clonazepam has been researched along with Deficiency, Mental in 15 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Behavioral side effects associated with clonazepam may include agitation, aggression, hyperactivity, irritability, property destruction, and temper tantrums." | 3.72 | Brief report: clonazepam behavioral side effects with an individual with mental retardation. ( Hanzel, TE; Harder, SR; Kalachnik, JE; Sevenich, R, 2003) |
| "To study the risk of intellectual disability and delayed development in childhood milestones among children of women who used valproate or other AEDs during pregnancy." | 1.56 | Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones. ( Christensen, J; Daugaard, CA; Dreier, JW; Pedersen, L; Sun, Y, 2020) |
| "FOXG1 syndrome is a severe encephalopathy that exhibit intellectual disability, emotional disorder, and limited social communication." | 1.51 | Loss of Foxg1 Impairs the Development of Cortical SST-Interneurons Leading to Abnormal Emotional and Social Behaviors. ( Chen, D; Chen, H; Li, M; She, X; Wang, C; Yuan, Y; Zhang, W; Zhao, C, 2019) |
| "Clonazepam was added to carbamazepin, and haloperidol was discontinued." | 1.30 | [Clonazepam therapy of aberrant behavior in a mentally retarded man]. ( Holden, B, 1997) |
| "Strychnine treatment was initiated because it is a specific antagonist of glycine at postsynaptic membranes." | 1.26 | Strychnine therapy in nonketotic hyperglycinemia. ( Arneson, D; Ch'ien, LT; Chance, P; Wilroy, RS, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Daugaard, CA | 1 |
| Pedersen, L | 1 |
| Sun, Y | 1 |
| Dreier, JW | 1 |
| Christensen, J | 1 |
| Chen, D | 1 |
| Wang, C | 1 |
| Li, M | 1 |
| She, X | 1 |
| Yuan, Y | 1 |
| Chen, H | 1 |
| Zhang, W | 1 |
| Zhao, C | 1 |
| Maeda, S | 1 |
| Tomoyasu, Y | 1 |
| Higuchi, H | 1 |
| Ishii-Maruhama, M | 1 |
| Egusa, M | 1 |
| Miyawaki, T | 1 |
| Burlina, AP | 1 |
| Edini, C | 1 |
| Burlina, AB | 1 |
| Kaga, M | 1 |
| Horimoto, R | 1 |
| Hatori, T | 1 |
| Kalachnik, JE | 1 |
| Hanzel, TE | 1 |
| Sevenich, R | 1 |
| Harder, SR | 1 |
| Fernández-Torre, JL | 1 |
| Leno, C | 1 |
| Hirvasniemi, A | 1 |
| Herrala, P | 1 |
| Leisti, J | 1 |
| Holden, B | 1 |
| Nakamura, M | 1 |
| Yamagata, T | 1 |
| Momoi, MY | 1 |
| Yamazaki, T | 1 |
| Arneson, D | 1 |
| Ch'ien, LT | 1 |
| Chance, P | 1 |
| Wilroy, RS | 1 |
| Menkes, JH | 1 |
| Berman, W | 1 |
| Sovner, R | 1 |
| Freinhar, JP | 1 |
1 review available for clonazepam and Deficiency, Mental
| Article | Year |
|---|---|
[Progressive epilepsy with mental retardation(PEMR)].
Topics: Animals; Child; Child, Preschool; Chromosomes, Human, Pair 8; Clonazepam; Diagnosis, Differential; D | 2002 |
14 other studies available for clonazepam and Deficiency, Mental
| Article | Year |
|---|---|
Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Denmark; Developmen | 2020 |
Loss of Foxg1 Impairs the Development of Cortical SST-Interneurons Leading to Abnormal Emotional and Social Behaviors.
Topics: Animals; Behavior, Animal; Brain Diseases; Cerebral Cortex; Clonazepam; Cognition; Depression; Emoti | 2019 |
Independent predictors of delay in emergence from general anesthesia.
Topics: Adult; Ambulatory Care; Anesthesia, Dental; Anesthesia, General; Anesthetics, Inhalation; Anesthetic | 2015 |
Treatment of extrapyramidal symptoms in a patient with homozygous homocystinuria.
Topics: Adult; Anticonvulsants; Clonazepam; Cystathionine beta-Synthase; Dystonia; Female; Homocysteine; Hom | 2002 |
Brief report: clonazepam behavioral side effects with an individual with mental retardation.
Topics: Aggression; Anticonvulsants; Clonazepam; Humans; Intellectual Disability; Male; Mental Disorders; Mi | 2003 |
Teaching NeuroImage: Simple partial frontal status epilepticus with recurrent asymmetric tonic seizures.
Topics: Adult; Anticonvulsants; Atrophy; Clinical Protocols; Clonazepam; Drug Combinations; Electroencephalo | 2008 |
Northern epilepsy syndrome: clinical course and the effect of medication on seizures.
Topics: Adolescent; Adult; Age Factors; Age of Onset; Anticonvulsants; Central Nervous System Diseases; Chil | 1995 |
[Clonazepam therapy of aberrant behavior in a mentally retarded man].
Topics: Anticonvulsants; Behavior; Clonazepam; Humans; Intellectual Disability; Male | 1997 |
Drop episodes in Coffin-Lowry syndrome: exaggerated startle responses treated with clonazepam.
Topics: Abnormalities, Multiple; Adult; Anticonvulsants; Clonazepam; Electroencephalography; Electromyograph | 1998 |
Strychnine therapy in nonketotic hyperglycinemia.
Topics: Benzoates; Clonazepam; Drug Therapy, Combination; Electroencephalography; Enzymes; Female; Glycine; | 1979 |
Diagnosis and treatment of minor motor seizures.
Topics: Child; Child, Preschool; Clonazepam; Electroencephalography; Epilepsy; Epilepsy, Absence; Humans; In | 1976 |
Letter: The ketogenic diet, West and Lennox syndromes.
Topics: Child; Child, Preschool; Clonazepam; Diazepam; Humans; Infant; Intellectual Disability; Myoclonus; N | 1975 |
Clonazepam in the treatment of mentally retarded persons.
Topics: Clonazepam; Female; Humans; Impulsive Behavior; Intellectual Disability; Mood Disorders | 1986 |
Clonazepam treatment of a mentally retarded woman.
Topics: Acting Out; Adult; Benzodiazepinones; Clonazepam; Drug Administration Schedule; Female; Humans; Inte | 1985 |