of clonazepam. Relationship between clinical effects of oral administration and electroencephalographic effects of intravenous administration.
Topics: Administration, Oral; Adolescent; Aged; Benzodiazepinones; Brain; Child; Clonazepam; Electroencephal | 1977 |
Clinical and EEG response to clonazepam in four patients with self-induced photosensitive epilepsy.
Topics: Adolescent; Adult; Benzodiazepinones; Child; Clonazepam; Electroencephalography; Epilepsy; Female; H | 1976 |
Benzodiazepine anticonvulsant.
Topics: Benzodiazepinones; Clonazepam; Epilepsy; Humans | 1976 |
Clonazepam: a review of its pharmacological properties and therapeutic efficacy in epilepsy.
Topics: Absorption; Animals; Antitussive Agents; Benzodiazepinones; Brain; Cats; Clonazepam; Drug Interactio | 1976 |
[Epilepsy refractary to usual treatment: the effect of clonazepam (author's transl)].
Topics: Adolescent; Benzodiazepinones; Child; Child, Preschool; Chronic Disease; Clonazepam; Drug Evaluation | 1976 |
[Antiepileptic activity of clonazepam--an antiepileptic benzodiazepine derivative].
Topics: Adolescent; Benzodiazepinones; Child; Clonazepam; Electroencephalography; Epilepsy; Epilepsy, Tempor | 1976 |
Evaluation of clonazepam in the treatment of epilepsies.
Topics: Benzodiazepinones; Child; Clonazepam; Electroencephalography; Epilepsy; Humans; Infusions, Parentera | 1976 |
Sodium valproate and clonazepam for epilepsy.
Topics: Adult; Benzodiazepinones; Child; Clonazepam; Epilepsy; Humans; Valproic Acid | 1975 |
[Sequential statistical analysis. New applications in clinical problems].
Topics: Azathioprine; Clonazepam; Cyclophosphamide; Duodenal Ulcer; Epilepsy; Humans; Kidney Diseases; Stati | 1975 |
Photically induced epilepsy in Papio papio as a model for drug studies.
Topics: Acetylcholine; Animals; Carbamazepine; Clonazepam; Diazepam; Disease Models, Animal; Dopamine; Dose- | 1975 |
[Current viewpoints in drug treatment of epilepsy, with reference to the most common drugs in current use].
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin | 1975 |
[Clonazepam for long-term therapy of epilepsy in childhood].
Topics: Benzodiazepinones; Child; Child, Preschool; Clonazepam; Epilepsy; Female; Humans; Infant; Infant, Ne | 1975 |
[Drug information: clonazepam (Rivotril, Roche)].
Topics: Benzodiazepinones; Clonazepam; Epilepsy; Humans | 1975 |
Letter: Use of clonazepam in epilepsy.
Topics: Benzodiazepinones; Child; Clonazepam; Epilepsy; Humans; Male | 1975 |
Clinical experiences with a new anticonvulsant Ro 5-4023 (clonazepam-Rivotrilr).
Topics: Adolescent; Adult; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Epilepsy; Female; Humans; | 1975 |
Pharmacokinetics and side-effects of clonazepam and its 7-amino-metabolite in man.
Topics: Adolescent; Adult; Aged; Benzodiazepinones; Biotransformation; Child; Clonazepam; Drug Interactions; | 1975 |
A simple and sensitive gas chromatographic method for the determination of clonazepam in human plasma.
Topics: Benzodiazepinones; Chromatography, Gas; Clonazepam; Epilepsy; Humans; Solvents; Time Factors | 1976 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; | 1976 |
[Serious psychological symptoms caused by clonazepam].
Topics: Adolescent; Benzodiazepinones; Child; Child Behavior Disorders; Clonazepam; Epilepsy; Humans; Male; | 1976 |
Influence of phenobarbital on ECoG phenomena induced by metrazol in rats during ontogenesis.
Topics: Aging; Animals; Cerebral Cortex; Clonazepam; Disease Models, Animal; Dose-Response Relationship, Dru | 1992 |
Effects of clonazepam on picrotoxin-induced convulsions.
Topics: Animals; Anticonvulsants; Clonazepam; Dose-Response Relationship, Drug; Epilepsy; Injections, Intrap | 1992 |
[The effect of clonazepam on experimental epilepsy induced by electrostimulation].
Topics: Animals; Clonazepam; Electric Stimulation; Electroencephalography; Epilepsy; Female; Male; Rabbits | 1992 |
Tolerance to anticonvulsant effects of clobazam, diazepam, and clonazepam in genetically epilepsy prone rats.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepino | 1992 |
Reduction of seizure frequency by clonazepam during cobalt experimental epilepsy.
Topics: Animals; Clonazepam; Cobalt; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Fem | 1992 |
Clonazepam and 7-aminoclonazepam in human plasma.
Topics: Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Chromatography, High Pressure Liqu | 1991 |
The action of clonazepam against seizures induced by N-methyl-D-aspartate in rats during ontogenesis.
Topics: Aging; Animals; Clonazepam; Epilepsy; Male; N-Methylaspartate; Rats; Rats, Inbred Strains | 1991 |
Clonazepam serum levels in epileptic patients determined simply and rapidly by high-performance liquid chromatography using a solid-phase extraction column.
