clonazepam has been researched along with Dyskinesia, Drug-Induced in 30 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
| Excerpt | Relevance | Reference |
|---|---|---|
| " I report a patient who developed the syndrome during treatment for schizophrenia with the antipsychotic agent molindone hydrochloride." | 7.68 | Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen. ( Sandyk, R, 1990) |
| " Auditory hallucinations had developed 25 years previously, for which haloperidol had been prescribed." | 3.74 | Methamphetamine psychosis in which tardive dystonia was successfully treated with clonazepam. ( Inada, T; Oda, T; Yamamoto, N, 2007) |
| " I report a patient who developed the syndrome during treatment for schizophrenia with the antipsychotic agent molindone hydrochloride." | 3.68 | Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen. ( Sandyk, R, 1990) |
| " Tolerance developed to the antidyskinetic effect of clonazepam in the five patients whose long-term use of the drug was followed, but a 2-week clonazepam-free period recaptured its antidyskinetic effect." | 2.67 | Clonazepam treatment of tardive dyskinesia: a practical GABAmimetic strategy. ( Jacobson, R; Kaup, BA; Nguyen, JA; Strauss, ME; Tamminga, CA; Thaker, GK, 1990) |
| "Chlorpromazine was found to be significantly better than remoxipride on the dropout rate due to inefficacy, Clinical Global Impression (CGI) of severity of illness and Brief Psychiatric Rating Scale (BPRS)." | 2.67 | A placebo-controlled clinical trial of remoxipride and chlorpromazine in newly admitted schizophrenic patients with acute exacerbation. ( Chouinard, G, 1990) |
| "Clonazepam was found to be significantly more efficacious than lithium in reducing manic symptoms despite the fact that during clonazepam treatment less patients required PRNs of haloperidol." | 2.65 | Antimanic effect of clonazepam. ( Annable, L; Chouinard, G; Young, SN, 1983) |
| "Vitamin B12 deficiency is a treatable cause of failure to thrive and developmental regression, involuntary movements, and anemia." | 1.39 | Involuntary movements misdiagnosed as seizure during vitamin B12 treatment. ( Belgemen, T; Carman, KB; Yis, U, 2013) |
| "Ziprasidone was stopped in by tapering 20 mg/day, but the involuntary movements continued and even exacerbated." | 1.35 | Ziprasidone induced tardive cervical dystonia. ( Altun, NS; Budak, F; Dündar, S; Kutlu, A, 2009) |
| "Clonazepam was also more effective for drug-free patients and those receiving low doses of neuroleptics than for all patients given phenobarbital and for clonazepam patients taking high doses of neuroleptics." | 1.26 | Clonazepam and phenobarbital in tardive dyskinesia. ( Bobruff, A; Cole, JO; Gardos, G; Moore, P; Rapkin, RM; Tarsy, D, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (23.33) | 18.7374 |
| 1990's | 8 (26.67) | 18.2507 |
| 2000's | 11 (36.67) | 29.6817 |
| 2010's | 4 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bergman, H | 1 |
| Bhoopathi, PS | 1 |
| Soares-Weiser, K | 1 |
| Carman, KB | 1 |
| Belgemen, T | 1 |
| Yis, U | 1 |
| Khouzam, HR | 1 |
| Lin, CC | 1 |
| Lin, PY | 1 |
| Lee, Y | 1 |
| Chang, YY | 1 |
| Chen, CH | 1 |
| Ozdemir, O | 1 |
| Baytan, B | 1 |
| Gunes, AM | 1 |
| Okan, M | 1 |
| Viana, Bde M | 1 |
| Prais, HA | 1 |
| Camargos, ST | 1 |
| Cardoso, FE | 1 |
| Kutlu, A | 1 |
| Dündar, S | 1 |
