clonazepam has been researched along with Chorea in 17 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Chorea: Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The studies reported 22 different treatments for chorea, including carbidopa/levodopa, tetrabenazine, clonazepam, methylphenidate, carbamazepine, topiramate, trihexyphenidyl, haloperidol, propranolol, risperidone, and valproate." | 5.41 | Systematic review of drug therapy for chorea in NXK2-1-related disorders: Efficacy and safety evidence from case studies and series. ( Bachoud-Lévi, AC; Blasco-Amaro, JA; Capuano, A; Isabel-Gómez, R; Martín-Gómez, C; Nou-Fontanet, L; Ortigoza-Escobar, JD; Zorzi, G, 2023) |
| "In a limited study, clonazepam, a new benzodiazepine derivative, has been found to be effective in suppressing choreiform movements in three patients with Huntington's chorea, three patients with non-familial chorea, and in one patient with senile chorea." | 3.65 | Clonazepam in the treatment of choreiform activity. ( Boralessa, H; Lionel, ND; Peiris, JB, 1976) |
| " Tolerance developed to the antidyskinetic effect of clonazepam in the five patients whose long-term use of the drug was followed, but a 2-week clonazepam-free period recaptured its antidyskinetic effect." | 2.67 | Clonazepam treatment of tardive dyskinesia: a practical GABAmimetic strategy. ( Jacobson, R; Kaup, BA; Nguyen, JA; Strauss, ME; Tamminga, CA; Thaker, GK, 1990) |
| "In symptomatic paroxysmal dyskinesias, the treatment of the underlying disease will provide best results." | 2.47 | Treatment of paroxysmal dyskinesias. ( Bürk, K; Oertel, WH; Strzelczyk, A, 2011) |
| "Two patients who developed choreoathetosis in the course of lithium treatment are described, and other cases of choreoathetosis in lithium-treated patients are reviewed." | 2.38 | Choreoathetosis: a sign of lithium toxicity. ( Reed, SM; Timmerman, I; Wise, MG, 1989) |
| "Non-ketotic hyperglycaemic hemichorea-hemiballismus (NHHH) is commonly seen among elderly Asian women with type 2 diabetes mellitus." | 1.48 | Paediatric non-ketotic hyperglycaemic hemichorea-hemiballismus. ( Benitez, JAEL; Sacro, CAL; Suratos, CTR; Urquiza, SC, 2018) |
| "Clonazepam was stopped in 2 weeks and chorea did not recur." | 1.46 | Case report of hyperglycemic nonketotic chorea with rapid radiological resolution. ( Herath, HMMTB; Pahalagamage, SP; Senanayake, S, 2017) |
| "The four classic categories of paroxysmal dyskinesias are kinesigenic, nonkinesigenic, exercise-induced and hypnogenic." | 1.40 | A rare paroxysmal movement disorder: mixed type of paroxysmal dyskinesia. ( Arpaci, B; Atakli, D; Guresci, B; Sen, A, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Nou-Fontanet, L | 1 |
| Martín-Gómez, C | 1 |
| Isabel-Gómez, R | 1 |
| Bachoud-Lévi, AC | 1 |
| Zorzi, G | 1 |
| Capuano, A | 1 |
| Blasco-Amaro, JA | 1 |
| Ortigoza-Escobar, JD | 1 |
| Herath, HMMTB | 1 |
| Pahalagamage, SP | 1 |
| Senanayake, S | 1 |
| Suratos, CTR | 1 |
| Benitez, JAEL | 1 |
| Urquiza, SC | 1 |
| Sacro, CAL | 1 |
| Virmani, T | 1 |
| Greene, PE | 1 |
| Pearson, TS | 1 |
| Sen, A | 1 |
| Atakli, D | 1 |
| Guresci, B | 1 |
| Arpaci, B | 1 |
| Strzelczyk, A | 1 |
| Bürk, K | 1 |
| Oertel, WH | 1 |
| Yeh, TH | 1 |
| Lin, JJ | 1 |
| Lai, SC | 1 |
| Wu-Chou, YH | 1 |
| Chen, AC | 1 |
| Yueh, KC | 1 |
| Chen, RS | 1 |
| Lu, CS | 1 |
| Benbir, G | 1 |
| Senturk, A | 1 |
| Tan, F | 1 |
| Karadeniz, D | 1 |
| Burke, L | 1 |
| Berenberg, RA | 1 |
| Kim, KS | 1 |
| Tibbles, JA | 1 |
| Barnes, SE | 1 |
| Matsuo, H | 1 |
| Okano, M | 1 |
| Kaida, K | 1 |
| Tadano, Y | 1 |
| Kamakura, K | 1 |
| Peiris, JB | 1 |
| Boralessa, H | 1 |
| Lionel, ND | 1 |
| Lance, JW | 1 |
| Thaker, GK | 1 |
| Nguyen, JA | 1 |
| Strauss, ME | 1 |
| Jacobson, R | 1 |
| Kaup, BA | 1 |
| Tamminga, CA | 1 |
| Klinz, C | 1 |
| Biesold, KH | 1 |
| Reed, SM | 1 |
| Wise, MG | 1 |
| Timmerman, I | 1 |
| O'Flaherty, S | 1 |
| Evans, M | 1 |
| Epps, A | 1 |
| Buchanan, N | 1 |
4 reviews available for clonazepam and Chorea
| Article | Year |
|---|---|
Systematic review of drug therapy for chorea in NXK2-1-related disorders: Efficacy and safety evidence from case studies and series.
