Page last updated: 2024-10-25

clonazepam and Drug Overdose

clonazepam has been researched along with Drug Overdose in 11 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"Neither diazepam nor other ligands for benzodiazepine binding sites protect against or attenuate chloroquine cardiotoxicity."3.96Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam. ( Hughes, DA, 2020)
" Following treatment for hyperkalemia with calcium, insulin, dextrose, and hypertonic sodium bicarbonate a repeat ECG had a ventricular rate of 66/min, QRS 156 ms, and QT 576 ms."3.83Not your regular high: cardiac dysrhythmias caused by loperamide. ( Biary, R; Hoffman, RS; Howland, MA; Lugassy, D; Rice, B; Wightman, RS, 2016)
"One patient died of pulmonary edema and subsequent heart failure, but the rest of the patients recovered without any sequelae."1.34Hemoperfusion in the treatment of acute clozapine intoxication in China. ( Cai, ZJ; He, JL; Li, WB; Ungvari, GS; Xiang, YT, 2007)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's5 (45.45)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Lodhi, FAK1
Shogren, SL1
Vedre, JG1
Haque, N1
Reriani, M1
Ali, R1
Hughes, DA1
Bhupali, C1
Cummings, BM1
Parker, L1
Young, R1
Noviski, N1
Kyong, YY1
Park, JT1
Choi, KH1
Wightman, RS1
Hoffman, RS1
Howland, MA1
Rice, B1
Biary, R1
Lugassy, D1
Ramdas, S1
Riesenberg, LA1
Jasani, N1
Huston, B1
Mills, K1
Froloff, V1
McGee, M1
Akhtar, M1
Goldschlager, NF1
Rajkumar, AP1
Jebaraj, P1
Tharyan, P1
He, JL1
Xiang, YT1
Li, WB1
Cai, ZJ1
Ungvari, GS1
Mordel, A1
Winkler, E1
Almog, S1
Tirosh, M1
Ezra, D1

Other Studies

11 other studies available for clonazepam and Drug Overdose

ArticleYear
Calcium Channel Blocker Toxicity Causing Acute Respiratory Distress Syndrome: A Commonly Used Drug Triggering a Life-Threatening Condition.
    WMJ : official publication of the State Medical Society of Wisconsin, 2020, Volume: 119, Issue:1

    Topics: Adult; Anticonvulsants; Calcium Channel Blockers; Clonazepam; Drug Overdose; Female; Humans; Respira

2020
Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam.
    British journal of pharmacology, 2020, Volume: 177, Issue:21

    Topics: Animals; Arrhythmias, Cardiac; Benzodiazepinones; Cardiotoxicity; Chloroquine; Clonazepam; Coronavir

2020
Positive lidocaine toxicology screen after J-Tip for venipuncture.
    Pediatric emergency care, 2013, Volume: 29, Issue:12

    Topics: Anesthetics, Local; Child, Preschool; Clonazepam; Consciousness Disorders; Drug Overdose; Emergency

2013
Serial monitoring of sedation scores in benzodiazepine overdose.
    The American journal of emergency medicine, 2014, Volume: 32, Issue:11

    Topics: Aged; Anticonvulsants; Antidotes; Clonazepam; Drug Overdose; Female; Flumazenil; Humans; Monitoring,

2014
Not your regular high: cardiac dysrhythmias caused by loperamide.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:5

    Topics: Alcoholism; Arrhythmias, Cardiac; Benzodiazepines; Blood Pressure; Calcium; Central Nervous System;

2016
Drug overdose with refractory bradycardia and hypotension.
    Delaware medical journal, 2011, Volume: 83, Issue:6

    Topics: Antihypertensive Agents; Bradycardia; Clonazepam; Diltiazem; Drug Overdose; Female; GABA Modulators;

2011
Bladder rupture after intentional medication overdose.
    The American journal of forensic medicine and pathology, 2012, Volume: 33, Issue:2

    Topics: Carisoprodol; Central Nervous System Depressants; Clonazepam; Drug Overdose; Fatal Outcome; Female;

2012
Brugada electrocardiographic pattern due to tricyclic antidepressant overdose.
    Journal of electrocardiology, 2006, Volume: 39, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Bundle-Branch Block; Clonazepam; Desipramine; Drug Combinat

2006
Multi-drug overdose risperidone, ziprasidone, valproate, trihexyphenidyl, and clonazepam.
    The Journal of the Association of Physicians of India, 2007, Volume: 55

    Topics: Adult; Antipsychotic Agents; Clonazepam; Drug Overdose; Drug Prescriptions; Female; Humans; Piperazi

2007
Hemoperfusion in the treatment of acute clozapine intoxication in China.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:6

    Topics: Acute Disease; Adult; Alprazolam; Antipsychotic Agents; China; Clonazepam; Clozapine; Depressive Dis

2007
Seizures after flumazenil administration in a case of combined benzodiazepine and tricyclic antidepressant overdose.
    Critical care medicine, 1992, Volume: 20, Issue:12

    Topics: Adult; Clonazepam; Diazepam; Drug Overdose; Epilepsy, Tonic-Clonic; Female; Flumazenil; Humans; Imip

1992