| Altun, NS | 1 |
| Budak, F | 1 |
| Collins, KO | 1 |
| Comer, JB | 1 |
| Wonodi, I | 1 |
| Adami, H | 1 |
| Sherr, J | 1 |
| Avila, M | 1 |
| Hong, LE | 1 |
| Thaker, GK | 2 |
| Duggal, HS | 1 |
| Mendhekar, DN | 1 |
| Nieves, JE | 1 |
| Stack, KM | 1 |
| Harrison, ME | 1 |
| Gorman, JM | 1 |
| Yamamoto, N | 1 |
| Oda, T | 1 |
| Inada, T | 1 |
| Bobruff, A | 1 |
| Gardos, G | 1 |
| Tarsy, D | 1 |
| Rapkin, RM | 1 |
| Cole, JO | 1 |
| Moore, P | 1 |
| Chouinard, G | 2 |
| Young, SN | 1 |
| Annable, L | 1 |
| Barnes, TR | 1 |
| Kidger, T | 1 |
| Northcott, C | 1 |
| Lunn, V | 1 |
| Yatham, LN | 1 |
| Ondo, WG | 1 |
| Hurwitz, BJ | 1 |
| Gerding, LB | 1 |
| Labbate, LA | 1 |
| Bassitt, DP | 1 |
| de Souza Lobo Garcia, L | 1 |
| Ozer, EA | 1 |
| Turker, M | 1 |
| Bakiler, AR | 1 |
| Yaprak, I | 1 |
| Ozturk, C | 1 |
| Fukasawa, T | 1 |
| Takahashi, M | 1 |
| Otani, K | 1 |
| O'Connor, M | 1 |
| Rooney, MD | 1 |
| Nienaber, CP | 1 |
| Saltz, BL | 1 |
| Nguyen, JA | 1 |
| Strauss, ME | 1 |
| Jacobson, R | 1 |
| Kaup, BA | 1 |
| Tamminga, CA | 1 |
| Sandyk, R | 2 |
| Kutcher, S | 1 |
| Williamson, P | 1 |
| MacKenzie, S | 1 |
| Marton, P | 1 |
| Ehrlich, M | 1 |
| Horiguchi, J | 1 |
| Inami, Y | 1 |
| Troung, DD | 1 |
| Bressman, S | 1 |
| Shale, H | 1 |
| Fahn, S | 1 |
| Fisher, H | 1 |
2 reviews available for clonazepam and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Benzodiazepines for antipsychotic-induced tardive dyskinesia.
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Clonazepam; Dyskinesia, Drug-Induced; GA | 2018 |
Identification and management of tardive dyskinesia: A case series and literature review.
Topics: Adult; Aged; Anti-Dyskinesia Agents; Clonazepam; Diagnosis, Differential; Dopamine Antagonists; Dysk | 2015 |
7 trials available for clonazepam and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Naltrexone treatment of tardive dyskinesia in patients with schizophrenia.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Clonazepam; Cross-Over Studies; Double-Blind Meth | 2004 |
Antimanic effect of clonazepam.
Topics: Acute Disease; Adult; Affective Disorders, Psychotic; Benzodiazepinones; Bipolar Disorder; Clonazepa | 1983 |
Clonazepam treatment of tardive dyskinesia: a practical GABAmimetic strategy.
Topics: Adult; Antipsychotic Agents; Athetosis; Chorea; Clonazepam; Double-Blind Method; Dyskinesia, Drug-In | 1990 |
A placebo-controlled clinical trial of remoxipride and chlorpromazine in newly admitted schizophrenic patients with acute exacerbation.
Topics: Acute Disease; Adolescent; Adult; Antipsychotic Agents; Benzamides; Chlorpromazine; Clonazepam; Dose | 1990 |
Successful clonazepam treatment of neuroleptic-induced akathisia in older adolescents and young adults: a double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Bipolar Disorder; Clonazepam; Doub | 1989 |
Effect of clonazepam on neuroleptic-induced oculogyric crisis.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Clonazepam; Dyskinesia, Drug-Induced; Eye Mov | 1989 |
Clonazepam, haloperidol, and clonidine in tic disorders.
Topics: Child; Clinical Trials as Topic; Clonazepam; Clonidine; Drug Therapy, Combination; Dyskinesia, Drug- | 1988 |
21 other studies available for clonazepam and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Involuntary movements misdiagnosed as seizure during vitamin B12 treatment.
