clonazepam has been researched along with Cocaine Abuse in 1 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlormethiazole also was tested against the expression (anticonvulsant effect) and development (antiepileptogenic effect) of cocaine-kindled seizures, and against fully developed kindled seizures." | 1.31 | Chlormethiazole: effectiveness against toxic effects of cocaine in mice. ( Gasior, M; Ungard, JT; Witkin, JM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gasior, M | 1 |
| Ungard, JT | 1 |
| Witkin, JM | 1 |
1 other study available for clonazepam and Cocaine Abuse
| Article | Year |
|---|---|
Chlormethiazole: effectiveness against toxic effects of cocaine in mice.
Topics: Animals; Anticonvulsants; Chlormethiazole; Clonazepam; Cocaine; Cocaine-Related Disorders; Dose-Resp | 2000 |