clonazepam has been researched along with Dementia in 5 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The tolerability of clonazepam in geropsychiatric inpatients was examined in patients with and without a diagnosis of dementia." | 3.69 | Tolerability of clonazepam in demented and non-demented geropsychiatric patients. ( Calkin, PA; Kunik, ME; Molinari, V; Orengo, CA; Workman, R, 1997) |
| "Clonazepam treatment of RBD was completely or partially successful in 87% of the patients who used the drug." | 1.31 | Rapid eye movement sleep behaviour disorder: demographic, clinical and laboratory findings in 93 cases. ( Boeve, BF; Olson, EJ; Silber, MH, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iranzo, A | 2 |
| Ramos, LA | 1 |
| Novo, S | 1 |
| Fernández-Arcos, A | 1 |
| Serradell, M | 1 |
| Gaig, C | 1 |
| Santamaria, J | 1 |
| Calkin, PA | 1 |
| Kunik, ME | 1 |
| Orengo, CA | 1 |
| Molinari, V | 1 |
| Workman, R | 1 |
| Olson, EJ | 1 |
| Boeve, BF | 1 |
| Silber, MH | 1 |
| Rennert, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Clonazepam on REM Sleep Behavior Disorder in Patients With Parkinsonism: a Prospective, Randomized, Double-blind and Placebo-controlled Trial[NCT02312908] | Phase 2 | 40 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for clonazepam and Dementia
| Article | Year |
|---|---|
The Isolated Form of Rapid Eye Movement Sleep Behavior Disorder: The Upcoming Challenges.
Topics: Clonazepam; Dementia; Diagnostic Tests, Routine; Humans; Melatonin; Parkinson Disease; REM Sleep Beh | 2021 |
4 other studies available for clonazepam and Dementia
| Article | Year |
|---|---|
The Clinical Phenotype of Idiopathic Rapid Eye Movement Sleep Behavior Disorder at Presentation: A Study in 203 Consecutive Patients.
Topics: Aged; Aged, 80 and over; Clonazepam; Continuous Positive Airway Pressure; Dementia; Electromyography | 2016 |
Tolerability of clonazepam in demented and non-demented geropsychiatric patients.
Topics: Aged; Anticonvulsants; Anxiety; Clonazepam; Dementia; Geriatric Psychiatry; Humans; Male; Memory; Mi | 1997 |
Rapid eye movement sleep behaviour disorder: demographic, clinical and laboratory findings in 93 cases.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Aging; Anticonvulsants; Atrophy; Brain; Clonazepam; De | 2000 |
[Some suggestions on epileptic psychoses, their differential diagnosis and therapy].
Topics: Anticonvulsants; Antipsychotic Agents; Clonazepam; Dementia; Diagnosis, Differential; Diazepam; Drug | 1986 |