Topics: Atrophy; Brain; Breast Feeding; Clonazepam; Diagnostic Errors; Dyskinesia, Drug-Induced; Electroence | 2013 |
Tardive dystonia and tardive sensory syndrome related to trazodone: a case report.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Anxiety Disorders; Clonazepam; Dys | 2008 |
Involuntary movements during vitamin B12 treatment.
Topics: Anticonvulsants; Clonazepam; Dyskinesia, Drug-Induced; Female; Humans; Infant; Male; Piracetam; Seve | 2010 |
Ziprasidone-related oculogyric crisis in an adult.
Topics: Adult; Antipsychotic Agents; Clonazepam; Dyskinesia, Drug-Induced; Electroencephalography; Female; G | 2009 |
Ziprasidone induced tardive cervical dystonia.
Topics: Antipsychotic Agents; Botulinum Toxins, Type A; Clonazepam; Depressive Disorder; Dyskinesia, Drug-In | 2009 |
Maternal haloperidol therapy associated with dyskinesia in a newborn.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Clonazepam; Dyskinesia, Drug-Induced; Female; Haloperi | 2003 |
Clozapine-induced tardive dystonia (blepharospasm).
Topics: Anticonvulsants; Antipsychotic Agents; Blepharospasm; Blinking; Clonazepam; Clozapine; Dyskinesia, D | 2007 |
Dysphagia: a rare form of dyskinesia?
Topics: Anticonvulsants; Antipsychotic Agents; Clonazepam; Deglutition Disorders; Dyskinesia, Drug-Induced; | 2007 |
Methamphetamine psychosis in which tardive dystonia was successfully treated with clonazepam.
Topics: Aged; Anti-Dyskinesia Agents; Antipsychotic Agents; Benzodiazepines; Biperiden; Central Nervous Syst | 2007 |
Clonazepam and phenobarbital in tardive dyskinesia.
Topics: Adult; Antipsychotic Agents; Benzodiazepinones; Clonazepam; Dose-Response Relationship, Drug; Double | 1981 |
Clonazepam and tardive dyskinesia.
Topics: Benzodiazepinones; Clonazepam; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Phenobar | 1981 |
Parkinsonism and bipolar affective disorder.
Topics: Aged; Antiparkinson Agents; Bipolar Disorder; Carbidopa; Clonazepam; Dopamine; Drug Combinations; Dr | 1995 |
Tardive dyskinesia and pseudo-parkinsonism. In a nursing home patient who itched.
Topics: Aged; Clonazepam; Dyskinesia, Drug-Induced; Extrapyramidal Tracts; Female; Humans; Parkinson Disease | 1993 |
Use of clonazepam in an elderly bipolar patient with tardive dyskinesia: a case report.
Topics: Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Bipolar Disorder; Clonazepam; Dyskinesia | 1999 |
Risperidone-induced tardive dyskinesia.
Topics: Adult; Anti-Dyskinesia Agents; Antipsychotic Agents; Biperiden; Blepharospasm; Botulinum Toxins; Clo | 2000 |
Involuntary movements in infantile cobalamin deficiency appearing after treatment.
Topics: Anticonvulsants; Breast Feeding; Clonazepam; Diagnosis, Differential; Dyskinesia, Drug-Induced; Fema | 2001 |
A successful clonazepam treatment without tolerance in a patient with spontaneous oral dyskinesia.
Topics: Aged; Anticonvulsants; Clonazepam; Drug Tolerance; Dyskinesia, Drug-Induced; Female; Humans | 2001 |
Neuroleptic-induced dislocation of the jaw.
Topics: Adult; Clonazepam; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Haloperidol; Humans; Joint D | 1992 |
Tardive dyskinesia in the elderly patient.
Topics: Aged; Chlorpromazine; Chronic Disease; Clonazepam; Clozapine; Depressive Disorder; Desipramine; Diph | 1992 |
Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen.
Topics: Baclofen; Causalgia; Clonazepam; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Humans; | 1990 |
Clonazepam-haloperidol therapy in schizophrenia.
Topics: Clonazepam; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Haloperidol; Humans; Schizophrenia | 1988 |