clonazepam has been researched along with Convulsive Generalized Seizure Disorder in 12 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effect of low-dose clonazepam (CZP) on the amount of epileptiform activity in children with focal and generalized epilepsy." | 9.09 | Reduction of epileptiform activity in response to low-dose clonazepam in children with epilepsy: a randomized double-blind study. ( Amark, P; Dahlin, M; Knutsson, E; Nergårdh, A, 2000) |
| "To evaluate the effect of low-dose clonazepam (CZP) on the amount of epileptiform activity in children with focal and generalized epilepsy." | 5.09 | Reduction of epileptiform activity in response to low-dose clonazepam in children with epilepsy: a randomized double-blind study. ( Amark, P; Dahlin, M; Knutsson, E; Nergårdh, A, 2000) |
| "During her first pregnancy, a 37-year-old woman with idiopathic generalised epilepsy that was adequately controlled with lamotrigine experienced a series of epileptic seizures following an elective caesarean section." | 3.73 | [Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy]. ( Bloem, BR; Renier, WO; Voermans, NC; Zwarts, MJ, 2005) |
| "Herein, we present a 13-year-old generalized epilepsy patient with eating-induced generalized seizures since the age of 5." | 1.62 | Eight years follow-up of a generalized epilepsy patient with eating-induced late-onset epileptic spasms and atypical absence with myoclonic jerks. ( Chen, B; Jin, L; Liu, Y; Wang, X; Zhang, W, 2021) |
| "Beckwith-Wiedemann syndrome (BWS) is etiologically connected with genetic/epigenetic growth dysregulation." | 1.40 | [Case of combination of Beckwith-Wiedemann syndrome with West syndrome]. ( Globa, OV; Kremenchugskaya, MR; Kuzenkova, LM; Podkletnova, TV, 2014) |
| "Clonazepam injection was used to suppress the AS episode and the subintrant myoclonia." | 1.35 | [Idiopathic generalised epilepsies in the elderly: the viewpoint of a geriatrician]. ( Adam, C; Lavallard-Rousseau, MC; Nguyen-Michel, VH; Ourabah, Z; Sebban, C, 2009) |
| "Epilepsy was most common among those with maternal deletions and unknown subtypes, with catastrophic epilepsies present in only these two subtypes." | 1.35 | Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options. ( Braun, EK; Bruno, P; Conant, KD; Nespeca, MP; Said, RR; Thibert, RL; Thiele, EA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Chen, B | 1 |
| Jin, L | 1 |
| Zhang, W | 1 |
| Liu, Y | 1 |
| Samarut, É | 1 |
| Swaminathan, A | 1 |
| Riché, R | 1 |
| Liao, M | 1 |
| Hassan-Abdi, R | 1 |
| Renault, S | 1 |
| Allard, M | 1 |
| Dufour, L | 1 |
| Cossette, P | 1 |
| Soussi-Yanicostas, N | 1 |
| Drapeau, P | 1 |
| Kuzenkova, LM | 1 |
| Kremenchugskaya, MR | 1 |
| Globa, OV | 1 |
| Podkletnova, TV | 1 |
| Nguyen-Michel, VH | 1 |
| Ourabah, Z | 1 |
| Sebban, C | 1 |
| Lavallard-Rousseau, MC | 1 |
| Adam, C | 1 |
| Thibert, RL | 1 |
| Conant, KD | 1 |
| Braun, EK | 1 |
| Bruno, P | 1 |
| Said, RR | 1 |
| Nespeca, MP | 1 |
| Thiele, EA | 1 |
| Dahlin, MG | 1 |
| Amark, PE | 1 |
| Nergårdh, AR | 1 |
| Wheless, JW | 1 |
| Voermans, NC | 1 |
| Zwarts, MJ | 1 |
| Renier, WO | 1 |
| Bloem, BR | 1 |
| Duval, X | 1 |
| Chosidow, O | 1 |
| Semah, F | 1 |
| Lipsker, D | 1 |
| Francès, C | 1 |
| Herson, S | 1 |
| Obeid, T | 1 |
| Awada, A | 1 |
| Sayes, N | 1 |
| Mousali, Y | 1 |
| Harris, C | 1 |
| Dahlin, M | 1 |
| Knutsson, E | 1 |
| Amark, P | 1 |
| Nergårdh, A | 1 |
| Kmieć, T | 1 |
| Jóźwiak, S | 1 |
| Kuczyński, D | 1 |
| Karkowska, B | 1 |
| Bachański, M | 1 |
1 review available for clonazepam and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Acute management of seizures in the syndromes of idiopathic generalized epilepsies.
Topics: Acute Disease; Adolescent; Adult; Anticonvulsants; Clonazepam; Comorbidity; Drug Administration Sche | 2003 |
3 trials available for clonazepam and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Reduction of seizures with low-dose clonazepam in children with epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Clonazepam; Epilepsies, Partial; Epilepsy, Gen | 2003 |
Reduction of epileptiform activity in response to low-dose clonazepam in children with epilepsy: a randomized double-blind study.
Topics: Anticonvulsants; Child; Child, Preschool; Clonazepam; Cross-Over Studies; Double-Blind Method; Drug | 2000 |
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combi | 2000 |
8 other studies available for clonazepam and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Eight years follow-up of a generalized epilepsy patient with eating-induced late-onset epileptic spasms and atypical absence with myoclonic jerks.
Topics: Adolescent; China; Clonazepam; Eating; Epilepsy, Generalized; Follow-Up Studies; Humans; Male; Myocl | 2021 |
γ-Aminobutyric acid receptor alpha 1 subunit loss of function causes genetic generalized epilepsy by impairing inhibitory network neurodevelopment.
Topics: Animals; Animals, Genetically Modified; Anticonvulsants; Brain; Clonazepam; Disease Models, Animal; | 2018 |
[Case of combination of Beckwith-Wiedemann syndrome with West syndrome].
Topics: Anticonvulsants; Beckwith-Wiedemann Syndrome; Child; Clonazepam; Electroencephalography; Epilepsy, G | 2014 |
[Idiopathic generalised epilepsies in the elderly: the viewpoint of a geriatrician].
Topics: Aged; Aged, 80 and over; Anticonvulsants; Clonazepam; Electroencephalography; Epilepsy, Generalized; | 2009 |
Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options.
Topics: Adolescent; Adult; Angelman Syndrome; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbid | 2009 |
[Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy].
Topics: Adult; Anticonvulsants; Cesarean Section; Clonazepam; Diazepam; Epilepsy; Epilepsy, Generalized; Epi | 2005 |
Lamotrigine versus carbamazepine in epilepsy.
Topics: Adult; Anticonvulsants; Clonazepam; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigi | 1995 |
A unique effect of clonazepam on frontal lobe seizure control.
Topics: Adolescent; Anticonvulsants; Clonazepam; Epilepsy, Generalized; Female; Frontal Lobe; Humans | 1999 |