Topics: Chromatography, High Pressure Liquid; Clonazepam; Epilepsy; Humans; Monitoring, Physiologic; Reprodu | 1991 |
Monoamine turnover in the brain of mice during development of tolerance to the anticonvulsant effect of clonazepam.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Clonazepam; Drug Tolerance; Epilepsy; Male; Mice | 1991 |
[Primary reading epilepsy: therapeutic efficacy of clonazepam in one case].
Topics: Adolescent; Clonazepam; Electroencephalography; Epilepsy; Humans; Male; Reading | 1990 |
[Therapeutic drug monitoring of clonazepam, nitrazepam and diazepam].
Topics: Age Factors; Biological Availability; Chromatography, Gas; Chromatography, High Pressure Liquid; Chr | 1990 |
The prevalence of adverse reactions to anticonvulsants in children with epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combi | 1989 |
Differences in the duration of the anticonvulsant action of clonazepam during ontogenesis in rats.
Topics: Animals; Anticonvulsants; Clonazepam; Dose-Response Relationship, Drug; Epilepsy; Male; Pentylenetet | 1989 |
Utilization of benzodiazepines for the study of the experimental epileptic seizures.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Clonazepam; Clorazepate Dipotassium; Disease Models | 1985 |
[Some suggestions on epileptic psychoses, their differential diagnosis and therapy].
Topics: Anticonvulsants; Antipsychotic Agents; Clonazepam; Dementia; Diagnosis, Differential; Diazepam; Drug | 1986 |
Oral benzodiazepines as prophylaxis for epilepsy.
Topics: Administration, Oral; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clobazam; Clonazepam; | 1986 |
Action of clonazepam and clorazepate on cortical self-sustained after-discharges in the rat.
Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Clonazepam; Clorazepate Dipotassium; Disease Models, | 1988 |
Synergistic effects of oxiracetam and piracetam in combination with antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Drug Synergism; Drug Therapy, Combination; Epil | 1986 |
[Epilepsy with continuous discharges during slow-wave sleep. Treatment with clobazam].
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Clo | 1986 |
Status epilepticus within the Lennox-Gastaut syndrome: clinical characteristics and management.
Topics: Child; Clonazepam; Electroencephalography; Epilepsy; Humans; Male; Status Epilepticus; Syndrome; Val | 1987 |
[Multiple types of seizure induced by clonazepam in an epileptic patient].
Topics: Child; Clonazepam; Electroencephalography; Epilepsy; Humans; Male | 1988 |
Influence of concurrent administration of carbamazepine on the plasma concentrations of clonazepam.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Dr | 1988 |
The use of long-term clonazepam (CZP) monotherapy in previously untreated epileptics.
Topics: Clonazepam; Epilepsy; Humans | 1988 |
Benzodiazepine-induced epileptiform activity in vitro.
Topics: Animals; Clonazepam; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Neurons; R | 1987 |
Clinical effects and plasma concentrations of long-term clonazepam monotherapy in previously untreated epileptics.
Topics: Adolescent; Adult; Child; Child, Preschool; Clonazepam; Electroencephalography; Epilepsy; Female; Hu | 1987 |
Carbamazepine, clonazepam use during pregnancy.
Topics: Abnormalities, Drug-Induced; Benzodiazepinones; Carbamazepine; Clonazepam; Epilepsy; Female; Humans; | 1986 |
Benzodiazepines in the treatment of children with epilepsy.
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Child; Child, Preschool; Clobazam; Clonazep | 1986 |
Clonazepam monotherapy for epilepsy in childhood.
Topics: Adolescent; Ataxia; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Electroencephalography; | 1985 |
Alterations in transient visual-evoked potentials induced by clonazepam and sodium valproate.
Topics: Adolescent; Adult; Benzodiazepinones; Brain; Child; Clonazepam; Epilepsy; Evoked Potentials, Visual; | 1985 |
Treatment of seizure disorders and myoclonus.
Topics: Benzodiazepinones; Clonazepam; Epilepsies, Myoclonic; Epilepsy; Humans | 1985 |
Paroxysmal awakenings from sleep associated with excessive daytime somnolence: a form of nocturnal epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Arousal; Clonazepam; Electroencephalography; Epilepsy; Female; H | 1986 |
Choreoathetosis and clonazepam.
Topics: Adolescent; Athetosis; Benzodiazepinones; Chorea; Clonazepam; Epilepsy; Humans; Male; Substance With | 1985 |
Phenytoin/clonazepam interaction.
Topics: Adult; Benzodiazepinones; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans | 1985 |
[Convulsive crises in childhood].
Topics: Clonazepam; Crying; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Mi | 1985 |
Side effects of clonazepam therapy.
Topics: Adolescent; Adult; Aggression; Ataxia; Benzodiazepinones; Clonazepam; Drug Interactions; Epilepsy; E | 1974 |
Chuckling and glugging seizures at night -- sylvian spike epilepsy.
Topics: Child; Clonazepam; Electroencephalography; Epilepsy; Humans; Laughter; Male; Migraine Disorders; Phe | 1974 |