clonazepam has been researched along with Cancer of Prostate in 3 studies
Clonazepam: An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses.
clonazepam : 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We used various prostate cancer cell lines and western blot analysis, qRT-PCR, siRNA, M30 apoptosis assay and immunoprecipitation techniques to determine mechanisms regulating Mfn1." | 1.40 | Mitofusin 1 degradation is induced by a disruptor of mitochondrial calcium homeostasis, CGP37157: a role in apoptosis in prostate cancer cells. ( Alaisami, R; Bollag, WB; Choudhary, V; Kaddour-Djebbar, I; Kumar, MV, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choudhary, V | 2 |
| Kaddour-Djebbar, I | 3 |
| Alaisami, R | 1 |
| Kumar, MV | 3 |
| Bollag, WB | 1 |
| Brooks, C | 1 |
| Ghazaly, T | 1 |
| Lakshmikanthan, V | 2 |
| Dong, Z | 1 |
| Shirley, RB | 1 |
| Ma, Y | 1 |
| Lewis, RW | 1 |
3 other studies available for clonazepam and Cancer of Prostate
| Article | Year |
|---|---|
Mitofusin 1 degradation is induced by a disruptor of mitochondrial calcium homeostasis, CGP37157: a role in apoptosis in prostate cancer cells.
Topics: Apoptosis; Calcium; Cell Line, Tumor; Clonazepam; Cycloheximide; GTP Phosphohydrolases; Humans; Male | 2014 |
Specific mitochondrial calcium overload induces mitochondrial fission in prostate cancer cells.
Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Blotting, Western; Calcium; Cell Line, Tumor; | 2010 |
Therapeutic advantage of combining calcium channel blockers and TRAIL in prostate cancer.
Topics: Androgens; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calcium; Calcium Channel Block | 2006 |