Topics: Carbidopa; Chorea; Clonazepam; Humans; Levodopa; Methylphenidate; Tetrabenazine | 2023 |
Treatment of paroxysmal dyskinesias.
Topics: Anticonvulsants; Carbamazepine; Chorea; Clonazepam; Humans; Rare Diseases | 2011 |
Familial paroxysmal nonkinesigenic dyskinesia: clinical and genetic analysis of a Taiwanese family.
Topics: Adult; Age of Onset; Amino Acid Sequence; Base Sequence; Caffeine; Child, Preschool; Chorea; Clonaze | 2012 |
Choreoathetosis: a sign of lithium toxicity.
Topics: Aged; Athetosis; Chorea; Clonazepam; Delirium; Depressive Disorder; Drug Therapy, Combination; Femal | 1989 |
1 trial available for clonazepam and Chorea
| Article | Year |
|---|---|
Clonazepam treatment of tardive dyskinesia: a practical GABAmimetic strategy.
Topics: Adult; Antipsychotic Agents; Athetosis; Chorea; Clonazepam; Double-Blind Method; Dyskinesia, Drug-In | 1990 |
12 other studies available for clonazepam and Chorea
| Article | Year |
|---|---|
Case report of hyperglycemic nonketotic chorea with rapid radiological resolution.
Topics: Brain; Child, Preschool; Chorea; Clonazepam; Diabetes Complications; Female; Humans; Hyperglycemia; | 2017 |
Paediatric non-ketotic hyperglycaemic hemichorea-hemiballismus.
Topics: Adolescent; Anti-Dyskinesia Agents; Blood Glucose; Chorea; Clonazepam; Diabetes Mellitus, Type 1; Dy | 2018 |
Delayed onset of progressive chorea after acute basal ganglia injury.
Topics: Adult; Baclofen; Basal Ganglia Diseases; Chorea; Clonazepam; GABA Modulators; Humans; Male; Muscle R | 2013 |
A rare paroxysmal movement disorder: mixed type of paroxysmal dyskinesia.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Chorea; Clonazepam; Diagnosis, Differential; Drug Therap | 2014 |
Polysomnographic recording of a child with paroxysmal hypnogenic dyskinesia and NREM parasomnia.
Topics: Anticonvulsants; Cerebral Cortex; Child; Chorea; Clonazepam; Diagnosis, Differential; Dystonia; Huma | 2013 |
Choreoballismus: a nonhemorrhagic complication of venous angiomas.
Topics: Brain Neoplasms; Caudate Nucleus; Chorea; Clonazepam; Haloperidol; Hemangioma; Humans; Male; Middle | 1984 |
Paroxysmal dystonic choreoathetosis of Mount and Reback.
Topics: Adult; Aged; Athetosis; Child, Preschool; Chorea; Clonazepam; Female; Genes, Dominant; Humans; Male; | 1980 |
[A Japanese family with paroxysmal dystonic choreoathetosis].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Asian People; Athetosis; Caffeine; Child; Chorea; Chromoso | 1997 |
Clonazepam in the treatment of choreiform activity.
Topics: Adult; Aged; Benzodiazepinones; Chorea; Clonazepam; Female; Humans; Huntington Disease; Male; Middle | 1976 |
Familial paroxysmal dystonic choreoathetosis of Mount and Reback and its differentiation from related syndromes.
Topics: Adolescent; Adult; Athetosis; Barbiturates; Child; Child, Preschool; Chorea; Clonazepam; Female; Hum | 1977 |
[Familial paroxysmal dystonic choreoathetosis].
Topics: Adult; Athetosis; Caffeine; Chorea; Clonazepam; Diagnosis, Differential; Dose-Response Relationship, | 1990 |
Choreoathetosis and clonazepam.
Topics: Adolescent; Athetosis; Benzodiazepinones; Chorea; Clonazepam; Epilepsy; Humans; Male; Substance With | 1985 |