Page last updated: 2024-10-25

clonazepam and Chorea Disorders

clonazepam has been researched along with Chorea Disorders in 17 studies

Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Research Excerpts

ExcerptRelevanceReference
" The studies reported 22 different treatments for chorea, including carbidopa/levodopa, tetrabenazine, clonazepam, methylphenidate, carbamazepine, topiramate, trihexyphenidyl, haloperidol, propranolol, risperidone, and valproate."5.41Systematic review of drug therapy for chorea in NXK2-1-related disorders: Efficacy and safety evidence from case studies and series. ( Bachoud-Lévi, AC; Blasco-Amaro, JA; Capuano, A; Isabel-Gómez, R; Martín-Gómez, C; Nou-Fontanet, L; Ortigoza-Escobar, JD; Zorzi, G, 2023)
"In a limited study, clonazepam, a new benzodiazepine derivative, has been found to be effective in suppressing choreiform movements in three patients with Huntington's chorea, three patients with non-familial chorea, and in one patient with senile chorea."3.65Clonazepam in the treatment of choreiform activity. ( Boralessa, H; Lionel, ND; Peiris, JB, 1976)
" Tolerance developed to the antidyskinetic effect of clonazepam in the five patients whose long-term use of the drug was followed, but a 2-week clonazepam-free period recaptured its antidyskinetic effect."2.67Clonazepam treatment of tardive dyskinesia: a practical GABAmimetic strategy. ( Jacobson, R; Kaup, BA; Nguyen, JA; Strauss, ME; Tamminga, CA; Thaker, GK, 1990)
"In symptomatic paroxysmal dyskinesias, the treatment of the underlying disease will provide best results."2.47Treatment of paroxysmal dyskinesias. ( Bürk, K; Oertel, WH; Strzelczyk, A, 2011)
"Two patients who developed choreoathetosis in the course of lithium treatment are described, and other cases of choreoathetosis in lithium-treated patients are reviewed."2.38Choreoathetosis: a sign of lithium toxicity. ( Reed, SM; Timmerman, I; Wise, MG, 1989)
"Non-ketotic hyperglycaemic hemichorea-hemiballismus (NHHH) is commonly seen among elderly Asian women with type 2 diabetes mellitus."1.48Paediatric non-ketotic hyperglycaemic hemichorea-hemiballismus. ( Benitez, JAEL; Sacro, CAL; Suratos, CTR; Urquiza, SC, 2018)
"Clonazepam was stopped in 2 weeks and chorea did not recur."1.46Case report of hyperglycemic nonketotic chorea with rapid radiological resolution. ( Herath, HMMTB; Pahalagamage, SP; Senanayake, S, 2017)
"The four classic categories of paroxysmal dyskinesias are kinesigenic, nonkinesigenic, exercise-induced and hypnogenic."1.40A rare paroxysmal movement disorder: mixed type of paroxysmal dyskinesia. ( Arpaci, B; Atakli, D; Guresci, B; Sen, A, 2014)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19906 (35.29)18.7374
1990's3 (17.65)18.2507
2000's0 (0.00)29.6817
2010's7 (41.18)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Nou-Fontanet, L1
Martín-Gómez, C1
Isabel-Gómez, R1
Bachoud-Lévi, AC1
Zorzi, G1
Capuano, A1
Blasco-Amaro, JA1
Ortigoza-Escobar, JD1
Herath, HMMTB1
Pahalagamage, SP1
Senanayake, S1
Suratos, CTR1
Benitez, JAEL1
Urquiza, SC1
Sacro, CAL1
Virmani, T1
Greene, PE1
Pearson, TS1
Sen, A1
Atakli, D1
Guresci, B1
Arpaci, B1
Strzelczyk, A1
Bürk, K1
Oertel, WH1
Yeh, TH1
Lin, JJ1
Lai, SC1
Wu-Chou, YH1
Chen, AC1
Yueh, KC1
Chen, RS1
Lu, CS1
Benbir, G1
Senturk, A1
Tan, F1
Karadeniz, D1
Burke, L1
Berenberg, RA1
Kim, KS1
Tibbles, JA1
Barnes, SE1
Matsuo, H1
Okano, M1
Kaida, K1
Tadano, Y1
Kamakura, K1
Peiris, JB1
Boralessa, H1
Lionel, ND1
Lance, JW1
Thaker, GK1
Nguyen, JA1
Strauss, ME1
Jacobson, R1
Kaup, BA1
Tamminga, CA1
Klinz, C1
Biesold, KH1
Reed, SM1
Wise, MG1
Timmerman, I1
O'Flaherty, S1
Evans, M1
Epps, A1
Buchanan, N1

Reviews

4 reviews available for clonazepam and Chorea Disorders

ArticleYear
Systematic review of drug therapy for chorea in NXK2-1-related disorders: Efficacy and safety evidence from case studies and series.
    European journal of neurology, 2023, Volume: 30, Issue:12

