clonazepam has been researched along with Drug Refractory Epilepsy in 3 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "People with drug-refractory epilepsy have increased risks of premature death, injuries, psychosocial dysfunction, and a reduced quality of life." | 2.58 | Clonazepam add-on therapy for refractory epilepsy in adults and children. ( Ji, H; Jia, Y; Liu, F; Liu, Y; Song, L; Zhang, R, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Song, L | 2 |
| Liu, F | 2 |
| Liu, Y | 2 |
| Zhang, R | 2 |
| Ji, H | 2 |
| Jia, Y | 2 |
| Fu, K | 1 |
| Zhou, D | 1 |
| Tang, X | 1 |
| Chen, L | 1 |
3 reviews available for clonazepam and Drug Refractory Epilepsy
| Article | Year |
|---|---|
Clonazepam add-on therapy for drug-resistant epilepsy.
Topics: Adult; Anticonvulsants; Child; Clonazepam; Drug Resistant Epilepsy; Humans | 2020 |
Clonazepam add-on therapy for refractory epilepsy in adults and children.
Topics: Adult; Anticonvulsants; Child; Clonazepam; Drug Resistant Epilepsy; Humans | 2018 |
Clonazepam needs to be taken care for refractory epilepsy: a rare case and review.
Topics: Child; Clonazepam; Drug Resistant Epilepsy; Electroencephalography; GABA Modulators; Humans; Male | 2015 |