    Topics: Carbidopa; Chorea; Clonazepam; Humans; Levodopa; Methylphenidate; Tetrabenazine

2023
Treatment of paroxysmal dyskinesias.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:1

    Topics: Anticonvulsants; Carbamazepine; Chorea; Clonazepam; Humans; Rare Diseases

2011
Familial paroxysmal nonkinesigenic dyskinesia: clinical and genetic analysis of a Taiwanese family.
    Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2

    Topics: Adult; Age of Onset; Amino Acid Sequence; Base Sequence; Caffeine; Child, Preschool; Chorea; Clonaze

2012
Choreoathetosis: a sign of lithium toxicity.
    The Journal of neuropsychiatry and clinical neurosciences, 1989,Winter, Volume: 1, Issue:1

    Topics: Aged; Athetosis; Chorea; Clonazepam; Delirium; Depressive Disorder; Drug Therapy, Combination; Femal

1989

Trials

1 trial available for clonazepam and Chorea Disorders

ArticleYear
Clonazepam treatment of tardive dyskinesia: a practical GABAmimetic strategy.
    The American journal of psychiatry, 1990, Volume: 147, Issue:4

    Topics: Adult; Antipsychotic Agents; Athetosis; Chorea; Clonazepam; Double-Blind Method; Dyskinesia, Drug-In

1990

Other Studies

12 other studies available for clonazepam and Chorea Disorders

ArticleYear
Case report of hyperglycemic nonketotic chorea with rapid radiological resolution.
    BMC medical imaging, 2017, 09-12, Volume: 17, Issue:1

    Topics: Brain; Child, Preschool; Chorea; Clonazepam; Diabetes Complications; Female; Humans; Hyperglycemia;

2017
Paediatric non-ketotic hyperglycaemic hemichorea-hemiballismus.
    BMJ case reports, 2018, Apr-05, Volume: 2018

    Topics: Adolescent; Anti-Dyskinesia Agents; Blood Glucose; Chorea; Clonazepam; Diabetes Mellitus, Type 1; Dy

2018
Delayed onset of progressive chorea after acute basal ganglia injury.
    Movement disorders : official journal of the Movement Disorder Society, 2013, Volume: 28, Issue:5

    Topics: Adult; Baclofen; Basal Ganglia Diseases; Chorea; Clonazepam; GABA Modulators; Humans; Male; Muscle R

2013
A rare paroxysmal movement disorder: mixed type of paroxysmal dyskinesia.
    Ideggyogyaszati szemle, 2014, Nov-30, Volume: 67, Issue:11-12

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Chorea; Clonazepam; Diagnosis, Differential; Drug Therap

2014
Polysomnographic recording of a child with paroxysmal hypnogenic dyskinesia and NREM parasomnia.
    Sleep medicine, 2013, Volume: 14, Issue:2

    Topics: Anticonvulsants; Cerebral Cortex; Child; Chorea; Clonazepam; Diagnosis, Differential; Dystonia; Huma

2013
Choreoballismus: a nonhemorrhagic complication of venous angiomas.
    Surgical neurology, 1984, Volume: 21, Issue:3

    Topics: Brain Neoplasms; Caudate Nucleus; Chorea; Clonazepam; Haloperidol; Hemangioma; Humans; Male; Middle

1984
Paroxysmal dystonic choreoathetosis of Mount and Reback.
    Pediatrics, 1980, Volume: 65, Issue:1

    Topics: Adult; Aged; Athetosis; Child, Preschool; Chorea; Clonazepam; Female; Genes, Dominant; Humans; Male;

1980
[A Japanese family with paroxysmal dystonic choreoathetosis].
    Rinsho shinkeigaku = Clinical neurology, 1997, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Asian People; Athetosis; Caffeine; Child; Chorea; Chromoso

1997
Clonazepam in the treatment of choreiform activity.
    The Medical journal of Australia, 1976, Feb-21, Volume: 1, Issue:8

    Topics: Adult; Aged; Benzodiazepinones; Chorea; Clonazepam; Female; Humans; Huntington Disease; Male; Middle

1976
Familial paroxysmal dystonic choreoathetosis of Mount and Reback and its differentiation from related syndromes.
    Transactions of the American Neurological Association, 1977, Volume: 102

    Topics: Adolescent; Adult; Athetosis; Barbiturates; Child; Child, Preschool; Chorea; Clonazepam; Female; Hum

1977
[Familial paroxysmal dystonic choreoathetosis].
    Der Nervenarzt, 1990, Volume: 61, Issue:8

    Topics: Adult; Athetosis; Caffeine; Chorea; Clonazepam; Diagnosis, Differential; Dose-Response Relationship,

1990
Choreoathetosis and clonazepam.
    The Medical journal of Australia, 1985, Apr-15, Volume: 142, Issue:8

    Topics: Adolescent; Athetosis; Benzodiazepinones; Chorea; Clonazepam; Epilepsy; Humans; Male; Substance With

1985